Identification of candidate protective variants for common diseases and evaluation of their protective potential
Butler, Joe M, Hall, Neil, Narendran, Niro, Yang, Yit C, Paraoan, Luminita
Published in BMC genomics (03.08.2017)
Published in BMC genomics (03.08.2017)
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A combined transcriptomic approach to identify candidates for an anti-tick vaccine blocking B. afzelii transmission
Trentelman, Jos J. A., Sima, Radek, Krezdorn, Nicolas, Tomás-Cortázar, Julen, Barriales, Diego, Takumi, Katsuhisa, Butler, Joe M., Sprong, Hein, Klouwens, Michelle J., Urbanova, Veronika, Mahmood, Sazzad, Winter, Peter, Kopacek, Petr, Anguita, Juan, Hajdusek, Ondrej, Hovius, Joppe W.
Published in Scientific reports (18.11.2020)
Published in Scientific reports (18.11.2020)
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Journal Article
Sepsis: deriving biological meaning and clinical applications from high-dimensional data
Schuurman, Alex R., Reijnders, Tom D. Y., Kullberg, Robert F. J., Butler, Joe M., van der Poll, Tom, Wiersinga, W. Joost
Published in Intensive care medicine experimental (07.05.2021)
Published in Intensive care medicine experimental (07.05.2021)
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Journal Article
CEBPD Potentiates the Macrophage Inflammatory Response but CEBPD Knock-Out Macrophages Fail to Identify CEBPD-Dependent Pro-Inflammatory Transcriptional Programs
Spek, C. Arnold, Aberson, Hella L., Butler, Joe M., de Vos, Alex F., Duitman, JanWillem
Published in Cells (Basel, Switzerland) (28.08.2021)
Published in Cells (Basel, Switzerland) (28.08.2021)
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Journal Article
HIVEP1 Is a Negative Regulator of NF-κB That Inhibits Systemic Inflammation in Sepsis
Matsumoto, Hisatake, Scicluna, Brendon P, Jim, Kin Ki, Falahi, Fahimeh, Qin, Wanhai, Gürkan, Berke, Malmström, Erik, Meijer, Mariska T, Butler, Joe M, Khan, Hina N, Takagi, Tsuyoshi, Ishii, Shunsuke, Schultz, Marcus J, van de Beek, Diederik, de Vos, Alex F, van 't Veer, Cornelis, van der Poll, Tom
Published in Frontiers in immunology (05.11.2021)
Published in Frontiers in immunology (05.11.2021)
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Journal Article
Single-cell transcriptomics reveals subset-specific metabolic profiles underpinning the bronchial epithelial response to flagellin
Ramirez-Moral, Ivan, Schuurman, Alex R., van Linge, Christine C.A., Butler, Joe M., Yu, Xiao, de Haan, Karen, van Leeuwen, Sarah, de Vos, Alex F., de Jong, Menno D., Vieira Braga, Felipe A., van der Poll, Tom
Published in iScience (20.09.2024)
Published in iScience (20.09.2024)
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Journal Article
Role of Myeloid Tet Methylcytosine Dioxygenase 2 in Pulmonary and Peritoneal Inflammation Induced by Lipopolysaccharide and Peritonitis Induced by Escherichia coli
Qin, Wanhai, Brands, Xanthe, Matsumoto, Hisatake, Butler, Joe M, Van't Veer, Cornelis, de Vos, Alex F, Roelofs, Joris J T H, Scicluna, Brendon P, van der Poll, Tom
Published in Cells (Basel, Switzerland) (28.12.2021)
Published in Cells (Basel, Switzerland) (28.12.2021)
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Journal Article
C/EBPδ Suppresses Motility-Associated Gene Signatures and Reduces PDAC Cell Migration
Hartl, Leonie, Maarschalkerweerd, Pien A F, Butler, Joe M, Manz, Xue D, Thijssen, Victor L J L, Bijlsma, Maarten F, Duitman, JanWillem, Spek, C Arnold
Published in Cells (Basel, Switzerland) (22.10.2022)
Published in Cells (Basel, Switzerland) (22.10.2022)
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Journal Article
Inflammatory and glycolytic programs underpin a primed blood neutrophil state in patients with pneumonia
Schuurman, Alex R., Butler, Joe M., Michels, Erik H.A., Otto, Natasja A., Brands, Xanthe, Haak, Bastiaan W., Uhel, Fabrice, Klarenbeek, Augustijn M., Faber, Daniël R., Schomakers, Bauke V., van Weeghel, Michel, de Vos, Alex F., Scicluna, Brendon P., Houtkooper, Riekelt H., Wiersinga, W. Joost, van der Poll, Tom
Published in iScience (21.07.2023)
Published in iScience (21.07.2023)
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Journal Article
Rectal microbiota are coupled with altered cytokine production capacity following community-acquired pneumonia hospitalization
Kullberg, Robert F.J., Brands, Xanthe, Klarenbeek, Augustijn M., Butler, Joe M., Otto, Natasja A., Faber, Daniël R., Scicluna, Brendon P., van der Poll, Tom, Wiersinga, W. Joost, Haak, Bastiaan W.
