Insights from a 30-year journey: function, regulation and therapeutic modulation of PD1
Chamoto, Kenji, Yaguchi, Tomonori, Tajima, Masaki, Honjo, Tasuku
Published in Nature reviews. Immunology (01.10.2023)
Published in Nature reviews. Immunology (01.10.2023)
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Journal Article
Current issues and perspectives in PD-1 blockade cancer immunotherapy
Chamoto, Kenji, Hatae, Ryusuke, Honjo, Tasuku
Published in International journal of clinical oncology (01.05.2020)
Published in International journal of clinical oncology (01.05.2020)
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Journal Article
Cancer immunotherapies targeting the PD-1 signaling pathway
Iwai, Yoshiko, Hamanishi, Junzo, Chamoto, Kenji, Honjo, Tasuku
Published in Journal of biomedical science (04.04.2017)
Published in Journal of biomedical science (04.04.2017)
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Journal Article
Spermidine activates mitochondrial trifunctional protein and improves antitumor immunity in mice
Al-Habsi, Muna, Chamoto, Kenji, Matsumoto, Ken, Nomura, Norimichi, Zhang, Baihao, Sugiura, Yuki, Sonomura, Kazuhiro, Maharani, Aprilia, Nakajima, Yuka, Wu, Yibo, Nomura, Yayoi, Menzies, Rosemary, Tajima, Masaki, Kitaoka, Koji, Haku, Yasuharu, Delghandi, Sara, Yurimoto, Keiko, Matsuda, Fumihiko, Iwata, So, Ogura, Toshihiko, Fagarasan, Sidonia, Honjo, Tasuku
Published in Science (American Association for the Advancement of Science) (28.10.2022)
Published in Science (American Association for the Advancement of Science) (28.10.2022)
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Journal Article
Chemical induction of splice-neoantigens attenuates tumor growth in a preclinical model of colorectal cancer
Matsushima, Shingo, Ajiro, Masahiko, Iida, Kei, Chamoto, Kenji, Honjo, Tasuku, Hagiwara, Masatoshi
Published in Science translational medicine (30.11.2022)
Published in Science translational medicine (30.11.2022)
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Journal Article
PD-L1/L2 protein levels rapidly increase on monocytes via trogocytosis from tumor cells in classical Hodgkin lymphoma
Kawashima, Masaharu, Carreras, Joaquim, Higuchi, Hiroshi, Kotaki, Ryutaro, Hoshina, Takahiro, Okuyama, Kazuki, Suzuki, Naoto, Kakizaki, Masatoshi, Miyatake, Yuji, Ando, Kiyoshi, Nakayama, Masafumi, Umezu, Shinjiro, Horie, Ryouichi, Higuchi, Yuriko, Katagiri, Koko, Goyama, Susumu, Kitamura, Toshio, Chamoto, Kenji, Yano, Shingo, Nakamura, Naoya, Kotani, Ai
Published in Leukemia (01.09.2020)
Published in Leukemia (01.09.2020)
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Journal Article
PD-L1 is induced on the hepatocyte surface via CKLF-like MARVEL transmembrane domain-containing protein 6 up-regulation by the anti-HBV drug Entecavir
Yamamoto, Yuichiro, Kakizaki, Masatoshi, Shimizu, Takayuki, Carreras, Joaquim, Chiba, Tetsuhiro, Chamoto, Kenji, Kagawa, Tatehiro, Aoki, Taku, Nakamura, Naoya, Ando, Kiyoshi, Kotani, Ai
Published in International immunology (01.08.2020)
Published in International immunology (01.08.2020)
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Journal Article
Specific roles of each TCR hemichain in generating functional chain-centric TCR
Nakatsugawa, Munehide, Yamashita, Yuki, Ochi, Toshiki, Tanaka, Shinya, Chamoto, Kenji, Guo, Tingxi, Butler, Marcus O, Hirano, Naoto
Published in The Journal of immunology (1950) (01.04.2015)
Published in The Journal of immunology (1950) (01.04.2015)
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Journal Article
HLA-DP84Gly constitutively presents endogenous peptides generated by the class I antigen processing pathway
Yamashita, Yuki, Anczurowski, Mark, Nakatsugawa, Munehide, Tanaka, Makito, Kagoya, Yuki, Sinha, Ankit, Chamoto, Kenji, Ochi, Toshiki, Guo, Tingxi, Saso, Kayoko, Butler, Marcus O., Minden, Mark D., Kislinger, Thomas, Hirano, Naoto
