Chondroitinase improves anatomical and functional outcomes after primate spinal cord injury
Rosenzweig, Ephron S., Salegio, Ernesto A., Liang, Justine J., Weber, Janet L., Weinholtz, Chase A., Brock, John H., Moseanko, Rod, Hawbecker, Stephanie, Pender, Roger, Cruzen, Christina L., Iaci, Jennifer F., Caggiano, Anthony O., Blight, Andrew R., Haenzi, Barbara, Huie, J. Russell, Havton, Leif A., Nout-Lomas, Yvette S., Fawcett, James W., Ferguson, Adam R., Beattie, Michael S., Bresnahan, Jacqueline C., Tuszynski, Mark H.
Published in Nature neuroscience (01.08.2019)
Published in Nature neuroscience (01.08.2019)
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Sigma-2 Receptors-From Basic Biology to Therapeutic Target: A Focus on Age-Related Degenerative Diseases
Lizama, Britney N, Kahle, Jennifer, Catalano, Susan M, Caggiano, Anthony O, Grundman, Michael, Hamby, Mary E
Published in International journal of molecular sciences (26.03.2023)
Published in International journal of molecular sciences (26.03.2023)
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Journal Article
rHIgM22 enhances remyelination in the brain of the cuprizone mouse model of demyelination
Mullin, Ariana P, Cui, Charlene, Wang, Yu, Wang, Jing, Troy, Erika, Caggiano, Anthony O, Parry, Tom J, Colburn, Raymond W, Pavlopoulos, Elias
Published in Neurobiology of disease (01.09.2017)
Published in Neurobiology of disease (01.09.2017)
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A pilot study to evaluate the effect of CT1812 treatment on synaptic density and other biomarkers in Alzheimer's disease
van Dyck, Christopher H, Mecca, Adam P, O'Dell, Ryan S, Bartlett, Hugh H, Diepenbrock, Nina G, Huang, Yiyun, Hamby, Mary E, Grundman, Michael, Catalano, Susan M, Caggiano, Anthony O, Carson, Richard E
Published in Alzheimer's research & therapy (25.01.2024)
Published in Alzheimer's research & therapy (25.01.2024)
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The Evaluation of Magnesium Chloride within a Polyethylene Glycol Formulation in a Porcine Model of Acute Spinal Cord Injury
Streijger, Femke, Lee, Jae H T, Manouchehri, Neda, Okon, Elena B, Tigchelaar, Seth, Anderson, Lisa M, Dekaban, Greg A, Rudko, David A, Menon, Ravi S, Iaci, Jennifer F, Button, Donald C, Vecchione, Andrea M, Konovalov, Andrey, Sarmiere, Patrick D, Ung, Chi, Caggiano, Anthony O, Kwon, Brian K
Published in Journal of neurotrauma (15.12.2016)
Published in Journal of neurotrauma (15.12.2016)
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Journal Article
Intravenous glial growth factor 2 (GGF2) isoform of neuregulin-1β improves left ventricular function, gene and protein expression in rats after myocardial infarction
Hill, Michael F, Patel, Amish V, Murphy, Abigail, Smith, Holly M, Galindo, Cristi L, Pentassuglia, Laura, Peng, Xuyang, Lenneman, Carrie G, Odiete, Oghenerukevwe, Friedman, David B, Kronenberg, Marvin W, Zheng, Siyuen, Zhao, Zhongming, Song, Yanna, Harrell, Jr, Frank E, Srinivas, Maya, Ganguly, Anindita, Iaci, Jennifer, Parry, Tom J, Caggiano, Anthony O, Sawyer, Douglas B
Published in PloS one (21.02.2013)
Published in PloS one (21.02.2013)
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Journal Article
A Phase I, Single Ascending Dose Study of Cimaglermin Alfa (Neuregulin 1β3) in Patients With Systolic Dysfunction and Heart Failure
Lenihan, Daniel J., MD, Anderson, Sarah A., ACNP, Lenneman, Carrie Geisberg, MD, Brittain, Evan, MD, MSCI, Muldowney, James A.S., MD, Mendes, Lisa, MD, Zhao, Ping Z., PhD, Iaci, Jennifer, MS, Frohwein, Stephen, MD, Zolty, Ronald, MD, PhD, Eisen, Andrew, MD, PhD, Sawyer, Douglas B., MD, PhD, Caggiano, Anthony O., MD, PhD
Published in JACC. Basic to translational science (01.12.2016)
Published in JACC. Basic to translational science (01.12.2016)
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Journal Article
Neuregulin-1 attenuated doxorubicin-induced decrease in cardiac troponins
Bian, Yun, Sun, Maoyun, Silver, Marcy, Ho, Kalon K. L, Marchionni, Mark A, Caggiano, Anthony O, Stone, James R, Amende, Ivo, Hampton, Thomas G, Morgan, James P, Yan, Xinhua
Published in American journal of physiology. Heart and circulatory physiology (01.12.2009)
Published in American journal of physiology. Heart and circulatory physiology (01.12.2009)
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Journal Article
Human IgM antibody rHIgM22 promotes phagocytic clearance of myelin debris by microglia
Zorina, Yana, Stricker, Jason, Caggiano, Anthony O., Button, Donald C.
