Highly potent growth hormone secretagogues
Lu, Zhijian, Tata, James R., Cheng, Kang, Wei, Liente, Chan, Wanda W.-S., Butler, Bridget, Schleim, Klaus D., Jacks, Thomas M., Hickey, Gerard, Patchett, Arthur A.
Published in Bioorganic & medicinal chemistry letters (01.07.2007)
Published in Bioorganic & medicinal chemistry letters (01.07.2007)
Get full text
Journal Article
A Nonpeptidyl Growth Hormone Secretagogue
Smith, Roy G., Cheng, Kang, Schoen, William R., Pong, Sheng-Shung, Hickey, Gerard, Jacks, Tom, Butler, Bridget, Wanda W.-S. Chan, Chaung, Lee-Yuh P., Judith, Fred, Taylor, Joyce, Wyvratt, Matthew J., Fisher, Michael H.
Published in Science (American Association for the Advancement of Science) (11.06.1993)
Published in Science (American Association for the Advancement of Science) (11.06.1993)
Get full text
Journal Article
Rapid Identification of Subtype-Selective Agonists of the Somatostatin Receptor Through Combinatorial Chemistry
Rohrer, Susan P., Birzin, Elizabeth T., Mosley, Ralph T., Berk, Scott C., Hutchins, Steven M., Shen, Dong-Ming, Xiong, Yusheng, Hayes, Edward C., Parmar, Rupa M., Foor, Forrest, Mitra, Sudha W., Degrado, Sylvia J., Shu, Min, Klopp, John M., Cai, Sheng-Jian, Blake, Allan, Wanda W. S. Chan, Pasternak, Alex, Yang, Lihu, Patchett, Arthur A., Smith, Roy G., Chapman, Kevin T., Schaeffer, James M.
Published in Science (American Association for the Advancement of Science) (23.10.1998)
Published in Science (American Association for the Advancement of Science) (23.10.1998)
Get full text
Journal Article
Substituted bridged phenyl piperidines: orally active growth hormone secretagogues
Lu, Zhijian, Tata, James R., Cheng, Kang, Wei, Liente, Chan, Wanda W.-S., Butler, Bridget, Schleim, Klaus D., Jacks, Thomas M., Hickey, Gerard, Patchett, Arthur A.
Published in Bioorganic & medicinal chemistry letters (19.05.2003)
Published in Bioorganic & medicinal chemistry letters (19.05.2003)
Get full text
Journal Article
1-[2(R)-(2-Amino-2-methylpropionylamino)-3-(1H-indol-3-yl)propionyl]-3- benzylpiperidine-3(S)-carboxylic Acid Ethyl Ester (L-163,540): A Potent, Orally Bioavailable, and Short-Duration Growth Hormone Secretagogue
Yang, Lihu, Morriello, Greg, Patchett, Arthur A, Leung, Kwan, Jacks, Tom, Cheng, Kang, Schleim, Klaus D, Feeney, William, Chan, Wanda W.-S, Chiu, Shuet-Hing L, Smith, Roy G
Published in Journal of medicinal chemistry (02.07.1998)
Published in Journal of medicinal chemistry (02.07.1998)
Get full text
Journal Article
A Novel 3-Substituted Benzazepinone Growth Hormone Secretagogue (L-692,429)
Schoen, William R, Pisano, Judith M, Prendergast, Kristine, Wyvratt, Matthew J, Fisher, Michael H, Cheng, Kang, Chan, Wanda W.-S, Butler, Bridget, Smith, Roy G, Ball, Richard G
Published in Journal of medicinal chemistry (01.04.1994)
Published in Journal of medicinal chemistry (01.04.1994)
Get full text
Journal Article
A Potent, Orally Bioavailable Benzazepinone Growth Hormone Secretagogue
DeVita, Robert J, Bochis, Richard, Frontier, Alison J, Kotliar, Andrew, Fisher, Michael H, Schoen, William R, Wyvratt, Matthew J, Cheng, Kang, Chan, Wanda W.-S, Butler, Bridget, Jacks, Thomas M, Hickey, Gerard J, Schleim, Klaus D, Leung, Kwan, Chen, Zhesheng, Chiu, S.-H. Lee, Feeney, William P, Cunningham, Paul K, Smith, Roy G
Published in Journal of medicinal chemistry (07.05.1998)
Published in Journal of medicinal chemistry (07.05.1998)
Get full text
Journal Article
Synthesis and biological activities of spiroheterocyclic growth hormone secretagogues
Chen, Meng-Hsin, Pollard, Patrick P., Patchett, Arthur A., Cheng, Kang, Wei, Liente, Chan, Wanda W.-S., Butler, Bridget, Jacks, Thomas M., Smith, Roy G.
