Tau accumulation in astrocytes of the dentate gyrus induces neuronal dysfunction and memory deficits in Alzheimer’s disease
Richetin, Kevin, Steullet, Pascal, Pachoud, Mathieu, Perbet, Romain, Parietti, Enea, Maheswaran, Mathischan, Eddarkaoui, Sabiha, Bégard, Séverine, Pythoud, Catherine, Rey, Maria, Caillierez, Raphaëlle, Q Do, Kim, Halliez, Sophie, Bezzi, Paola, Buée, Luc, Leuba, Geneviève, Colin, Morvane, Toni, Nicolas, Déglon, Nicole
Published in Nature neuroscience (01.12.2020)
Published in Nature neuroscience (01.12.2020)
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Beneficial Effect of a Selective Adenosine A2A Receptor Antagonist in the APPswe/PS1dE9 Mouse Model of Alzheimer’s Disease
Faivre, Emilie, Coelho, Joana E., Zornbach, Katja, Malik, Enas, Baqi, Younis, Schneider, Marion, Cellai, Lucrezia, Carvalho, Kevin, Sebda, Shéhérazade, Figeac, Martin, Eddarkaoui, Sabiha, Caillierez, Raphaëlle, Chern, Yijuang, Heneka, Michael, Sergeant, Nicolas, Müller, Christa E., Halle, Annett, Buée, Luc, Lopes, Luisa V., Blum, David
Published in Frontiers in molecular neuroscience (12.07.2018)
Published in Frontiers in molecular neuroscience (12.07.2018)
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Beneficial effects of exercise in a transgenic mouse model of Alzheimer's disease-like Tau pathology
Belarbi, Karim, Burnouf, Sylvie, Fernandez-Gomez, Francisco-Jose, Laurent, Cyril, Lestavel, Sophie, Figeac, Martin, Sultan, Audrey, Troquier, Laetitia, Leboucher, Antoine, Caillierez, Raphaëlle, Grosjean, Marie-Eve, Demeyer, Dominique, Obriot, Hélène, Brion, Ingrid, Barbot, Bérangère, Galas, Marie-Christine, Staels, Bart, Humez, Sandrine, Sergeant, Nicolas, Schraen-Maschke, Susanna, Muhr-Tailleux, Anne, Hamdane, Malika, Buée, Luc, Blum, David
Published in Neurobiology of disease (01.08.2011)
Published in Neurobiology of disease (01.08.2011)
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Journal Article
Encephalopathy induced by Alzheimer brain inoculation in a non-human primate
Gary, Charlotte, Lam, Suzanne, Hérard, Anne-Sophie, Koch, James E, Petit, Fanny, Gipchtein, Pauline, Sawiak, Stephen J, Caillierez, Raphaëlle, Eddarkaoui, Sabiha, Colin, Morvane, Aujard, Fabienne, Deslys, Jean-Philippe, Brouillet, Emmanuel, Buée, Luc, Comoy, Emmanuel E, Pifferi, Fabien, Picq, Jean-Luc, Dhenain, Marc
Published in Acta neuropathologica communications (04.09.2019)
Published in Acta neuropathologica communications (04.09.2019)
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Ectosomes: a new mechanism for non-exosomal secretion of tau protein
Dujardin, Simon, Bégard, Séverine, Caillierez, Raphaëlle, Lachaud, Cédrick, Delattre, Lucie, Carrier, Sébastien, Loyens, Anne, Galas, Marie-Christine, Bousset, Luc, Melki, Ronald, Aurégan, Gwennaëlle, Hantraye, Philippe, Brouillet, Emmanuel, Buée, Luc, Colin, Morvane
Published in PloS one (27.06.2014)
Published in PloS one (27.06.2014)
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Journal Article
Hippocampal T cell infiltration promotes neuroinflammation and cognitive decline in a mouse model of tauopathy
Laurent, Cyril, Dorothée, Guillaume, Hunot, Stéphane, Martin, Elodie, Monnet, Yann, Duchamp, Marie, Dong, Yuan, Légeron, François-Pierre, Leboucher, Antoine, Burnouf, Sylvie, Faivre, Emilie, Carvalho, Kévin, Caillierez, Raphaëlle, Zommer, Nadège, Demeyer, Dominique, Jouy, Nathalie, Sazdovitch, Veronique, Schraen-Maschke, Susanna, Delarasse, Cécile, Buée, Luc, Blum, David
Published in Brain (London, England : 1878) (01.01.2017)
Published in Brain (London, England : 1878) (01.01.2017)
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Prevention of tau seeding and propagation by immunotherapy with a central tau epitope antibody
