Sacituzumab Govitecan (IMMU-132), an Anti-Trop-2/SN-38 Antibody–Drug Conjugate: Characterization and Efficacy in Pancreatic, Gastric, and Other Cancers
Cardillo, Thomas M., Govindan, Serengulam V., Sharkey, Robert M., Trisal, Preeti, Arrojo, Roberto, Liu, Donglin, Rossi, Edmund A., Chang, Chien-Hsing, Goldenberg, David M.
Published in Bioconjugate chemistry (20.05.2015)
Published in Bioconjugate chemistry (20.05.2015)
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Journal Article
Combination Therapy with Bispecific Antibodies and PD-1 Blockade Enhances the Antitumor Potency of T Cells
Chang, Chien-Hsing, Wang, Yang, Li, Rongxiu, Rossi, Diane L, Liu, Donglin, Rossi, Edmund A, Cardillo, Thomas M, Goldenberg, David M
Published in Cancer research (Chicago, Ill.) (01.10.2017)
Published in Cancer research (Chicago, Ill.) (01.10.2017)
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Journal Article
Selective and Concentrated Accretion of SN-38 with a CEACAM5-Targeting Antibody-Drug Conjugate (ADC), Labetuzumab Govitecan (IMMU-130)
Sharkey, Robert M, Govindan, Serengulam V, Cardillo, Thomas M, Donnell, Jennifer, Xia, Jing, Rossi, Edmund A, Chang, Chien-Hsing, Goldenberg, David M
Published in Molecular cancer therapeutics (01.01.2018)
Published in Molecular cancer therapeutics (01.01.2018)
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Journal Article
CD74: A New Candidate Target for the Immunotherapy of B-Cell Neoplasms
STEIN, Rhona, MATTES, M. Jules, CARDILLO, Thomas M, HANSEN, Hans J, CHANG, Chien-Hsing, BURTON, Jack, GOVINDAN, Serengulam, GOLDENBERG, David M
Published in Clinical cancer research (15.09.2007)
Published in Clinical cancer research (15.09.2007)
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Journal Article
Conference Proceeding
IMMU-140, a Novel SN-38 Antibody-Drug Conjugate Targeting HLA-DR, Mediates Dual Cytotoxic Effects in Hematologic Cancers and Malignant Melanoma
Cardillo, Thomas M, Govindan, Serengulam V, Zalath, Maria B, Rossi, Diane L, Wang, Yang, Chang, Chien-Hsing, Goldenberg, David M
Published in Molecular cancer therapeutics (01.01.2018)
Published in Molecular cancer therapeutics (01.01.2018)
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Journal Article
Horizontal transmission and retention of malignancy, as well as functional human genes, after spontaneous fusion of human glioblastoma and hamster host cells in vivo
Goldenberg, David M., Zagzag, David, Heselmeyer-Haddad, Kerstin M., Berroa Garcia, Lissa Y., Ried, Thomas, Loo, Meiyu, Chang, Chien-Hsing, Gold, David V.
Published in International journal of cancer (01.07.2012)
Published in International journal of cancer (01.07.2012)
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Journal Article
In-vivo fusion of human cancer and hamster stromal cells permanently transduces and transcribes human DNA
Goldenberg, David M, Rooney, Robert J, Loo, Meiyu, Liu, Donglin, Chang, Chien-Hsing
Published in PloS one (26.09.2014)
Published in PloS one (26.09.2014)
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Journal Article
Properties and structure-function relationships of veltuzumab (hA20), a humanized anti-CD20 monoclonal antibody
Goldenberg, David M., Rossi, Edmund A., Stein, Rhona, Cardillo, Thomas M., Czuczman, Myron S., Hernandez-Ilizaliturri, Francisco J., Hansen, Hans J., Chang, Chien-Hsing
Published in Blood (29.01.2009)
Published in Blood (29.01.2009)
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Journal Article
Stably Tethered Multifunctional Structures of Defined Composition Made by the Dock and Lock Method for Use in Cancer Targeting
Rossi, Edmund A., Goldenberg, David M., Cardillo, Thomas M., McBride, William J., Sharkey, Robert M., Chang, Chien-Hsing
Published in Proceedings of the National Academy of Sciences - PNAS (02.05.2006)
Published in Proceedings of the National Academy of Sciences - PNAS (02.05.2006)
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Journal Article
Horizontal transmission of malignancy: in-vivo fusion of human lymphomas with hamster stroma produces tumors retaining human genes and lymphoid pathology
Goldenberg, David M, Gold, David V, Loo, Meiyu, Liu, Donglin, Chang, Chien-Hsing, Jaffe, Elaine S
Published in PloS one (06.02.2013)
Published in PloS one (06.02.2013)
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Journal Article
Signal amplification in molecular imaging by pretargeting a multivalent, bispecific antibody
Goldenberg, David M, Sharkey, Robert M, Cardillo, Thomas M, Rossi, Edmund A, Chang, Chien-Hsing, Karacay, Habibe, McBride, William J, Hansen, Hans J, Horak, Ivan D
Published in Nature medicine (01.11.2005)
Published in Nature medicine (01.11.2005)
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Journal Article
Recombinant Bispecific Monoclonal Antibodies Prepared by the Dock-and-Lock Strategy for Pretargeted Radioimmunotherapy
Sharkey, Robert M., PhD, Rossi, Edmund A., PhD, McBride, William J., PhD, Chang, Chien-Hsing, PhD, Goldenberg, David M., ScD, MD
Published in Seminars in nuclear medicine (01.05.2010)
Published in Seminars in nuclear medicine (01.05.2010)
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Journal Article
The Dock and Lock Method: A Novel Platform Technology for Building Multivalent, Multifunctional Structures of Defined Composition with Retained Bioactivity
CHANG, Chien-Hsing, ROSSI, Edmund A, GOLDENBERG, David M
Published in Clinical cancer research (15.09.2007)
Published in Clinical cancer research (15.09.2007)
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Journal Article
Conference Proceeding
Survival Improvement in Patients With Medullary Thyroid Carcinoma Who Undergo Pretargeted Anti–Carcinoembryonic-Antigen Radioimmunotherapy: A Collaborative Study With the French Endocrine Tumor Group
CHATAL, Jean-Francois, CAMPION, Loïc, BARBET, Jacques, KRAEBER-BODERE, Francoise, BARDET, Stephane, VUILLEZ, Jean-Philippe, CHARBONNEL, Bernard, ROHMER, Vincent, CHANG, Chien-Hsing, SHARKEY, Robert M, GOLDENBERG, David M
Published in Journal of clinical oncology (10.04.2006)
Published in Journal of clinical oncology (10.04.2006)
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Journal Article
A novel bispecific, trivalent antibody construct for targeting pancreatic carcinoma
Gold, David V, Goldenberg, David M, Karacay, Habibe, Rossi, Edmund A, Chang, Chien-Hsing, Cardillo, Thomas M, McBride, William J, Sharkey, Robert M
Published in Cancer research (Chicago, Ill.) (15.06.2008)
Published in Cancer research (Chicago, Ill.) (15.06.2008)
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Journal Article