Bridging Disulfides for Stable and Defined Antibody Drug Conjugates
Badescu, George, Bryant, Penny, Bird, Matthew, Henseleit, Korinna, Swierkosz, Julia, Parekh, Vimal, Tommasi, Rita, Pawlisz, Estera, Jurlewicz, Kosma, Farys, Monika, Camper, Nicolas, Sheng, XiaoBo, Fisher, Martin, Grygorash, Ruslan, Kyle, Andrew, Abhilash, Amrita, Frigerio, Mark, Edwards, Jeff, Godwin, Antony
Published in Bioconjugate chemistry (18.06.2014)
Published in Bioconjugate chemistry (18.06.2014)
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Journal Article
Incorporation of Hydrophilic Macrocycles Into Drug-Linker Reagents Produces Antibody-Drug Conjugates With Enhanced in vivo Performance
Evans, Nick, Grygorash, Ruslan, Williams, Paul, Kyle, Andrew, Kantner, Terrence, Pathak, Ravindra, Sheng, XiaoBo, Simoes, Fabio, Makwana, Hiteshri, Resende, Ricardo, de Juan, Elena, Jenkins, Alan, Morris, David, Michelet, Aurelie, Jewitt, Frances, Rudge, Felicity, Camper, Nicolas, Manin, Anaïs, McDowell, William, Pabst, Martin, Godwin, Antony, Frigerio, Mark, Bird, Matthew
Published in Frontiers in pharmacology (17.06.2022)
Published in Frontiers in pharmacology (17.06.2022)
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A role for whey acidic protein four-disulfide-core 12 (WFDC12) in the regulation of the inflammatory response in the lung
Glasgow, Arlene M A, Small, Donna M, Scott, Aaron, McLean, Denise T, Camper, Nicolas, Hamid, Umar, Hegarty, Shauna, Parekh, Dhruv, O'Kane, Cecilia, Lundy, Fionnuala T, McNally, Paul, Elborn, J Stuart, McAuley, Danny F, Weldon, Sinéad, Taggart, Clifford C
Published in Thorax (01.05.2015)
Published in Thorax (01.05.2015)
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Journal Article
Targeted delivery of alcohol-containing payloads with antibody-drug conjugates
Grier, Katja E, Hansen, Anders H, Haxvig, Christina S, Li, Xin, Krigslund, Oliver, Behrendt, Niels, Engelholm, Lars H, Rossi, Fabio, Sousa, Bebiana C, Harradence, Grant J, Camper, Nicolas, Qvortrup, Katrine M
Published in Chemical communications (Cambridge, England) (08.06.2023)
Published in Chemical communications (Cambridge, England) (08.06.2023)
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Journal Article
In Vitro and In Vivo Evaluation of Cysteine Rebridged Trastuzumab–MMAE Antibody Drug Conjugates with Defined Drug-to-Antibody Ratios
Bryant, Penny, Pabst, Martin, Badescu, George, Bird, Matthew, McDowell, William, Jamieson, Estera, Swierkosz, Julia, Jurlewicz, Kosma, Tommasi, Rita, Henseleit, Korinna, Sheng, XiaoBo, Camper, Nicolas, Manin, Anais, Kozakowska, Katarzyna, Peciak, Karolina, Laurine, Emmanuelle, Grygorash, Ruslan, Kyle, Andrew, Morris, David, Parekh, Vimal, Abhilash, Amrita, Choi, Ji-won, Edwards, Jeff, Frigerio, Mark, Baker, Matthew P, Godwin, Antony
Published in Molecular pharmaceutics (01.06.2015)
Published in Molecular pharmaceutics (01.06.2015)
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Journal Article
항체-약물 접합체
SIM NEIL, FLEMING JAMES, OUBERAI MYRIAM, CAMPER NICOLAS, FRIGERIO MARK
Year of Publication 03.02.2023
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Year of Publication 03.02.2023
Patent
Modulation of drug-linker design to enhance in vivo potency of homogeneous antibody-drug conjugates
Pabst, Martin, McDowell, William, Manin, Anaïs, Kyle, Andrew, Camper, Nicolas, De Juan, Elena, Parekh, Vimal, Rudge, Felicity, Makwana, Hiteshri, Kantner, Terrence, Parekh, Hemal, Michelet, Aurelie, Sheng, XiaoBo, Popa, Gina, Tucker, Carolyn, Khayrzad, Farzad, Pollard, Derek, Kozakowska, Katarzyna, Resende, Ricardo, Jenkins, Alan, Simoes, Fabio, Morris, Dave, Williams, Paul, Badescu, George, Baker, Matthew P., Bird, Matthew, Frigerio, Mark, Godwin, Antony
