Saturated fatty acids produce an inflammatory response predominantly through the activation of TLR4 signaling in hypothalamus: implications for the pathogenesis of obesity
Milanski, Marciane, Degasperi, Giovanna, Coope, Andressa, Morari, Joseane, Denis, Raphael, Cintra, Dennys E, Tsukumo, Daniela M L, Anhe, Gabriel, Amaral, Maria E, Takahashi, Hilton K, Curi, Rui, Oliveira, Helena C, Carvalheira, José B C, Bordin, Silvana, Saad, Mário J, Velloso, Lício A
Published in The Journal of neuroscience (14.01.2009)
Published in The Journal of neuroscience (14.01.2009)
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Topical insulin accelerates wound healing in diabetes by enhancing the AKT and ERK pathways: a double-blind placebo-controlled clinical trial
Lima, Maria H M, Caricilli, Andréa M, de Abreu, Lélia L, Araújo, Eliana P, Pelegrinelli, Fabiana F, Thirone, Ana C P, Tsukumo, Daniela M, Pessoa, Ana Flávia M, dos Santos, Marinilce F, de Moraes, Maria A, Carvalheira, José B C, Velloso, Lício A, Saad, Mario J A
Published in PloS one (25.05.2012)
Published in PloS one (25.05.2012)
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Hypothalamic S1P/S1PR1 axis controls energy homeostasis
Silva, Vagner R R, Micheletti, Thayana O, Pimentel, Gustavo D, Katashima, Carlos K, Lenhare, Luciene, Morari, Joseane, Mendes, Maria Carolina S, Razolli, Daniela S, Rocha, Guilherme Z, de Souza, Claudio T, Ryu, Dongryeol, Prada, Patrícia O, Velloso, Lício A, Carvalheira, José B C, Pauli, José Rodrigo, Cintra, Dennys E, Ropelle, Eduardo R
Published in Nature communications (25.09.2014)
Published in Nature communications (25.09.2014)
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Journal Article
Acute exercise suppresses hypothalamic PTP1B protein level and improves insulin and leptin signaling in obese rats
Chiarreotto-Ropelle, Eloize C, Pauli, Luciana S S, Katashima, Carlos K, Pimentel, Gustavo D, Picardi, Paty K, Silva, Vagner R R, de Souza, Claudio T, Prada, Patrícia O, Cintra, Dennys E, Carvalheira, José B C, Ropelle, Eduardo R, Pauli, José R
Published in American journal of physiology: endocrinology and metabolism (01.09.2013)
Published in American journal of physiology: endocrinology and metabolism (01.09.2013)
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Journal Article
PSMA whole-body tumor burden in primary staging and biochemical recurrence of prostate cancer
Santos, Allan, Mattiolli, Aline, Carvalheira, José BC, Ferreira, Ubirajara, Camacho, Mariana, Silva, Cleide, Costa, Fernanda, Matheus, Wagner, Lima, Mariana, Etchebehere, Elba
Published in European journal of nuclear medicine and molecular imaging (01.02.2021)
Published in European journal of nuclear medicine and molecular imaging (01.02.2021)
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Journal Article
Diacerhein Improves Glucose Tolerance and Insulin Sensitivity in Mice on a High-Fat Diet
Tobar, Natália, Oliveira, Alexandre G, Guadagnini, Dioze, Bagarolli, Renata A, Rocha, Guilherme Z, Araújo, Tiago G, Santos-Silva, Junia C, Zollner, Ricardo L, Boechat, Luiz H. B, Carvalheira, José B. C, Prada, Patrícia O, Saad, Mario J. A
Published in Endocrinology (Philadelphia) (01.11.2011)
Published in Endocrinology (Philadelphia) (01.11.2011)
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Journal Article
Exercise intensity, inflammatory signaling, and insulin resistance in obese rats
Da Silva, Adelino S R, Pauli, José R, Ropelle, Eduardo R, Oliveira, Alexandre G, Cintra, Dennys E, De Souza, Claudio T, Velloso, Lício A, Carvalheira, José B C, Saad, Mario J A
Published in Medicine and science in sports and exercise (01.12.2010)
Published in Medicine and science in sports and exercise (01.12.2010)
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Journal Article
Reversal of diet-induced insulin resistance with a single bout of exercise in the rat: the role of PTP1B and IRS-1 serine phosphorylation
Ropelle, Eduardo R., Pauli, José R., Prada, Patrícia O., De Souza, Cláudio T., Picardi, Paty K., Faria, Marcel C., Cintra, Dennys E., Fernandes, Maria Fernanda de A., Flores, Marcelo B., Velloso, Lício A., Saad, Mario J. A., Carvalheira, José B. C.
