The discovery of odanacatib (MK-0822), a selective inhibitor of cathepsin K
Gauthier, Jacques Yves, Chauret, Nathalie, Cromlish, Wanda, Desmarais, Sylvie, Duong, Le T., Falgueyret, Jean-Pierre, Kimmel, Donald B., Lamontagne, Sonia, Léger, Serge, LeRiche, Tammy, Li, Chun Sing, Massé, Frédéric, McKay, Daniel J., Nicoll-Griffith, Deborah A., Oballa, Renata M., Palmer, James T., Percival, M. David, Riendeau, Denis, Robichaud, Joel, Rodan, Gideon A., Rodan, Sevgi B., Seto, Carmai, Thérien, Michel, Truong, Vouy-Linh, Venuti, Michael C., Wesolowski, Gregg, Young, Robert N., Zamboni, Robert, Black, W. Cameron
Published in Bioorganic & medicinal chemistry (01.02.2008)
Published in Bioorganic & medicinal chemistry (01.02.2008)
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Journal Article
Discovery of a Potent and Selective Prostaglandin D2 Receptor Antagonist, [(3R)-4-(4-Chloro- benzyl)-7-fluoro-5-(methylsulfonyl)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl]-acetic Acid (MK-0524)
Sturino, Claudio F, O'Neill, Gary, Lachance, Nicolas, Boyd, Michael, Berthelette, Carl, Labelle, Marc, Li, Lianhai, Roy, Bruno, Scheigetz, John, Tsou, Nancy, Aubin, Yves, Bateman, Kevin P, Chauret, Nathalie, Day, Stephen H, Lévesque, Jean-François, Seto, Carmai, Silva, Jose H, Trimble, Laird A, Carriere, Marie-Claude, Denis, Danielle, Greig, Gillian, Kargman, Stacia, Lamontagne, Sonia, Mathieu, Marie-Claude, Sawyer, Nicole, Slipetz, Deborah, Abraham, William M, Jones, Tom, McAuliffe, Malia, Piechuta, Hana, Nicoll-Griffith, Deborah A, Wang, Zhaoyin, Zamboni, Robert, Young, Robert N, Metters, Kathleen M
Published in Journal of medicinal chemistry (22.02.2007)
Published in Journal of medicinal chemistry (22.02.2007)
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Journal Article
A generally applicable method for assessing the electrophilicity and reactivity of diverse nitrile-containing compounds
Oballa, Renata M., Truchon, Jean-François, Bayly, Christopher I., Chauret, Nathalie, Day, Stephen, Crane, Sheldon, Berthelette, Carl
Published in Bioorganic & medicinal chemistry letters (15.02.2007)
Published in Bioorganic & medicinal chemistry letters (15.02.2007)
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Journal Article
In Vitro Comparison of Cytochrome P450-Mediated Metabolic Activities in Human, Dog, Cat, and Horse
Chauret, N, Gauthier, A, Martin, J, Nicoll-Griffith, D A
Published in Drug metabolism and disposition (01.10.1997)
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Published in Drug metabolism and disposition (01.10.1997)
Journal Article
Discovery of a potent and selective agonist of the prostaglandin EP4 receptor
BILLOT, Xavier, CHATEAUNEUF, Anne, CHAURET, Nathalie, DENIS, Danielle, GREIG, Gillian, MATHIEU, Marie-Claude, METTERS, Kathleen M, SLIPETZ, Deborah M, YOUNG, Robert N
Published in Bioorganic & medicinal chemistry letters (24.03.2003)
Published in Bioorganic & medicinal chemistry letters (24.03.2003)
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Journal Article
Substituted coumarins as potent 5-lipoxygenase inhibitors
Grimm, Erich L., Brideau, Christine, Chauret, Nathalie, Chan, Chi-Chung, Delorme, Daniel, Ducharme, Yves, Ethier, Diane, Falgueyret, Jean-Pierre, Friesen, Richard W., Guay, Jocelyne, Hamel, Pierre, Riendeau, Denis, Soucy-Breau, Chantal, Tagari, Philip, Girard, Yves
Published in Bioorganic & medicinal chemistry letters (01.05.2006)
Published in Bioorganic & medicinal chemistry letters (01.05.2006)
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Journal Article
Selective isolation of in vitro phase II conjugates using a lipophilic anionic exchange solid phase extraction method
Gagné, Sébastien, Laterreur, Julie, Mahrouche, Louiza, Sørensen, Dan, Gauthier, Jacques Yves, Truong, Vouy Linh, Chauret, Nathalie, Lévesque, Jean-François
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (01.03.2008)
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (01.03.2008)
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Journal Article
Improving metabolic stability of phosphodiesterase-4 inhibitors containing a substituted catechol: prevention of reactive intermediate formation and covalent binding
Chauret, Nathalie, Guay, Daniel, Li, Chun, Day, Stephen, Silva, José, Blouin, Marc, Ducharme, Yves, Yergey, James A., Nicoll-Griffith, Deborah A.
