Preclinical characterization of the CDK4/6 inhibitor LY2835219: in-vivo cell cycle-dependent/independent anti-tumor activities alone/in combination with gemcitabine
Gelbert, Lawrence M., Cai, Shufen, Lin, Xi, Sanchez-Martinez, Concepcion, del Prado, Miriam, Lallena, Maria Jose, Torres, Raquel, Ajamie, Rose T., Wishart, Graham N., Flack, Robert Steven, Neubauer, Blake Lee, Young, Jamie, Chan, Edward M., Iversen, Philip, Cronier, Damien, Kreklau, Emiko, de Dios, Alfonso
Published in Investigational new drugs (01.10.2014)
Published in Investigational new drugs (01.10.2014)
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Journal Article
Semi-Mechanistic Pharmacokinetic/Pharmacodynamic Modeling of the Antitumor Activity of LY2835219, a New Cyclin-Dependent Kinase 4/6 Inhibitor, in Mice Bearing Human Tumor Xenografts
TATE, Sonya C, SHUFEN CAI, AJAMIE, Rose T, BURKE, Teresa, BECKMANN, Richard P, CHAN, Edward M, DE DIOS, Alfonso, WISHART, Graham N, GELBERT, Lawrence M, CRONIER, Damien M
Published in Clinical cancer research (15.07.2014)
Published in Clinical cancer research (15.07.2014)
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Journal Article
ERK Inhibitor LY3214996 Targets ERK Pathway-Driven Cancers: A Therapeutic Approach Toward Precision Medicine
Bhagwat, Shripad V, McMillen, William T, Cai, Shufen, Zhao, Baohui, Whitesell, Matthew, Shen, Weihua, Kindler, Lisa, Flack, Robert S, Wu, Wenjuan, Anderson, Bryan, Zhai, Yan, Yuan, Xiu-Juan, Pogue, Meghann, Van Horn, Robert D, Rao, Xi, McCann, Denis, Dropsey, Andrew J, Manro, Jason, Walgren, Jennie, Yuen, Eunice, Rodriguez, Michael J, Plowman, Gregory D, Tiu, Ramon V, Joseph, Sajan, Peng, Sheng-Bin
Published in Molecular cancer therapeutics (01.02.2020)
Published in Molecular cancer therapeutics (01.02.2020)
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Journal Article
Abstract 5225: Temporal inhibition of ERK is sufficient for tumor growth inhibition in KRAS -mutant or BRAF -mutant tumors
Bhagwat, Shripad V., Shen, Weihua, Zhao, Baohui, Cai, Shufen, Kindler, Lisa, McMillen, William T., Yuen, Eunice, McCann, Denis, Manro, Jason, Dropsey, Andrew J., Willard, Melinda D., Joseph, Sajan, Peng, Sheng-Bin
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Journal Article
Abstract 3231: Identifying high quality, potent and selective pyrimidinylthienopyrrolone inhibitors of ERK1/2 kinase: LY3214996
Zhao, Gaiying, McMillen, William T., Cai, Shufen, Zhao, Baohui, Whitesell, Matthew, Wu, Wenjuan, Huss, Karen, Anderson, Bryan, Yuan, Xiu-Juan, Jaken, Susan, Kindler, Lisa, Flack, Robert S., McCann, Denis, Mathes, Brian, Dropsey, Andrew J., Walgren, Jennie, Yuen, Eunice, Manro, Jason, Gong, Xueqian, Cortez, Guillermo, McLean, Johnathan, Rodriguez, Michael J., Tiu, Ramon V., Bhagwat, Shripad V., Joseph, Sajan
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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Journal Article
Abstract 4973: Discovery of LY3214996, a selective and novel ERK1/2 inhibitor with potent antitumor activities in cancer models with MAPK pathway alterations
Bhagwat, Shripad V., McMillen, William T., Cai, Shufen, Zhao, Baohui, Whitesell, Matthew, Kindler, Lisa, Flack, Robert S., Wu, Wenjuan, Huss, Karen, Anderson, Bryan, Yuan, Xiu-Juan, Jaken, Susan, McCann, Denis, Mathes, Brian, Dropsey, Andrew J., Manro, Jason, Walgren, Jennie, Yuen, Eunice, Gong, Xueqian, Rodriguez, Michael J., Huang, Jianping, Tiu, Ramon V., Joseph, Sajan, Peng, Sheng-Bin
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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Journal Article
Abstract B233: Identification and characterization of LY2835219: A potent oral inhibitor of the cyclin-dependent kinases 4 and 6 (CDK4/6) with broad in vivo antitumor activity
Gelbert, Lawrence M., Cai, Shufen, Lin, Xi, Sanchez-Martinez, Concepcion, del Prado, Miriam, Lallena, Maria Jose, Torres, Raquel, Ajamie, Rose T., Kreklau, Emiko, Wishart, Graham N., Flack, Robert Steven, Neubauer, Blake, Young, Jamie, Chan, Edward M., Iversen, Phillip, Cronier, Damien, De Dios, Alfonso
Published in Molecular cancer therapeutics (12.11.2011)
Published in Molecular cancer therapeutics (12.11.2011)
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Journal Article
Package for dispensing biphasic cosmetic composition
WU ZHENGPING, LI CHANGSHOU, ZHENG JINGWEN, CAI SHUFEN, ZHANG JUNJI, HE RONG, LI QIAO
Year of Publication 14.06.2024
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Year of Publication 14.06.2024
Patent
Electronic device
CHEN ZHIQUN, WANG YILIANG, CHEN JIAHONG, CAI SHUFEN, ZHANG JIAQI, WU QIMING
Year of Publication 23.11.2021
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Year of Publication 23.11.2021
Patent