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Extreme Vulnerability of IDH1 Mutant Cancers to NAD+ Depletion
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A Hyperactive RelA/p65-Hexokinase 2 Signaling Axis Drives Primary Central Nervous System Lymphoma
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Published in Cancer research (Chicago, Ill.) (01.12.2020)
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Poly(ADP-ribose) Glycohydrolase Inhibition Sequesters NAD + to Potentiate the Metabolic Lethality of Alkylating Chemotherapy in IDH-Mutant Tumor Cells
Nagashima, Hiroaki, Lee, Christine K, Tateishi, Kensuke, Higuchi, Fumi, Subramanian, Megha, Rafferty, Seamus, Melamed, Lisa, Miller, Julie J, Wakimoto, Hiroaki, Cahill, Daniel P
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Published in Cancer discovery (01.11.2020)
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