Published in Nature communications (10.05.2017)
Published in Nature communications (10.05.2017)
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Journal Article
The combination of soluble forms of PD-1 and PD-L1 as a predictive marker of PD-1 blockade in patients with advanced cancers: a multicenter retrospective study
Kurosaki, Takashi, Chamoto, Kenji, Suzuki, Shinichiro, Kanemura, Hiroaki, Mitani, Seiichiro, Tanaka, Kaoru, Kawakami, Hisato, Kishimoto, Yo, Haku, Yasuharu, Ito, Katsuhiro, Sato, Toshiyuki, Suminaka, Chihiro, Yamaki, Mami, Chiba, Yasutaka, Yaguchi, Tomonori, Omori, Koichi, Kobayashi, Takashi, Nakagawa, Kazuhiko, Honjo, Tasuku, Hayashi, Hidetoshi
Published in Frontiers in immunology (11.12.2023)
Published in Frontiers in immunology (11.12.2023)
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Journal Article
The critical role of type‐1 innate and acquired immunity in tumor immunotherapy
Ikeda, Hiroaki, Chamoto, Kenji, Tsuji, Takemasa, Suzuki, Yoshinori, Wakita, Daiko, Takeshima, Tsuguhide, Nishimura, Takashi
Published in Cancer science (01.09.2004)
Published in Cancer science (01.09.2004)
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Journal Article
1α,25-Dihydroxyvitamin D3 and all-trans retinoic acid synergistically inhibit the differentiation and expansion of Th17 cells
Ikeda, Utako, Wakita, Daiko, Ohkuri, Takayuki, Chamoto, Kenji, Kitamura, Hidemitsu, Iwakura, Yoichiro, Nishimura, Takashi
Published in Immunology letters (30.11.2010)
Published in Immunology letters (30.11.2010)
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Journal Article
Anti‐OX40 monoclonal antibody therapy in combination with radiotherapy results in therapeutic antitumor immunity to murine lung cancer
Yokouchi, Hiroshi, Yamazaki, Koichi, Chamoto, Kenji, Kikuchi, Eiki, Shinagawa, Naofumi, Oizumi, Satoshi, Hommura, Fumihiro, Nishimura, Takashi, Nishimura, Masaharu
Published in Cancer science (01.02.2008)
Published in Cancer science (01.02.2008)
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Journal Article
Mouse and Human CD1d-Self-Lipid Complexes Are Recognized Differently by Murine Invariant Natural Killer T Cell Receptors
Guo, Tingxi, Chamoto, Kenji, Nakatsugawa, Munehide, Ochi, Toshiki, Yamashita, Yuki, Anczurowski, Mark, Butler, Marcus O, Hirano, Naoto
Published in PloS one (23.05.2016)
Published in PloS one (23.05.2016)
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Journal Article
Alveolar macrophage dynamics in murine lung regeneration
Chamoto, Kenji, Gibney, Barry C., Ackermann, Maximilian, Lee, Grace S., Lin, Miao, Konerding, Moritz A., Tsuda, Akira, Mentzer, Steven J.
Published in Journal of cellular physiology (01.09.2012)
Published in Journal of cellular physiology (01.09.2012)
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Journal Article
Key Residues at Third CDR3β Position Impact Structure and Antigen Recognition of Human Invariant NK TCRs
Chamoto, Kenji, Guo, Tingxi, Scally, Stephen W, Kagoya, Yuki, Anczurowski, Mark, Wang, Chung-Hsi, Rahman, Muhammed A, Saso, Kayoko, Butler, Marcus O, Chiu, Priscilla P L, Julien, Jean-Philippe, Hirano, Naoto
Published in The Journal of immunology (1950) (01.02.2017)
Published in The Journal of immunology (1950) (01.02.2017)
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Journal Article
Combination immunotherapy with radiation and CpG‐based tumor vaccination for the eradication of radio‐ and immuno‐resistant lung carcinoma cells
Chamoto, Kenji, Takeshima, Tsuguhide, Wakita, Daiko, Ohkuri, Takayuki, Ashino, Shigeru, Omatsu, Tokuhiko, Shirato, Hiroki, Kitamura, Hidemitsu, Togashi, Yuji, Nishimura, Takashi
Published in Cancer science (01.05.2009)
Published in Cancer science (01.05.2009)
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Journal Article