Treatment with the HIV protease inhibitor nelfinavir triggers the unfolded protein response and may overcome proteasome inhibitor resistance of multiple myeloma in combination with bortezomib: a phase I trial (SAKK 65/08)
Driessen, Christoph, Kraus, Marianne, Joerger, Markus, Rosing, Hilde, Bader, Jürgen, Hitz, Felicitas, Berset, Catherine, Xyrafas, Alexandros, Hawle, Hanne, Berthod, Gregoire, Overkleeft, Hermann S, Sessa, Christiana, Huitema, Alwin, Pabst, Thomas, von Moos, Roger, Hess, Dagmar, Mey, Ulrich J M
Published in Haematologica (Roma) (01.03.2016)
Published in Haematologica (Roma) (01.03.2016)
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The TOR (target of rapamycin) signal transduction pathway regulates the stability of translation initiation factor eIF4G in the yeast Saccharomyces cerevisiae
Berset, C. (University of Bern, Bern, Switzerland.), Trachsel, H, Altmann, M
Published in Proceedings of the National Academy of Sciences - PNAS (14.04.1998)
Published in Proceedings of the National Academy of Sciences - PNAS (14.04.1998)
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The ISG15 Isopeptidase UBP43 Is Regulated by Proteolysis via the SCFSkp2 Ubiquitin Ligase
Tokarz, Sara, Berset, Catherine, La Rue, Janna, Friedman, Kevin, Nakayama, Kei-Ichi, Nakayama, Keiko, Zhang, Dong-Er, Lanker, Stefan
Published in The Journal of biological chemistry (05.11.2004)
Published in The Journal of biological chemistry (05.11.2004)
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A randomised phase II study of osimertinib and bevacizumab versus osimertinib alone as second-line targeted treatment in advanced NSCLC with confirmed EGFR and acquired T790M mutations: the European Thoracic Oncology Platform (ETOP 10-16) BOOSTER trial
Soo, R.A., Han, J.-Y., Dafni, U., Cho, B.C., Yeo, C.M., Nadal, E., Carcereny, E., de Castro, J., Sala, M.A., Bernabé, R., Coate, L., Provencio Pulla, M., Garcia Campelo, R., Cuffe, S., Hashemi, S.M.S., Früh, M., Massuti, B., Garcia-Sanchez, J., Dómine, M., Majem, M., Sanchez-Torres, J.-M., Britschgi, C., Pless, M., Dimopoulou, G., Roschitzki-Voser, H., Ruepp, B., Rosell, R., Stahel, R.A., Peters, S., Stahel, Rolf, Peters, Solange, Soo, Ross, Han, Ji-Youn, Früh, Martin, Provencio, Mariano, Coate, Linda, Dafni, Urania, Hiltbrunner, Anita, Ruepp, Barbara, Roschitzki-Voser, Heidi, Gasca-Ruchti, Adriana, Giacomelli, Nino, Kammler, Rosita, Marti, Nesa, Nobs, Lionel, Pardo-Contreras, Mariana, Pfister, Rita, Piguet, Anne-Christine, Ribeli-Hofmann, Sabrina, Martinez, Virginia Rodriguez, Roux, Susanne, Sanchez-Hohl, Magdalena, Schneider, Mirjam, Schweri, Robin, Troesch, Sandra, Zigomo, Isabel, Tsourti, Zoi, Zygoura, Panagiota, Kassapian, Marie, Vervita, Katerina, Dimopoulou, Georgia, Andriakopoulou, Charitini, Fernandez, Maria, Pereira, Eva, Simona, Carolina, Tucker, Lisa, Burnes, Jillian, Barrett, Aisling, McGrillen, Meghan, Berset, Catherine, Biaggi, Christine, Reist, Martin, Rentsch, Priska, Cuffe, Sinead, Hashemi, Sayed, Nadal, Ernest, Carcereny, Enric, de Castro, Javier, Sala, Maria Angeles, Reyes, Bernabé, Pulla, Mariano Provencio, Campelo, Rosario Garcia, Massutí, Bartomeu, Garcia, Jose, Dómine, Manuel, Majem, Margarita, Sanchez, Jose Miguel, Britschgi, Christian, Pless, Miklos, Yeo, Chong Ming, Cho, Byoung Chul
Published in Annals of oncology (01.02.2022)
Published in Annals of oncology (01.02.2022)
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Transferable Domain in the G1 Cyclin Cln2 Sufficient To Switch Degradation of Sic1 from the E3 Ubiquitin Ligase SCFCdc4 to SCFGrr1
Berset, Catherine, Griac, Peter, Tempel, Rebecca, La Rue, Janna, Wittenberg, Curt, Lanker, Stefan
Published in Molecular and Cellular Biology (01.07.2002)
Published in Molecular and Cellular Biology (01.07.2002)
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Fulvestrant with or without selumetinib, a MEK 1/2 inhibitor, in breast cancer progressing after aromatase inhibitor therapy: A multicentre randomised placebo-controlled double-blind phase II trial, SAKK 21/08
Zaman, Khalil, Winterhalder, Ralph, Mamot, Christoph, Hasler-Strub, Ursula, Rochlitz, Christoph, Mueller, Andreas, Berset, Catherine, Wiliders, Hans, Perey, Lucien, Rudolf, Christine Biaggi, Hawle, Hanne, Rondeau, Stephanie, Neven, Patrick
Published in European journal of cancer (1990) (01.07.2015)
Published in European journal of cancer (1990) (01.07.2015)
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Structure-based tailoring of compound libraries for high-throughput screening: Discovery of novel EphB4 kinase inhibitors
Kolb, Peter, Kipouros, Catherine Berset, Huang, Danzhi, Caflisch, Amedeo
Published in Proteins, structure, function, and bioinformatics (01.10.2008)
Published in Proteins, structure, function, and bioinformatics (01.10.2008)
