Beneficial and Adverse Effects of an LXR Agonist on Human Lipid and Lipoprotein Metabolism and Circulating Neutrophils
Kirchgessner, Todd G., Sleph, Paul, Ostrowski, Jacek, Lupisella, John, Ryan, Carol S., Liu, Xiaoqin, Fernando, Gayani, Grimm, Denise, Shipkova, Petia, Zhang, Rongan, Garcia, Ricardo, Zhu, Jun, He, Aiqing, Malone, Harold, Martin, Richard, Behnia, Kamelia, Wang, Zhaoqing, Barrett, Yu Chen, Garmise, Robert J., Yuan, Long, Zhang, Jane, Gandhi, Mohit D., Wastall, Philip, Li, Tong, Du, Shuyan, Salvador, Lisa, Mohan, Raju, Cantor, Glenn H., Kick, Ellen, Lee, John, Frost, Robert J.A.
Published in Cell metabolism (09.08.2016)
Published in Cell metabolism (09.08.2016)
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BMS-754807, a small molecule inhibitor of insulin-like growth factor-1R/IR
Carboni, Joan M, Wittman, Mark, Yang, Zheng, Lee, Francis, Greer, Ann, Hurlburt, Warren, Hillerman, Stephen, Cao, Carolyn, Cantor, Glenn H, Dell-John, Janet, Chen, Cliff, Discenza, Lorell, Menard, Krista, Li, Aixin, Trainor, George, Vyas, Dolatrai, Kramer, Robert, Attar, Ricardo M, Gottardis, Marco M
Published in Molecular cancer therapeutics (01.12.2009)
Published in Molecular cancer therapeutics (01.12.2009)
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Metabonomics evaluation of urine from rats given acute and chronic doses of acetaminophen using NMR and UPLC/MS
Sun, Jinchun, Schnackenberg, Laura K., Holland, Ricky D., Schmitt, Thomas C., Cantor, Glenn H., Dragan, Yvonne P., Beger, Richard D.
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (15.08.2008)
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (15.08.2008)
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Bacterial- and Viral-Induced Inflammation Increases Sensitivity to Acetaminophen Hepatotoxicity
Maddox, Jane F., Amuzie, Chidozie J., Li, Maoxiang, Newport, Sandra W., Sparkenbaugh, Erica, Cuff, Christopher F., Pestka, James J., Cantor, Glenn H., Roth, Robert A., Ganey, Patricia E.
Published in Journal of Toxicology and Environmental Health, Part A (01.01.2010)
Published in Journal of Toxicology and Environmental Health, Part A (01.01.2010)
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Comparative metabonomics of differential hydrazine toxicity in the rat and mouse
Bollard, Mary E., Keun, Hector C., Beckonert, Olaf, Ebbels, Tim M.D., Antti, Henrik, Nicholls, Andrew W., Shockcor, John P., Cantor, Glenn H., Stevens, Greg, Lindon, John C., Holmes, Elaine, Nicholson, Jeremy K.
Published in Toxicology and applied pharmacology (15.04.2005)
Published in Toxicology and applied pharmacology (15.04.2005)
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Tissue factor contributes to neutrophil CD11b expression in alpha-naphthylisothiocyanate-treated mice
Luyendyk, James P., Flanagan, Kevin C., Williams, C. David, Jaeschke, Hartmut, Slusser, Joyce G., Mackman, Nigel, Cantor, Glenn H.
Published in Toxicology and applied pharmacology (01.02.2011)
Published in Toxicology and applied pharmacology (01.02.2011)
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Discovery and structure activity relationships of 7-benzyl triazolopyridines as stable, selective, and reversible inhibitors of myeloperoxidase
Shaw, Scott A., Vokits, Benjamin P., Dilger, Andrew K., Viet, Andrew, Clark, Charles G., Abell, Lynn M., Locke, Gregory A., Duke, Gerald, Kopcho, Lisa M., Dongre, Ashok, Gao, Ji, Krishnakumar, Arathi, Jusuf, Sutjano, Khan, Javed, Spronk, Steven A., Basso, Michael D., Zhao, Lei, Cantor, Glenn H., Onorato, Joelle M., Wexler, Ruth R., Duclos, Franck, Kick, Ellen K.
