Efficacy and safety of intravenous imatinib in COVID-19 ARDS: a randomized, double-blind, placebo-controlled clinical trial
Atmowihardjo, Leila N, Schippers, Job R, Duijvelaar, Erik, Bartelink, Imke H, Bet, Pierre M, Swart, Noortje E L, van Rein, Nienke, Purdy, Keith, Cavalla, David, McElroy, Andrew, Fritchley, Sarah, Vonk Noordegraaf, Anton, Endeman, Henrik, van Velzen, Patricia, Koopmans, Matty, Bogaard, Harm Jan, Heunks, Leo, Juffermans, Nicole, Schultz, Marcus J, Tuinman, Pieter R, Bos, Lieuwe D J, Aman, Jurjan
Published in Critical care (London, England) (08.06.2023)
Published in Critical care (London, England) (08.06.2023)
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The INVENT COVID trial: a structured protocol for a randomized controlled trial investigating the efficacy and safety of intravenous imatinib mesylate (Impentri®) in subjects with acute respiratory distress syndrome induced by COVID-19
Atmowihardjo, Leila, Schippers, Job R, Bartelink, Imke H, Bet, Pierre M, van Rein, Nienke, Purdy, Keith, Cavalla, David, Comberiati, Valérie, McElroy, Andrew, Snape, Sue D, Bogaard, Harm Jan, Heunks, Leo, Juffermans, Nicole, Schultz, Marcus, Tuinman, Pieter R, Bos, Lieuwe D J, Aman, Jurjan
Published in Current controlled trials in cardiovascular medicine (16.02.2022)
Published in Current controlled trials in cardiovascular medicine (16.02.2022)
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Drug repurposing: progress, challenges and recommendations
Pushpakom, Sudeep, Iorio, Francesco, Eyers, Patrick A., Escott, K. Jane, Hopper, Shirley, Wells, Andrew, Doig, Andrew, Guilliams, Tim, Latimer, Joanna, McNamee, Christine, Norris, Alan, Sanseau, Philippe, Cavalla, David, Pirmohamed, Munir
Published in Nature reviews. Drug discovery (01.01.2019)
Published in Nature reviews. Drug discovery (01.01.2019)
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APT drug R&D: the right active ingredient in the right presentation for the right therapeutic use
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Book Review
The antidepressant tianeptine reverts synaptic AMPA receptor defects caused by deficiency of CDKL5
Tramarin, Marco, Rusconi, Laura, Pizzamiglio, Lara, Barbiero, Isabella, Peroni, Diana, Scaramuzza, Linda, Guilliams, Tim, Cavalla, David, Antonucci, Flavia, Kilstrup-Nielsen, Charlotte
Published in Human molecular genetics (15.06.2018)
Published in Human molecular genetics (15.06.2018)
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Respiratory Effects of the Atypical Tricyclic Antidepressant Tianeptine in Human Models of Opioid-induced Respiratory Depression
Algera, Hyke, van der Schrier, Rutger, Cavalla, David, van Velzen, Monique, Roozekrans, Margot, McMorn, Alison, Snape, Michael, Horrigan, Joseph P., Evans, Stuart, Kiernan, Bernard, Sarton, Elise, Olofsen, Erik, Niesters, Marieke, Dahan, Albert
Published in Anesthesiology (Philadelphia) (01.10.2022)
Published in Anesthesiology (Philadelphia) (01.10.2022)
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Tianeptine prevents respiratory depression without affecting analgesic effect of opiates in conscious rats
Cavalla, David, Chianelli, Fabio, Korsak, Alla, Hosford, Patrick S., Gourine, Alexander V., Marina, Nephtali
Published in European journal of pharmacology (15.08.2015)
Published in European journal of pharmacology (15.08.2015)
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The use or generation of biomedical data and existing medicines to discover and establish new treatments for patients with rare diseases - recommendations of the IRDiRC Data Mining and Repurposing Task Force
Southall, Noel T, Natarajan, Madhusudan, Lau, Lilian Pek Lian, Jonker, Anneliene Hechtelt, Deprez, Benoît, Guilliams, Tim, Hunter, Lawrence, Rademaker, Carin Ma, Hivert, Virginie, Ardigò, Diego
Published in Orphanet journal of rare diseases (15.10.2019)
Published in Orphanet journal of rare diseases (15.10.2019)
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