A selectable all-in-one CRISPR prime editing piggyBac transposon allows for highly efficient gene editing in human cell lines
Eggenschwiler, Reto, Gschwendtberger, Thomas, Felski, Christian, Jahn, Christopher, Langer, Florian, Sterneckert, Jared, Hermann, Andreas, Lühmann, Jonathan, Steinemann, Doris, Haase, Alexandra, Martin, Ulrich, Petri, Susanne, Cantz, Tobias
Published in Scientific reports (12.11.2021)
Published in Scientific reports (12.11.2021)
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Genome-wide tracking of dCas9-methyltransferase footprints
Galonska, Christina, Charlton, Jocelyn, Mattei, Alexandra L., Donaghey, Julie, Clement, Kendell, Gu, Hongcang, Mohammad, Arman W., Stamenova, Elena K., Cacchiarelli, Davide, Klages, Sven, Timmermann, Bernd, Cantz, Tobias, Schöler, Hans R., Gnirke, Andreas, Ziller, Michael J., Meissner, Alexander
Published in Nature communications (09.02.2018)
Published in Nature communications (09.02.2018)
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Direct conversion of porcine primary fibroblasts into hepatocyte-like cells
Fráguas-Eggenschwiler, Mariane, Eggenschwiler, Reto, Söllner, Jenny-Helena, Cortnumme, Leon, Vondran, Florian W. R., Cantz, Tobias, Ott, Michael, Niemann, Heiner
Published in Scientific reports (29.04.2021)
Published in Scientific reports (29.04.2021)
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Lentiviral Vector Design and Imaging Approaches to Visualize the Early Stages of Cellular Reprogramming
Warlich, Eva, Kuehle, Johannes, Cantz, Tobias, Brugman, Martijn H, Maetzig, Tobias, Galla, Melanie, Filipczyk, Adam A, Halle, Stephan, Klump, Hannes, Schöler, Hans R, Baum, Christopher, Schroeder, Timm, Schambach, Axel
Published in Molecular therapy (01.04.2011)
Published in Molecular therapy (01.04.2011)
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miRNA screening reveals a new miRNA family stimulating iPS cell generation via regulation of Meox2
Pfaff, Nils, Fiedler, Jan, Holzmann, Angelika, Schambach, Axel, Moritz, Thomas, Cantz, Tobias, Thum, Thomas
Published in EMBO reports (01.11.2011)
Published in EMBO reports (01.11.2011)
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MicroRNA-125b-5p mimic inhibits acute liver failure
Yang, Dakai, Yuan, Qinggong, Balakrishnan, Asha, Bantel, Heike, Klusmann, Jan-Henning, Manns, Michael P., Ott, Michael, Cantz, Tobias, Sharma, Amar Deep
Published in Nature communications (23.06.2016)
Published in Nature communications (23.06.2016)
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Protein transduction from retroviral Gag precursors
Voelkel, Christine, Galla, Melanie, Maetzig, Tobias, Warlich, Eva, Kuehle, Johannes, Zychlinski, Daniela, Bode, Juergen, Cantz, Tobias, Schambach, Axel, Baum, Christopher, Hughes, Stephen H.
