Codon-specific translation reprogramming promotes resistance to targeted therapy
Rapino, Francesca, Delaunay, Sylvain, Rambow, Florian, Zhou, Zhaoli, Tharun, Lars, De Tullio, Pascal, Sin, Olga, Shostak, Kateryna, Schmitz, Sebastian, Piepers, Jolanda, Ghesquière, Bart, Karim, Latifa, Charloteaux, Benoit, Jamart, Diane, Florin, Alexandra, Lambert, Charles, Rorive, Andrée, Jerusalem, Guy, Leucci, Eleonora, Dewaele, Michael, Vooijs, Marc, Leidel, Sebastian A., Georges, Michel, Voz, Marianne, Peers, Bernard, Büttner, Reinhard, Marine, Jean-Christophe, Chariot, Alain, Close, Pierre
Published in Nature (London) (01.06.2018)
Published in Nature (London) (01.06.2018)
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A reference map of the human binary protein interactome
Luck, Katja, Kim, Dae-Kyum, Lambourne, Luke, Spirohn, Kerstin, Begg, Bridget E., Bian, Wenting, Brignall, Ruth, Cafarelli, Tiziana, Campos-Laborie, Francisco J., Charloteaux, Benoit, Choi, Dongsic, Coté, Atina G., Daley, Meaghan, Deimling, Steven, Desbuleux, Alice, Dricot, Amélie, Gebbia, Marinella, Hardy, Madeleine F., Kishore, Nishka, Knapp, Jennifer J., Kovács, István A., Lemmens, Irma, Mee, Miles W., Mellor, Joseph C., Pollis, Carl, Pons, Carles, Richardson, Aaron D., Schlabach, Sadie, Teeking, Bridget, Yadav, Anupama, Babor, Mariana, Balcha, Dawit, Basha, Omer, Bowman-Colin, Christian, Chin, Suet-Feung, Choi, Soon Gang, Colabella, Claudia, Coppin, Georges, D’Amata, Cassandra, De Ridder, David, De Rouck, Steffi, Duran-Frigola, Miquel, Ennajdaoui, Hanane, Goebels, Florian, Goehring, Liana, Gopal, Anjali, Haddad, Ghazal, Hatchi, Elodie, Helmy, Mohamed, Jacob, Yves, Kassa, Yoseph, Landini, Serena, Li, Roujia, van Lieshout, Natascha, MacWilliams, Andrew, Markey, Dylan, Paulson, Joseph N., Rangarajan, Sudharshan, Rasla, John, Rayhan, Ashyad, Rolland, Thomas, San-Miguel, Adriana, Shen, Yun, Sheykhkarimli, Dayag, Sheynkman, Gloria M., Simonovsky, Eyal, Taşan, Murat, Tejeda, Alexander, Tropepe, Vincent, Twizere, Jean-Claude, Wang, Yang, Weatheritt, Robert J., Weile, Jochen, Xia, Yu, Yang, Xinping, Yeger-Lotem, Esti, Zhong, Quan, Aloy, Patrick, Bader, Gary D., De Las Rivas, Javier, Gaudet, Suzanne, Hao, Tong, Rak, Janusz, Tavernier, Jan, Hill, David E., Vidal, Marc, Roth, Frederick P., Calderwood, Michael A.