Published in Bioorganic & medicinal chemistry (15.11.2020)
Published in Bioorganic & medicinal chemistry (15.11.2020)
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Pharmacological characterization of a novel liver X receptor agonist with partial LXRα activity and a favorable window in nonhuman primates
Kirchgessner, Todd G, Martin, Richard, Sleph, Paul, Grimm, Denise, Liu, Xiaoqin, Lupisella, John, Smalley, James, Narayanan, Rangaraj, Xie, Yinong, Ostrowski, Jacek, Cantor, Glenn H, Mohan, Raju, Kick, Ellen
Published in The Journal of pharmacology and experimental therapeutics (01.02.2015)
Published in The Journal of pharmacology and experimental therapeutics (01.02.2015)
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Coagulation-Dependent Gene Expression and Liver Injury in Rats Given Lipopolysaccharide with Ranitidine but Not with Famotidine
Luyendyk, James P, Lehman-McKeeman, Lois D, Nelson, David M, Bhaskaran, Vasanthi M, Reilly, Timothy P, Car, Bruce D, Cantor, Glenn H, Deng, Xiaomin, Maddox, Jane F, Ganey, Patricia E, Roth, Robert A
Published in The Journal of pharmacology and experimental therapeutics (01.05.2006)
Published in The Journal of pharmacology and experimental therapeutics (01.05.2006)
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Hepatitis C Virus NS5A Replication Complex Inhibitors: The Discovery of Daclatasvir
Belema, Makonen, Nguyen, Van N., Bachand, Carol, Deon, Dan H., Goodrich, Jason T., James, Clint A., Lavoie, Rico, Lopez, Omar D., Martel, Alain, Romine, Jeffrey L., Ruediger, Edward H., Snyder, Lawrence B., Laurent, Denis R. St, Yang, Fukang, Zhu, Juliang, Wong, Henry S., Langley, David R., Adams, Stephen P., Cantor, Glenn H., Chimalakonda, Anjaneya, Fura, Aberra, Johnson, Benjamin M., Knipe, Jay O., Parker, Dawn D., Santone, Kenneth S., Fridell, Robert A., Lemm, Julie A., O’Boyle, Donald R., Colonno, Richard J., Gao, Min, Meanwell, Nicholas A., Hamann, Lawrence G.
Published in Journal of medicinal chemistry (13.03.2014)
Published in Journal of medicinal chemistry (13.03.2014)
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Discovery of (R)-N-(3-(7-methyl-1H-indazol-5-yl)-1-(4-(1-methylpiperidin-4-yl)-1-oxopropan-2-yl)-4-(2-oxo-1,2-dihydroquinolin-3-yl)piperidine-1-carboxamide (BMS-742413): A potent human CGRP antagonist with superior safety profile for the treatment of migraine through intranasal delivery
Chaturvedula, Prasad V., Mercer, Stephen E., Pin, Sokhom S., Thalody, George, Xu, Cen, Conway, Charlie M., Keavy, Deborah, Signor, Laura, Cantor, Glenn H., Mathias, Neil, Moench, Paul, Denton, Rex, Macci, Robert, Schartman, Richard, Whiterock, Valerie, Davis, Carl, Macor, John E., Dubowchik, Gene M.
