Process Development for a Large Scale Stereoselective Synthesis of (Z)-(1-Bromobut-1-ene-1,2-diyl)dibenzene, a Key Intermediate of a Selective Estrogen Receptor Modulator
Cann, Reginald O, Waltermire, Robert E, Chung, Jihchin, Oberholzer, Matthew, Kasparec, Jiri, Ye, Yun K, Wethman, Robert
Published in Organic process research & development (17.09.2010)
Published in Organic process research & development (17.09.2010)
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Journal Article
Selection of an Enantioselective Process for the Preparation of a CGRP Receptor Inhibitor
Cann, Reginald O, Chen, Chung-Pin H, Gao, Qi, Hanson, Ronald L, Hsieh, Daniel, Li, Jun, Lin, Dong, Parsons, Rodney L, Pendri, Yadagiri, Nielsen, R. Brent, Nugent, William A, Parker, William L, Quinlan, Sandra, Reising, Nathan P, Remy, Brenda, Sausker, Justin, Wang, Xuebao
Published in Organic process research & development (21.12.2012)
Published in Organic process research & development (21.12.2012)
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Journal Article
Enynones in Organic Synthesis. 7. Substituent Effects on the .alpha.-Tocopherol-Catalyzed Cyclization of Enynones to Methylenecyclopentenones. Convenient Syntheses of Members of the Methylenomycin Class of Antibiotics
Jacobi, Peter A, Brielmann, Harry L, Cann, Reginald O
Published in Journal of organic chemistry (01.09.1994)
Published in Journal of organic chemistry (01.09.1994)
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Journal Article
Zwitterionic Sulfobetaine Inhibitors of Squalene Synthase
Spencer, Thomas A, Onofrey, Thomas J, Cann, Reginald O, Russel, Jonathon S, Lee, Laura E, Blanchard, Daniel E, Castro, Alfredo, Gu, Peide, Jiang, Guojian, Shechter, Ishaiahu
Published in Journal of organic chemistry (05.02.1999)
Published in Journal of organic chemistry (05.02.1999)
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Journal Article
TRIAZOLOPYRIDINE 11-BETA HYDROXYSTEROID DEHYDROGENASE TYPE I INHIBITORS
DESHPANDE RAJENDRA P, WEI CHENKOU, ROBL JEFFREY A, LI JAMES J, LI JUN, CANN REGINALD O, KENNEDY LAWRENCE J, LI JIE JACK, QIAN XINHUA, KOLLA LAXMA R, WANG HAIXIA, GALELLA MICHAEL
Year of Publication 28.07.2010
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Year of Publication 28.07.2010
Patent
Enynones in Organic Synthesis. 6. Synthesis of Spirocyclic Methylenecyclopentenones and Analogs of the Methylenomycin Class of Antibiotics. Mechanism of Phenol Catalysis
Jacobi, Peter A, Armacost, Lisa M, Brielmann, Harry L, Cann, Reginald O, Kravitz, Joseph I, Martinelli, Michael J
Published in Journal of organic chemistry (01.09.1994)
Published in Journal of organic chemistry (01.09.1994)
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Journal Article
Synthesis of unsymmetric cyclic urea diols, a novel class of HIV protease inhibitors
Stone, Benjamin R.P., Harris, Gregory D., Cann, Reginald O., Smyser, Thomas E., Confalone, Pat N.
Published in Tetrahedron letters (20.08.1998)
Published in Tetrahedron letters (20.08.1998)
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Journal Article
Sulfobetaine zwitterionic inhibitors of squalene synthase
Shechter, Ishaiahu, Gu, Peide, Jiang, Guojian, Onofrey, Thomas J., Cann, Reginald O., Castro, Alfredo, Spencer, Thomas A.
Published in Bioorganic & medicinal chemistry letters (05.11.1996)
Published in Bioorganic & medicinal chemistry letters (05.11.1996)
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Journal Article
ChemInform Abstract: Asymmetric Hydrogenation of an Amino Acid Intermediate in the Synthesis of Complex Drug Targets: from Kinetic Modeling to Process Development
Hsieh, Daniel S., Lin, Dong, Wang, Steve S. Y., Cann, Reginald O., Sausker, Justin B., Kiang, San
Published in ChemInform (25.05.2010)
Published in ChemInform (25.05.2010)
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Journal Article
Triazolopyridine 11-beta hydroxysteroid dehydrogenase type I inhibitors
DESHPANDE, RAJENDRA P, WANG, HAIXIA, LI, JIE JACK, QIAN, XINHUA, ROBL, JEFFREY A, GALELLA, MICHAEL, KENNEDY, LAWRENCE J, KOLLA, LAXMA R, WEI, CHENKOU, CANN, REGINALD O, LI, JAMES J, LI, JUN
Year of Publication 12.12.2013
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Year of Publication 12.12.2013
Patent
TRIAZOLOPYRIDINE 11-BETA HYDROXYSTEROID DEHYDROGENASE TYPE I INHIBITORS
WANG, HAIXIA, LI, JIE JACK, DESHPANDE, RAJENDRA P, QIAN, XINHUA, ROBL, JEFFREY A, GALELLA, MICHAEL, KENNEDY, LAWRENCE J, KOLLA, LAXMA R, WEI, CHENKOU, CANN, REGINALD O, LI, JAMES J, LI, JUN
Year of Publication 28.06.2013
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Year of Publication 28.06.2013
Patent
Triazolopyridine 11-beta hydroxysteroid dehydrogenase type I inhibitors
DESHPANDE RAJENDRA P, WEI CHENKOU, ROBL JEFFREY A, LI JAMES J, LI JUN, CANN REGINALD O, KENNEDY LAWRENCE J, LI JIE JACK, QIAN XINHUA, KOLLA LAXMA R, WANG HAIXIA, GALELLA MICHAEL
Year of Publication 21.02.2012
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Year of Publication 21.02.2012
Patent
Triazolopyridine 11-beta hydroxysteroid dehydrogenase type I inhibitors
Li, Jun, Robl, Jeffrey A, Li, James J, Kennedy, Lawrence J, Wang, Haixia, Li, Jie Jack, Qian, Xinhua, Deshpande, Rajendra P, Kolla, Laxma R, Cann, Reginald O, Wei, Chenkou, Galella, Michael
Year of Publication 21.02.2012
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Year of Publication 21.02.2012
Patent
TRIAZOLOPYRIDINE 11-BETA HYDROXYSTEROID DEHYDROGENASE TYPE I INHIBITORS
WEI CHENKOU, ROBL JEFFREY A, LI JAMES J, LI JUN, CANN REGINALD O, DESPANDE RAJENDRA P, LI JIE JACK, QIAN XINHUA, KOLLA LAXMA R, KENNEDY LAWERENCE J, WANG HAIXIA, GALELLA MICHAEL
Year of Publication 25.05.2011
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Year of Publication 25.05.2011
Patent
Specific salt forms of triphenylethylene derivatives as selective estrogen receptor modulators
DENETTE K. MURPHY, REGINALD O. CANN, CHRISTOPHER A. TELEHA, GARY A. CAIN
Year of Publication 02.03.2006
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Year of Publication 02.03.2006
Patent