An inter-laboratory validation of a real time PCR assay to measure host excretion of bacterial pathogens, particularly of Mycobacterium bovis
Travis, Emma R, Gaze, William H, Pontiroli, Alessandra, Sweeney, Francis P, Porter, David, Mason, Sam, Keeling, Matthew J C, Jones, Rebecca M, Sawyer, Jason, Aranaz, Alicia, Rizaldos, Elena Castellanos, Cork, Jennifer, Delahay, Richard J, Wilson, Gavin J, Hewinson, R Glyn, Courtenay, Orin, Wellington, Elizabeth M H
Published in PloS one (14.11.2011)
Published in PloS one (14.11.2011)
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DISSECT Method Using PNA-LNA Clamp Improves Detection of EGFR T790m Mutation
Guha, Minakshi, Castellanos-Rizaldos, Elena, Makrigiorgos, G Mike
Published in PloS one (21.06.2013)
Published in PloS one (21.06.2013)
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COLD-PCR amplification of bisulfite-converted DNA allows the enrichment and sequencing of rare un-methylated genomic regions
Castellanos-Rizaldos, Elena, Milbury, Coren A, Karatza, Elli, Chen, Clark C, Makrigiorgos, G Mike, Merewood, Anne
Published in PloS one (01.04.2014)
Published in PloS one (01.04.2014)
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Journal Article
Enrichment of mutations in multiple DNA sequences using COLD-PCR in emulsion
Castellanos-Rizaldos, Elena, Milbury, Coren Audrey, Makrigiorgos, G Mike
Published in PloS one (06.12.2012)
Published in PloS one (06.12.2012)
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MYOC 발현을 침묵시키기 위한 조성물 및 방법
SCHLEGEL MARK K, PANDYA BHAUMIK A, CASTORENO ADAM, JADHAV VASANT R, CASTELLANOS RIZALDOS ELENA
Year of Publication 27.02.2024
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Year of Publication 27.02.2024
Patent
Metastasis-associated MCL1 and P16 copy number alterations dictate resistance to vemurafenib in a BRAFV600E patient-derived papillary thyroid carcinoma preclinical model
Duquette, Mark, Sadow, Peter M, Husain, Amjad, Sims, Jennifer N, Antonello, Zeus A, Fischer, Andrew H, Song, Chen, Castellanos-Rizaldos, Elena, Makrigiorgos, G Mike, Kurebayashi, Junichi, Nose, Vania, Van Hummelen, Paul, Bronson, Roderick T, Vinco, Michelle, Giordano, Thomas J, Dias-Santagata, Dora, Pandolfi, Pier Paolo, Nucera, Carmelo
Published in Oncotarget (15.12.2015)
Published in Oncotarget (15.12.2015)
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간외 전달 IRNA 조성물 및 이를 이용하는 방법
NAIR JAYAPRAKASH K, ZLATEV IVAN, ANGLERO RODRIGUEZ YESSEINIA, MAIER MARTIN A, NAKATA MASAAKI, SCHMIDT KARYN, BONDURANT LUCAS D, PIERSON JUSTIN, KEL'IN ALEXANDER, JADHAV VASANT R, CASTELLANOS RIZALDOS ELENA, DOOLEY KEVIN
Year of Publication 02.07.2024
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Year of Publication 02.07.2024
Patent
VEGF-A 발현을 사일런싱하기 위한 조성물 및 방법
SCHLEGEL MARK K, KAITTANIS CHARALAMBOS, PANDYA BHAUMIK A, KEATING MARK, MCININCH JAMES D, CASTORENO ADAM, JADHAV VASANT R, CASTELLANOS RIZALDOS ELENA
Year of Publication 18.10.2022
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Year of Publication 18.10.2022
Patent
변형 이중 가닥 올리고뉴클레오타이드
MILSTEIN STUART, GILBERT JASON, SOUNDARAPANDIAN MANGALA MEENAKSHI, BORODOVSKY ANNA, ZUBER JEFFREY, MCININCH JAMES D, FISHILEVICH ELANE, CASTORENO ADAM, FARLEY JONATHAN EDWARD, CASTELLANOS RIZALDOS ELENA, CANTLEY WILLIAM, SCHLEGEL MARK K, LIU JINGXUAN, KAITTANIS CHARALAMBOS, PANDYA BHAUMIK A, BONDURANT LUCAS D, BROWN CHRISTOPHER, DEATON AIMEE M, KEATING MARK, GANSNER JOHN MICHAEL, JADHAV VASANT R
Year of Publication 21.09.2023
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Year of Publication 21.09.2023
Patent
역형성 림프종 키나아제(ALK) 핵산 및 ALK 융합 전사물의 혈장 기반 검출 및 암의 진단 및 치료에 있어 이의 용도
SKOG JOHAN KARL OLOV, BRINKMAN KAY, NOERHOLM MIKKEL, HURLEY JAMES, CASTELLANOS RIZALDOS ELENA
Year of Publication 04.03.2019
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Year of Publication 04.03.2019
Patent
Exosome-Based Detection of EGFR T790M in Plasma from Non-Small Cell Lung Cancer Patients
Castellanos-Rizaldos, Elena, Grimm, Dominik G, Tadigotla, Vasisht, Hurley, James, Healy, John, Neal, Patricia L, Sher, Mia, Venkatesan, Raajdeep, Karlovich, Chris, Raponi, Mitch, Krug, Anne, Noerholm, Mikkel, Tannous, Jihane, Tannous, Bakhos A, Raez, Luis E, Skog, Johan K
Published in Clinical cancer research (15.06.2018)
Published in Clinical cancer research (15.06.2018)
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Expanding RNAi therapeutics to extrahepatic tissues with lipophilic conjugates
