Toward the assembly and characterization of an encoded library hit confirmation platform: Bead-Assisted Ligand Isolation Mass Spectrometry (BALI-MS)
Ratnayake, Anokha S., Flanagan, Mark E., Foley, Timothy L., Hultgren, Scott L., Bellenger, Justin, Montgomery, Justin I., Lall, Manjinder S., Liu, Bo, Ryder, Tim, Kölmel, Dominik K., Shavnya, Andre, Feng, Xidong, Lefker, Bruce, Byrnes, Laura J., Sahasrabudhe, Parag V., Farley, Kathleen A., Chen, Shi, Wan, Jinqiao
Published in Bioorganic & medicinal chemistry (01.07.2021)
Published in Bioorganic & medicinal chemistry (01.07.2021)
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Circular permutation of red fluorescent proteins
Shui, Bo, Wang, Qi, Lee, Frank, Byrnes, Laura J, Chudakov, Dmitry M, Lukyanov, Sergey A, Sondermann, Holger, Kotlikoff, Michael I
Published in PloS one (27.05.2011)
Published in PloS one (27.05.2011)
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The Crystal Structures of Substrate and Nucleotide Complexes of Enterococcus faecium Aminoglycoside-2′′-Phosphotransferase-IIa [APH(2′′)-IIa] Provide Insights into Substrate Selectivity in the APH(2′′) Subfamily
YOUNG, Paul G, WALANJ, Rupa, LAKSHMI, Vendula, BYRNES, Laura J, METCALF, Peter, BAKER, Edward N, VAKULENKO, Sergei B, SMITH, Clyde A
Published in Journal of Bacteriology (01.07.2009)
Published in Journal of Bacteriology (01.07.2009)
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Molecular mechanism of a green-shifted, pH-dependent red fluorescent protein mKate variant
Wang, Qi, Byrnes, Laura J, Shui, Bo, Röhrig, Ute F, Singh, Avtar, Chudakov, Dmitriy M, Lukyanov, Sergey, Zipfel, Warren R, Kotlikoff, Michael I, Sondermann, Holger
Published in PloS one (22.08.2011)
Published in PloS one (22.08.2011)
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The hypervariable region of atlastin-1 is a site for intrinsic and extrinsic regulation
Kelly, Carolyn M, Byrnes, Laura J, Neela, Niharika, Sondermann, Holger, O'Donnell, John P
Published in The Journal of cell biology (01.11.2021)
Published in The Journal of cell biology (01.11.2021)
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The catalytic mechanism of cyclic GMP‐AMP synthase (cGAS) and implications for innate immunity and inhibition
Hall, Justin, Ralph, Erik C., Shanker, Suman, Wang, Hong, Byrnes, Laura J., Horst, Reto, Wong, Jimson, Brault, Amy, Dumlao, Darren, Smith, James F., Dakin, Leslie A., Schmitt, Daniel C., Trujillo, John, Vincent, Fabien, Griffor, Matt, Aulabaugh, Ann E.
Published in Protein science (01.12.2017)
Published in Protein science (01.12.2017)
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Discovery of High-Affinity Small-Molecule Binders of the Epigenetic Reader YEATS4
Londregan, Allyn T., Aitmakhanova, Karlygash, Bennett, James, Byrnes, Laura J., Canterbury, Daniel P., Cheng, Xiayun, Christott, Thomas, Clemens, Jennifer, Coffey, Steven B., Dias, João M., Dowling, Matthew S., Farnie, Gillian, Fedorov, Oleg, Fennell, Kimberly F., Gamble, Vicki, Gileadi, Carina, Giroud, Charline, Harris, Michael R., Hollingshead, Brett D., Huber, Kilian, Korczynska, Magdalena, Lapham, Kimberly, Loria, Paula M., Narayanan, Arjun, Owen, Dafydd R., Raux, Brigitt, Sahasrabudhe, Parag V., Ruggeri, Roger B., Sáez, Laura Díaz, Stock, Ingrid A., Thuma, Benjamin A., Tsai, Andy, Varghese, Alison E.
