Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans
Taskinen, Marja-Riitta, Melander, Olle, Tai, E Shyong, Rieder, Mark J, Groop, Leif, Corella, Dolores, Surti, Aarti, Jousilahti, Pekka, Kathiresan, Sekar, Hedblad, Bo, Burtt, Noël P, Peltonen, Leena, Berglund, Göran, Havulinna, Aki S, Hedner, Thomas, Ordovas, Jose M, Orho-Melander, Marju, Salomaa, Veikko, Cooper, Gregory M, Wahlstrand, Björn, Roos, Charlotta, Guiducci, Candace, Altshuler, David M, Voight, Benjamin F, Vartiainen, Erkki, Newton-Cheh, Christopher
Published in Nature genetics (01.02.2008)
Published in Nature genetics (01.02.2008)
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Common Single Nucleotide Polymorphisms in TCF7L2 Are Reproducibly Associated With Type 2 Diabetes and Reduce the Insulin Response to Glucose in Nondiabetic Individuals
SAXENA, Richa, GIANNINY, Lauren, LINDBLAD, Ulf, DALY, Mark J, TUOMI, Tiinamaija, HIRSCHHORN, Joel N, ARDLIE, Kristin G, GROOP, Leif C, ALTSHULER, David, BURTT, Noël P, LYSSENKO, Valeriya, GIUDUCCI, Candace, SJÖGREN, Marketa, FLOREZ, Jose C, ALMGREN, Peter, ISOMAA, Bo, ORHO-MELANDER, Marju
Published in Diabetes (New York, N.Y.) (01.10.2006)
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Polymorphisms Associated with Cholesterol and Risk of Cardiovascular Events
Kathiresan, Sekar, Melander, Olle, Anevski, Dragi, Guiducci, Candace, Burtt, Noël P, Roos, Charlotta, Hirschhorn, Joel N, Berglund, Göran, Hedblad, Bo, Groop, Leif, Altshuler, David M, Newton-Cheh, Christopher, Orho-Melander, Marju
Published in The New England journal of medicine (20.03.2008)
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Leveraging type 1 diabetes human genetic and genomic data in the T1D knowledge portal
Kudtarkar, Parul, Costanzo, Maria C, Sun, Ying, Jang, Dongkeun, Koesterer, Ryan, Mychaleckyj, Josyf C, Nayak, Uma, Onengut-Gumuscu, Suna, Rich, Stephen S, Flannick, Jason A, Gaulton, Kyle J, Burtt, Noël P
Published in PLoS biology (10.08.2023)
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Mapping genomic regulation of kidney disease and traits through high-resolution and interpretable eQTLs
Han, Seong Kyu, McNulty, Michelle T, Benway, Christopher J, Wen, Pei, Greenberg, Anya, Onuchic-Whitford, Ana C, Jang, Dongkeun, Flannick, Jason, Burtt, Noël P, Wilson, Parker C, Humphreys, Benjamin D, Wen, Xiaoquan, Han, Zhe, Lee, Dongwon, Sampson, Matthew G
Published in Nature communications (19.04.2023)
Published in Nature communications (19.04.2023)
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The Lipid Droplet Knowledge Portal: A resource for systematic analyses of lipid droplet biology
Mejhert, Niklas, Gabriel, Katlyn R, Frendo-Cumbo, Scott, Krahmer, Natalie, Song, Jiunn, Kuruvilla, Leena, Chitraju, Chandramohan, Boland, Sebastian, Jang, Dong-Keun, von Grotthuss, Marcin, Costanzo, Maria C, Rydén, Mikael, Olzmann, James A, Flannick, Jason, Burtt, Noël P, Farese, Jr, Robert V, Walther, Tobias C
Published in Developmental cell (07.02.2022)
Published in Developmental cell (07.02.2022)
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High-throughput, pooled sequencing identifies mutations in NUBPL and FOXRED1 in human complex I deficiency
Thorburn, David R, Mootha, Vamsi K, Calvo, Sarah E, Tucker, Elena J, Compton, Alison G, Kirby, Denise M, Crawford, Gabriel, Burtt, Noel P, Rivas, Manuel, Guiducci, Candace, Bruno, Damien L, Goldberger, Olga A, Redman, Michelle C, Wiltshire, Esko, Wilson, Callum J, Altshuler, David, Gabriel, Stacey B, Daly, Mark J
Published in Nature genetics (01.10.2010)
Published in Nature genetics (01.10.2010)
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Rare coding variant analysis for human diseases across biobanks and ancestries
Jurgens, Sean J., Wang, Xin, Choi, Seung Hoan, Weng, Lu-Chen, Koyama, Satoshi, Pirruccello, James P., Nguyen, Trang, Smadbeck, Patrick, Jang, Dongkeun, Chaffin, Mark, Walsh, Roddy, Roselli, Carolina, Elliott, Amanda L., Wijdeveld, Leonoor F. J. M., Biddinger, Kiran J., Kany, Shinwan, Rämö, Joel T., Natarajan, Pradeep, Aragam, Krishna G., Flannick, Jason, Burtt, Noël P., Bezzina, Connie R., Lubitz, Steven A., Lunetta, Kathryn L., Ellinor, Patrick T.
