K29-Selective Ubiquitin Binding Domain Reveals Structural Basis of Specificity and Heterotypic Nature of K29 Polyubiquitin
Kristariyanto, Yosua Adi, Abdul Rehman, Syed Arif, Campbell, David G., Morrice, Nicholas A., Johnson, Clare, Toth, Rachel, Kulathu, Yogesh
Published in Molecular cell (02.04.2015)
Published in Molecular cell (02.04.2015)
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The WNK-regulated SPAK/OSR1 kinases directly phosphorylate and inhibit the K+-Cl- co-transporters
de Los Heros, Paola, Alessi, Dario R, Gourlay, Robert, Campbell, David G, Deak, Maria, Macartney, Thomas J, Kahle, Kristopher T, Zhang, Jinwei
Published in Biochemical journal (15.03.2014)
Published in Biochemical journal (15.03.2014)
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Bioinformatic and experimental survey of 14-3-3-binding sites
Johnson, Catherine, Crowther, Sandra, Stafford, Margaret J, Campbell, David G, Toth, Rachel, MacKintosh, Carol
Published in Biochemical journal (15.03.2010)
Published in Biochemical journal (15.03.2010)
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The anti-inflammatory drug BAY 11-7082 suppresses the MyD88-dependent signalling network by targeting the ubiquitin system
Strickson, Sam, Campbell, David G, Emmerich, Christoph H, Knebel, Axel, Plater, Lorna, Ritorto, Maria Stella, Shpiro, Natalia, Cohen, Philip
Published in Biochemical journal (01.05.2013)
Published in Biochemical journal (01.05.2013)
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14-3-3 binding to LRRK2 is disrupted by multiple Parkinson's disease-associated mutations and regulates cytoplasmic localization
Nichols, R Jeremy, Dzamko, Nicolas, Morrice, Nicholas A, Campbell, David G, Deak, Maria, Ordureau, Alban, Macartney, Thomas, Tong, Youren, Shen, Jie, Prescott, Alan R, Alessi, Dario R
Published in Biochemical journal (15.09.2010)
Published in Biochemical journal (15.09.2010)
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PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65
Kondapalli, Chandana, Kazlauskaite, Agne, Zhang, Ning, Woodroof, Helen I., Campbell, David G., Gourlay, Robert, Burchell, Lynn, Walden, Helen, Macartney, Thomas J., Deak, Maria, Knebel, Axel, Alessi, Dario R., Muqit, Miratul M. K.
Published in Open biology (01.05.2012)
Published in Open biology (01.05.2012)
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LRRK2 phosphorylates moesin at threonine-558: characterization of how Parkinson's disease mutants affect kinase activity
Jaleel, Mahaboobi, Nichols, R Jeremy, Deak, Maria, Campbell, David G, Gillardon, Frank, Knebel, Axel, Alessi, Dario R
Published in Biochemical journal (15.07.2007)
Published in Biochemical journal (15.07.2007)
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Phosphoproteomic screening identifies Rab GTPases as novel downstream targets of PINK1
Lai, Yu-Chiang, Kondapalli, Chandana, Lehneck, Ronny, Procter, James B, Dill, Brian D, Woodroof, Helen I, Gourlay, Robert, Peggie, Mark, Macartney, Thomas J, Corti, Olga, Corvol, Jean-Christophe, Campbell, David G, Itzen, Aymelt, Trost, Matthias, Muqit, Miratul MK
Published in The EMBO journal (12.11.2015)
Published in The EMBO journal (12.11.2015)
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Complementary regulation of TBC1D1 and AS160 by growth factors, insulin and AMPK activators
Chen, Shuai, Murphy, Jane, Toth, Rachel, Campbell, David G, Morrice, Nick A, Mackintosh, Carol
Published in Biochemical journal (15.01.2008)
Published in Biochemical journal (15.01.2008)
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The DUF1669 domain of FAM83 family proteins anchor casein kinase 1 isoforms
Fulcher, Luke J, Bozatzi, Polyxeni, Tachie-Menson, Theresa, Wu, Kevin Z L, Cummins, Timothy D, Bufton, Joshua C, Pinkas, Daniel M, Dunbar, Karen, Shrestha, Sabin, Wood, Nicola T, Weidlich, Simone, Macartney, Thomas J, Varghese, Joby, Gourlay, Robert, Campbell, David G, Dingwell, Kevin S, Smith, James C, Bullock, Alex N, Sapkota, Gopal P
Published in Science signaling (22.05.2018)