Published in Bioorganic & medicinal chemistry letters (19.08.2002)
Published in Bioorganic & medicinal chemistry letters (19.08.2002)
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Journal Article
Interspecies in vitro metabolism of the phosphodiesterase-4 (PDE4) inhibitor L-454,560
Bateman, Kevin P., Trimble, Laird, Chauret, Nathalie, Silva, Jose, Day, Stephen, Macdonald, Dwight, Dube, Daniel, Gallant, Michel, Mastracchio, Anthony, Perrier, Helene, Girard, Yves, Nicoll-Griffith, Deborah
Published in Journal of mass spectrometry. (01.06.2006)
Published in Journal of mass spectrometry. (01.06.2006)
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Journal Article
Description of a 96-Well Plate Assay to Measure Cytochrome P4503A Inhibition in Human Liver Microsomes Using a Selective Fluorescent Probe
Chauret, Nathalie, Tremblay, Nathalie, Lackman, Rebecca L., Gauthier, Jacques-Yves, Silva, José M., Marois, Jean, Yergey, James A., Nicoll-Griffith, Deborah A.
Published in Analytical biochemistry (15.12.1999)
Published in Analytical biochemistry (15.12.1999)
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Journal Article
DESIGN OF THE LANDMARK CALM-1 AND CALM-2 PHASE 3 CLINICAL TRIALS OF CAMLIPIXANT IN REFRACTORY CHRONIC COUGH
SMITH, JACKY, SMITH, STEVEN G, IYER, VIVEK, SATIA, IMRAN, CHAURET, NATHALIE, HARVEY, LAURENT, YANG, RONGHUA, GARIN, MARGARET, BONUCCELLI, CATHERINE
Published in Chest (01.10.2024)
Published in Chest (01.10.2024)
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Journal Article
Structure-activity relationship studies on ortho-substituted cinnamic acids, a new class of selective EP3 antagonists
BELLEY, Michel, GALLANT, Michel, TREMBLAY, Nathalie, LAMONTAGNE, Sonia, CARRIERE, Marie-Claude, DENIS, Danielle, GREIG, Gillian M, SLIPETZ, Deborah, METTERS, Kathleen M, GORDON, Robert, CHI CHUNG CHAN, ZAMBONI, Robert J, ROY, Bruno, HOUDE, Karine, LACHANCE, Nicolas, LABELLE, Marc, TRIMBLE, Laird A, CHAURET, Nathalie, CHUN LI, SAWYER, Nicole
Published in Bioorganic & medicinal chemistry letters (01.02.2005)
Published in Bioorganic & medicinal chemistry letters (01.02.2005)
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Journal Article
The Use of 3-[2-(N,N-Diethyl-N-methylammonium)ethyl]-7-methoxy-4-methylcoumarin (AMMC) as a Specific CYP2D6 Probe in Human Liver Microsomes
CHAURET, Nathalie, DOBBS, Barry, LACKMAN, Rebecca L, BATEMAN, Kevin, NICOLL-GRIFFITH, Deborah A, STRESSER, David M, ACKERMANN, Joseph M, TURNER, Stephanie D, MILLER, Vaughn P, CRESPI, Charles L
Published in Drug metabolism and disposition (01.09.2001)
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Published in Drug metabolism and disposition (01.09.2001)
Journal Article
Erratum to “Evaluation of human hepatocyte incubation as a new tool for metabolism study of androstenedione and norandrostenedione in a doping control perspective”: [J. Chromatogr. B. 780 (2002) 145–153]
Lévesque, Jean-François, Gaudreault, Mireille, Houle, Robert, Chauret, Nathalie
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (25.04.2003)
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (25.04.2003)
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Journal Article
USE OF A BENZYLOXY-SUBSTITUTED LACTONE CYCLOOXYGENASE-2 INHIBITOR AS A SELECTIVE FLUORESCENT PROBE FOR CYP3A ACTIVITY IN PRIMARY CULTURED RAT AND HUMAN HEPATOCYTES
Nicoll-Griffith, Deborah A., Chauret, Nathalie, Houle, Robert, Day, Stephen H., D'Antoni, Michelle, Silva, José M.
Published in Drug metabolism and disposition (01.12.2004)
Published in Drug metabolism and disposition (01.12.2004)
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Journal Article
P2X3 길항제의 제조
GREEN JEREMY, CHAURET NATHALIE, KRONENTHAL DAVID R, VILLENEUVE KARINE
Year of Publication 18.10.2022
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Year of Publication 18.10.2022
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