Brain tyrosinase overexpression implicates age-dependent neuromelanin production in Parkinson’s disease pathogenesis
Carballo-Carbajal, Iria, Laguna, Ariadna, Romero-Giménez, Jordi, Cuadros, Thais, Bové, Jordi, Martinez-Vicente, Marta, Parent, Annabelle, Gonzalez-Sepulveda, Marta, Peñuelas, Núria, Torra, Albert, Rodríguez-Galván, Beatriz, Ballabio, Andrea, Hasegawa, Takafumi, Bortolozzi, Analía, Gelpi, Ellen, Vila, Miquel
Published in Nature communications (07.03.2019)
Published in Nature communications (07.03.2019)
Get full text
Journal Article
Disease‐specific phenotypes in dopamine neurons from human iPS‐based models of genetic and sporadic Parkinson's disease
Sánchez‐Danés, Adriana, Richaud‐Patin, Yvonne, Carballo‐Carbajal, Iria, Jiménez‐Delgado, Senda, Caig, Carles, Mora, Sergio, Di Guglielmo, Claudia, Ezquerra, Mario, Patel, Bindiben, Giralt, Albert, Canals, Josep M., Memo, Maurizio, Alberch, Jordi, López‐Barneo, José, Vila, Miquel, Cuervo, Ana Maria, Tolosa, Eduard, Consiglio, Antonella, Raya, Angel
Published in EMBO molecular medicine (01.05.2012)
Published in EMBO molecular medicine (01.05.2012)
Get full text
Journal Article
Aberrant epigenome in iPSC‐derived dopaminergic neurons from Parkinson's disease patients
Fernández‐Santiago, Rubén, Carballo‐Carbajal, Iria, Castellano, Giancarlo, Torrent, Roger, Richaud, Yvonne, Sánchez‐Danés, Adriana, Vilarrasa‐Blasi, Roser, Sánchez‐Pla, Alex, Mosquera, José Luis, Soriano, Jordi, López‐Barneo, José, Canals, Josep M, Alberch, Jordi, Raya, Ángel, Vila, Miquel, Consiglio, Antonella, Martín‐Subero, José I, Ezquerra, Mario, Tolosa, Eduardo
Published in EMBO molecular medicine (01.12.2015)
Published in EMBO molecular medicine (01.12.2015)
Get full text
Journal Article
Lewy body extracts from Parkinson disease brains trigger α-synuclein pathology and neurodegeneration in mice and monkeys
Recasens, Ariadna, Dehay, Benjamin, Bové, Jordi, Carballo-Carbajal, Iria, Dovero, Sandra, Pérez-Villalba, Ana, Fernagut, Pierre-Olivier, Blesa, Javier, Parent, Annabelle, Perier, Celine, Fariñas, Isabel, Obeso, José A., Bezard, Erwan, Vila, Miquel
Published in Annals of neurology (01.03.2014)
Published in Annals of neurology (01.03.2014)
Get full text
Journal Article
Chitinase 3-like 1 is neurotoxic in primary cultured neurons
Matute-Blanch, Clara, Calvo-Barreiro, Laura, Carballo-Carbajal, Iria, Gonzalo, Ricardo, Sanchez, Alex, Vila, Miquel, Montalban, Xavier, Comabella, Manuel
Published in Scientific reports (28.04.2020)
Published in Scientific reports (28.04.2020)
Get full text
Journal Article
Advances in Parkinson's Disease: 200 Years Later
Del Rey, Natalia López-González, Quiroga-Varela, Ana, Garbayo, Elisa, Carballo-Carbajal, Iria, Fernández-Santiago, Rubén, Monje, Mariana H G, Trigo-Damas, Inés, Blanco-Prieto, María J, Blesa, Javier
Published in Frontiers in neuroanatomy (14.12.2018)
Published in Frontiers in neuroanatomy (14.12.2018)
Get full text
Journal Article
Modelling human neuronal catecholaminergic pigmentation in rodents recapitulates age-related neurodegenerative deficits
Laguna, Ariadna, Peñuelas, Núria, Gonzalez-Sepulveda, Marta, Nicolau, Alba, Arthaud, Sébastien, Guillard-Sirieix, Camille, Lorente-Picón, Marina, Compte, Joan, Miquel-Rio, Lluís, Xicoy, Helena, Liu, Jiong, Parent, Annabelle, Cuadros, Thais, Romero-Giménez, Jordi, Pujol, Gemma, Giménez-Llort, Lydia, Fort, Patrice, Bortolozzi, Analia, Carballo-Carbajal, Iria, Vila, Miquel
Published in Nature communications (11.10.2024)
Published in Nature communications (11.10.2024)
