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Published in Cell (17.09.2020)
Published in Cell (17.09.2020)
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Structures of an RNA polymerase promoter melting intermediate elucidate DNA unwinding
Boyaci, Hande, Chen, James, Jansen, Rolf, Darst, Seth A., Campbell, Elizabeth A.
Published in Nature (London) (01.01.2019)
Published in Nature (London) (01.01.2019)
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Publisher Correction: Molnupiravir: coding for catastrophe
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Published in Nature structural & molecular biology (01.11.2021)
Published in Nature structural & molecular biology (01.11.2021)
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Basis of narrow-spectrum activity of fidaxomicin on Clostridioides difficile
Cao, Xinyun, Boyaci, Hande, Chen, James, Bao, Yu, Landick, Robert, Campbell, Elizabeth A.
Published in Nature (London) (21.04.2022)
Published in Nature (London) (21.04.2022)
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Structural mechanism of transcription inhibition by lasso peptides microcin J25 and capistruin
Braffman, Nathaniel R., Piscotta, Frank J., Hauver, Jesse, Campbell, Elizabeth A., Link, A. James, Darst, Seth A.
Published in Proceedings of the National Academy of Sciences - PNAS (22.01.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (22.01.2019)
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Structural basis for backtracking by the SARS-CoV-2 replication–transcription complex
Malone, Brandon, Chen, James, Wang, Qi, Llewellyn, Eliza, Choi, Young Joo, Olinares, Paul Dominic B., Cao, Xinyun, Hernandez, Carolina, Eng, Edward T., Chait, Brian T., Shaw, David E., Landick, Robert, Darst, Seth A., Campbell, Elizabeth A.
Published in Proceedings of the National Academy of Sciences - PNAS (11.05.2021)
Published in Proceedings of the National Academy of Sciences - PNAS (11.05.2021)
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Structure and function of the mycobacterial transcription initiation complex with the essential regulator RbpA
Hubin, Elizabeth A, Fay, Allison, Xu, Catherine, Bean, James M, Saecker, Ruth M, Glickman, Michael S, Darst, Seth A, Campbell, Elizabeth A
Published in eLife (09.01.2017)
Published in eLife (09.01.2017)
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Structural basis of transcription arrest by coliphage HK022 Nun in an Escherichia coli RNA polymerase elongation complex
Kang, Jin Young, Olinares, Paul Dominic B, Chen, James, Campbell, Elizabeth A, Mustaev, Arkady, Chait, Brian T, Gottesman, Max E, Darst, Seth A
Published in eLife (20.03.2017)
Published in eLife (20.03.2017)
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E. coli TraR allosterically regulates transcription initiation by altering RNA polymerase conformation
Chen, James, Gopalkrishnan, Saumya, Chiu, Courtney, Chen, Albert Y, Campbell, Elizabeth A, Gourse, Richard L, Ross, Wilma, Darst, Seth A
Published in eLife (16.12.2019)
Published in eLife (16.12.2019)
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Structural basis for substrate selection by the SARS-CoV-2 replicase
Malone, Brandon F., Perry, Jason K., Olinares, Paul Dominic B., Lee, Hery W., Chen, James, Appleby, Todd C., Feng, Joy Y., Bilello, John P., Ng, Honkit, Sotiris, Johanna, Ebrahim, Mark, Chua, Eugene Y. D., Mendez, Joshua H., Eng, Ed T., Landick, Robert, Götte, Matthias, Chait, Brian T., Campbell, Elizabeth A., Darst, Seth A.
Published in Nature (London) (23.02.2023)
Published in Nature (London) (23.02.2023)
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Fidaxomicin jams Mycobacterium tuberculosis RNA polymerase motions needed for initiation via RbpA contacts
Boyaci, Hande, Chen, James, Lilic, Mirjana, Palka, Margaret, Mooney, Rachel Anne, Landick, Robert, Darst, Seth A, Campbell, Elizabeth A
Published in eLife (26.02.2018)
Published in eLife (26.02.2018)
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Structural basis for transcription complex disruption by the Mfd translocase
Kang, Jin Young, Llewellyn, Eliza, Chen, James, Olinares, Paul Dominic B, Brewer, Joshua, Chait, Brian T, Campbell, Elizabeth A, Darst, Seth A
Published in eLife (22.01.2021)
Published in eLife (22.01.2021)
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Rifamycin congeners kanglemycins are active against rifampicin-resistant bacteria via a distinct mechanism
Peek, James, Lilic, Mirjana, Montiel, Daniel, Milshteyn, Aleksandr, Woodworth, Ian, Biggins, John B., Ternei, Melinda A., Calle, Paula Y., Danziger, Michael, Warrier, Thulasi, Saito, Kohta, Braffman, Nathaniel, Fay, Allison, Glickman, Michael S., Darst, Seth A., Campbell, Elizabeth A., Brady, Sean F.
Published in Nature communications (08.10.2018)
Published in Nature communications (08.10.2018)
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Molnupiravir: coding for catastrophe
Malone, Brandon, Campbell, Elizabeth A.
Published in Nature structural & molecular biology (01.09.2021)
Published in Nature structural & molecular biology (01.09.2021)
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CarD uses a minor groove wedge mechanism to stabilize the RNA polymerase open promoter complex
Bae, Brian, Chen, James, Davis, Elizabeth, Leon, Katherine, Darst, Seth A, Campbell, Elizabeth A
Published in eLife (08.09.2015)
Published in eLife (08.09.2015)
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Structure and function of CarD, an essential mycobacterial transcription factor
Srivastava, Devendra B., Leon, Katherine, Osmundson, Joseph, Garner, Ashley L., Weiss, Leslie A., Westblade, Lars F., Glickman, Michael S., Landick, Robert, Darst, Seth A., Stallings, Christina L., Campbell, Elizabeth A.
Published in Proceedings of the National Academy of Sciences - PNAS (30.07.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (30.07.2013)
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Structural, functional, and genetic analyses of the actinobacterial transcription factor RbpA
Hubin, Elizabeth A., Tabib-Salazar, Aline, Humphrey, Laurence J., Flack, Joshua E., Olinares, Paul Dominic B., Darst, Seth A., Campbell, Elizabeth A., Paget, Mark S.
Published in Proceedings of the National Academy of Sciences - PNAS (09.06.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (09.06.2015)
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