Published in Bioorganic & medicinal chemistry letters (01.06.2013)
Published in Bioorganic & medicinal chemistry letters (01.06.2013)
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NMR-Based Metabolic Profiling Identifies Biomarkers of Liver Regeneration Following Partial Hepatectomy in the Rat
Bollard, Mary E, Contel, Nancy R, Ebbels, Timothy M. D, Smith, Leon, Beckonert, Olaf, Cantor, Glenn H, Lehman-McKeeman, Lois, Holmes, Elaine C, Lindon, John C, Nicholson, Jeremy K, Keun, Hector C
Published in Journal of proteome research (04.01.2010)
Published in Journal of proteome research (04.01.2010)
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Fibrinogen Deficiency Increases Liver Injury and Early Growth Response-1 (Egr-1) Expression in a Model of Chronic Xenobiotic-Induced Cholestasis
Luyendyk, James P, Kassel, Karen M, Allen, Katryn, Guo, Grace L, Li, Guodong, Cantor, Glenn H, Copple, Bryan L
Published in The American journal of pathology (01.03.2011)
Published in The American journal of pathology (01.03.2011)
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Systemic Loss of C-terminal Src Kinase Expression Elicits Spontaneous Suppurative Inflammation in Conditional Knockout Mice
Berman-Booty, Lisa D., Eraslan, Rukiye, Hanumegowda, Umesh, Cantor, Glenn H., Bounous, Denise I., Janovitz, Evan B., Jones, Beverly K., Buiakova, Olesia, Hayward, Michael, Wee, Susan
Published in Veterinary pathology (01.03.2018)
Published in Veterinary pathology (01.03.2018)
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Summary recommendations for standardization and reporting of metabolic analyses
Lindon, John C, Nicholson, Jeremy K, Holmes, Elaine, Keun, Hector C, Craig, Andrew, Pearce, Jake T M, Bruce, Stephen J, Hardy, Nigel, Sansone, Susanna-Assunta, Antti, Henrik, Jonsson, Par, Daykin, Clare, Navarange, Mahendra, Beger, Richard D, Verheij, Elwin R, Amberg, Alexander, Baunsgaard, Dorrit, Cantor, Glenn H, Lehman-McKeeman, Lois, Earll, Mark, Wold, Svante, Johansson, Erik, Haselden, John N, Kramer, Kerstin, Thomas, Craig, Lindberg, Johann, Schuppe-Koistinen, Ina, Wilson, Ian D, Reily, Michael D, Robertson, Donald G, Senn, Hans, Krotzky, Arno, Kochhar, Sunil, Powell, Jonathan, van der Ouderaa, Frans, Plumb, Robert, Schaefer, Hartmut, Spraul, Manfred
Published in Nature biotechnology (01.07.2005)
Published in Nature biotechnology (01.07.2005)
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Tissue factor-dependent coagulation contributes to alpha-naphthylisothiocyanate-induced cholestatic liver injury in mice
Luyendyk, James P, Cantor, Glenn H, Kirchhofer, Daniel, Mackman, Nigel, Copple, Bryan L, Wang, Ruipeng
Published in American journal of physiology: Gastrointestinal and liver physiology (01.04.2009)
Published in American journal of physiology: Gastrointestinal and liver physiology (01.04.2009)
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Insulin Receptor (IR) Pathway Hyperactivity in IGF-IR Null Cells and Suppression of Downstream Growth Signaling Using the Dual IGF-IR/IR Inhibitor, BMS-754807
Dinchuk, Joseph E, Cao, Carolyn, Huang, Fei, Reeves, Karen A, Wang, Jeanne, Myers, Fanny, Cantor, Glenn H, Zhou, Xiadi, Attar, Ricardo M, Gottardis, Marco, Carboni, Joan M
Published in Endocrinology (Philadelphia) (01.09.2010)
Published in Endocrinology (Philadelphia) (01.09.2010)
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Discovery of Highly Potent Liver X Receptor β Agonists
Kick, Ellen K, Busch, Brett B, Martin, Richard, Stevens, William C, Bollu, Venkataiah, Xie, Yinong, Boren, Brant C, Nyman, Michael C, Nanao, Max H, Nguyen, Lam, Plonowski, Artur, Schulman, Ira G, Yan, Grace, Zhang, Huiping, Hou, Xiaoping, Valente, Meriah N, Narayanan, Rangaraj, Behnia, Kamelia, Rodrigues, A. David, Brock, Barry, Smalley, James, Cantor, Glenn H, Lupisella, John, Sleph, Paul, Grimm, Denise, Ostrowski, Jacek, Wexler, Ruth R, Kirchgessner, Todd, Mohan, Raju
Published in ACS medicinal chemistry letters (08.12.2016)
Published in ACS medicinal chemistry letters (08.12.2016)
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