Published in Journal of controlled release (10.05.2017)
Published in Journal of controlled release (10.05.2017)
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Journal Article
Abstract 1779: Anti-Müllerian hormone type II receptor (AMHRII), a cancer target for GM103, a novel antibody-drug conjugate (ADC)
Dubreuil, Olivier, Barret, Jean-Marc M., Mohan, Raghav, Pugnière, Martine, Pepin, David, Desigaud, Delphine, McDowell, William, Manin, Anaïs, Camper, Nicolas, Nicolas, André, Donahoe, Patricia K., Prost, Jean-François F.
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Synthesis of an analogue of the bisphosphonate drug Ibandronate for targeted drug-delivery therapeutic strategiesThis article is part of a themed issue on Biophosphates.Electronic supplementary information (ESI) available: NMR data for compounds 1 and 3. See DOI: 10.1039/b9nj00597h
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Stable expression and purification of a functional processed Fab′ fragment from a single nascent polypeptide in CHO cells expressing the mCAT-1 retroviral receptor
Camper, Nicolas, Byrne, Teresa, Burden, Roberta E., Lowry, Jenny, Gray, Breena, Johnston, James A., Migaud, Marie E., Olwill, Shane A., Buick, Richard J., Scott, Christopher J.
Published in Journal of immunological methods (30.09.2011)
Published in Journal of immunological methods (30.09.2011)
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Journal Article
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Year of Publication 31.07.2024
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Year of Publication 31.07.2024
Patent
ANTIBODY-DRUG CONJUGATES
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Year of Publication 08.06.2023
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Year of Publication 08.06.2023
Patent
ANTIBODY-DRUG CONJUGATES
FLEMING, James, SIM, Neil, OUBERAI, Myriam, CAMPER, Nicolas, FRIGERIO, Mark
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Year of Publication 05.04.2023
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ANTIBODY-DRUG CONJUGATES
FLEMING, James, SIM, Neil, OUBERAI, Myriam, CAMPER, Nicolas, FRIGERIO, Mark
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Year of Publication 30.03.2023
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Antibody-drug conjugates
FLEMING, James, SIM, Neil, OUBERAI, Myriam, CAMPER, Nicolas, FRIGERIO, Mark
Year of Publication 17.11.2022
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Year of Publication 17.11.2022
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Antibody-drug conjugates
Mark Frigerio, Nicolas Camper, Neil Sim, Myriam Ouberai, James Fleming
Year of Publication 18.05.2022
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Year of Publication 18.05.2022
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ANTIBODY-DRUG CONJUGATES
SIM, NEIL, CAMPER, NICOLAS, OUBERAI, MYRIAM, FLEMING, JAMES, FRIGERIO, MARK
Year of Publication 02.12.2021
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Year of Publication 02.12.2021
Patent
ANTIBODY-DRUG CONJUGATES
FLEMING, James, SIM, Neil, OUBERAI, Myriam, CAMPER, Nicolas, FRIGERIO, Mark
Year of Publication 02.12.2021
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Year of Publication 02.12.2021
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Antibody-drug conjugates
Mark Frigerio, Nicolas Camper, Neil Sim, Myriam Ouberai, James Fleming
Year of Publication 10.11.2021
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Year of Publication 10.11.2021
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