Small molecules and their impact in drug discovery: A perspective on the occasion of the 125th anniversary of the Bayer Chemical Research Laboratory
Beck, Hartmut, Härter, Michael, Haß, Bastian, Schmeck, Carsten, Baerfacker, Lars
Published in Drug discovery today (01.06.2022)
Published in Drug discovery today (01.06.2022)
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Journal Article
Stereoselective Mukaiyama-Michael/Michael/Aldol Domino Cyclization as the Key Step in the Synthesis of Pentasubstituted Arenes: An Efficient Access to Highly Active Inhibitors of Cholesteryl Ester Transfer Protein (CETP)
Paulsen, Holger, Antons, Stefan, Brandes, Arndt, Lögers, Michael, Müller, Stephan Nicholas, Naab, Paul, Schmeck, Carsten, Schneider, Stephan, Stoltefuß, Jürgen
Published in Angewandte Chemie (International ed.) (15.11.1999)
Published in Angewandte Chemie (International ed.) (15.11.1999)
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Journal Article
Pharmacological inhibition of Vanin-1 is not protective in models of acute and chronic kidney disease
Unterschemmann, Kerstin, Ehrmann, Alexander, Herzig, Ina, Andreevski, Anna-Lena, Lustig, Klemens, Schmeck, Carsten, Eitner, Frank, Grundmann, Manuel
Published in American journal of physiology. Renal physiology (01.01.2021)
Published in American journal of physiology. Renal physiology (01.01.2021)
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Journal Article
Cardiac output improvement by pecavaptan: a novel dual‐acting vasopressin V1a/V2 receptor antagonist in experimental heart failure
Mondritzki, Thomas, Mai, Thuy Anh, Vogel, Julia, Pook, Elisabeth, Wasnaire, Pierre, Schmeck, Carsten, Hüser, Jörg, Dinh, Wilfried, Truebel, Hubert, Kolkhof, Peter
Published in European journal of heart failure (01.05.2021)
Published in European journal of heart failure (01.05.2021)
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Journal Article
Pharmacological Inhibition of Vanin 1 Is Not Protective in Models of Acute and Chronic Kidney Disease: PO2372
Unterschemmann, Kerstin D., Ehrmann, Alexander, Herzig, Ina D., Andreevski, Anna Lena, Schmeck, Carsten, Eitner, Frank, Grundmann, Manuel
Published in Journal of the American Society of Nephrology (01.10.2020)
Published in Journal of the American Society of Nephrology (01.10.2020)
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Journal Article
A useful application of benzyl trichloroacetimidate for the benzylation of alcohols
Eckenberg, Peter, Groth, Ulrich, Huhn, Thomas, Richter, Norbert, Schmeck, Carsten
Published in Tetrahedron (1993)
Published in Tetrahedron (1993)
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Journal Article
Fluorine-substitution in cholesteryl ester transfer protein inhibitors (CETP-inhibitors) - Biology, chemistry, SAR, and properties
Paulsen, H, Schmeck, C, Brandes, A, Schmidt, G, Stoltefuss, J, Wirtz, SN, Logers, M, Naab, P, Bremm, KD, Bischoff, H, Schmidt, D, Zaiss, S, Antons, S
Published in Chimia (01.03.2004)
Published in Chimia (01.03.2004)
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Vascular Protection and Decongestion Without Renin-Angiotensin-Aldosterone System Stimulation Mediated by a Novel Dual-Acting Vasopressin V1a/V2 Receptor Antagonist
Kolkhof, Peter, Pook, Elisabeth, Pavkovic, Mira, Kretschmer, Axel, Buchmüller, Anja, Tinel, Hanna, Delbeck, Martina, Mondritzki, Thomas, Wasnaire, Pierre, Dinh, Wilfried, Truebel, Hubert, Hüser, Jörg, Schmeck, Carsten
Published in Journal of cardiovascular pharmacology (01.07.2019)
Published in Journal of cardiovascular pharmacology (01.07.2019)
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Journal Article
Cholesteryl ester transfer protein and its inhibition
Weber, Olaf, Bischoff, Hilmar, Schmeck, Carsten, Böttcher, Michael-Friedrich
Published in Cellular and molecular life sciences : CMLS (01.09.2010)
Published in Cellular and molecular life sciences : CMLS (01.09.2010)
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Journal Article
Improving the hit-to-lead process: data-driven assessment of drug-like and lead-like screening hits
