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Published in Proceedings of the National Academy of Sciences - PNAS (29.05.2018)
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Constitutive nuclear accumulation of endogenous alpha-synuclein in mice causes motor impairment and cortical dysfunction, independent of protein aggregation
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Published in Human molecular genetics (18.02.2022)
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The pro-death role of Cited2 in stroke is regulated by E2F1/4 transcription factors
Huang, Tianwen, González, Yasmilde Rodríguez, Qu, Dianbo, Huang, En, Safarpour, Farzaneh, Wang, Eugene, Joselin, Alvin, Im, Doo Soon, Callaghan, Steve M., Boonying, Wassamon, Julian, Lisa, Dunwoodie, Sally L., Slack, Ruth S., Park, David S.
Published in The Journal of biological chemistry (24.05.2019)
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DJ-1 modulates the unfolded protein response and cell death via upregulation of ATF4 following ER stress
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Published in Cell death & disease (12.02.2019)
Published in Cell death & disease (12.02.2019)
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DJ-1 protects the nigrostriatal axis from the neurotoxin MPTP by modulation of the AKT pathway
Aleyasin, Hossein, Rousseaux, Maxime W.C, Marcogliese, Paul C, Hewitt, Sarah J, Irrcher, Isabella, Joselin, Alvin P, Parsanejad, Mohammad, Kim, Raymond H, Rizzu, Patrizia, Callaghan, Steve M, Slack, Ruth S, Mak, Tak W, Park, David S
Published in Proceedings of the National Academy of Sciences - PNAS (16.02.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (16.02.2010)
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Genetic and pharmacological reduction of CDK14 mitigates synucleinopathy
Parmasad, Jean-Louis A., Ricke, Konrad M., Nguyen, Benjamin, Stykel, Morgan G., Buchner-Duby, Brodie, Bruce, Amanda, Geertsma, Haley M., Lian, Eric, Lengacher, Nathalie A., Callaghan, Steve M., Joselin, Alvin, Tomlinson, Julianna J., Schlossmacher, Michael G., Stanford, William L., Ma, Jiyan, Brundin, Patrik, Ryan, Scott D., Rousseaux, Maxime W. C.
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Published in Cell death & disease (04.04.2024)
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Regulation of Ischemic Neuronal Death by E2F4-p130 Protein Complexes
Iyirhiaro, Grace O., Zhang, Yi, Estey, Carmen, O'Hare, Michael J., Safarpour, Farzaneh, Parsanejad, Mohammad, Wang, Suzi, Abdel-Messih, Elizabeth, Callaghan, Steve M., During, Matthew J., Slack, Ruth S., Park, David S.
Published in The Journal of biological chemistry (27.06.2014)
Published in The Journal of biological chemistry (27.06.2014)
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ROS-dependent regulation of Parkin and DJ-1 localization during oxidative stress in neurons
JOSELIN, Alvin P, HEWITT, Sarah J, CALLAGHAN, Steve M, KIM, Raymond H, CHUNG, Young-Hwa, MAK, Tak W, JIE SHEN, SLACK, Ruth S, PARK, David S
Published in Human molecular genetics (15.11.2012)
Published in Human molecular genetics (15.11.2012)
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Essential Role of Cytoplasmic cdk5 and Prx2 in Multiple Ischemic Injury Models, In Vivo
Rashidian, Juliet, Rousseaux, Maxime W, Venderova, Katerina, Qu, Dianbo, Callaghan, Steve M, Phillips, Maryam, Bland, Ross J, During, Matthew J, Mao, Zixu, Slack, Ruth S, Park, David S
Published in The Journal of neuroscience (07.10.2009)
Published in The Journal of neuroscience (07.10.2009)
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A topographical atlas of α-synuclein dosage and cell type-specific expression in adult mouse brain and peripheral organs
Geertsma, Haley M., Fisk, Zoe A., Sauline, Lillian, Prigent, Alice, Kurgat, Kevin, Callaghan, Steve M., Henderson, Michael X., Rousseaux, Maxime W. C.