Published in Scientific reports (20.06.2018)
Published in Scientific reports (20.06.2018)
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Journal Article
The antibody rHIgM22 facilitates hippocampal remyelination and ameliorates memory deficits in the cuprizone mouse model of demyelination
Cui, Charlene, Wang, Jing, Mullin, Ariana P., Caggiano, Anthony O., Parry, Tom J., Colburn, Raymond W., Pavlopoulos, Elias
Published in Brain research (01.09.2018)
Published in Brain research (01.09.2018)
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Journal Article
Transmembrane protein 97 is a potential synaptic amyloid beta receptor in human Alzheimer’s disease
Colom-Cadena, Martí, Toombs, Jamie, Simzer, Elizabeth, Holt, Kristjan, McGeachan, Robert, Tulloch, Jane, Jackson, Rosemary J., Catterson, James H., Spires-Jones, Maxwell P., Rose, Jamie, Waybright, Lora, Caggiano, Anthony O., King, Declan, Gobbo, Francesco, Davies, Caitlin, Hooley, Monique, Dunnett, Sophie, Tempelaar, Robert, Meftah, Soraya, Tzioras, Makis, Hamby, Mary E., Izzo, Nicholas J., Catalano, Susan M., Durrant, Claire S., Smith, Colin, Dando, Owen, Spires-Jones, Tara L.
Published in Acta neuropathologica (01.06.2024)
Published in Acta neuropathologica (01.06.2024)
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CT1812 biomarker signature from a meta‐analysis of CSF proteomic findings from two Phase 2 clinical trials in Alzheimer's disease
Lizama, Britney N., Williams, Claire, North, Hilary A., Pandey, Kiran, Duong, Duc, Di Caro, Valentina, Mecca, Adam P., Blennow, Kaj, Zetterberg, Henrik, Levey, Allan I., Grundman, Michael, Dyck, Christopher H., Caggiano, Anthony O., Seyfried, Nicholas T., Hamby, Mary E.
Published in Alzheimer's & dementia (21.08.2024)
Published in Alzheimer's & dementia (21.08.2024)
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Recovery of sensorimotor function following sciatic nerve injury across multiple rat strains
Ganguly, Anindita, McEwen, Corissa, Troy, Erika L., Colburn, Raymond W., Caggiano, Anthony O., Schallert, Timothy J., Parry, Tom J.
Published in Journal of neuroscience methods (01.01.2017)
Published in Journal of neuroscience methods (01.01.2017)
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Journal Article
Transient Changes in Hepatic Physiology That Alter Bilirubin and Bile Acid Transport May Explain Elevations in Liver Chemistries Observed in Clinical Trials of GGF2 (Cimaglermin Alfa)
Mosedale, Merrie, Button, Donald, Jackson, Jonathan P, Freeman, Kimberly M, Brouwer, Kenneth R, Caggiano, Anthony O, Eisen, Andrew, Iaci, Jennifer F, Parry, Tom J, Stanulis, Ric, Srinivas, Maya, Watkins, Paul B
Published in Toxicological sciences (01.02.2018)
Published in Toxicological sciences (01.02.2018)
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Journal Article
Improving murine embryonic stem cell differentiation into cardiomyocytes with neuregulin-1: differential expression of microRNA
Sun, Maoyun, Yan, Xinhua, Bian, Yun, Caggiano, Anthony O, Morgan, James P
Published in American Journal of Physiology: Cell Physiology (01.07.2011)
Published in American Journal of Physiology: Cell Physiology (01.07.2011)
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Journal Article
Species-specific effects of neuregulin-1β (cimaglermin alfa) on glucose handling in animal models and humans with heart failure
Huang, Zhihong, Sawyer, Douglas B., Troy, Erika L., McEwen, Corissa, Cleator, John H., Murphy, Abigail, Caggiano, Anthony O., Eisen, Andrew, Parry, Tom J.
Published in Toxicology and applied pharmacology (01.10.2017)
Published in Toxicology and applied pharmacology (01.10.2017)
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Journal Article
Anti‐Remodeling and Anti‐Fibrotic Effects of the Neuregulin‐1β Glial Growth Factor 2 in a Large Animal Model of Heart Failure
Galindo, Cristi L., Kasasbeh, Ehab, Murphy, Abigail, Ryzhov, Sergey, Lenihan, Sean, Ahmad, Farhaan A., Williams, Philip, Nunnally, Amy, Adcock, Jamie, Song, Yanna, Harrell, Frank E., Tran, Truc‐Linh, Parry, Tom J., Iaci, Jen, Ganguly, Anindita, Feoktistov, Igor, Stephenson, Matthew K., Caggiano, Anthony O., Sawyer, Douglas B., Cleator, John H.
Published in Journal of the American Heart Association (23.10.2014)
Published in Journal of the American Heart Association (23.10.2014)
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Journal Article
Effects of neuregulin GGF2 (cimaglermin alfa) dose and treatment frequency on left ventricular function in rats following myocardial infarction
Parry, Tom J., Ganguly, Anindita, Troy, Erika L., Luis Guerrero, J., Iaci, Jennifer F., Srinivas, Maya, Vecchione, Andrea M., Button, Donald C., Hackett, Craig S., Zolty, Ronald, Sawyer, Douglas B., Caggiano, Anthony O.
Published in European journal of pharmacology (05.02.2017)
Published in European journal of pharmacology (05.02.2017)
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