Wunberg, Tobias, Hendrix, Martin, Hillisch, Alexander, Lobell, Mario, Meier, Heinrich, Schmeck, Carsten, Wild, Hanno, Hinzen, Berthold
Published in Drug discovery today (01.02.2006)
Published in Drug discovery today (01.02.2006)
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Journal Article
Novel tetrahydrochinoline derived CETP inhibitors
Schmeck, Carsten, Gielen-Haertwig, Heike, Vakalopoulos, Alexandros, Bischoff, Hilmar, Li, Volkhart, Wirtz, Gabriele, Weber, Olaf
Published in Bioorganic & medicinal chemistry letters (01.03.2010)
Published in Bioorganic & medicinal chemistry letters (01.03.2010)
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Journal Article
In Silico ADMET Traffic Lights as a Tool for the Prioritization of HTS Hits
Lobell, Mario, Hendrix, Martin, Hinzen, Berthold, Keldenich, Jörg, Meier, Heinrich, Schmeck, Carsten, Schohe-Loop, Rudolf, Wunberg, Tobias, Hillisch, Alexander
Published in ChemMedChem (01.11.2006)
Published in ChemMedChem (01.11.2006)
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Journal Article
Chromanol derivatives—A novel class of CETP inhibitors
Vakalopoulos, Alexandros, Schmeck, Carsten, Thutewohl, Michael, Li, Volkhart, Bischoff, Hilmar, Lustig, Klemens, Weber, Olaf, Paulsen, Holger, Elias, Harry
Published in Bioorganic & medicinal chemistry letters (01.01.2011)
Published in Bioorganic & medicinal chemistry letters (01.01.2011)
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Journal Article
Prediction of a potentially effective dose in humans for BAY 60–5521, a potent inhibitor of cholesteryl ester transfer protein (CETP) by allometric species scaling and combined pharmacodynamic and physiologically‐based pharmacokinetic modelling
Weber, Olaf, Willmann, Stefan, Bischoff, Hilmar, Li, Volkhart, Vakalopoulos, Alexandros, Lustig, Klemens, Hafner, Frank‐Thorsten, Heinig, Roland, Schmeck, Carsten, Buehner, Klaus
Published in British journal of clinical pharmacology (01.02.2012)
Published in British journal of clinical pharmacology (01.02.2012)
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Journal Article
Single dose pharmacokinetics, pharmacodynamics, tolerability and safety of BAY 60–5521, a potent inhibitor of cholesteryl ester transfer protein
Boettcher, Michael‐Friedrich, Heinig, Roland, Schmeck, Carsten, Kohlsdorfer, Christian, Ludwig, Matthias, Schaefer, Anja, Gelfert‐Peukert, Sabine, Wensing, Georg, Weber, Olaf
Published in British journal of clinical pharmacology (01.02.2012)
Published in British journal of clinical pharmacology (01.02.2012)
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Journal Article
SUBSTITUTED PIPERIDINYL-TETRAHYDROQUINOLINES AND THEIR USE AS α-2C ADRENORECEPTOR ANTAGONISTS
FRANK WUNDER, CARSTEN SCHMECK, ANJA BUCHMUELLER, RAIMUND KAST, HANNA TINEL, DIETER LANG, GORDEN REDLICH, ANDREAS GOELLER, KAREN ENGEL, VOLKER GEISS, HERBERT HIMMEL, ANDREAS KNORR, PHILIPP BUCHGRABER, EVA MARIA BECKER-PELSTER
Year of Publication 28.03.2019
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Year of Publication 28.03.2019
Patent
Differentiation of arginine vasopressin antagonistic effects by selective V2 versus dual V2/V1a receptor blockade in a preclinical heart failure model
Mondritzki, Thomas, Kolkhof, Peter, Sabbah, Hani N, Gheorghiade, Mihai, Fürstner, Chantal, Schmeck, Carsten, Siedentop, Harald, Schaefer, Stefan, Truebel, Hubert
Published in American journal of therapeutics (01.01.2011)
Published in American journal of therapeutics (01.01.2011)
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Journal Article
Novel heterocyclic thyromimetics. Part 2
Haning, Helmut, Mueller, Ulrich, Schmidt, Gunter, Schmeck, Carsten, Voehringer, Verena, Kretschmer, Axel, Bischoff, Hilmar
Published in Bioorganic & medicinal chemistry letters (15.07.2007)
Published in Bioorganic & medicinal chemistry letters (15.07.2007)
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Journal Article
Stable Polymer-Bound Iodine Azide
Kirschning, Andreas, Monenschein, Holger, Schmeck, Carsten
Published in Angewandte Chemie (International ed.) (03.09.1999)
Published in Angewandte Chemie (International ed.) (03.09.1999)
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