Mechanism of inhibition of human glucose transporter GLUT1 is conserved between cytochalasin B and phenylalanine amides
Kapoor, Khyati, Finer-Moore, Janet S., Pedersen, Bjørn P., Caboni, Laura, Waight, Andrew, Hillig, Roman C., Bringmann, Peter, Heisler, Iring, Müller, Thomas, Siebeneicher, Holger, Stroud, Robert M.
Published in Proceedings of the National Academy of Sciences - PNAS (26.04.2016)
Published in Proceedings of the National Academy of Sciences - PNAS (26.04.2016)
Get full text
Journal Article
Structure-based discovery of NANOG variant with enhanced properties to promote self-renewal and reprogramming of pluripotent stem cells
Hayashi, Yohei, Caboni, Laura, Das, Debanu, Yumoto, Fumiaki, Clayton, Thomas, Deller, Marc C., Nguyen, Phuong, Farr, Carol L., Chiu, Hsiu-Ju, Miller, Mitchell D., Elsliger, Marc-André, Deacon, Ashley M., Godzik, Adam, Lesley, Scott A., Tomoda, Kiichiro, Conklin, Bruce R., Wilson, Ian A., Yamanaka, Shinya, Fletterick, Robert J.
Published in Proceedings of the National Academy of Sciences - PNAS (14.04.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (14.04.2015)
Get full text
Journal Article
A gene-expression screen identifies a non-toxic sumoylation inhibitor that mimics SUMO-less human LRH-1 in liver
Suzawa, Miyuki, Miranda, Diego A, Ramos, Karmela A, Ang, Kenny K-H, Faivre, Emily J, Wilson, Christopher G, Caboni, Laura, Arkin, Michelle R, Kim, Yeong-Sang, Fletterick, Robert J, Diaz, Aaron, Schneekloth, John S, Ingraham, Holly A
Published in eLife (11.12.2015)
Published in eLife (11.12.2015)
Get full text
Journal Article
β‑Lactam Estrogen Receptor Antagonists and a Dual-Targeting Estrogen Receptor/Tubulin Ligand
O’Boyle, Niamh M, Pollock, Jade K, Carr, Miriam, Knox, Andrew J. S, Nathwani, Seema M, Wang, Shu, Caboni, Laura, Zisterer, Daniela M, Meegan, Mary J
Published in Journal of medicinal chemistry (26.11.2014)
Published in Journal of medicinal chemistry (26.11.2014)
Get full text
Journal Article
“True” AntiandrogensSelective Non-Ligand-Binding Pocket Disruptors of Androgen Receptor–Coactivator Interactions: Novel Tools for Prostate Cancer
Caboni, Laura, Kinsella, Gemma K, Blanco, Fernando, Fayne, Darren, Jagoe, William N, Carr, Miriam, Williams, D. Clive, Meegan, Mary J, Lloyd, David G
Published in Journal of medicinal chemistry (23.02.2012)
Published in Journal of medicinal chemistry (23.02.2012)
Get full text
Journal Article
Molecular Topology Applied to the Discovery of 1-Benzyl-2-(3-fluorophenyl)-4-hydroxy-3-(3-phenylpropanoyl)-2 H -pyrrole-5-one as a Non-Ligand-Binding-Pocket Antiandrogen
Caboni, Laura, Gálvez-Llompart, Maria, Gálvez, Jorge, Blanco, Fernando, Rubio-Martinez, Jaime, Fayne, Darren, Lloyd, David G.