Published in Journal of medicinal chemistry (12.01.2023)
Published in Journal of medicinal chemistry (12.01.2023)
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Binding screen for cystic fibrosis transmembrane conductance regulator correctors finds new chemical matter and yields insights into cystic fibrosis therapeutic strategy
Hall, Justin D., Wang, Hong, Byrnes, Laura J., Shanker, Suman, Wang, Kelong, Efremov, Ivan V., Chong, P. Andrew, Forman‐Kay, Julie D., Aulabaugh, Ann E.
Published in Protein science (01.02.2016)
Published in Protein science (01.02.2016)
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Aminoglycoside 2''-phosphotransferase IIIa (APH(2'')-IIIa) prefers GTP over ATP: structural templates for nucleotide recognition in the bacterial aminoglycoside-2'' kinases
Smith, Clyde A, Toth, Marta, Frase, Hilary, Byrnes, Laura J, Vakulenko, Sergei B
Published in The Journal of biological chemistry (13.04.2012)
Published in The Journal of biological chemistry (13.04.2012)
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In vitro selection and analysis of SARS-CoV-2 nirmatrelvir resistance mutations contributing to clinical virus resistance surveillance
Zhu, Yuao, Yurgelonis, Irina, Noell, Stephen, Yang, Qingyi, Guan, Shunjie, Li, Zhenghui, Hao, Li, Rothan, Hussin, Rai, Devendra K., McMonagle, Patricia, Baniecki, Mary Lynn, Greasley, Samantha E., Plotnikova, Olga, Lee, Jonathan, Nicki, Jennifer A., Ferre, RoseAnn, Byrnes, Laura J., Liu, Wei, Craig, Timothy K., Steppan, Claire M., Liberator, Paul, Soares, Holly D., Allerton, Charlotte M. N., Anderson, Annaliesa S., Cardin, Rhonda D.
Published in Science advances (26.07.2024)
Published in Science advances (26.07.2024)
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Purification, crystallization and preliminary X-ray analysis of aminoglycoside-2′′-phosphotransferase-Ic [APH(2′′)-Ic] from Enterococcus gallinarum
Byrnes, Laura J., Badarau, Adriana, Vakulenko, Sergei B., Smith, Clyde A.
Published in Acta crystallographica. Section F, Structural biology and crystallization communications (01.02.2008)
Published in Acta crystallographica. Section F, Structural biology and crystallization communications (01.02.2008)
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The catalytic mechanism of cyclic GMP-AMP synthase (cGAS) and implications for innate immunity and inhibition: Catalytic Mechanism of cGAS
Hall, Justin, Ralph, Erik C., Shanker, Suman, Wang, Hong, Byrnes, Laura J., Horst, Reto, Wong, Jimson, Brault, Amy, Dumlao, Darren, Smith, James F., Dakin, Leslie A., Schmitt, Daniel C., Trujillo, John, Vincent, Fabien, Griffor, Matt, Aulabaugh, Ann E.
Published in Protein science (25.10.2017)
Published in Protein science (25.10.2017)
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Binding screen for cystic fibrosis transmembrane conductance regulator correctors finds new chemical matter and yields insights into cystic fibrosis therapeutic strategy: CFTR Correctors in CF Therapeutics
Hall, Justin D., Wang, Hong, Byrnes, Laura J., Shanker, Suman, Wang, Kelong, Efremov, Ivan V., Chong, P. Andrew, Forman-Kay, Julie D., Aulabaugh, Ann E.
Published in Protein science (01.02.2016)
Published in Protein science (01.02.2016)
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Aminoglycoside 2′′-Phosphotransferase IIIa (APH(2′′)-IIIa) Prefers GTP over ATP
Smith, Clyde A., Toth, Marta, Frase, Hilary, Byrnes, Laura J., Vakulenko, Sergei B.
Published in The Journal of biological chemistry (13.04.2012)
Published in The Journal of biological chemistry (13.04.2012)
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Journal Article
Aminoglycoside 2′′-Phosphotransferase IIIa (APH(2′′)-IIIa) Prefers GTP over ATP: STRUCTURAL TEMPLATES FOR NUCLEOTIDE RECOGNITION IN THE BACTERIAL AMINOGLYCOSIDE-2
Smith, Clyde A., Toth, Marta, Frase, Hilary, Byrnes, Laura J., Vakulenko, Sergei B.
Published in The Journal of biological chemistry (24.02.2012)
Published in The Journal of biological chemistry (24.02.2012)
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