Published in iScience (19.08.2022)
Published in iScience (19.08.2022)
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Journal Article
Rectal bacteriome and virome signatures and clinical outcomes in community-acquired pneumonia: An exploratory study
Kullberg, Robert F.J., Hugenholtz, Floor, Brands, Xanthe, Kinsella, Cormac M., Peters-Sengers, Hessel, Butler, Joe M., Deijs, Martin, Klein, Michelle, Faber, Daniël R., Scicluna, Brendon P., Van der Poll, Tom, Van der Hoek, Lia, Wiersinga, W. Joost, Haak, Bastiaan W.
Published in EClinicalMedicine (01.09.2021)
Published in EClinicalMedicine (01.09.2021)
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Journal Article
HIF-1α Stabilization in Flagellin-Stimulated Human Bronchial Cells Impairs Barrier Function
Ramirez-Moral, Ivan, Ferreira, Bianca L, Butler, Joe M, van Weeghel, Michel, Otto, Natasja A, de Vos, Alex F, Yu, Xiao, de Jong, Menno D, Houtkooper, Riekelt H, van der Poll, Tom
Published in Cells (Basel, Switzerland) (24.01.2022)
Published in Cells (Basel, Switzerland) (24.01.2022)
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Journal Article
Adherence Affects Monocyte Innate Immune Function and Metabolic Reprogramming after Lipopolysaccharide Stimulation In Vitro
Otto, Natasja A, Butler, Joe M, Ramirez-Moral, Ivan, van Weeghel, Michel, van Heijst, Jeroen W J, Scicluna, Brendon P, Houtkooper, Riekelt H, de Vos, Alex F, van der Poll, Tom
Published in The Journal of immunology (1950) (15.02.2021)
Published in The Journal of immunology (1950) (15.02.2021)
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Journal Article
Uncovering heterogeneity in sepsis: a comparative analysis of subphenotypes
van Amstel, Rombout B. E., Kennedy, Jason N., Scicluna, Brendon P., Bos, Lieuwe D. J., Peters-Sengers, Hessel, Butler, Joe M., Cano-Gamez, Eddie, Knight, Julian C., Vlaar, Alexander P. J., Cremer, Olaf L., Angus, Derek C., van der Poll, Tom, Seymour, Christopher W., van Vught, Lonneke A.
Published in Intensive care medicine (01.11.2023)
Published in Intensive care medicine (01.11.2023)
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Journal Article
Source-specific host response and outcomes in critically ill patients with sepsis: a prospective cohort study
Peters-Sengers, Hessel, Butler, Joe M., Uhel, Fabrice, Schultz, Marcus J., Bonten, Marc J., Cremer, Olaf L., Scicluna, Brendon P., van Vught, Lonneke A., van der Poll, Tom
Published in Intensive care medicine (01.01.2022)
Published in Intensive care medicine (01.01.2022)
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Journal Article
Monocyte state 1 (MS1) cells in critically ill patients with sepsis or non-infectious conditions: association with disease course and host response
Leite, Giuseppe G F, de Brabander, Justin, Michels, Erik H A, Butler, Joe M, Cremer, Olaf L, Scicluna, Brendon P, Sweeney, Timothy E, Reyes, Miguel, Salomao, Reinaldo, Peters-Sengers, Hessel, van der Poll, Tom
Published in Critical care (London, England) (19.03.2024)
Published in Critical care (London, England) (19.03.2024)
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Journal Article
The Plasma Lipidomic Landscape in Patients with Sepsis due to Community-acquired Pneumonia
Chouchane, Osoul, Schuurman, Alex R, Reijnders, Tom D Y, Peters-Sengers, Hessel, Butler, Joe M, Uhel, Fabrice, Schultz, Marcus J, Bonten, Marc J, Cremer, Olaf L, Calfee, Carolyn S, Matthay, Michael A, Langley, Raymond J, Alipanah-Lechner, Narges, Kingsmore, Stephen F, Rogers, Angela, van Weeghel, Michel, Vaz, Frédéric M, van der Poll, Tom
Published in American journal of respiratory and critical care medicine (15.04.2024)
Published in American journal of respiratory and critical care medicine (15.04.2024)
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Journal Article
Human alveolar macrophages do not rely on glucose metabolism upon activation by lipopolysaccharide
Pereverzeva, Liza, van Linge, Christine C.A., Schuurman, Alex R., Klarenbeek, Augustijn M., Ramirez Moral, Ivan, Otto, Natasja A., Peters-Sengers, Hessel, Butler, Joe M., Schomakers, Bauke V., van Weeghel, Michel, Houtkooper, Riekelt H., Wiersinga, W. Joost, Bonta, Peter I., Annema, Jouke T., de Vos, Alex F., van der Poll, Tom
Published in Biochimica et biophysica acta. Molecular basis of disease (01.10.2022)
Published in Biochimica et biophysica acta. Molecular basis of disease (01.10.2022)
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Journal Article
Intracellular pyruvate levels positively correlate with cytokine production capacity in tolerant monocytes from patients with pneumonia
Otto, Natasja A., Butler, Joe M., Schuurman, Alex R., Brands, Xanthe, Haak, Bastiaan W., Klarenbeek, Augustijn M., van Weeghel, Michel, Houtkooper, Riekelt H., Jakobs, Marja E., Faber, Daniël R., de Vos, Alex F., Wiersinga, W. Joost, Scicluna, Brendon P., van der Poll, Tom
Published in Biochimica et biophysica acta. Molecular basis of disease (01.11.2022)
Published in Biochimica et biophysica acta. Molecular basis of disease (01.11.2022)
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