Published in Nature (London) (01.04.2020)
Published in Nature (London) (01.04.2020)
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A Proteome-Scale Map of the Human Interactome Network
Rolland, Thomas, Taşan, Murat, Charloteaux, Benoit, Pevzner, Samuel J., Zhong, Quan, Sahni, Nidhi, Yi, Song, Lemmens, Irma, Fontanillo, Celia, Mosca, Roberto, Kamburov, Atanas, Ghiassian, Susan D., Yang, Xinping, Ghamsari, Lila, Balcha, Dawit, Begg, Bridget E., Braun, Pascal, Brehme, Marc, Broly, Martin P., Carvunis, Anne-Ruxandra, Convery-Zupan, Dan, Corominas, Roser, Coulombe-Huntington, Jasmin, Dann, Elizabeth, Dreze, Matija, Dricot, Amélie, Fan, Changyu, Franzosa, Eric, Gebreab, Fana, Gutierrez, Bryan J., Hardy, Madeleine F., Jin, Mike, Kang, Shuli, Kiros, Ruth, Lin, Guan Ning, Luck, Katja, MacWilliams, Andrew, Menche, Jörg, Murray, Ryan R., Palagi, Alexandre, Poulin, Matthew M., Rambout, Xavier, Rasla, John, Reichert, Patrick, Romero, Viviana, Ruyssinck, Elien, Sahalie, Julie M., Scholz, Annemarie, Shah, Akash A., Sharma, Amitabh, Shen, Yun, Spirohn, Kerstin, Tam, Stanley, Tejeda, Alexander O., Wanamaker, Shelly A., Twizere, Jean-Claude, Vega, Kerwin, Walsh, Jennifer, Cusick, Michael E., Xia, Yu, Barabási, Albert-László, Iakoucheva, Lilia M., Aloy, Patrick, De Las Rivas, Javier, Tavernier, Jan, Calderwood, Michael A., Hill, David E., Hao, Tong, Roth, Frederick P., Vidal, Marc
Published in Cell (20.11.2014)
Published in Cell (20.11.2014)
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Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing
Yang, Xinping, Coulombe-Huntington, Jasmin, Kang, Shuli, Sheynkman, Gloria M., Hao, Tong, Richardson, Aaron, Sun, Song, Yang, Fan, Shen, Yun A., Murray, Ryan R., Spirohn, Kerstin, Begg, Bridget E., Duran-Frigola, Miquel, MacWilliams, Andrew, Pevzner, Samuel J., Zhong, Quan, Wanamaker, Shelly A., Tam, Stanley, Ghamsari, Lila, Sahni, Nidhi, Yi, Song, Rodriguez, Maria D., Balcha, Dawit, Tan, Guihong, Costanzo, Michael, Andrews, Brenda, Boone, Charles, Zhou, Xianghong J., Salehi-Ashtiani, Kourosh, Charloteaux, Benoit, Chen, Alyce A., Calderwood, Michael A., Aloy, Patrick, Roth, Frederick P., Hill, David E., Iakoucheva, Lilia M., Xia, Yu, Vidal, Marc
Published in Cell (11.02.2016)
Published in Cell (11.02.2016)
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Single-cell RNA sequencing of human liver reveals hepatic stellate cell heterogeneity
Payen, Valéry L., Lavergne, Arnaud, Alevra Sarika, Niki, Colonval, Megan, Karim, Latifa, Deckers, Manon, Najimi, Mustapha, Coppieters, Wouter, Charloteaux, Benoît, Sokal, Etienne M., El Taghdouini, Adil
Published in JHEP reports (01.06.2021)
Published in JHEP reports (01.06.2021)
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The X-linked trichothiodystrophy-causing gene RNF113A links the spliceosome to cell survival upon DNA damage
Shostak, Kateryna, Jiang, Zheshen, Charloteaux, Benoit, Mayer, Alice, Habraken, Yvette, Tharun, Lars, Klein, Sebastian, Xu, Xinyi, Duong, Hong Quan, Vislovukh, Andrii, Close, Pierre, Florin, Alexandra, Rambow, Florian, Marine, Jean-Christophe, Büttner, Reinhard, Chariot, Alain
Published in Nature communications (09.03.2020)
Published in Nature communications (09.03.2020)
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IBD risk loci are enriched in multigenic regulatory modules encompassing putative causative genes
Momozawa, Yukihide, Dmitrieva, Julia, Théâtre, Emilie, Deffontaine, Valérie, Rahmouni, Souad, Charloteaux, Benoît, Crins, François, Docampo, Elisa, Elansary, Mahmoud, Gori, Ann-Stephan, Lecut, Christelle, Mariman, Rob, Mni, Myriam, Oury, Cécile, Altukhov, Ilya, Alexeev, Dmitry, Aulchenko, Yuri, Amininejad, Leila, Bouma, Gerd, Hoentjen, Frank, Löwenberg, Mark, Oldenburg, Bas, Pierik, Marieke J., vander Meulen-de Jong, Andrea E., Janneke van der Woude, C., Visschedijk, Marijn C., Lathrop, Mark, Hugot, Jean-Pierre, Weersma, Rinse K., De Vos, Martine, Franchimont, Denis, Vermeire, Severine, Kubo, Michiaki, Louis, Edouard, Georges, Michel