Published in Proceedings of the National Academy of Sciences - PNAS (27.04.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (27.04.2010)
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Gene correction of human induced pluripotent stem cells repairs the cellular phenotype in pulmonary alveolar proteinosis
Lachmann, Nico, Happle, Christine, Ackermann, Mania, Lüttge, Doreen, Wetzke, Martin, Merkert, Sylvia, Hetzel, Miriam, Kensah, George, Jara-Avaca, Monica, Mucci, Adele, Skuljec, Jelena, Dittrich, Anna-Maria, Pfaff, Nils, Brennig, Sebastian, Schambach, Axel, Steinemann, Doris, Göhring, Gudrun, Cantz, Tobias, Martin, Ulrich, Schwerk, Nicolaus, Hansen, Gesine, Moritz, Thomas
Published in American journal of respiratory and critical care medicine (15.01.2014)
Published in American journal of respiratory and critical care medicine (15.01.2014)
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Electrophysiological Properties of Tetraploid Cardiomyocytes Derived from Murine Pluripotent Stem Cells Generated by Fusion of Adult Somatic Cells with Embryonic Stem Cells
Xu, Guoxing, Fatima, Azra, Breitbach, Martin, Kuzmenkin, Alexey, Fügemann, Christopher J, Ivanyuk, Dina, Kim, Kee Pyo, Cantz, Tobias, Pfannkuche, Kurt, Schöler, Hans R, Fleischmann, Bernd K, Hescheler, Jürgen, Šarić, Tomo
Published in International journal of molecular sciences (31.03.2023)
Published in International journal of molecular sciences (31.03.2023)
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Human germline editing in the era of CRISPR-Cas: risk and uncertainty, inter-generational responsibility, therapeutic legitimacy
Schleidgen, Sebastian, Dederer, Hans-Georg, Sgodda, Susan, Cravcisin, Stefan, Lüneburg, Luca, Cantz, Tobias, Heinemann, Thomas
Published in BMC medical ethics (11.09.2020)
Published in BMC medical ethics (11.09.2020)
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Small Molecules Facilitate Single Factor-Mediated Hepatic Reprogramming
Lim, Kyung Tae, Lee, Seung Chan, Gao, Yimeng, Kim, Kee-Pyo, Song, Guangqi, An, Su Yeon, Adachi, Kenjiro, Jang, Yu Jin, Kim, Jonghun, Oh, Kyoung-Jin, Kwak, Tae Hwan, Hwang, Seon In, You, Jueng Soo, Ko, Kinarm, Koo, Seung-Hoi, Sharma, Amar Deep, Kim, Jong-Hoon, Hui, Lijian, Cantz, Tobias, Schöler, Hans R., Han, Dong Wook
Published in Cell reports (Cambridge) (26.04.2016)
Published in Cell reports (Cambridge) (26.04.2016)
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Promoter and lineage independent anti-silencing activity of the A2 ubiquitous chromatin opening element for optimized human pluripotent stem cell-based gene therapy
Ackermann, Mania, Lachmann, Nico, Hartung, Susann, Eggenschwiler, Reto, Pfaff, Nils, Happle, Christine, Mucci, Adele, Göhring, Gudrun, Niemann, Heiner, Hansen, Gesine, Schambach, Axel, Cantz, Tobias, Zweigerdt, Robert, Moritz, Thomas
Published in Biomaterials (01.02.2014)
Published in Biomaterials (01.02.2014)
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A combined in silico and in vitro study on mouse Serpina1a antitrypsin-deficiency mutants
Eggenschwiler, Reto, Patronov, Atanas, Hegermann, Jan, Fráguas-Eggenschwiler, Mariane, Wu, Guangming, Cortnumme, Leon, Ochs, Matthias, Antes, Iris, Cantz, Tobias
Published in Scientific reports (16.05.2019)
Published in Scientific reports (16.05.2019)
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MicroRNA-199a-5p inhibition enhances the liver repopulation ability of human embryonic stem cell-derived hepatic cells
Möbus, Selina, Yang, Dakai, Yuan, Qinggong, Lüdtke, Timo H.-W, Balakrishnan, Asha, Sgodda, Malte, Rani, Bhavna, Kispert, Andreas, Araúzo-Bravo, Marcos J, Vogel, Arndt, Manns, Michael P, Ott, Michael, Cantz, Tobias, Sharma, Amar Deep
Published in Journal of hepatology (01.01.2015)
Published in Journal of hepatology (01.01.2015)
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Absence of OCT4 Expression in Somatic Tumor Cell Lines
Cantz, Tobias, Key, Göran, Bleidiβel, Martina, Gentile, Luca, Han, Dong Wook, Brenne, Alexandra, Schöler, Hans R.
Published in Stem cells (Dayton, Ohio) (01.03.2008)
Published in Stem cells (Dayton, Ohio) (01.03.2008)
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Generation of integration-free induced hepatocyte-like cells from mouse fibroblasts
Kim, Jonghun, Kim, Kee-Pyo, Lim, Kyung Tae, Lee, Seung Chan, Yoon, Juyong, Song, Guangqi, Hwang, Seon In, Schöler, Hans R., Cantz, Tobias, Han, Dong Wook
Published in Scientific reports (27.10.2015)
Published in Scientific reports (27.10.2015)
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