Published in The Journal of physiology (15.12.2006)
Published in The Journal of physiology (15.12.2006)
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Journal Article
Central exercise action increases the AMPK and mTOR response to leptin
Ropelle, Eduardo R, Fernandes, Maria Fernanda A, Flores, Marcelo B S, Ueno, Mirian, Rocco, Silvana, Marin, Rodrigo, Cintra, Dennys E, Velloso, Lício A, Franchini, Kleber G, Saad, Mario J A, Carvalheira, José B C
Published in PloS one (04.12.2008)
Published in PloS one (04.12.2008)
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Journal Article
Inhibition of hypothalamic Foxo1 expression reduced food intake in diet-induced obesity rats
Ropelle, Eduardo R., Pauli, José R., Prada, Patrícia, Cintra, Dennys E., Rocha, Guilherme Z., Moraes, Juliana C., Frederico, Marisa J. S., da Luz, Gabrielle, Pinho, Ricardo A., Carvalheira, José B. C., Velloso, Licio A., Saad, Mario A., De Souza, Cláudio T.
Published in The Journal of physiology (15.05.2009)
Published in The Journal of physiology (15.05.2009)
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Journal Article
Metformin Amplifies Chemotherapy-Induced AMPK Activation and Antitumoral Growth
ROCHA, Guilherme Z, DIAS, Marília M, ROPELLE, Eduardo R, OSORIO-COSTA, Felipe, ROSSATO, Franco A, VERCESI, Anibal E, SAAD, Mario J. A, CARVALHEIRA, José B. C
Published in Clinical cancer research (15.06.2011)
Published in Clinical cancer research (15.06.2011)
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Journal Article
Acute physical exercise reverses S-nitrosation of the insulin receptor, insulin receptor substrate 1 and protein kinase B/Akt in diet-induced obese Wistar rats
Pauli, José R., Ropelle, Eduardo R., Cintra, Dennys E., Carvalho‐Filho, Marco A., Moraes, Juliana C., De Souza, Cláudio T., Velloso, Lício A., Carvalheira, José B. C., Saad, Mario J. A.
