Comprehensive in vitro Proarrhythmia Assay (CiPA): Pending issues for successful validation and implementation
Cavero, Icilio, Guillon, Jean-Michel, Ballet, Veronique, Clements, Mike, Gerbeau, Jean-Frédéric, Holzgrefe, Henry
Published in Journal of pharmacological and toxicological methods (01.09.2016)
Published in Journal of pharmacological and toxicological methods (01.09.2016)
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Journal Article
Novel probabilistic method for precisely correcting the QT interval for heart rate in telemetered dogs and cynomolgus monkeys
Holzgrefe, Henry H., Cavero, Icilio, Gleason, Carol R., Warner, William A., Buchanan, Lewis V., Gill, Michael W., Burkett, Dennis E., Durham, Stephen K.
Published in Journal of pharmacological and toxicological methods (01.03.2007)
Published in Journal of pharmacological and toxicological methods (01.03.2007)
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Journal Article
QT interval prolongation by non-cardiovascular drugs: issues and solutions for novel drug development
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Book Review
Journal Article
Application of a probabilistic method for the determination of drug-induced QT prolongation in telemetered cynomolgus monkeys: Effects of moxifloxacin
Holzgrefe, Henry H., Cavero, Icilio, Buchanan, Lewis V., Gill, Michael W., Durham, Stephen K.
Published in Journal of pharmacological and toxicological methods (01.05.2007)
Published in Journal of pharmacological and toxicological methods (01.05.2007)
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Journal Article
CiPA: Ongoing testing, future qualification procedures, and pending issues
Cavero, Icilio, Holzgrefe, Henry
Published in Journal of pharmacological and toxicological methods (01.11.2015)
Published in Journal of pharmacological and toxicological methods (01.11.2015)
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Journal Article