Published in NPJ Parkinson's Disease (19.03.2024)
Published in NPJ Parkinson's Disease (19.03.2024)
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Inhibition of Calpains Prevents Neuronal and Behavioral Deficits in an MPTP Mouse Model of Parkinson's Disease
Crocker, Stephen J, Smith, Patrice D, Jackson-Lewis, Vernice, Lamba, Wiplore R, Hayley, Shawn P, Grimm, Erich, Callaghan, Steve M, Slack, Ruth S, Melloni, Edon, Przedborski, Serge, Robertson, George S, Anisman, Hymie, Merali, Zul, Park, David S
Published in The Journal of neuroscience (15.05.2003)
Published in The Journal of neuroscience (15.05.2003)
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ROS-dependent regulation of Parkin and DJ-1 localization during oxidative stress in neurons
Joselin, Alvin P, Hewitt, Sarah J, Callaghan, Steve M, Kim, Raymond H, Chung, Young-Hwa, Mak, Tak W, Shen, Jie, Slack, Ruth S, Park, David S
Published in Human molecular genetics (15.11.2012)
Published in Human molecular genetics (15.11.2012)
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Pink1 regulates FKBP5 interaction with AKT/PHLPP and protects neurons from neurotoxin stress induced by MPP
Boonying, Wassamon, Joselin, Alvin, Huang, En, Qu, Dianbo, Safarpour, Farzaneh, Iyirhiaro, Grace O., Gonzalez, Yasmilde Rodriguez, Callaghan, Steve M., Slack, Ruth S., Figeys, Daniel, Chung, Young‐Hwa, Park, David S.
Published in Journal of neurochemistry (01.08.2019)
Published in Journal of neurochemistry (01.08.2019)
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Required Roles of Bax and JNKs in Central and Peripheral Nervous System Death of Retinoblastoma-deficient Mice
Keramaris, Elizabeth, Ruzhynsky, Vladamir A., Callaghan, Steve M., Wong, Estelle, Davis, Roger J., Flavell, Richard, Slack, Ruth S., Park, David S.
Published in The Journal of biological chemistry (04.01.2008)
Published in The Journal of biological chemistry (04.01.2008)
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Characterizing the differential distribution and targets of Sumo1 and Sumo2 in the mouse brain
Suk, Terry R., Nguyen, Trina T., Fisk, Zoe A., Mitkovski, Miso, Geertsma, Haley M., Parmasad, Jean-Louis A., Heer, Meghan M., Callaghan, Steve M., Benseler, Fritz, Brose, Nils, Tirard, Marilyn, Rousseaux, Maxime W.C.
Published in iScience (21.04.2023)
Published in iScience (21.04.2023)
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Pink1 regulates FKBP 5 interaction with AKT / PHLPP and protects neurons from neurotoxin stress induced by MPP
Boonying, Wassamon, Joselin, Alvin, Huang, En, Qu, Dianbo, Safarpour, Farzaneh, Iyirhiaro, Grace O., Gonzalez, Yasmilde Rodriguez, Callaghan, Steve M., Slack, Ruth S., Figeys, Daniel, Chung, Young‐Hwa, Park, David S.
Published in Journal of neurochemistry (01.08.2019)
Published in Journal of neurochemistry (01.08.2019)
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Constitutive nuclear accumulation of endogenous alpha-synuclein in mice causes motor dysfunction and cortical atrophy, independent of protein aggregation
Geertsma, Haley M, Suk, Terry R, Ricke, Konrad M, Horsthuis, Kyra, Parmasad, Jean-Louis A, Fisk, Zoe, Callaghan, Steve M, Maxime Wc Rousseaux
Published in bioRxiv (14.10.2021)
Published in bioRxiv (14.10.2021)
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