Published in Journal of chemical information and modeling (27.10.2014)
Published in Journal of chemical information and modeling (27.10.2014)
Get full text
Journal Article
Molecular Topology Applied to the Discovery of 1‑Benzyl-2-(3-fluorophenyl)-4-hydroxy-3-(3-phenylpropanoyl)‑2H‑pyrrole-5-one as a Non-Ligand-Binding-Pocket Antiandrogen
Caboni, Laura, Gálvez-Llompart, Maria, Gálvez, Jorge, Blanco, Fernando, Rubio-Martinez, Jaime, Fayne, Darren, Lloyd, David G
Published in Journal of chemical information and modeling (27.10.2014)
Published in Journal of chemical information and modeling (27.10.2014)
Get full text
Journal Article
Structure–Activity Relationships in Non-Ligand Binding Pocket (Non-LBP) Diarylhydrazide Antiandrogens
Caboni, Laura, Egan, Billy, Kelly, Brendan, Blanco, Fernando, Fayne, Darren, Meegan, Mary J, Lloyd, David G
Published in Journal of chemical information and modeling (26.08.2013)
Published in Journal of chemical information and modeling (26.08.2013)
Get full text
Journal Article
Study of E/Z Isomerization in a Series of Novel Non-ligand Binding Pocket Androgen Receptor Antagonists
Blanco, Fernando, Egan, Billy, Caboni, Laura, Elguero, José, O’Brien, John, McCabe, Thomas, Fayne, Darren, Meegan, Mary J, Lloyd, David G
Published in Journal of chemical information and modeling (24.09.2012)
Published in Journal of chemical information and modeling (24.09.2012)
Get full text
Journal Article
Retinazone Inhibits Certain Blood-Borne Human Viruses Including Ebola Virus Zaire
Kesel, Andreas J, Huang, Zhuhui, Murray, Michael G, Prichard, Mark N, Caboni, Laura, Nevin, Daniel K, Fayne, Darren, Lloyd, David G, Detorio, Mervi A, Schinazi, Raymond F
Published in Antiviral chemistry & chemotherapy (01.10.2014)
Published in Antiviral chemistry & chemotherapy (01.10.2014)
Get full text
Journal Article
Consensus Computational Ligand-Based Design for the Identification of Novel Modulators of Human Estrogen Receptor Alpha
McKay, Paul B., Fayne, Darren, Horn, Hans W., James, Timothy, Peters, Martin B., Carta, Giorgio, Caboni, Laura, Nevin, Daniel K., Price, Trevor, Bradley, Geoff, Williams, D. Clive, Rice, Julia E., Lloyd, David G.
Published in Molecular informatics (01.04.2012)
Published in Molecular informatics (01.04.2012)
Get full text
Journal Article
Androgen receptor ligands
LLOYD DAVID GEORGE, CABONI LAURA, BLANCO FERNANDO, FAYNE DARREN, JAGOE WILIAM NICHOLAS, CARR MIRIAM, EGAN BILLY, MEEGAN MARY JANE, KINSELLA GEMMA KARENA, WILLIAMS D. CLIVE
Year of Publication 29.03.2016
Get full text
Year of Publication 29.03.2016
Patent
ANDROGEN RECEPTOR LIGANDS
LLOYD DAVID GEORGE, CABONI LAURA, BLANCO FERNANDO, FAYNE DARREN, JAGOE WILIAM NICHOLAS, CARR MIRIAM, EGAN BILLY, MEEGAN MARY JANE, KINSELLA GEMMA KARENA
Year of Publication 04.12.2014
Get full text
Year of Publication 04.12.2014
Patent
ANDROGEN RECEPTOR LIGANDS
LLOYD, DAVID GEORGE, CARR, MIRIAM, JAGOE, WILLIAM NICHOLAS, BLANCO, FERNANDO, FAYNE, DARREN, MEEGAN, MARY JANE, EGAN, BILLY, CABONI, LAURA, KINSELLA, GEMMA KARENA
Year of Publication 01.10.2014
Get full text
Year of Publication 01.10.2014
Patent
ANDROGEN RECEPTOR LIGANDS
LLOYD, DAVID GEORGE, CARR, MIRIAM, JAGOE, WILLIAM NICHOLAS, BLANCO, FERNANDO, FAYNE, DARREN, MEEGAN, MARY JANE, EGAN, BILLY, CABONI, LAURA, KINSELLA, GEMMA KARENA
Year of Publication 30.05.2013
Get full text
Year of Publication 30.05.2013
Patent