Current directions in tau research: Highlights from Tau 2020
Sexton, Claire, Snyder, Heather, Beher, Dirk, Boxer, Adam L., Brannelly, Pat, Brion, Jean‐Pierre, Buée, Luc, Cacace, Angela M., Chételat, Gaël, Citron, Martin, DeVos, Sarah L., Diaz, Kristophe, Feldman, Howard H., Frost, Bess, Goate, Alison M., Gold, Michael, Hyman, Bradley, Johnson, Keith, Karch, Celeste M., Kerwin, Diana R., Koroshetz, Walter J., Litvan, Irene, Morris, Huw R., Mummery, Catherine J., Mutamba, James, Patterson, Marc C., Quiroz, Yakeel T., Rabinovici, Gil D., Rommel, Amy, Shulman, Melanie B., Toledo‐Sherman, Leticia M., Weninger, Stacie, Wildsmith, Kristin R., Worley, Susan L., Carrillo, Maria C.
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Published in Alzheimer's & dementia (01.05.2022)
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Tau overexpression impacts a neuroinflammation gene expression network perturbed in Alzheimer's disease
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Published in PloS one (25.08.2014)
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Identification and characterization of a MAPT-targeting locked nucleic acid antisense oligonucleotide therapeutic for tauopathies
Easton, Amy, Jensen, Marianne L., Wang, Congwei, Hagedorn, Peter H., Li, Yuwen, Weed, Michael, Meredith, Jere E., Guss, Valerie, Jones, Kelli, Gill, Martin, Krause, Carol, Brown, Jeffrey M., Hunihan, Lisa, Natale, Joanne, Fernandes, Alda, Lu, Yifeng, Polino, Joe, Bookbinder, Mark, Cadelina, Greg, Benitex, Yulia, Sane, Ramola, Morrison, John, Drexler, Dieter, Mercer, Stephen E., Bon, Charlotte, Pandya, Nikhil J., Jagasia, Ravi, Ou Yang, Tai-Hsien, Distler, Tania, Grüninger, Fiona, Meldgaard, Michael, Terrigno, Marco, Macor, John E., Albright, Charles F., Loy, James, Hoeg, Anja M., Olson, Richard E., Cacace, Angela M.
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Published in Molecular therapy. Nucleic acids (13.09.2022)
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New therapies on the horizon: Targeted protein degradation in neuroscience
Gregory, James A., Hickey, Christopher M., Chavez, Juan, Cacace, Angela M.
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Published in Cell chemical biology (19.09.2024)
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p38 α Regulates Expression of DUX4 in a Model of Facioscapulohumeral Muscular Dystrophy
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Co-opting the E3 ligase KLHDC2 for targeted protein degradation by small molecules
Hickey, Christopher M., Digianantonio, Katherine M., Zimmermann, Kurt, Harbin, Alicia, Quinn, Connor, Patel, Avani, Gareiss, Peter, Chapman, Amanda, Tiberi, Bernadette, Dobrodziej, Jennifer, Corradi, John, Cacace, Angela M., Langley, David R., Békés, Miklós
Published in Nature structural & molecular biology (01.02.2024)
Published in Nature structural & molecular biology (01.02.2024)
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Acute Neurotoxicity of Antisense Oligonucleotides After Intracerebroventricular Injection Into Mouse Brain Can Be Predicted from Sequence Features
Hagedorn, Peter H, Brown, Jeffrey M, Easton, Amy, Pierdomenico, Maria, Jones, Kelli, Olson, Richard E, Mercer, Stephen E, Li, Dong, Loy, James, Høg, Anja M, Jensen, Marianne L, Gill, Martin, Cacace, Angela M
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Published in Nucleic acid therapeutics (01.06.2022)
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Neuronal calcineurin transcriptional targets parallel changes observed in Alzheimer disease brain
Hopp, Sarah C., Bihlmeyer, Nathan A., Corradi, John P., Vanderburg, Charles, Cacace, Angela M., Das, Sudeshna, Clark, Timothy W., Betensky, Rebecca A., Hyman, Bradley T., Hudry, Eloise
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Published in Journal of neurochemistry (01.10.2018)
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Discovery of D1 Dopamine Receptor Positive Allosteric Modulators: Characterization of Pharmacology and Identification of Residues that Regulate Species Selectivity
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The structure of human tau-tubulin kinase 1 both in the apo form and in complex with an inhibitor
Kiefer, Susan E., Chang, ChiehYing J., Kimura, S. Roy, Gao, Mian, Xie, Dianlin, Zhang, Yaqun, Zhang, Guifen, Gill, Martin B., Mastalerz, Harold, Thompson, Lorin A., Cacace, Angela M., Sheriff, Steven
Published in Acta crystallographica. Section F, Structural biology communications (01.02.2014)
Published in Acta crystallographica. Section F, Structural biology communications (01.02.2014)
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Identification of Constitutive and Ras-Inducible Phosphorylation Sites of KSR: Implications for 14-3-3 Binding, Mitogen-Activated Protein Kinase Binding, and KSR Overexpression
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Published in Molecular and Cellular Biology (01.01.1999)
Published in Molecular and Cellular Biology (01.01.1999)
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Human neural progenitor cells as an in vitro model system to study mitochondrial dysfunction in Alzheimer's disease
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Published in Alzheimer's & dementia (01.07.2010)
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JENSEN MARIANNE LERBECH, CACACE ANGELA M, MCDONALD IVAR M, HAGEDORN PETER, DEVIDZE NINO, LOY JAMES K, BALDICK CARL J, PENDRI ANNAPURNA, OLSON RICHARD E, MEREDITH JERE E. JR
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Year of Publication 16.12.2020
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알파-시누클레인을 표적화하는 안티센스 올리고뉴클레오티드 및 그의 용도
JENSEN MARIANNE LERBECH, CACACE ANGELA M, MCDONALD IVAR M, HAGEDORN PETER, MEREDITH JR. JERE E, DEVIDZE NINO, LOY JAMES K, BALDICK CARL J, PENDRI ANNAPURNA, OLSON RICHARD E
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Year of Publication 15.12.2020
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타우 안티센스 올리고머와 그 용도
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Year of Publication 20.02.2018
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Year of Publication 20.02.2018
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Distinctive transcriptome alterations of prefrontal pyramidal neurons in schizophrenia and schizoaffective disorder
Arion, D, Corradi, J P, Tang, S, Datta, D, Boothe, F, He, A, Cacace, A M, Zaczek, R, Albright, C F, Tseng, G, Lewis, D A
Published in Molecular psychiatry (01.11.2015)
Published in Molecular psychiatry (01.11.2015)
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O5‐04‐05: A NEW THERAPEUTIC STRATEGY FOR TAUOPATHIES: DISCOVERY OF HIGHLY POTENT BRAIN PENETRANT PROTACTM DEGRADER MOLECULES THAT TARGET PATHOLOGIC TAU PROTEIN SPECIES
Cacace, Angela M., Chandler, J., Flanagan, J.J., Berlin, M., Cadelina, G., Pizzano, J., Bookbinder, M., Crews, C.M., Crew, A.P., Taylor, I., Houston, J.
Published in Alzheimer's & dementia (01.07.2019)
Published in Alzheimer's & dementia (01.07.2019)
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