Published in Nature communications (21.06.2018)
Published in Nature communications (21.06.2018)
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Edgetic perturbation models of human inherited disorders
Hill, David E, Klitgord, Niels, Yan, Han, Cusick, Michael E, Heuze, Fabien, Lin, Chenwei, Vidal, Marc, Venkatesan, Kavitha, Zhong, Quan, Mou, Danny, Simonis, Nicolas, Swearingen, Venus, Yildirim, Muhammed A, Szeto, David, Fan, Changyu, Li, Qian-Ru, Yu, Haiyuan, Dricot, Amélie, Brasseur, Robert, Hao, Tong, Charloteaux, Benoit, Dupuy, Denis, Milstein, Stuart, Tam, Stanley
Published in Molecular systems biology (2009)
Published in Molecular systems biology (2009)
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Methylglyoxal, a glycolysis metabolite, triggers metastasis through MEK/ERK/SMAD1 pathway activation in breast cancer
Nokin, Marie-Julie, Bellier, Justine, Durieux, Florence, Peulen, Olivier, Rademaker, Gilles, Gabriel, Maude, Monseur, Christine, Charloteaux, Benoit, Verbeke, Lieven, van Laere, Steven, Roncarati, Patrick, Herfs, Michael, Lambert, Charles, Scheijen, Jean, Schalkwijk, Casper, Colige, Alain, Caers, Jo, Delvenne, Philippe, Turtoi, Andrei, Castronovo, Vincent, Bellahcène, Akeila
Published in Breast cancer research : BCR (23.01.2019)
Published in Breast cancer research : BCR (23.01.2019)
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Rapid Whole Genome Sequencing Diagnoses and Guides Treatment in Critically Ill Children in Belgium in Less than 40 Hours
Lumaka, Aimé, Fasquelle, Corinne, Debray, Francois-Guillaume, Alkan, Serpil, Jacquinet, Adeline, Harvengt, Julie, Boemer, François, Mulder, André, Vaessen, Sandrine, Viellevoye, Renaud, Palmeira, Leonor, Charloteaux, Benoit, Brysse, Anne, Bulk, Saskia, Rigo, Vincent, Bours, Vincent
Published in International journal of molecular sciences (16.02.2023)
Published in International journal of molecular sciences (16.02.2023)
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The HTLV-1 viral oncoproteins Tax and HBZ reprogram the cellular mRNA splicing landscape
Vandermeulen, Charlotte, O'Grady, Tina, Wayet, Jerome, Galvan, Bartimee, Maseko, Sibusiso, Cherkaoui, Majid, Desbuleux, Alice, Coppin, Georges, Olivet, Julien, Ben Ameur, Lamya, Kataoka, Keisuke, Ogawa, Seishi, Hermine, Olivier, Marcais, Ambroise, Thiry, Marc, Mortreux, Franck, Calderwood, Michael A, Van Weyenbergh, Johan, Peloponese, Jean-Marie, Charloteaux, Benoit, Van den Broeke, Anne, Hill, David E, Vidal, Marc, Dequiedt, Franck, Twizere, Jean-Claude
Published in PLoS pathogens (20.09.2021)
Published in PLoS pathogens (20.09.2021)
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Transcriptome-wide analysis of natural antisense transcripts shows their potential role in breast cancer
Wenric, Stephane, ElGuendi, Sonia, Caberg, Jean-Hubert, Bezzaou, Warda, Fasquelle, Corinne, Charloteaux, Benoit, Karim, Latifa, Hennuy, Benoit, Frères, Pierre, Collignon, Joëlle, Boukerroucha, Meriem, Schroeder, Hélène, Olivier, Fabrice, Jossa, Véronique, Jerusalem, Guy, Josse, Claire, Bours, Vincent
Published in Scientific reports (12.12.2017)
Published in Scientific reports (12.12.2017)
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Analysis of Genes Associated With Monogenic Primary Immunodeficiency Identifies Rare Variants in XIAP in Patients With Crohn’s Disease
