Blood pressure and incidence of twelve cardiovascular diseases: lifetime risks, healthy life-years lost, and age-specific associations in 1·25 million people
Rapsomaniki, Eleni, Dr, Timmis, Adam, Prof, George, Julie, PhD, Pujades-Rodriguez, Mar, PhD, Shah, Anoop D, MRCP, Denaxas, Spiros, PhD, White, Ian R, PhD, Caulfield, Mark J, Prof, Deanfield, John E, Prof, Smeeth, Liam, Prof, Williams, Bryan, Prof, Hingorani, Aroon, Prof, Hemingway, Harry, Prof
Published in The Lancet (British edition) (31.05.2014)
Published in The Lancet (British edition) (31.05.2014)
Get full text
Journal Article
Nuclear-embedded mitochondrial DNA sequences in 66,083 human genomes
Wei, Wei, Schon, Katherine R., Elgar, Greg, Orioli, Andrea, Tanguy, Melanie, Giess, Adam, Tischkowitz, Marc, Caulfield, Mark J., Chinnery, Patrick F.
Published in Nature (London) (03.11.2022)
Published in Nature (London) (03.11.2022)
Get full text
Journal Article
Genetic risk, coronary heart disease events, and the clinical benefit of statin therapy: an analysis of primary and secondary prevention trials
Mega, Jessica L, Dr, Stitziel, Nathan O, Dr, Smith, J Gustav, MD, Chasman, Daniel I, PhD, Caulfield, Mark J, Prof, Devlin, James J, PhD, Nordio, Francesco, PhD, Hyde, Craig L, PhD, Cannon, Christopher P, Prof, Sacks, Frank M, Prof, Poulter, Neil R, Prof, Sever, Peter S, Prof, Ridker, Paul M, Prof, Braunwald, Eugene, Prof, Melander, Olle, Prof, Kathiresan, Sekar, MD, Sabatine, Marc S, Prof
Published in The Lancet (British edition) (06.06.2015)
Published in The Lancet (British edition) (06.06.2015)
Get full text
Journal Article
The 100 000 Genomes Project: bringing whole genome sequencing to the NHS
Turnbull, Clare, Scott, Richard H, Thomas, Ellen, Jones, Louise, Murugaesu, Nirupa, Pretty, Freya Boardman, Halai, Dina, Baple, Emma, Craig, Clare, Hamblin, Angela, Henderson, Shirley, Patch, Christine, O’Neill, Amanda, Devereaux, Andrew, Smith, Katherine, Martin, Antonio Rueda, Sosinsky, Alona, McDonagh, Ellen M, Sultana, Razvan, Mueller, Michael, Smedley, Damian, Toms, Adam, Dinh, Lisa, Fowler, Tom, Bale, Mark, Hubbard, Tim, Rendon, Augusto, Hill, Sue, Caulfield, Mark J
Published in BMJ (Online) (24.04.2018)
Published in BMJ (Online) (24.04.2018)
Get full text
Journal Article
Spironolactone versus placebo, bisoprolol, and doxazosin to determine the optimal treatment for drug-resistant hypertension (PATHWAY-2): a randomised, double-blind, crossover trial
Williams, Bryan, Prof, MacDonald, Thomas M, Prof, Morant, Steve, PhD, Webb, David J, Prof, Sever, Peter, Prof, McInnes, Gordon, Prof, Ford, Ian, Prof, Cruickshank, J Kennedy, Prof, Caulfield, Mark J, Prof, Salsbury, Jackie, Prof, Mackenzie, Isla, FRCP, Padmanabhan, Sandosh, FRCP, Brown, Morris J, Prof
Published in The Lancet (British edition) (21.11.2015)
Published in The Lancet (British edition) (21.11.2015)
Get full text
Journal Article
Advances in Blood Pressure Genomics
Munroe, Patricia B, Barnes, Michael R, Caulfield, Mark J
Published in Circulation research (10.05.2013)
Published in Circulation research (10.05.2013)
Get full text
Journal Article
Asymmetric recognition of the HIV-1 trimer by broadly neutralizing antibody PG9
Julien, Jean-Philippe, Lee, Jeong Hyun, Cupo, Albert, Murin, Charles D., Derking, Ronald, Hoffenberg, Simon, Caulfield, Michael J., King, C. Richter, Marozsan, Andre J., Klasse, Per Johan, Sanders, Rogier W., Moore, John P., Wilson, Ian A., Ward, Andrew B.