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Promising activity of nelfinavir-bortezomib-dexamethasone in proteasome inhibitor–refractory multiple myeloma
Driessen, Christoph, Müller, Rouven, Novak, Urban, Cantoni, Nathan, Betticher, Daniel, Mach, Nicolas, Rüfer, Axel, Mey, Ulrich, Samaras, Panagiotis, Ribi, Karin, Besse, Lenka, Besse, Andrej, Berset, Catherine, Rondeau, Stephanie, Hawle, Hanne, Hitz, Felicitas, Pabst, Thomas, Zander, Thilo
Published in Blood (08.11.2018)
Published in Blood (08.11.2018)
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Physical activity program in patients with metastatic colorectal cancer who receive palliative first-line chemotherapy: A randomized controlled phase III trial—(ACTIVE-2 SAKK 41/14)
Hess, Viviane, Winterhalder, Ralph C., Ribi, Karin, Handschin, Barbara, Pederiva, Stefanie, Luthi, Jean-Marc, Kueng, Marc, Helbling, Daniel, Moosmann, Peter, Bohanes, Pierre Oliver, Pestalozzi, Bernhard C., Rickenbacher, Evelyn, Biaggi Rudolf, Christine, Berset, Catherine, Rondeau, Stephanie, Horber, Daniel, Thaler, Josef
Published in Journal of clinical oncology (20.05.2018)
Published in Journal of clinical oncology (20.05.2018)
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The HIV Protease Inhibitor Nelfinavir in Combination with Bortezomib and Dexamethasone (NVd) Has Excellent Activity in Patients with Advanced, Proteasome Inhibitor-Refractory Multiple Myeloma: A Multicenter Phase II Trial (SAKK 39/13)
Driessen, Christoph, Müller, Rouven, Novak, Urban, Cantoni, Nathan, Betticher, Daniel, Mach, Nicolas, Gregor, Michael, Samaras, Panagiotis, Berset, Catherine, Rondeau, Stephanie, Hawle, Hanne, Hitz, Felicitas, Pabst, Thomas, Zander, Thilo
Published in Blood (02.12.2016)
Published in Blood (02.12.2016)
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SAKK 65/08: A Phase I Dose Escalation Study of Bortezomib in Combination with Nelfinavir in Patients with Advanced Hematologic Malignancies
Driessen, Christoph, Bader, Jürgen, Kraus, Marianne, Jörger, Markus, Rosing, Hilde, Berthod, Gregoire, Hitz, Felicitas, Berset, Catherine, Xyrafas, Alexandros, Hawle, Hanne, Overkleeft, Hermann S, Sessa, Christiana, Huitema, Alwin, Mey, Ulrich JM, Pabst, Thomas, von Moos, Roger, Hess, Dagmar
Published in Blood (06.12.2014)
Published in Blood (06.12.2014)
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SAKK 65/08: A Phase I Trial of the HIV Protease Inhibitor Nelfinavir in Combination with Bortezomib Identifies Nelfinavir As FDA Approved, Oral Drug that Inhibits the Proteasome and Induces Proteotoxic Stress in Vivo and has Potential Antimyeloma Activity
Driessen, Christoph, Hess, Dagmar, Pabst, Thomas, Haile, Sarah R, Joerger, Markus, von Moos, Roger, Berset, Catherine, Crowe, Susanne, Rosing, Hilde, Overkleeft, Hermen S, Sessa, Christiana, Kraus, Marianne
Published in Blood (16.11.2012)
Published in Blood (16.11.2012)
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RNA-binding activity of translation initiation factor eIF4G1 from Saccharomyces cerevisiae
Berset, Catherine, Zurbriggen, Andreas, Djafarzadeh, Siamak, Altmann, Michael, Trachsel, Hans
Published in RNA (Cambridge) (01.07.2003)
Published in RNA (Cambridge) (01.07.2003)
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Yeast as a screening tool
Barberis, Alcide, Gunde, Tea, Berset, Catherine, Audetat, Stephan, Lüthi, Urs
Published in Drug discovery today. Technologies (2005)
Published in Drug discovery today. Technologies (2005)
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Journal Article
The ISG15 Isopeptidase UBP43 Is Regulated by Proteolysis via the SCF super(Skp2) Ubiquitin Ligase
Tokarz, Sara, Berset, Catherine, La Rue, Janna, Friedman, Kevin, Nakayama, Kei-Ichi, Nakayama, Keiko, Zhang, Dong-Er, Lanker, Stefan
Published in The Journal of biological chemistry (05.11.2004)
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Published in The Journal of biological chemistry (05.11.2004)
Journal Article
Transferable domain in the G(1) cyclin Cln2 sufficient to switch degradation of Sic1 from the E3 ubiquitin ligase SCF(Cdc4) to SCF(Grr1)
Berset, Catherine, Griac, Peter, Tempel, Rebecca, La Rue, Janna, Wittenberg, Curt, Lanker, Stefan
Published in Molecular and cellular biology (01.07.2002)
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Published in Molecular and cellular biology (01.07.2002)
Journal Article
Transferable Domain in the G 1 Cyclin Cln2 Sufficient To Switch Degradation of Sic1 from the E3 Ubiquitin Ligase SCF Cdc4 to SCF Grr1
Berset, Catherine, Griac, Peter, Tempel, Rebecca, La Rue, Janna, Wittenberg, Curt, Lanker, Stefan
Published in Molecular and cellular biology (01.07.2002)
Published in Molecular and cellular biology (01.07.2002)
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