Fibrin is a critical regulator of neutrophil effector function at the oral mucosal barrier
Silva, Lakmali M, Doyle, Andrew D, Greenwell-Wild, Teresa, Dutzan, Nicolas, Tran, Collin L, Abusleme, Loreto, Juang, Lih Jiin, Leung, Jerry, Chun, Elizabeth M, Lum, Andrew G, Agler, Cary S, Zuazo, Carlos E, Sibree, Megan, Jani, Priyam, Kram, Vardit, Martin, Daniel, Moss, Kevin, Lionakis, Michail S, Castellino, Francis J, Kastrup, Christian J, Flick, Matthew J, Divaris, Kimon, Bugge, Thomas H, Moutsopoulos, Niki M
Published in Science (American Association for the Advancement of Science) (24.12.2021)
Published in Science (American Association for the Advancement of Science) (24.12.2021)
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Early Platelet Dysfunction: An Unrecognized Role in the Acute Coagulopathy of Trauma
Wohlauer, Max V., MD, Moore, Ernest E., MD, FACS, Thomas, Scott, MD, FACS, Sauaia, Angela, MD, PhD, Evans, Ed, BA, CCP, Harr, Jeffrey, MD, MPH, Silliman, Christopher C., MD, PhD, Ploplis, Victoria, PhD, Castellino, Francis J., PhD, Walsh, Mark, MD
Published in Journal of the American College of Surgeons (01.05.2012)
Published in Journal of the American College of Surgeons (01.05.2012)
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Demonstration of Three Distinct High-Molecular-Weight Complexes between Plasminogen Activator Inhibitor Type 1 and Tissue-Type Plasminogen Activator
Ito, Tae, Suzuki, Yuko, Sano, Hideto, Honkura, Naoki, Castellino, Francis J, Urano, Tetsumei
Published in Thrombosis and haemostasis (01.03.2022)
Published in Thrombosis and haemostasis (01.03.2022)
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Traumatic brain injury causes platelet adenosine diphosphate and arachidonic acid receptor inhibition independent of hemorrhagic shock in humans and rats
Castellino, Francis J, Chapman, Michael P, Donahue, Deborah L, Thomas, Scott, Moore, Ernest E, Wohlauer, Max V, Fritz, Braxton, Yount, Robert, Ploplis, Victoria, Davis, Patrick, Evans, Edward, Walsh, Mark
Published in The journal of trauma and acute care surgery (01.05.2014)
Published in The journal of trauma and acute care surgery (01.05.2014)
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Early coagulation events induce acute lung injury in a rat model of blunt traumatic brain injury
Yasui, Hideki, Donahue, Deborah L, Walsh, Mark, Castellino, Francis J, Ploplis, Victoria A
Published in American journal of physiology. Lung cellular and molecular physiology (01.07.2016)
Published in American journal of physiology. Lung cellular and molecular physiology (01.07.2016)
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The efficacy of activated protein C in murine endotoxemia is dependent on integrin CD11b
Cao, Chunzhang, Gao, Yamei, Li, Yang, Antalis, Toni M, Castellino, Francis J, Zhang, Li
Published in The Journal of clinical investigation (01.06.2010)
Published in The Journal of clinical investigation (01.06.2010)
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Inactivation of the lysine binding sites of human plasminogen (hPg) reveals novel structural requirements for the tight hPg conformation, M-protein binding, and rapid activation
Ayinuola, Yetunde A, Castellino, Francis J
Published in Frontiers in molecular biosciences (04.04.2023)
Published in Frontiers in molecular biosciences (04.04.2023)
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The protein C pathway in tissue inflammation and injury: pathogenic role and therapeutic implications
Danese, Silvio, Vetrano, Stefania, Zhang, Li, Poplis, Victoria A., Castellino, Francis J.
Published in Blood (11.02.2010)
Published in Blood (11.02.2010)
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Targeted Thromboelastographic (TEG) Blood Component and Pharmacologic Hemostatic Therapy in Traumatic and Acquired Coagulopathy
Walsh, Mark, Fritz, Stephanie, Hake, Daniel, Son, Michael, Greve, Sarah, Jbara, Manar, Chitta, Swetha, Fritz, Braxton, Miller, Adam, Bader, Mary K, McCollester, Jonathon, Binz, Sophia, Liew-Spilger, Alyson, Thomas, Scott, Crepinsek, Anton, Shariff, Faisal, Ploplis, Victoria, Castellino, Francis J
Published in Current drug targets (01.06.2016)
Published in Current drug targets (01.06.2016)
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Fibrinolytic-deficiencies predispose hosts to septicemia from a catheter-associated UTI
Molina, Jonathan J., Kohler, Kurt N., Gager, Christopher, Andersen, Marissa J., Wongso, Ellsa, Lucas, Elizabeth R., Paik, Andrew, Xu, Wei, Donahue, Deborah L., Bergeron, Karla, Klim, Aleksandra, Caparon, Michael G., Hultgren, Scott J., Desai, Alana, Ploplis, Victoria A., Flick, Matthew J., Castellino, Francis J., Flores-Mireles, Ana L.
Published in Nature communications (27.03.2024)
Published in Nature communications (27.03.2024)
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Platelet Dysfunction is an Early Marker for Traumatic Brain Injury-Induced Coagulopathy
Davis, Patrick K., Musunuru, Harsha, Walsh, Mark, Cassady, Robert, Yount, Robert, Losiniecki, Andrew, Moore, Ernest E., Wohlauer, Max V., Howard, Janet, Ploplis, Victoria A., Castellino, Francis J., Thomas, Scott G.
Published in Neurocritical care (01.04.2013)
Published in Neurocritical care (01.04.2013)
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Endotoxemia and sepsis mortality reduction by non-anticoagulant activated protein C
Kerschen, Edward J, Fernandez, José A, Cooley, Brian C, Yang, Xia V, Sood, Rashmi, Mosnier, Laurent O, Castellino, Francis J, Mackman, Nigel, Griffin, John H, Weiler, Hartmut
Published in The Journal of experimental medicine (01.10.2007)
Published in The Journal of experimental medicine (01.10.2007)
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Activated protein C therapy slows ALS-like disease in mice by transcriptionally inhibiting SOD1 in motor neurons and microglia cells
Zhong, Zhihui, Ilieva, Hristelina, Hallagan, Lee, Bell, Robert, Singh, Itender, Paquette, Nicole, Thiyagarajan, Meenakshisundaram, Deane, Rashid, Fernandez, Jose A, Lane, Steven, Zlokovic, Anna B, Liu, Todd, Griffin, John H, Chow, Nienwen, Castellino, Francis J, Stojanovic, Konstantin, Cleveland, Don W, Zlokovic, Berislav V
Published in The Journal of clinical investigation (01.11.2009)
Published in The Journal of clinical investigation (01.11.2009)
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The M Protein of Streptococcus pyogenes Strain AP53 Retains Cell Surface Functional Plasminogen Binding after Inactivation of the Sortase A Gene
Russo, Brady T, Ayinuola, Yetunde A, Singh, Damini, Carothers, Katelyn, Fischetti, Vincent A, Flores-Mireles, Ana L, Lee, Shaun W, Ploplis, Victoria A, Liang, Zhong, Castellino, Francis J
Published in Journal of bacteriology (27.04.2020)
Published in Journal of bacteriology (27.04.2020)
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