Decarboxylative borylation
Li, Chao, Wang, Jie, Barton, Lisa M., Yu, Shan, Tian, Maoqun, Peters, David S., Kumar, Manoj, Yu, Antony W., Johnson, Kristen A., Chatterjee, Arnab K., Yan, Ming, Baran, Phil S.
Published in Science (American Association for the Advancement of Science) (09.06.2017)
Published in Science (American Association for the Advancement of Science) (09.06.2017)
Get full text
Journal Article
Antitumor activity of a systemic STING-activating non-nucleotide cGAMP mimetic
Chin, Emily N, Yu, Chenguang, Vartabedian, Vincent F, Jia, Ying, Kumar, Manoj, Gamo, Ana M, Vernier, William, Ali, Sabrina H, Kissai, Mildred, Lazar, Daniel C, Nguyen, Nhan, Pereira, Laura E, Benish, Brent, Woods, Ashley K, Joseph, Sean B, Chu, Alan, Johnson, Kristen A, Sander, Philipp N, Martínez-Peña, Francisco, Hampton, Eric N, Young, Travis S, Wolan, Dennis W, Chatterjee, Arnab K, Schultz, Peter G, Petrassi, H Michael, Teijaro, John R, Lairson, Luke L
Published in Science (American Association for the Advancement of Science) (21.08.2020)
Published in Science (American Association for the Advancement of Science) (21.08.2020)
Get full text
Journal Article
Auranofin exerts broad-spectrum bactericidal activities by targeting thiol-redox homeostasis
Harbut, Michael B., Vilchèze, Catherine, Luo, Xiaozhou, Hensler, Mary E., Guo, Hui, Yang, Baiyuan, Chatterjee, Arnab K., Nizet, Victor, Jacobs, William R., Schultz, Peter G., Wang, Feng
Published in Proceedings of the National Academy of Sciences - PNAS (07.04.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (07.04.2015)
Get full text
Journal Article
The ReFRAME library as a comprehensive drug repurposing library and its application to the treatment of cryptosporidiosis
Janes, Jeff, Young, Megan E., Chen, Emily, Rogers, Nicole H., Burgstaller-Muehlbacher, Sebastian, Hughes, Laura D., Love, Melissa S., Hull, Mitchell V., Kuhen, Kelli L., Woods, Ashley K., Joseph, Sean B., Petrassi, H. Michael, McNamara, Case W., Tremblay, Matthew S., Su, Andrew I., Schultz, Peter G., Chatterjee, Arnab K.
Published in Proceedings of the National Academy of Sciences - PNAS (16.10.2018)
Published in Proceedings of the National Academy of Sciences - PNAS (16.10.2018)
Get full text
Journal Article
A high-throughput phenotypic screen identifies clofazimine as a potential treatment for cryptosporidiosis
Love, Melissa S, Beasley, Federico C, Jumani, Rajiv S, Wright, Timothy M, Chatterjee, Arnab K, Huston, Christopher D, Schultz, Peter G, McNamara, Case W
Published in PLoS neglected tropical diseases (03.02.2017)
Published in PLoS neglected tropical diseases (03.02.2017)
Get full text
Journal Article
Drug repurposing screens identify chemical entities for the development of COVID-19 interventions
Bakowski, Malina A., Beutler, Nathan, Wolff, Karen C., Kirkpatrick, Melanie G., Chen, Emily, Nguyen, Tu-Trinh H., Riva, Laura, Shaabani, Namir, Parren, Mara, Ricketts, James, Gupta, Anil K., Pan, Kastin, Kuo, Peiting, Fuller, MacKenzie, Garcia, Elijah, Teijaro, John R., Yang, Linlin, Sahoo, Debashis, Chi, Victor, Huang, Edward, Vargas, Natalia, Roberts, Amanda J., Das, Soumita, Ghosh, Pradipta, Woods, Ashley K., Joseph, Sean B., Hull, Mitchell V., Schultz, Peter G., Burton, Dennis R., Chatterjee, Arnab K., McNamara, Case W., Rogers, Thomas F.