Published in The Journal of physiology (15.01.2008)
Published in The Journal of physiology (15.01.2008)
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Journal Article
Molecular and neuroendocrine mechanisms of cancer cachexia
Mendes, Maria Carolina S, Pimentel, Gustavo D, Costa, Felipe O, Carvalheira, José B C
Published in Journal of endocrinology (01.09.2015)
Published in Journal of endocrinology (01.09.2015)
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Journal Article
Novel Signal Transduction Pathway for Luteinizing Hormone and Its Interaction with Insulin: Activation of Janus Kinase/Signal Transducer and Activator of Transcription and Phosphoinositol 3-Kinase/Akt Pathways
Carvalho, Carla R. O, Carvalheira, José B. C, Lima, Maria H. M, Zimmerman, Suzana F, Caperuto, Luciana C, Amanso, Angélica, Gasparetti, Alessandra L, Meneghetti, Vainer, Zimmerman, Leonardo F, Velloso, Licio A, Saad, Mario J. A
Published in Endocrinology (Philadelphia) (01.02.2003)
Published in Endocrinology (Philadelphia) (01.02.2003)
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Journal Article
Loss-of-Function Mutation in Toll-Like Receptor 4 Prevents Diet-Induced Obesity and Insulin Resistance
TSUKUMO, Daniela M. L, CARVALHO-FILHO, Marco A, SAAD, Mario J. A, CARVALHEIRA, José B. C, PRADA, Patricia O, HIRABARA, Sandro M, SCHENKA, André A, ARAUJO, Eliana P, VASSALLO, José, CURI, Rui, VELLOSO, Licio A
Published in Diabetes (New York, N.Y.) (01.08.2007)
Published in Diabetes (New York, N.Y.) (01.08.2007)
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Journal Article
The Cross-Talk between Angiotensin and Insulin Differentially Affects Phosphatidylinositol 3-Kinase- and Mitogen-Activated Protein Kinase-Mediated Signaling in Rat Heart: Implications for Insulin Resistance
Carvalheira, José B. C, Calegari, Vivian C, Zecchin, Henrique G, Nadruz, Wilson, Guimarães, Regina B, Ribeiro, Eliane B, Franchini, Kleber G, Velloso, Lício A, Saad, Mario J. A
Published in Endocrinology (Philadelphia) (01.12.2003)
Published in Endocrinology (Philadelphia) (01.12.2003)
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Journal Article
Targeted Disruption of Inducible Nitric Oxide Synthase Protects Against Aging, S-Nitrosation, and Insulin Resistance in Muscle of Male Mice
ROPELLE, Eduardo R, PAULI, Jose R, HIRABARA, Sandro, RUI CURI, VELLOSO, Licio A, SAAD, Mario J. A, CARVALHEIRA, Jose B. C, CINTRA, Dennys E, DA SILVA, Adelino S, DE SOUZA, Claudio T, GUADAGNINI, Dioze, CARVALHO, Bruno M, CARICILLI, Andrea M, KATASHIMA, Carlos K, CARVALHO-FILHO, Marco A
Published in Diabetes (New York, N.Y.) (01.02.2013)
Published in Diabetes (New York, N.Y.) (01.02.2013)
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Journal Article
Regulation of Cbl-Associated Protein/Cbl Pathway in Muscle and Adipose Tissues of Two Animal Models of Insulin Resistance
Thirone, Ana C. P, Carvalheira, José B. C, Hirata, Aparecida E, Velloso, Lício A, Saad, Mario J. A
Published in Endocrinology (Philadelphia) (01.01.2004)
Published in Endocrinology (Philadelphia) (01.01.2004)
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Journal Article
Antineoplastic effect of rapamycin is potentiated by inhibition of IRS-1 signaling in prostate cancer cells xenografts
Oliveira, Josenilson C., Souza, Kellen K., Dias, Marília M., Faria, Marcel C., Ropelle, Eduardo R., Flores, Marcelo B. S., Ueno, Mirian, Velloso, Lício A., Saad, Sara T., Saad, Mario J. A., Carvalheira, José B. C.
Published in Journal of cancer research and clinical oncology (01.08.2008)
Published in Journal of cancer research and clinical oncology (01.08.2008)
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Journal Article
A Central Role for Neuronal AMP-Activated Protein Kinase (AMPK) and Mammalian Target of Rapamycin (mTOR) in High-Protein Diet–Induced Weight Loss
ROPELLE, Eduardo R, PAULI, José R, FRANCHINI, Kleber G, VELLOSO, Licio A, SAAD, Mario J. A, CARVALHEIRA, José B. C, FERNANDES, Maria Fernanda A, ROCCO, Silvana A, MARIN, Rodrigo M, MORARI, Joseane, SOUZA, Kellen K, DIAS, Marilia M, GOMES-MARCONDES, Maria C, GONTIJO, José A. R
Published in Diabetes (New York, N.Y.) (01.03.2008)
Published in Diabetes (New York, N.Y.) (01.03.2008)
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