Amininejad, Leila, Charloteaux, Benoit, Theatre, Emilie, Liefferinckx, Claire, Dmitrieva, Julia, Hayard, Pierre, Muls, Vincianne, Maisin, Jean-Marc, Schapira, Michael, Ghislain, Jean-Michel, Closset, Pierre, Talib, Mehdi, Abramowicz, Marc, Momozawa, Yukihide, Deffontaine, Valerie, Crins, François, Mni, Myriam, Karim, Latifa, Cambisano, Nadine, Ornemese, Sandra, Zucchi, Alessandro, Minsart, Charlotte, Deviere, Jacques, Hugot, Jean-Pierre, De vos, Martine, Louis, Edouard, Vermeire, Severine, Van Gossum, Andre, Coppieters, Wouter, Twizere, Jean-Claude, Georges, Michel, Franchimont, Denis
Published in Gastroenterology (New York, N.Y. 1943) (01.06.2018)
Published in Gastroenterology (New York, N.Y. 1943) (01.06.2018)
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An inter‐species protein–protein interaction network across vast evolutionary distance
Zhong, Quan, Pevzner, Samuel J, Hao, Tong, Wang, Yang, Mosca, Roberto, Menche, Jörg, Taipale, Mikko, Taşan, Murat, Fan, Changyu, Yang, Xinping, Haley, Patrick, Murray, Ryan R, Mer, Flora, Gebreab, Fana, Tam, Stanley, MacWilliams, Andrew, Dricot, Amélie, Reichert, Patrick, Santhanam, Balaji, Ghamsari, Lila, Calderwood, Michael A, Rolland, Thomas, Charloteaux, Benoit, Lindquist, Susan, Barabási, Albert‐László, Hill, David E, Aloy, Patrick, Cusick, Michael E, Xia, Yu, Roth, Frederick P, Vidal, Marc
Published in Molecular systems biology (01.04.2016)
Published in Molecular systems biology (01.04.2016)
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'Edgetic' perturbation of a C. elegans BCL2 ortholog
Vidal, Marc, Dreze, Matija, Charloteaux, Benoit, Milstein, Stuart, Vidalain, Pierre-Olivier, Yildirim, Muhammed A, Zhong, Quan, Svrzikapa, Nenad, Romero, Viviana, Laloux, Géraldine, Brasseur, Robert, Vandenhaute, Jean, Boxem, Mike, Cusick, Michael E, Hill, David E
Published in Nature methods (01.11.2009)
Published in Nature methods (01.11.2009)
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An efficient algorithm to perform multiple testing in epistasis screening
Van Lishout, François, Mahachie John, Jestinah M, Gusareva, Elena S, Urrea, Victor, Cleynen, Isabelle, Théâtre, Emilie, Charloteaux, Benoît, Calle, Malu Luz, Wehenkel, Louis, Van Steen, Kristel
Published in BMC bioinformatics (24.04.2013)
Published in BMC bioinformatics (24.04.2013)
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Variability and action mechanism of a family of anticomplement proteins in Ixodes ricinus
Couvreur, Bernard, Beaufays, Jérôme, Charon, Cédric, Lahaye, Kathia, Gensale, François, Denis, Valérie, Charloteaux, Benoît, Decrem, Yves, Prévôt, Pierre-Paul, Brossard, Michel, Vanhamme, Luc, Godfroid, Edmond
Published in PloS one (02.01.2008)
Published in PloS one (02.01.2008)
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Characterization of a novel aphid prenyltransferase displaying dual geranyl/farnesyl diphosphate synthase activity
Vandermoten, Sophie, Charloteaux, Benoit, Santini, Sébastien, Sen, Stephanie E., Béliveau, Catherine, Vandenbol, Micheline, Francis, Frédéric, Brasseur, Robert, Cusson, Michel, Haubruge, Éric
Published in FEBS letters (11.06.2008)
Published in FEBS letters (11.06.2008)
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Structural features conferring dual Geranyl/Farnesyl diphosphate synthase activity to an aphid prenyltransferase
Vandermoten, Sophie, Santini, Sébastien, Haubruge, Éric, Heuze, Fabien, Francis, Frédéric, Brasseur, Robert, Cusson, Michel, Charloteaux, Benoit
Published in Insect biochemistry and molecular biology (01.10.2009)
Published in Insect biochemistry and molecular biology (01.10.2009)
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PepLook: An innovative in silico tool for determination of structure, polymorphism and stability of peptides
Thomas, Annick, Deshayes, Sebastien, Decaffmeyer, Marc, Van Eyck, Marie-Helene, Charloteaux, Benoît, Brasseur, Robert, Escher, E, Lubell, W. D
Published in Advances in experimental medicine and biology (2009)
Published in Advances in experimental medicine and biology (2009)
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