Mechanism of MEK inhibition determines efficacy in mutant KRAS- versus BRAF-driven cancers
Hatzivassiliou, Georgia, Haling, Jacob R., Chen, Huifen, Song, Kyung, Price, Steve, Heald, Robert, Hewitt, Joanne F. M., Zak, Mark, Peck, Ariana, Orr, Christine, Merchant, Mark, Hoeflich, Klaus P., Chan, Jocelyn, Luoh, Shiuh-Ming, Anderson, Daniel J., Ludlam, Mary J. C., Wiesmann, Christian, Ultsch, Mark, Friedman, Lori S., Malek, Shiva, Belvin, Marcia
Published in Nature (London) (12.09.2013)
Published in Nature (London) (12.09.2013)
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Intermittent Administration of MEK Inhibitor GDC-0973 plus PI3K Inhibitor GDC-0941 Triggers Robust Apoptosis and Tumor Growth Inhibition
HOEFLICH, Klaus P, MERCHANT, Mark, ENGST, Stefan, JOHNSTON, Stuart, FRIEDMAN, Lori S, BELVIN, Marcia, ORR, Christine, CHAN, Jocelyn, DOUG DEN OTTER, BERRY, Leanne, KASMAN, Ian, KOEPPEN, Hartmut, RICE, Ken, YANG, Nai-Ying
Published in Cancer research (Chicago, Ill.) (2012)
Published in Cancer research (Chicago, Ill.) (2012)
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Journal Article
Real-world impact of dual anti-HER2 antibodies on cardiac function in patients with human epidermal growth factor receptor 2–positive metastatic breast cancer
Bao, Kelvin KH, Chan, Jeffrey CH, Chan, Jocelyn G., Sutanto, Leone, Cheung, Ka Man, Yiu, Harry HY
Published in Breast (Edinburgh) (01.02.2024)
Published in Breast (Edinburgh) (01.02.2024)
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Journal Article
Inflammasome activation links enteric Salmonella Typhimurium infection to a rapid, cytokine-dependent increase in intestinal mucin release
Han, Xiao, Allaire, Joannie M, Crowley, Shauna M, Chan, Jocelyn J, Lau, Kelly, Zhang, Conghao, Hirota, Simon A, Bergstrom, Kirk, Knodler, Leigh A, Vallance, Bruce A
Published in Gut microbes (31.12.2024)
Published in Gut microbes (31.12.2024)
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Journal Article
Combined MEK and ERK inhibition overcomes therapy-mediated pathway reactivation in RAS mutant tumors
Merchant, Mark, Moffat, John, Schaefer, Gabriele, Chan, Jocelyn, Wang, Xi, Orr, Christine, Cheng, Jason, Hunsaker, Thomas, Shao, Lily, Wang, Stephanie J, Wagle, Marie-Claire, Lin, Eva, Haverty, Peter M, Shahidi-Latham, Sheerin, Ngu, Hai, Solon, Margaret, Eastham-Anderson, Jeffrey, Koeppen, Hartmut, Huang, Shih-Min A, Schwarz, Jacob, Belvin, Marcia, Kirouac, Daniel, Junttila, Melissa R
Published in PloS one (05.10.2017)
Published in PloS one (05.10.2017)
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Journal Article
Monitoring travellers from Ebola-affected countries in New South Wales, Australia: what is the impact on travellers?
Chan, Jocelyn, Patel, Mahomed, Tobin, Sean, Sheppeard, Vicky
Published in BMC public health (24.01.2017)
Published in BMC public health (24.01.2017)
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Journal Article
Levels of pneumococcal conjugate vaccine coverage and indirect protection against invasive pneumococcal disease and pneumonia hospitalisations in Australia: An observational study
Chan, Jocelyn, Gidding, Heather F, Blyth, Christopher C, Fathima, Parveen, Jayasinghe, Sanjay, McIntyre, Peter B, Moore, Hannah C, Mulholland, Kim, Nguyen, Cattram D, Andrews, Ross, Russell, Fiona M
Published in PLoS medicine (03.08.2021)
Published in PLoS medicine (03.08.2021)
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Journal Article
An outbreak of psittacosis at a veterinary school demonstrating a novel source of infection
Chan, Jocelyn, Doyle, Bridget, Branley, James, Sheppeard, Vicky, Gabor, Melinda, Viney, Kerri, Quinn, Helen, Janover, Orly, McCready, Michael, Heller, Jane
Published in One health (01.06.2017)
Published in One health (01.06.2017)
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Journal Article
Role of P‑Glycoprotein on the Brain Penetration and Brain Pharmacodynamic Activity of the MEK Inhibitor Cobimetinib
Choo, Edna F, Ly, Justin, Chan, Jocelyn, Shahidi-Latham, Sheerin K, Messick, Kirsten, Plise, Emile, Quiason, Cristine M, Yang, Lulu
Published in Molecular pharmaceutics (03.11.2014)
Published in Molecular pharmaceutics (03.11.2014)
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Journal Article
Phosphoproteomic characterization of DNA damage response in melanoma cells following MEK/PI3K dual inhibition
Kirkpatrick, Donald S., Bustos, Daisy J., Dogan, Taner, Chan, Jocelyn, Phu, Lilian, Young, Amy, Friedman, Lori S., Belvin, Marcia, Song, Qinghua, Bakalarski, Corey E., Hoeflich, Klaus P.