Get full text
Journal Article
Lack of pathogenic potential of peripheral α-synuclein aggregates from Parkinson's disease patients
Recasens, Ariadna, Carballo-Carbajal, Iria, Parent, Annabelle, Bové, Jordi, Gelpi, Ellen, Tolosa, Eduardo, Vila, Miquel
Published in Acta neuropathologica communications (08.02.2018)
Published in Acta neuropathologica communications (08.02.2018)
Get full text
Journal Article
Selective α-Synuclein Knockdown in Monoamine Neurons by Intranasal Oligonucleotide Delivery: Potential Therapy for Parkinson’s Disease
Alarcón-Arís, Diana, Recasens, Ariadna, Galofré, Mireia, Carballo-Carbajal, Iria, Zacchi, Nicolás, Ruiz-Bronchal, Esther, Pavia-Collado, Rubén, Chica, Rosario, Ferrés-Coy, Albert, Santos, Marina, Revilla, Raquel, Montefeltro, Andrés, Fariñas, Isabel, Artigas, Francesc, Vila, Miquel, Bortolozzi, Analia
Published in Molecular therapy (07.02.2018)
Published in Molecular therapy (07.02.2018)
Get full text
Journal Article
Loss-of-Function of Human PINK1 Results in Mitochondrial Pathology and Can Be Rescued by Parkin
Exner, Nicole, Treske, Bettina, Paquet, Dominik, Holmstrom, Kira, Schiesling, Carola, Gispert, Suzana, Carballo-Carbajal, Iria, Berg, Daniela, Hoepken, Hans-Hermann, Gasser, Thomas, Kruger, Rejko, Winklhofer, Konstanze F, Vogel, Frank, Reichert, Andreas S, Auburger, Georg, Kahle, Philipp J, Schmid, Bettina, Haass, Christian
Published in The Journal of neuroscience (07.11.2007)
Published in The Journal of neuroscience (07.11.2007)
Get full text
Journal Article
Mutations in LRRK2 Cause Autosomal-Dominant Parkinsonism with Pleomorphic Pathology
Zimprich, Alexander, Biskup, Saskia, Leitner, Petra, Lichtner, Peter, Farrer, Matthew, Lincoln, Sarah, Kachergus, Jennifer, Hulihan, Mary, Uitti, Ryan J., Calne, Donald B., Stoessl, A.Jon, Pfeiffer, Ronald F., Patenge, Nadja, Carbajal, Iria Carballo, Vieregge, Peter, Asmus, Friedrich, Müller-Myhsok, Bertram, Dickson, Dennis W., Meitinger, Thomas, Strom, Tim M., Wszolek, Zbigniew K., Gasser, Thomas
Published in Neuron (Cambridge, Mass.) (18.11.2004)
Published in Neuron (Cambridge, Mass.) (18.11.2004)
Get full text
Journal Article
The Small GTPase RAC1/CED-10 Is Essential in Maintaining Dopaminergic Neuron Function and Survival Against α-Synuclein-Induced Toxicity
Kim, Hanna, Calatayud, Carles, Guha, Sanjib, Fernández-Carasa, Irene, Berkowitz, Laura, Carballo-Carbajal, Iria, Ezquerra, Mario, Fernández-Santiago, Rubén, Kapahi, Pankaj, Raya, Ángel, Miranda-Vizuete, Antonio, Lizcano, Jose Miguel, Vila, Miquel, Caldwell, Kim A., Caldwell, Guy A., Consiglio, Antonella, Dalfo, Esther
Published in Molecular neurobiology (01.09.2018)
Published in Molecular neurobiology (01.09.2018)
Get full text
Journal Article
The E3 Ubiquitin Ligases TRIM17 and TRIM41 Modulate α-Synuclein Expression by Regulating ZSCAN21
Lassot, Iréna, Mora, Stéphan, Lesage, Suzanne, Zieba, Barbara A., Coque, Emmanuelle, Condroyer, Christel, Bossowski, Jozef Piotr, Mojsa, Barbara, Marelli, Cecilia, Soulet, Caroline, Tesson, Christelle, Carballo-Carbajal, Iria, Laguna, Ariadna, Mangone, Graziella, Vila, Miquel, Brice, Alexis, Desagher, Solange
Published in Cell reports (Cambridge) (27.11.2018)
Published in Cell reports (Cambridge) (27.11.2018)
Get full text
Journal Article
Leucine-rich repeat kinase 2 induces α-synuclein expression via the extracellular signal-regulated kinase pathway
Carballo-Carbajal, Iria, Weber-Endress, Susanne, Rovelli, Giorgio, Chan, Diane, Wolozin, Benjamin, Klein, Christian L., Patenge, Nadja, Gasser, Thomas, Kahle, Philipp J.