Albert, Marie, Mairet-Coello, Georges, Danis, Clément, Lieger, Sarah, Caillierez, Raphaëlle, Carrier, Sébastien, Skrobala, Emilie, Landrieu, Isabelle, Michel, Anne, Schmitt, Mathieu, Citron, Martin, Downey, Patrick, Courade, Jean-Philippe, Buée, Luc, Colin, Morvane
Published in Brain (London, England : 1878) (01.06.2019)
Published in Brain (London, England : 1878) (01.06.2019)
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The Chemokine MIP-1α/CCL3 impairs mouse hippocampal synaptic transmission, plasticity and memory
Marciniak, Elodie, Faivre, Emilie, Dutar, Patrick, Alves Pires, Claire, Demeyer, Dominique, Caillierez, Raphaëlle, Laloux, Charlotte, Buée, Luc, Blum, David, Humez, Sandrine
Published in Scientific reports (29.10.2015)
Published in Scientific reports (29.10.2015)
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Tau Phosphorylation and Sevoflurane Anesthesia
Le Freche, Hélène, Brouillette, Jonathan, Fernandez-Gomez, Francisco-José, Patin, Pauline, Caillierez, Raphaëlle, Zommer, Nadège, Sergeant, Nicolas, Buée-Scherrer, Valérie, Lebuffe, Gilles, Blum, David, Buée, Luc
Published in Anesthesiology (Philadelphia) (01.04.2012)
Published in Anesthesiology (Philadelphia) (01.04.2012)
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Inhibition of Tau seeding by targeting Tau nucleation core within neurons with a single domain antibody fragment
Danis, Clément, Dupré, Elian, Zejneli, Orgeta, Caillierez, Raphaëlle, Arrial, Alexis, Bégard, Séverine, Mortelecque, Justine, Eddarkaoui, Sabiha, Loyens, Anne, Cantrelle, François-Xavier, Hanoulle, Xavier, Rain, Jean-Christophe, Colin, Morvane, Buée, Luc, Landrieu, Isabelle
Published in Molecular therapy (06.04.2022)
Published in Molecular therapy (06.04.2022)
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Impact of chronic doxycycline treatment in the APP/PS1 mouse model of Alzheimer's disease
Gomez-Murcia, Victoria, Carvalho, Kevin, Thiroux, Bryan, Caillierez, Raphaëlle, Besegher, Melanie, Sergeant, Nicolas, Buée, Luc, Faivre, Emile, Blum, David
Published in Neuropharmacology (15.05.2022)
Published in Neuropharmacology (15.05.2022)
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New piperazine multi-effect drugs prevent neurofibrillary degeneration and amyloid deposition, and preserve memory in animal models of Alzheimer's disease
Sergeant, Nicolas, Vingtdeux, Valérie, Eddarkaoui, Sabiha, Gay, Marion, Evrard, Caroline, Le Fur, Nicolas, Laurent, Cyril, Caillierez, Raphaelle, Obriot, Hélène, Larchanché, Paul-Emmanuel, Farce, Amaury, Coevoet, Mathilde, Carato, Pascal, Kouach, Mostafa, Descat, Amandine, Dallemagne, Patrick, Buée-Scherrer, Valérie, Blum, David, Hamdane, Malika, Buée, Luc, Melnyk, Patricia
Published in Neurobiology of disease (01.09.2019)
Published in Neurobiology of disease (01.09.2019)
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Neuron-to-neuron wild-type Tau protein transfer through a trans-synaptic mechanism: relevance to sporadic tauopathies
Dujardin, Simon, Lécolle, Katia, Caillierez, Raphaëlle, Bégard, Séverine, Zommer, Nadège, Lachaud, Cédrick, Carrier, Sébastien, Dufour, Noëlle, Aurégan, Gwennaëlle, Winderickx, Joris, Hantraye, Philippe, Déglon, Nicole, Colin, Morvane, Buée, Luc
Published in Acta neuropathologica communications (30.01.2014)
Published in Acta neuropathologica communications (30.01.2014)
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Journal Article
Different tau species lead to heterogeneous tau pathology propagation and misfolding
Dujardin, Simon, Bégard, Séverine, Caillierez, Raphaëlle, Lachaud, Cédrick, Carrier, Sébastien, Lieger, Sarah, Gonzalez, Jose A, Deramecourt, Vincent, Déglon, Nicole, Maurage, Claude-Alain, Frosch, Matthew P, Hyman, Bradley T, Colin, Morvane, Buée, Luc