Published in Science signaling (22.05.2018)
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Ulk1-mediated phosphorylation of AMPK constitutes a negative regulatory feedback loop
Löffler, Antje S, Alers, Sebastian, Dieterle, Alexandra M, Keppeler, Hildegard, Franz-Wachtel, Mirita, Kundu, Mondira, Campbell, David G, Wesselborg, Sebastian, Alessi, Dario R, Stork, Björn
Published in Autophagy (01.07.2011)
Published in Autophagy (01.07.2011)
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Journal Article
The LKB1-salt-inducible kinase pathway functions as a key gluconeogenic suppressor in the liver
Patel, Kashyap, Foretz, Marc, Marion, Allison, Campbell, David G., Gourlay, Robert, Boudaba, Nadia, Tournier, Emilie, Titchenell, Paul, Peggie, Mark, Deak, Maria, Wan, Min, Kaestner, Klaus H., Göransson, Olga, Viollet, Benoit, Gray, Nathanael S., Birnbaum, Morris J., Sutherland, Calum, Sakamoto, Kei
Published in Nature communications (04.08.2014)
Published in Nature communications (04.08.2014)
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O-GlcNAcylation of TAB1 modulates TAK1-mediated cytokine release
Pathak, Shalini, Borodkin, Vladimir S, Albarbarawi, Osama, Campbell, David G, Ibrahim, Adel, van Aalten, Daan MF
Published in The EMBO journal (21.03.2012)
Published in The EMBO journal (21.03.2012)
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Journal Article
A PKB-SPEG signaling nexus links insulin resistance with diabetic cardiomyopathy by regulating calcium homeostasis
Quan, Chao, Du, Qian, Li, Min, Wang, Ruizhen, Ouyang, Qian, Su, Shu, Zhu, Sangsang, Chen, Qiaoli, Sheng, Yang, Chen, Liang, Wang, Hong, Campbell, David G., MacKintosh, Carol, Yang, Zhongzhou, Ouyang, Kunfu, Wang, Hong Yu, Chen, Shuai
Published in Nature communications (04.05.2020)
Published in Nature communications (04.05.2020)
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Activation of the thiazide-sensitive Na⁺-Cl⁻ cotransporter by the WNK-regulated kinases SPAK and OSR1
Richardson, Ciaran, Rafiqi, Fatema H, Karlsson, Håkan K.R, Moleleki, Ntsane, Vandewalle, Alain, Campbell, David G, Morrice, Nick A, Alessi, Dario R
Published in Journal of cell science (01.03.2008)
Published in Journal of cell science (01.03.2008)
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Human osteocyte expression of Nerve Growth Factor: The effect of Pentosan Polysulphate Sodium (PPS) and implications for pain associated with knee osteoarthritis
Stapledon, Catherine J M, Tsangari, Helen, Solomon, Lucian B, Campbell, David G, Hurtado, Plinio, Krishnan, Ravi, Atkins, Gerald J
Published in PloS one (26.09.2019)
Published in PloS one (26.09.2019)
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Phosphorylation of synaptic vesicle protein 2A at Thr84 by casein kinase 1 family kinases controls the specific retrieval of synaptotagmin-1
Zhang, Ning, Gordon, Sarah L, Fritsch, Maximilian J, Esoof, Noor, Campbell, David G, Gourlay, Robert, Velupillai, Srikannathasan, Macartney, Thomas, Peggie, Mark, van Aalten, Daan M F, Cousin, Michael A, Alessi, Dario R
Published in The Journal of neuroscience (11.02.2015)
Published in The Journal of neuroscience (11.02.2015)
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Journal Article
New roles for the LKB1-NUAK pathway in controlling myosin phosphatase complexes and cell adhesion
Zagórska, Anna, Deak, Maria, Campbell, David G, Banerjee, Sourav, Hirano, Mariko, Aizawa, Shinichi, Prescott, Alan R, Alessi, Dario R
Published in Science signaling (30.03.2010)
Published in Science signaling (30.03.2010)
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Atg13 and FIP200 act independently of Ulk1 and Ulk2 in autophagy induction
Alers, Sebastian, Löffler, Antje S, Paasch, Florian, Dieterle, Alexandra M, Keppeler, Hildegard, Lauber, Kirsten, Campbell, David G, Fehrenbacher, Birgit, Schaller, Martin, Wesselborg, Sebastian, Stork, Björn
Published in Autophagy (01.12.2011)
Published in Autophagy (01.12.2011)
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