Published in Proceedings of the National Academy of Sciences - PNAS (12.03.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (12.03.2013)
Get full text
Journal Article
ADRA2A and IRX1 are putative risk genes for Raynaud’s phenomenon
Hartmann, Sylvia, Yasmeen, Summaira, Jacobs, Benjamin M., Denaxas, Spiros, Pirmohamed, Munir, Gamazon, Eric R., Caulfield, Mark J., Hemingway, Harry, Pietzner, Maik, Langenberg, Claudia
Published in Nature communications (12.10.2023)
Published in Nature communications (12.10.2023)
Get full text
Journal Article
Endothelial C-type natriuretic peptide maintains vascular homeostasis
Moyes, Amie J, Khambata, Rayomand S, Villar, Inmaculada, Bubb, Kristen J, Baliga, Reshma S, Lumsden, Natalie G, Xiao, Fang, Gane, Paul J, Rebstock, Anne-Sophie, Worthington, Roberta J, Simone, Michela I, Mota, Filipa, Rivilla, Fernando, Vallejo, Susana, Peiró, Concepción, Sánchez Ferrer, Carlos F, Djordjevic, Snezana, Caulfield, Mark J, MacAllister, Raymond J, Selwood, David L, Ahluwalia, Amrita, Hobbs, Adrian J
Published in The Journal of clinical investigation (01.09.2014)
Published in The Journal of clinical investigation (01.09.2014)
Get full text
Journal Article
Intraplate Basalt Alkalinity Modulated by a Lithospheric Mantle Filter at the Dunedin Volcano (New Zealand)
Pontesilli, A, Brenna, M, Ubide, T, Mollo, S, Masotta, M, Caulfield, J, Le Roux, P, Nazzari, M, Scott, J M, Scarlato, P
Published in Journal of petrology (01.10.2021)
Published in Journal of petrology (01.10.2021)
Get full text
Journal Article
Identification and validation of a novel pathogenic variant in GDF2 (BMP9) responsible for hereditary hemorrhagic telangiectasia and pulmonary arteriovenous malformations
Balachandar, Srimmitha, Graves, Tamara J., Shimonty, Anika, Kerr, Katie, Kilner, Jill, Xiao, Sihao, Slade, Richard, Sroya, Manveer, Alikian, Mary, Curetean, Emanuel, Thomas, Ellen, McConnell, Vivienne P. M., McKee, Shane, Boardman‐Pretty, Freya, Devereau, Andrew, Fowler, Tom A., Caulfield, Mark J., Alton, Eric W., Ferguson, Teena, Redhead, Julian, McKnight, Amy J., Thomas, Geraldine A., Aldred, Micheala A., Shovlin, Claire L.