Published in Acta neuropathologica communications (29.11.2018)
Published in Acta neuropathologica communications (29.11.2018)
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Extracellular vesicles: Major actors of heterogeneity in tau spreading among human tauopathies
Leroux, Elodie, Perbet, Romain, Caillierez, Raphaëlle, Richetin, Kevin, Lieger, Sarah, Espourteille, Jeanne, Bouillet, Thomas, Bégard, Séverine, Danis, Clément, Loyens, Anne, Toni, Nicolas, Déglon, Nicole, Deramecourt, Vincent, Schraen-Maschke, Susanna, Buée, Luc, Colin, Morvane
Published in Molecular therapy (02.02.2022)
Published in Molecular therapy (02.02.2022)
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Cholesterol 24-hydroxylase defect is implicated in memory impairments associated with Alzheimer-like Tau pathology
Burlot, Marie-Anne, Braudeau, Jérôme, Michaelsen-Preusse, Kristin, Potier, Brigitte, Ayciriex, Sophie, Varin, Jennifer, Gautier, Benoit, Djelti, Fathia, Audrain, Mickael, Dauphinot, Luce, Fernandez-Gomez, Francisco-Jose, Caillierez, Raphaëlle, Laprévote, Olivier, Bièche, Ivan, Auzeil, Nicolas, Potier, Marie-Claude, Dutar, Patrick, Korte, Martin, Buée, Luc, Blum, David, Cartier, Nathalie
Published in Human molecular genetics (01.11.2015)
Published in Human molecular genetics (01.11.2015)
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Journal Article
Tau Phosphorylation and Sevoflurane Anesthesia: An Association to Postoperative Cognitive Impairment
FRECHE, Hélène Le, BROUILLETTE, Jonathan, BUEE, Luc, FERNANDEZ-GOMEZ, Francisco-Jose, PATIN, Pauline, CAILLIEREZ, Raphaëlle, ZOMMER, Nadège, SERGEANT, Nicolas, BUEE-SCHERRER, Valérie, LEBUFFE, Gilles, BLUM, David
Published in Anesthesiology (Philadelphia) (01.04.2012)
Published in Anesthesiology (Philadelphia) (01.04.2012)
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Journal Article
Chronic Sodium Selenate Treatment Restores Deficits in Cognition and Synaptic Plasticity in a Murine Model of Tauopathy
Ahmed, Tariq, Van der Jeugd, Ann, Caillierez, Raphaëlle, Buée, Luc, Blum, David, D’Hooge, Rudi, Balschun, Detlef
Published in Frontiers in molecular neuroscience (08.10.2020)
Published in Frontiers in molecular neuroscience (08.10.2020)
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Neuronal A2A receptor exacerbates synapse loss and memory deficits in APP/PS1 mice
Gomez-Murcia, Victoria, Launay, Agathe, Carvalho, Kévin, Burgard, Anaëlle, Meriaux, Céline, Caillierez, Raphaëlle, Eddarkaoui, Sabiha, Kilinc, Devrim, Siedlecki-Wullich, Dolores, Besegher, Mélanie, Bégard, Séverine, Thiroux, Bryan, Jung, Matthieu, Nebie, Ouada, Wisztorski, Maxence, Déglon, Nicole, Montmasson, Claire, Bemelmans, Alexis-Pierre, Hamdane, Malika, Lebouvier, Thibaud, Vieau, Didier, Fournier, Isabelle, Buee, Luc, Lévi, Sabine, Lopes, Luisa V, Boutillier, Anne-Laurence, Faivre, Emilie, Blum, David
Published in Brain (London, England : 1878) (01.08.2024)
Published in Brain (London, England : 1878) (01.08.2024)
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Detrimental effects of diet-induced obesity on τ pathology are independent of insulin resistance in τ transgenic mice
Leboucher, Antoine, Laurent, Cyril, Fernandez-Gomez, Francisco-José, Burnouf, Sylvie, Troquier, Laetitia, Eddarkaoui, Sabiha, Demeyer, Dominique, Caillierez, Raphaëlle, Zommer, Nadège, Vallez, Emmanuelle, Bantubungi, Kadiombo, Breton, Christophe, Pigny, Pascal, Buée-Scherrer, Valérie, Staels, Bart, Hamdane, Malika, Tailleux, Anne, Buée, Luc, Blum, David
Published in Diabetes (New York, N.Y.) (01.05.2013)
Published in Diabetes (New York, N.Y.) (01.05.2013)
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