Published in Cellular signalling (01.05.2010)
Published in Cellular signalling (01.05.2010)
Get full text
Journal Article
Validation of a Reversed Phase UPLC-MS/MS Method to Determine Dopamine Metabolites and Oxidation Intermediates in Neuronal Differentiated SH-SY5Y Cells and Brain Tissue
Gonzalez-Sepulveda, Marta, Laguna, Ariadna, Carballo-Carbajal, Iria, Galiano-Landeira, Jordi, Romero-Gimenez, Jordi, Cuadros, Thais, Parent, Annabelle, Peñuelas, Nuria, Compte, Joan, Nicolau, Alba, Guillard-Sirieix, Camille, Xicoy, Helena, Kobayashi, Jumpei, Vila, Miquel
Published in ACS chemical neuroscience (02.09.2020)
Published in ACS chemical neuroscience (02.09.2020)
Get full text
Journal Article
Correction to: The Small GTPase RAC1/CED-10 Is Essential in Maintaining Dopaminergic Neuron Function and Survival Against α-Synuclein-Induced Toxicity
Kim, Hanna, Calatayud, Carles, Guha, Sanjib, Fernández-Carasa, Irene, Berkowitz, Laura, Carballo-Carbajal, Iria, Ezquerra, Mario, Fernández-Santiago, Rubén, Kapahi, Pankaj, Raya, Ángel, Miranda-Vizuete, Antonio, Lizcano, Jose Miguel, Vila, Miquel, Caldwell, Kim A., Caldwell, Guy A., Consiglio, Antonella, Dalfo, Esther
Published in Molecular neurobiology (01.09.2018)
Published in Molecular neurobiology (01.09.2018)
Get full text
Journal Article
Lewy body extracts from Parkinson disease brains trigger α-synuclein pathology and neurodegeneration in mice and monkeys
Recasens, Ariadna, Dehay, Benjamin, Bové, Jordi, Carballo-Carbajal, Iria, Dovero, Sandra, Pérez-Villalba, Ana, Fernagut, Pierre-Olivier, Blesa, Javier, Parent, Annabelle, Perier, Céline, Fariñas, Isabel, Obeso, José, Bézard, Erwan, Vila, Miquel
Published in Annals of neurology (01.03.2014)
Published in Annals of neurology (01.03.2014)
Get full text
Journal Article
Lewy body extracts from Parkinson disease brains trigger [alpha]-synuclein pathology and neurodegeneration in mice and monkeys
Recasens, Ariadna, Dehay, Benjamin, Bove, Jordi, Carballo-Carbajal, Iria, Dovero, Sandra, Perez-Villalba, Ana, Fernagut, Pierre-Olivier, Blesa, Javier, Parent, Annabelle, Perier, Celine, Farinas, Isabel, Obeso, José A, Bezard, Erwan, Vila, Miquel
Published in Annals of neurology (01.03.2014)
Published in Annals of neurology (01.03.2014)
Get full text
Journal Article
Leucine-rich repeat kinase 2 induces a-synuclein expression via the extracellular signal-regulated kinase pathway
Carballo-Carbajal, Iria, Weber-Endress, Susanne, Rovelli, Giorgio, Chan, Diane, Wolozin, Benjamin, Klein, Christian L, Patenge, Nadja, Gasser, Thomas, Kahle, Philipp J
Published in Cellular signalling (01.05.2010)
Published in Cellular signalling (01.05.2010)
Get full text
Journal Article