Published in American journal of medical genetics. Part A (01.03.2022)
Published in American journal of medical genetics. Part A (01.03.2022)
Get full text
Journal Article
Coronary-Heart-Disease-Associated Genetic Variant at the COL4A1/COL4A2 Locus Affects COL4A1/COL4A2 Expression, Vascular Cell Survival, Atherosclerotic Plaque Stability and Risk of Myocardial Infarction
Yang, Wei, Ng, Fu Liang, Chan, Kenneth, Pu, Xiangyuan, Poston, Robin N, Ren, Meixia, An, Weiwei, Zhang, Ruoxin, Wu, Jingchun, Yan, Shunying, Situ, Haiteng, He, Xinjie, Chen, Yequn, Tan, Xuerui, Xiao, Qingzhong, Tucker, Arthur T, Caulfield, Mark J, Ye, Shu
Published in PLoS genetics (01.07.2016)
Published in PLoS genetics (01.07.2016)
Get full text
Journal Article
Genome-wide Association Study Identifies Genes for Biomarkers of Cardiovascular Disease: Serum Urate and Dyslipidemia
Wallace, Chris, Newhouse, Stephen J., Braund, Peter, Zhang, Feng, Tobin, Martin, Falchi, Mario, Ahmadi, Kourosh, Dobson, Richard J., Marçano, Ana Carolina B., Hajat, Cother, Burton, Paul, Deloukas, Panagiotis, Brown, Morris, Connell, John M., Dominiczak, Anna, Lathrop, G. Mark, Webster, John, Farrall, Martin, Spector, Tim, Samani, Nilesh J., Caulfield, Mark J., Munroe, Patricia B.
Published in American journal of human genetics (01.01.2008)
Published in American journal of human genetics (01.01.2008)
Get full text
Journal Article
Production of outer membrane vesicles by the plague pathogen Yersinia pestis
Eddy, Justin L, Gielda, Lindsay M, Caulfield, Adam J, Rangel, Stephanie M, Lathem, Wyndham W
Published in PloS one (08.09.2014)
Published in PloS one (08.09.2014)
Get full text
Journal Article
Functional analyses of coronary artery disease associated variation on chromosome 9p21 in vascular smooth muscle cells
MOTTERLE, Anna, XIANGYUAN PU, TUCKER, Arthur T, CAULFIELD, Mark J, SHU YE, WOOD, Harriet, QINGZHONG XIAO, GOR, Shivani, FU LIANG NG, CHAN, Kenneth, CROSS, Frank, SHOHREH, Beski, POSTON, Robin N
Published in Human molecular genetics (15.09.2012)
Published in Human molecular genetics (15.09.2012)
Get full text
Journal Article
Varicella-Zoster Virus–Specific Immune Responses in Elderly Recipients of a Herpes Zoster Vaccine
Levin, M. J., Oxman, M. N., J. H. Zhang, Johnson, G. R., Stanley, H., Hayward, A. R., Caulfield, M. J., Irwin, M. R., Smith, J. G., Clair, J., Chan, I. S. F., Williams, H., Harbecke, R., Marchese, R., Straus, S. E., Gershon, A., Weinberg, A.
Published in The Journal of infectious diseases (15.03.2008)
Published in The Journal of infectious diseases (15.03.2008)
Get full text
Journal Article
ADAMTS7 Cleavage and Vascular Smooth Muscle Cell Migration Is Affected by a Coronary-Artery-Disease-Associated Variant
Pu, Xiangyuan, Xiao, Qingzhong, Kiechl, Stefan, Chan, Kenneth, Ng, Fu Liang, Gor, Shivani, Poston, Robin N., Fang, Changcun, Patel, Ashish, Senver, Ece C., Shaw-Hawkins, Sue, Willeit, Johann, Liu, Chuanju, Zhu, Jianhua, Tucker, Arthur T., Xu, Qingbo, Caulfield, Mark J., Ye, Shu
Published in American journal of human genetics (07.03.2013)
Published in American journal of human genetics (07.03.2013)
Get full text
Journal Article
Extracellular volume quantification in isolated hypertension - changes at the detectable limits?
Treibel, Thomas A, Zemrak, Filip, Sado, Daniel M, Banypersad, Sanjay M, White, Steven K, Maestrini, Viviana, Barison, Andrea, Patel, Vimal, Herrey, Anna S, Davies, Ceri, Caulfield, Mark J, Petersen, Steffen E, Moon, James C
Published in Journal of cardiovascular magnetic resonance (12.08.2015)
Published in Journal of cardiovascular magnetic resonance (12.08.2015)
Get full text
Journal Article