Published in Proceedings of the National Academy of Sciences - PNAS (26.11.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (26.11.2013)
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Journal Article
Indium(III) chloride-catalyzed Mukaiyama–Michael addition: synthesis of 2,6- anti-tetrahydropyrans
Chua, Sin-Siu, Alni, Anita, Jocelyn Chan, Li-Ting, Yamane, Motoki, Loh, Teck-Peng
Published in Tetrahedron (08.07.2011)
Published in Tetrahedron (08.07.2011)
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Journal Article
Burden of Congenital Rubella Syndrome (CRS) in Bangladesh: Systematic Review of Existing Literature and Transmission Modelling of Seroprevalence Studies
Chan, Jocelyn, Wu, Yue, Wood, James, Muhit, Mohammad, Mahmood, Mohammed K, Karim, Tasneem, Moushumi, Farhana, Jones, Cheryl A, Snelling, Tom, Khandaker, Gulam
Published in Infectious disorders drug targets (2020)
Published in Infectious disorders drug targets (2020)
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Journal Article
Effectiveness of 13-valent pneumococcal conjugate vaccine against hypoxic pneumonia and hospitalisation in Eastern Highlands Province, Papua New Guinea: An observational cohort study
Blyth, Christopher C, Britton, Kathryn J, Nguyen, Cattram D, Sapura, Joycelyn, Kave, John, Nivio, Birunu, Chan, Jocelyn, Satzke, Catherine, Ford, Rebecca, Kirarock, Wendy, Lehmann, Deborah, Pomat, William, Russell, Fiona M
Published in The Lancet regional health. Western Pacific (01.05.2022)
Published in The Lancet regional health. Western Pacific (01.05.2022)
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Journal Article
Correction: Combined MEK and ERK inhibition overcomes therapy-mediated pathway reactivation in RAS mutant tumors
Merchant, Mark, Moffat, John, Schaefer, Gabriele, Chan, Jocelyn, Wang, Xi, Orr, Christine, Cheng, Jason, Hunsaker, Thomas, Shao, Lily, Wang, Stephanie J, Wagle, Marie-Claire, Lin, Eva, Haverty, Peter M, Shahidi-Latham, Sheerin, Ngu, Hai, Solon, Margaret, Eastham-Anderson, Jeffrey, Koeppen, Hartmut, Huang, Shih-Min A, Schwarz, Jacob, Belvin, Marcia, Kirouac, Daniel, Junttila, Melissa R
Published in PloS one (2018)
Published in PloS one (2018)
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Journal Article
Direct and indirect effects of 13-valent pneumococcal conjugate vaccine on pneumococcal carriage in children hospitalised with pneumonia from formal and informal settlements in Mongolia: an observational study
Chan, Jocelyn, Mungun, Tuya, Batsaixan, Purevsuren, Ulziibayar, Mukhchuluun, Suuri, Bujinlkham, Otgonbayar, Dashpagam, Luvsantseren, Dashtseren, Nguyen, Cattram D, Narangarel, Dorj, Dunne, Eileen M, Fox, Kimberley, Hinds, Jason, Nation, Monica L, Pell, Casey L, Mulholland, E Kim, Satzke, Catherine, von Mollendorf, Claire, Russell, Fiona M
Published in The Lancet regional health. Western Pacific (01.10.2021)
Published in The Lancet regional health. Western Pacific (01.10.2021)
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Journal Article
The effectiveness of the 13-valent pneumococcal conjugate vaccine against hypoxic pneumonia in children in Lao People's Democratic Republic: An observational hospital-based test-negative study
Weaver, Rupert, Nguyen, Cattram D., Chan, Jocelyn, Vilivong, Keoudomphone, Lai, Jana Y.R., Lim, Ruth, Satzke, Catherine, Vongsakid, Malisa, Newton, Paul N., Mulholland, Kim, Gray, Amy, Dubot-Pérès, Audrey, Dance, David A.B., Russell, Fiona M.
Published in The Lancet regional health. Western Pacific (01.09.2020)
Published in The Lancet regional health. Western Pacific (01.09.2020)
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Journal Article
Determining the pneumococcal conjugate vaccine coverage required for indirect protection within Asia and the Pacific: a prospective observational study
Chan, Jocelyn, Lai, Jana Y, von Mollendorf, Claire, Blyth, Christopher, Dance, David A B, Datta, Siddhartha, Dunne, Eileen M, Ford, Rebecca, Fox, Kimberley, Hinds, Jason, Vilivong, Keoudomphone, La Vincente, Sophie, Lehmann, Deborah, Moore, Kerryn A, Mungun, Tuya, Nation, Monica L, Newton, Paul N, Nguyen, Cattram D, Pomat, William, Xeuatvongsa, Anonh, Satzke, Catherine, Mulholland, E Kim, Russell, Fiona M
Published in The Lancet global health (01.03.2019)
Published in The Lancet global health (01.03.2019)
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Journal Article
High agreement between the new Mongolian electronic immunization register and written immunization records: a health centre based audit
Chan, Jocelyn, Mungun, Tuya, Dorj, Narangerel, Volody, Baigal, Chuluundorj, Uranjargal, Munkhbat, Enkhtuya, Danzan, Gerelmaa, Nguyen, Cattram D, La Vincente, Sophie, Russell, Fiona
Published in Western Pacific surveillance and response journal (01.07.2017)
Published in Western Pacific surveillance and response journal (01.07.2017)
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