Published in Bioorganic & medicinal chemistry letters (03.05.1999)
Published in Bioorganic & medicinal chemistry letters (03.05.1999)
Get full text
Journal Article
Synthesis and biological activities of phenyl piperazine- based peptidomimetic growth hormone secretagogues
BARAKAT, K. J, KANG CHENG, NARGUND, R. P, CHAN, W. W.-S, BUTLER, B. S, JACKS, T. M, SCHLEIM, K. D, HORA, D. F, HICKEY, G. J, SMITH, R. G, PATCHETT, A. A
Published in Bioorganic & medicinal chemistry letters (02.06.1998)
Published in Bioorganic & medicinal chemistry letters (02.06.1998)
Get full text
Journal Article
Design and synthesis of potent macrocyclic benzolactam growth hormone secretagogues
DeVita, RJ, Frontier, AJ, Schoen, WR, Wyvratt, MJ, Fisher, MH, Cheng, K, Chan, WWS, Butler, BS, Smith, RG
Published in Helvetica chimica acta (30.06.1997)
Published in Helvetica chimica acta (30.06.1997)
Get more information
Journal Article
Heterocyclic analogs of the benzolactam nucleus of the non-peptidic growth hormone secretagogue L-692,429
DeVita, Robert J., Schoen, William R., Doldouras, George A., Fisher, Michael H., Wyvratt, Matthew J., Cheng, Kang, Chan, Wanda W.-S., Butler, Bridget S., Smith, Roy G.
Published in Bioorganic & medicinal chemistry letters (01.06.1995)
Published in Bioorganic & medicinal chemistry letters (01.06.1995)
Get full text
Journal Article
Benzolactam growth hormone secretagogues: Replacement of the C-3 amide bond in L-692,429
Ok, Hyun O, Szumiloski, John L, Doldouras, George A, Schoen, William R, Cheng, Kang, Chan, Wanda W.-S, Butler, Bridget S, Smith, Roy G, Fisher, Michael H, Wyvratt, Matthew J
Published in Bioorganic & medicinal chemistry letters (17.12.1996)
Published in Bioorganic & medicinal chemistry letters (17.12.1996)
Get full text
Journal Article
Substituted Bridged Phenyl Piperidines: Orally Active Growth Hormone Secretagogues
Lu, Zhijian, Tata, James R., Cheng, Kang, Wei, Liente, Chan, Wanda W.-S., Butler, Bridget, Schleim, Klaus D., Jacks, Thomas M., Hickey, Gerard, Patchett, Arthur A.
Published in ChemInform (23.09.2003)
Published in ChemInform (23.09.2003)
Get full text
Journal Article
Potent 3-spiropiperidine growth hormone secretagogues
Yang, Lihu, Morriello, Greg, Prendergast, Kristine, Cheng, Kang, Jacks, Tom, Chan, Wanda W.-S, Schleim, Klaus D, Smith, Roy G, Patchett, Arthur A
Published in Bioorganic & medicinal chemistry letters (06.01.1998)
Published in Bioorganic & medicinal chemistry letters (06.01.1998)
Get full text
Journal Article
Modeling directed design and biological evaluation of quinazolinones as non-peptidic growth hormone secretagogues
ZHIXIONG YE, YINGDUO GAO, LOCCO, L, PARMAR, R. M, CHAN, W. W.-S, SCHAEFFER, J. M, SMITH, R. G, PATCHETT, A. A, NARGUND, R. P, BAKSHI, R. K, CHEN, M.-H, ROHRER, S. P, FEIGHNER, S. D, PONG, S.-S, HOWARD, A. D, BLAKE, A, BIRZIN, E. T
Published in Bioorganic & medicinal chemistry letters (03.01.2000)
Published in Bioorganic & medicinal chemistry letters (03.01.2000)
Get full text
Journal Article
Analogs of the orally active growth hormone secretagogue L-162,752
Chen, Meng-Hsin, Steiner, Mark G., Patchett, Arthur A., Cheng, Kang, Wei, Liente, Chan, Wanda W.-S., Butler, Bridget, Jacks, Thomas M., Smith, Roy G.
Published in Bioorganic & medicinal chemistry letters (17.09.1996)
Published in Bioorganic & medicinal chemistry letters (17.09.1996)
Get full text
Journal Article
Acyclic structural variants of growth hormone secretagogue L-692,429
Lin, Peter, Pisano, Judith M., Schoen, William R., Kang Cheng, Chan, Wanda W.-S., Butler, Bridget S., Smith, Roy G., Fisher, Michael H., Wyvratt, Matthew J.
Published in Bioorganic & medicinal chemistry letters (15.11.1999)
Published in Bioorganic & medicinal chemistry letters (15.11.1999)
Get full text
Journal Article
Structure-activity relationships in the amino acid sidechain of L-692,429
Schoen, William R., Ok, Dong, DeVita, Robert J., Pisano, Judith M., Hodges, Paul, Cheng, Kang, Chan, Wanda W.-S., Butler, Bridget S., Smith, Roy G., Wyvratt, Matthew J., Fisher, Michael H.
Published in Bioorganic & medicinal chemistry letters (05.05.1994)
Published in Bioorganic & medicinal chemistry letters (05.05.1994)
Get full text
Journal Article
Synthesis and biological activities of camphor-based non-peptide growth hormone secretagogues
Nargund, Ravi P., Barakat, Khaled H., Cheng, Kang, Chan, Wanda W.-S., Butler, Bridget R., Smith, Roy G., Patchett, Arthur A.
Published in Bioorganic & medicinal chemistry letters (04.06.1996)
Published in Bioorganic & medicinal chemistry letters (04.06.1996)
Get full text
Journal Article