Published in Nature communications (03.06.2021)
Published in Nature communications (03.06.2021)
Get full text
Journal Article
The combined treatment of Molnupiravir and Favipiravir results in a potentiation of antiviral efficacy in a SARS-CoV-2 hamster infection model
Abdelnabi, Rana, Foo, Caroline S., Kaptein, Suzanne J.F., Zhang, Xin, Do, Thuc Nguyen Dan, Langendries, Lana, Vangeel, Laura, Breuer, Judith, Pang, Juanita, Williams, Rachel, Vergote, Valentijn, Heylen, Elisabeth, Leyssen, Pieter, Dallmeier, Kai, Coelmont, Lotte, Chatterjee, Arnab K., Mols, Raf, Augustijns, Patrick, De Jonghe, Steven, Jochmans, Dirk, Weynand, Birgit, Neyts, Johan
Published in EBioMedicine (01.10.2021)
Published in EBioMedicine (01.10.2021)
Get full text
Journal Article
Antiviral drug screen identifies DNA-damage response inhibitor as potent blocker of SARS-CoV-2 replication
Garcia, Gustavo, Sharma, Arun, Ramaiah, Arunachalam, Sen, Chandani, Purkayastha, Arunima, Kohn, Donald B., Parcells, Mark S., Beck, Sebastian, Kim, Heeyoung, Bakowski, Malina A., Kirkpatrick, Melanie G., Riva, Laura, Wolff, Karen C., Han, Brandon, Yuen, Constance, Ulmert, David, Purbey, Prabhat K., Scumpia, Philip, Beutler, Nathan, Rogers, Thomas F., Chatterjee, Arnab K., Gabriel, Gülsah, Bartenschlager, Ralf, Gomperts, Brigitte, Svendsen, Clive N., Betz, Ulrich A.K., Damoiseaux, Robert D., Arumugaswami, Vaithilingaraja
Published in Cell reports (Cambridge) (06.04.2021)
Published in Cell reports (Cambridge) (06.04.2021)
Get full text
Journal Article
Neratinib protects pancreatic beta cells in diabetes
Ardestani, Amin, Li, Sijia, Annamalai, Karthika, Lupse, Blaz, Geravandi, Shirin, Dobrowolski, Aleksandra, Yu, Shan, Zhu, Siying, Baguley, Tyler D., Surakattula, Murali, Oetjen, Janina, Hauberg-Lotte, Lena, Herranz, Raquel, Awal, Sushil, Altenhofen, Delsi, Nguyen-Tran, Van, Joseph, Sean, Schultz, Peter G., Chatterjee, Arnab K., Rogers, Nikki, Tremblay, Matthew S., Shen, Weijun, Maedler, Kathrin
Published in Nature communications (01.11.2019)
Published in Nature communications (01.11.2019)
Get full text
Journal Article
Identification of a small molecule with activity against drug-resistant and persistent tuberculosis
Wang, Feng, Sambandan, Dhinakaran, Halder, Rajkumar, Wang, Jianing, Batt, Sarah M, Weinrick, Brian, Ahmad, Insha, Yang, Pengyu, Zhang, Yong, Kim, John, Hassani, Morad, Huszar, Stanislav, Trefzer, Claudia, Ma, Zhenkun, Kaneko, Takushi, Mdluli, Khisi E, Franzblau, Scott, Chatterjee, Arnab K, Johnsson, Kai, Johnson, Kai, Mikusova, Katarina, Besra, Gurdyal S, Fütterer, Klaus, Robbins, Scott H, Barnes, S Whitney, Walker, John R, Jacobs, Jr, William R, Schultz, Peter G
Published in Proceedings of the National Academy of Sciences - PNAS (02.07.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (02.07.2013)
Get full text
Journal Article
Bicyclic azetidines target acute and chronic stages of Toxoplasma gondii by inhibiting parasite phenylalanyl t-RNA synthetase
Radke, Joshua B., Melillo, Bruno, Mittal, Payal, Sharma, Manmohan, Sharma, Amit, Fu, Yong, Uddin, Taher, Gonse, Arthur, Comer, Eamon, Schreiber, Stuart L., Gupta, Anil K., Chatterjee, Arnab K., Sibley, L. David
Published in Nature communications (24.01.2022)
Published in Nature communications (24.01.2022)
Get full text
Journal Article
Drug repurposing screen identifies lonafarnib as respiratory syncytial virus fusion protein inhibitor
Sake, Svenja M., Zhang, Xiaoyu, Rajak, Manoj Kumar, Urbanek-Quaing, Melanie, Carpentier, Arnaud, Gunesch, Antonia P., Grethe, Christina, Matthaei, Alina, Rückert, Jessica, Galloux, Marie, Larcher, Thibaut, Le Goffic, Ronan, Hontonnou, Fortune, Chatterjee, Arnab K., Johnson, Kristen, Morwood, Kaycie, Rox, Katharina, Elgaher, Walid A. M., Huang, Jiabin, Wetzke, Martin, Hansen, Gesine, Fischer, Nicole, Eléouët, Jean-Francois, Rameix-Welti, Marie-Anne, Hirsch, Anna K. H., Herold, Elisabeth, Empting, Martin, Lauber, Chris, Schulz, Thomas F., Krey, Thomas, Haid, Sibylle, Pietschmann, Thomas
Published in Nature communications (08.02.2024)
Published in Nature communications (08.02.2024)
Get full text
Journal Article
Design, Synthesis, and Biological Evaluation of Indole-2-carboxamides: A Promising Class of Antituberculosis Agents
Kondreddi, Ravinder Reddy, Jiricek, Jan, Rao, Srinivasa P. S, Lakshminarayana, Suresh B, Camacho, Luis R, Rao, Ranga, Herve, Maxime, Bifani, Pablo, Ma, Ngai Ling, Kuhen, Kelli, Goh, Anne, Chatterjee, Arnab K, Dick, Thomas, Diagana, Thierry T, Manjunatha, Ujjini H, Smith, Paul W
Published in Journal of medicinal chemistry (14.11.2013)
Published in Journal of medicinal chemistry (14.11.2013)
Get full text
Journal Article
Small molecule inhibitors of trans-translation have broad-spectrum antibiotic activity
Ramadoss, Nitya S., Alumasa, John N., Cheng, Lin, Wang, Yu, Li, Sharon, Chambers, Benjamin S., Chang, Hoon, Chatterjee, Arnab K., Brinker, Achim, Engels, Ingo H., Keiler, Kenneth C.