Brown, Kirk M., Nair, Jayaprakash K., Janas, Maja M., Anglero-Rodriguez, Yesseinia I., Dang, Lan T. H., Peng, Haiyan, Theile, Christopher S., Castellanos-Rizaldos, Elena, Brown, Christopher, Foster, Donald, Kurz, Jeffrey, Allen, Jeffrey, Maganti, Rajanikanth, Li, Jing, Matsuda, Shigeo, Stricos, Matthew, Chickering, Tyler, Jung, Michelle, Wassarman, Kelly, Rollins, Jeff, Woods, Lauren, Kelin, Alex, Guenther, Dale C., Mobley, Melissa W., Petrulis, John, McDougall, Robin, Racie, Timothy, Bombardier, Jessica, Cha, Diana, Agarwal, Saket, Johnson, Lei, Jiang, Yongfeng, Lentini, Scott, Gilbert, Jason, Nguyen, Tuyen, Chigas, Samantha, LeBlanc, Sarah, Poreci, Urjana, Kasper, Anne, Rogers, Arlin B., Chong, Saeho, Davis, Wendell, Sutherland, Jessica E., Castoreno, Adam, Milstein, Stuart, Schlegel, Mark K., Zlatev, Ivan, Charisse, Klaus, Keating, Mark, Manoharan, Muthiah, Fitzgerald, Kevin, Wu, Jing-Tao, Maier, Martin A., Jadhav, Vasant
Published in Nature biotechnology (01.10.2022)
Published in Nature biotechnology (01.10.2022)
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The Nonclinical Disposition and Pharmacokinetic/Pharmacodynamic Properties of N -Acetylgalactosamine-Conjugated Small Interfering RNA Are Highly Predictable and Build Confidence in Translation to Human
McDougall, Robin, Ramsden, Diane, Agarwal, Sagar, Agarwal, Saket, Aluri, Krishna, Arciprete, Michael, Brown, Christopher, Castellanos-Rizaldos, Elena, Charisse, Klaus, Chong, Saeho, Cichocki, Joseph, Fitzgerald, Kevin, Goel, Varun, Gu, Yongli, Guenther, Dale, Habtemariam, Bahru, Jadhav, Vasant, Janas, Maja, Jayaraman, Muthusamy, Kurz, Jeffrey, Li, Jing, Liu, Ju, Liu, Xiumin, Liou, Steven, Maclauchlin, Chris, Maier, Martin, Manoharan, Muthiah, Nair, Jayaprakash K, Robbie, Gabriel, Schmidt, Karyn, Smith, Peter, Theile, Christopher, Vaishnaw, Akshay, Waldron, Scott, Xu, Yuanxin, Zhang, Xuemei, Zlatev, Ivan, Wu, Jing-Tao
Published in Drug metabolism and disposition (01.06.2022)
Published in Drug metabolism and disposition (01.06.2022)
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Exosome-based detection of activating and resistance EGFR mutations from plasma of non-small cell lung cancer patients
Castellanos-Rizaldos, Elena, Zhang, Xuan, Tadigotla, Vasisht R, Grimm, Dominik G, Karlovich, Chris, Raez, Luis E, Skog, Johan K
Published in Oncotarget (23.04.2019)
Published in Oncotarget (23.04.2019)
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Evaluating the oral delivery of GalNAc-conjugated siRNAs in rodents and non-human primates
Yu, Mikyung, Qin, June, Liu, Xiumin, Ramsden, Diane, Williams, Brian, Zlatev, Ivan, Guenther, Dale, Matsuda, Shigeo, Tymon, Roxanne, Darcy, Justin, Wong, Catrina, Tsung, Jamie, Zawaneh, Peter, Chong, Saeho, Theile, Christopher S, Taneja, Nathan, Rogers, Arlin, Liu, Ju, Castellanos-Rizaldos, Elena, Bond, Sarah, So, Kawai, Denoncourt, Jason, Castoreno, Adam, Manoharan, Muthiah, Wu, Jing-Tao, Fitzgerald, Kevin, Maier, Martin A, Jadhav, Vasant, Nair, Jayaprakash K
Published in Nucleic acids research (14.05.2024)
Published in Nucleic acids research (14.05.2024)
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309 Highly Sensitive Detection of the IDH1 R132H Mutation in the Plasma of Glioma Patients
Balaj, Leonora, Carter, Bob S, Castellanos-Rizaldos, Elena, Peruzzi, Pier Paolo, Chan, Dalin, Zhang, Xuan, Skog, Johan
Published in Neurosurgery (01.09.2018)
Published in Neurosurgery (01.09.2018)
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Journal Article
Differential strand separation at critical temperature: a minimally disruptive enrichment method for low-abundance unknown DNA mutations
Guha, Minakshi, Castellanos-Rizaldos, Elena, Liu, Pingfang, Mamon, Harvey, Makrigiorgos, G Mike
Published in Nucleic acids research (01.02.2013)
Published in Nucleic acids research (01.02.2013)
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Journal Article
RT-qPCR Methods to Support Pharmacokinetics and Drug Mechanism of Action to Advance Development of RNAi Therapeutics
Castellanos-Rizaldos, Elena, Brown, Christopher R, Dennin, Sean, Kim, Joohwan, Gupta, Swati, Najarian, Diana, Gu, Yongli, Aluri, Krishna, Enders, Jennifer, Brown, Kirk, Xu, Yuanxin
Published in Nucleic acid therapeutics (01.06.2020)
Published in Nucleic acid therapeutics (01.06.2020)
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