A practical, multi-gram synthesis of (±)-herbindole A, (±)-herbindole B, and (±)-herbindole C from a common intermediate via 6,7-indole aryne cycloaddition and Pd(0)-catalyzed cross-coupling reactions
Chandrasoma, Nalin, Pathmanathan, Sivadarshini, Buszek, Keith R.
Published in Tetrahedron letters (03.06.2015)
Published in Tetrahedron letters (03.06.2015)
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Application of 6,7-Indole Aryne Cycloaddition and Pd(0)-Catalyzed Suzuki–Miyaura and Buchwald–Hartwig Cross-Coupling Reactions for the Preparation of Annulated Indole Libraries
Thornton, Paul D, Brown, Neil, Hill, David, Neuenswander, Ben, Lushington, Gerald H, Santini, Conrad, Buszek, Keith R
Published in ACS combinatorial science (12.09.2011)
Published in ACS combinatorial science (12.09.2011)
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Experimental and Theoretical Investigations into the Unusual Regioselectivity of 4,5-, 5,6-, and 6,7-Indole Aryne Cycloadditions
Garr, Ashley N, Luo, Diheng, Brown, Neil, Cramer, Christopher J, Buszek, Keith R, VanderVelde, David
Published in Organic letters (01.01.2010)
Published in Organic letters (01.01.2010)
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Indole-Derived Arynes and Their Diels−Alder Reactivity with Furans
Buszek, Keith R, Luo, Diheng, Kondrashov, Mikhail, Brown, Neil, VanderVelde, David
Published in Organic letters (11.10.2007)
Published in Organic letters (11.10.2007)
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Total synthesis of halichondrin B and norhalichondrin B
Aicher, Thomas D, Buszek, Keith R, Fang, Francis G, Forsyth, Craig J, Jung, Sun Ho, Kishi, Yoshito, Matelich, Michael C, Scola, Paul M, Spero, Denice M, Yoon, Suk Kyoon
Published in Journal of the American Chemical Society (01.04.1992)
Published in Journal of the American Chemical Society (01.04.1992)
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Distinguishing the Chemical Moiety of Phosphoenolpyruvate That Contributes to Allostery in Muscle Pyruvate Kinase
Urness, James M, Clapp, Kelly M, Timmons, J. Cody, Bai, Xinyan, Chandrasoma, Nalin, Buszek, Keith R, Fenton, Aron W
Published in Biochemistry (Easton) (08.01.2013)
Published in Biochemistry (Easton) (08.01.2013)
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Mechanisms by which synthetic 6,7-annulated-4-substituted indole compounds with anti-proliferative activity disrupt mitosis and block cytokinesis in human HL-60 tumor cells in vitro
Perchellet, Jean-Pierre H, Perchellet, Elisabeth M, Singh, Chingakham Ranjit, Monnett, Meghan T, Studer, Elizabeth R, Thornton, Paul D, Brown, Neil, Hill, David, Neuenswander, Ben, Lushington, Gerald H, Santini, Conrad, Buszek, Keith R
Published in Anticancer research (01.04.2014)
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Published in Anticancer research (01.04.2014)
Journal Article
Antitumor Effects of Synthetic 6,7-Annulated-4-substituted Indole Compounds in L1210 Leukemic Cells In Vitro
PERCHELLET, Jean-Pierre H, WATERS, Andrew M, BUSZEK, Keith R, PERCHELLET, Elisabeth M, THORNTON, Paul D, BROWN, Neil, HILL, David, NEUENSWANDER, Ben, LUSHINGTON, Gerald H, SANTINI, Conrad, CHANDRASOMA, Nalin
Published in Anticancer research (01.11.2012)
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Published in Anticancer research (01.11.2012)
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Synthesis of a natural product-inspired eight-membered ring lactam library via ring-closing metathesis
Brown, Neil, Xie, Baohan, Markina, Nataliya, VanderVelde, David, Perchellet, Jean-Pierre H., Perchellet, Elisabeth M., Crow, Kyle R., Buszek, Keith R.
Published in Bioorganic & medicinal chemistry (01.09.2008)
Published in Bioorganic & medicinal chemistry (01.09.2008)
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Novel synthetic inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase activity that inhibit tumor cell proliferation and are structurally unrelated to existing statins
Perchellet, Jean-Pierre, Perchellet, Elisabeth, Crow, Kyle, Buszek, Keith, Brown, Neil, Ellappan, Sampathkumar, Gao, Ge, Luo, Diheng, Minatoya, Machiko, Lushington, Gerald
Published in International journal of molecular medicine (01.11.2009)
Published in International journal of molecular medicine (01.11.2009)
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Journal Article
Total Synthesis of Octalactin A and B
Buszek, Keith R, Sato, Nagaaki, Jeong, Youngmee
Published in Journal of the American Chemical Society (01.06.1994)
Published in Journal of the American Chemical Society (01.06.1994)
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