Published in Proceedings of the National Academy of Sciences - PNAS (18.06.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (18.06.2013)
Get full text
Journal Article
Mutations in the P‑Type Cation-Transporter ATPase 4, PfATP4, Mediate Resistance to Both Aminopyrazole and Spiroindolone Antimalarials
Flannery, Erika L, McNamara, Case W, Kim, Sang Wan, Kato, Tomoyo Sakata, Li, Fengwu, Teng, Christine H, Gagaring, Kerstin, Manary, Micah J, Barboa, Rachel, Meister, Stephan, Kuhen, Kelli, Vinetz, Joseph M, Chatterjee, Arnab K, Winzeler, Elizabeth A
Published in ACS chemical biology (20.02.2015)
Published in ACS chemical biology (20.02.2015)
Get full text
Journal Article
Utilizing Chemical Genomics to Identify Cytochrome b as a Novel Drug Target for Chagas Disease
Khare, Shilpi, Roach, Steven L, Barnes, S Whitney, Hoepfner, Dominic, Walker, John R, Chatterjee, Arnab K, Neitz, R Jeffrey, Arkin, Michelle R, McNamara, Case W, Ballard, Jaime, Lai, Yin, Fu, Yue, Molteni, Valentina, Yeh, Vince, McKerrow, James H, Glynne, Richard J, Supek, Frantisek
Published in PLoS pathogens (01.07.2015)
Published in PLoS pathogens (01.07.2015)
Get full text
Journal Article
Chemical Inhibition of ENL/AF9 YEATS Domains in Acute Leukemia
Garnar-Wortzel, Leopold, Bishop, Timothy R, Kitamura, Seiya, Milosevich, Natalia, Asiaban, Joshua N, Zhang, Xiaoyu, Zheng, Qinheng, Chen, Emily, Ramos, Anissa R, Ackerman, Christopher J, Hampton, Eric N, Chatterjee, Arnab K, Young, Travis S, Hull, Mitchell V, Sharpless, K. Barry, Cravatt, Benjamin F, Wolan, Dennis W, Erb, Michael A
Published in ACS central science (26.05.2021)
Published in ACS central science (26.05.2021)
Get full text
Journal Article
KAI407, a Potent Non-8-Aminoquinoline Compound That Kills Plasmodium cynomolgi Early Dormant Liver Stage Parasites In Vitro
ZEEMAN, Anne-Marie, VAN AMSTERDAM, Sandra M, SAUERWEIN, Robert, GAGARING, Kerstin, BORBOA, Rachel, ZHONG CHEN, KUHEN, Kelli, GLYNNE, Richard J, CHATTERJEE, Arnab K, NAGLE, Advait, ROLAND, Jason, WINZELER, Elizabeth A, MCNAMARA, Case W, LEROY, Didier, CAMPO, Brice, DIAGANA, Thierry T, YEUNG, Bryan K. S, THOMAS, Alan W, KOCKEN, Clemens H. M, VOORBERG-VAN DER WEL, Annemarie, KLOOSTER, Els J, VAN DEN BERG, Alexander, REMARQUE, Edmond J, PLOUFFE, David M, VAN GEMERT, Geert-Jan, LUTY, Adrian
Published in Antimicrobial Agents and Chemotherapy (01.03.2014)
Published in Antimicrobial Agents and Chemotherapy (01.03.2014)
Get full text
Journal Article