5-Lipoxygenase is a candidate target for therapeutic management of stem cell-like cells in acute myeloid leukemia
Roos, Jessica, Oancea, Claudia, Heinssmann, Maria, Khan, Dilawar, Held, Hannelore, Kahnt, Astrid S, Capelo, Ricardo, la Buscató, Estel, Proschak, Ewgenij, Puccetti, Elena, Steinhilber, Dieter, Fleming, Ingrid, Maier, Thorsten J, Ruthardt, Martin
Published in Cancer research (Chicago, Ill.) (15.09.2014)
Published in Cancer research (Chicago, Ill.) (15.09.2014)
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Structure–Activity Relationship of Nonacidic Quinazolinone Inhibitors of Human Microsomal Prostaglandin Synthase 1 (mPGES 1)
Rörsch, Florian, Buscató, Estel.la, Deckmann, Klaus, Schneider, Gisbert, Schubert-Zsilavecz, Manfred, Geisslinger, Gerd, Proschak, Ewgenij, Grösch, Sabine
Published in Journal of medicinal chemistry (26.04.2012)
Published in Journal of medicinal chemistry (26.04.2012)
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SAR-study on a new class of imidazo[1,2-a]pyridine-based inhibitors of 5-lipoxygenase
Hieke, Martina, Rödl, Carmen B., Wisniewska, Joanna M., la Buscató, Estel, Stark, Holger, Schubert-Zsilavecz, Manfred, Steinhilber, Dieter, Hofmann, Bettina, Proschak, Ewgenij
Published in Bioorganic & medicinal chemistry letters (01.03.2012)
Published in Bioorganic & medicinal chemistry letters (01.03.2012)
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Evaluation of structure-derived pharmacophore of soluble epoxide hydrolase inhibitors by virtual screening
Moser, Daniel, Achenbach, Janosch, Klingler, Franca-Maria, Estel la, Buscató, Hahn, Steffen, Proschak, Ewgenij
Published in Bioorganic & medicinal chemistry letters (01.11.2012)
Published in Bioorganic & medicinal chemistry letters (01.11.2012)
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Synthesis and Structure–Activity Relationship Studies of Novel Dual Inhibitors of Soluble Epoxide Hydrolase and 5‑Lipoxygenase
Meirer, Karin, Rödl, Carmen B, Wisniewska, Joanna M, George, Sven, Häfner, Ann-Kathrin, Buscató, Estel·la, Klingler, Franca-Maria, Hahn, Steffen, Berressem, Dirk, Wittmann, Sandra K, Steinhilber, Dieter, Hofmann, Bettina, Proschak, Ewgenij
Published in Journal of medicinal chemistry (28.02.2013)
Published in Journal of medicinal chemistry (28.02.2013)
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Design and Synthesis of Dual Modulators of Soluble Epoxide Hydrolase and Peroxisome Proliferator-Activated Receptors
Buscató, Estel.la, Blöcher, René, Lamers, Christina, Klingler, Franca-Maria, Hahn, Steffen, Steinhilber, Dieter, Schubert-Zsilavecz, Manfred, Proschak, Ewgenij
Published in Journal of medicinal chemistry (13.12.2012)
Published in Journal of medicinal chemistry (13.12.2012)
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5-Lipoxygenase inhibitors: a patent evaluation (WO2011161615)
Buscató, Estel la, Proschak, Ewgenij
Published in Expert opinion on therapeutic patents (01.07.2012)
Published in Expert opinion on therapeutic patents (01.07.2012)
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Structure-activity relationship and in vitro pharmacological evaluation of imidazo[1,2-a]pyridine-based inhibitors of 5-LO
Buscató, Estel la, Wisniewska, Joanna M, Rödl, Carmen B, Brüggerhoff, Astrid, Kaiser, Astrid, Rörsch, Florian, Kostewicz, Edmund, Wurglics, Mario, Schubert-Zsilavecz, Manfred, Grösch, Sabine, Steinhilber, Dieter, Hofmann, Bettina, Proschak, Ewgenij
Published in Future medicinal chemistry (01.05.2013)
Published in Future medicinal chemistry (01.05.2013)
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Design of dual ligands using excessive pharmacophore query alignment
Moser, Daniel, Wisniewska, Joanna, Hahn, Steffen, la Buscató, Estel, Klingler, Franca-Maria, Achenbach, Janosch, Hofmann, Bettina, Steinhilber, Dieter, Proschak, Ewgenij
Published in Journal of cheminformatics (01.05.2012)
Published in Journal of cheminformatics (01.05.2012)
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Zafirlukast Is a Dual Modulator of Human Soluble Epoxide Hydrolase and Peroxisome Proliferator-Activated Receptor γ
Göbel, Tamara, Diehl, Olaf, Heering, Jan, Merk, Daniel, Angioni, Carlo, Wittmann, Sandra K, Buscato, Estel la, Kottke, Ramona, Weizel, Lilia, Schader, Tim, Maier, Thorsten J, Geisslinger, Gerd, Schubert-Zsilavecz, Manfred, Steinhilber, Dieter, Proschak, Ewgenij, Kahnt, Astrid S
Published in Frontiers in pharmacology (20.03.2019)
Published in Frontiers in pharmacology (20.03.2019)
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Molecular characterization of EP6—A novel imidazo[1,2- a]pyridine based direct 5-lipoxygenase inhibitor
Wisniewska, Joanna M., Rödl, Carmen B., Kahnt, Astrid S., Buscató, Estel.la, Ulrich, Sandra, Tanrikulu, Yusuf, Achenbach, Janosch, Rörsch, Florian, Grösch, Sabine, Schneider, Gisbert, Cinatl, Jindrich, Proschak, Ewgenij, Steinhilber, Dieter, Hofmann, Bettina
Published in Biochemical pharmacology (15.01.2012)
Published in Biochemical pharmacology (15.01.2012)
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From a Multipotent Stilbene to Soluble Epoxide Hydrolase Inhibitors with Antiproliferative Properties
Buscató, Estel.la, Büttner, Dominik, Brüggerhoff, Astrid, Klingler, Franca-Maria, Weber, Julia, Scholz, Bastian, Živković, Aleksandra, Marschalek, Rolf, Stark, Holger, Steinhilber, Dieter, Bode, Helge B., Proschak, Ewgenij
Published in ChemMedChem (01.06.2013)
Published in ChemMedChem (01.06.2013)
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PADI4 acts as a coactivator of Tal1 by counteracting repressive histone arginine methylation
Kolodziej, Stephan, Kuvardina, Olga N, Oellerich, Thomas, Herglotz, Julia, Backert, Ingo, Kohrs, Nicole, Buscató, Estel la, Wittmann, Sandra K, Salinas-Riester, Gabriela, Bonig, Halvard, Karas, Michael, Serve, Hubert, Proschak, Ewgenij, Lausen, Jörn
Published in Nature communications (29.05.2014)
Published in Nature communications (29.05.2014)
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Dual-Target Virtual Screening by Pharmacophore Elucidation and Molecular Shape Filtering
Moser, Daniel, Wisniewska, Joanna M, Hahn, Steffen, Achenbach, Janosch, Buscató, Estel·la, Klingler, Franca-Maria, Hofmann, Bettina, Steinhilber, Dieter, Proschak, Ewgenij
Published in ACS medicinal chemistry letters (09.02.2012)
Published in ACS medicinal chemistry letters (09.02.2012)
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