Published in Nature genetics (29.08.2024)
Published in Nature genetics (29.08.2024)
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Phenome- and genome-wide analyses of retinal optical coherence tomography images identify links between ocular and systemic health
Zekavat, Seyedeh Maryam, Jorshery, Saman Doroodgar, Rauscher, Franziska G, Horn, Katrin, Sekimitsu, Sayuri, Koyama, Satoshi, Nguyen, Trang T, Costanzo, Maria C, Jang, Dongkeun, Burtt, Noël P, Kühnapfel, Andreas, Shweikh, Yusrah, Ye, Yixuan, Raghu, Vineet, Zhao, Hongyu, Ghassemi, Marzyeh, Elze, Tobias, Segrè, Ayellet V, Wiggs, Janey L, Del Priore, Lucian, Scholz, Markus, Wang, Jay C, Natarajan, Pradeep, Zebardast, Nazlee
Published in Science translational medicine (24.01.2024)
Published in Science translational medicine (24.01.2024)
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Comparing strategies to fine-map the association of common SNPs at chromosome 9p21 with type 2 diabetes and myocardial infarction
SHEA, Jessica, AGARWALA, Vineeta, GABRIEL, Stacey, BURTT, Noel P, DALY, Mark J, GROOP, Leif, ALTSHULER, David, PHILIPPAKIS, Anthony A, MAGUIRE, Jared, BANKS, Eric, DEPRISTO, Mark, THOMSON, Brian, GUIDUCCI, Candace, ONOFRIO, Robert C, KATHIRESAN, Sekar
Published in Nature genetics (01.08.2011)
Published in Nature genetics (01.08.2011)
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Cardiovascular Disease Knowledge Portal: A Community Resource for Cardiovascular Disease Research
Costanzo, Maria C, Roselli, Carolina, Brandes, MacKenzie, Duby, Marc, Hoang, Quy, Jang, Dongkeun, Koesterer, Ryan, Kudtarkar, Parul, Moriondo, Annie, Nguyen, Trang, Ruebenacker, Oliver, Smadbeck, Patrick, Sun, Ying, Butterworth, Adam S, Aragam, Krishna G, Lumbers, R Thomas, Khera, Amit V, Lubitz, Steven A, Ellinor, Patrick T, Gaulton, Kyle J, Flannick, Jason, Burtt, Noël P
Published in Circulation. Genomic and precision medicine (01.12.2023)
Published in Circulation. Genomic and precision medicine (01.12.2023)
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IGF2R Missense Single-Nucleotide Polymorphisms and Breast Cancer Risk: The Multiethnic Cohort Study
CHENG, Iona, STRAM, Daniel O, BURTT, Noël P, GIANNINY, Lauren, GARCIA, Rachel R, POOLER, Loreall, HENDERSON, Brian E, LE MARCHAND, Loïc, HAIMAN, Christopher A
Published in Cancer epidemiology, biomarkers & prevention (01.06.2009)
Published in Cancer epidemiology, biomarkers & prevention (01.06.2009)
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The Krüppel-Like Factor 11 (KLF11) Q62R Polymorphism Is Not Associated With Type 2 Diabetes in 8,676 People
FLOREZ, Jose C, SAXENA, Richa, ALTSHULER, David, HIRSCHHORN, Joel N, GROOP, Leif, WINCKLER, Wendy, BURTT, Noël P, ALMGREN, Peter, BENGTSSON BOSTRÖM, Kristina, TUOMI, Tiinamaija, GAUDET, Daniel, ARDLIE, Kristin G, DALY, Mark J
Published in Diabetes (New York, N.Y.) (01.12.2006)
Published in Diabetes (New York, N.Y.) (01.12.2006)
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Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus
Behrens, Timothy W, Lessard, Christopher J, Cotsapas, Chris, Burtt, Noel P, Vyse, Timothy J, Davies, Leela, Hackett, Rachel, Leon, Joanlise M, Rioux, John D, Daly, Mark J, Altshuler, David, Gaffney, Patrick M, Cunninghame Graham, Deborah, Plenge, Robert M, Graham, Robert R, Parkin, Melissa, Gates, Casey, Moser, Kathy L, Wither, Joan E, Fortin, Paul R, Guiducci, Candace, Wong, Andrew K
Published in Nature genetics (01.09.2008)
Published in Nature genetics (01.09.2008)
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The Musculoskeletal Knowledge Portal: improving access to multi-omics data
Westendorf, Jennifer J, Bonewald, Lynda F, Kiel, Douglas P, Burtt, Noël P
Published in Nature reviews. Rheumatology (01.01.2022)
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A comprehensive analysis of common genetic variation in prolactin (PRL) and PRL receptor (PRLR) genes in relation to plasma prolactin levels and breast cancer risk: the multiethnic cohort
Lee, Sulggi A, Haiman, Christopher A, Burtt, Noel P, Pooler, Loreall C, Cheng, Iona, Kolonel, Laurence N, Pike, Malcolm C, Altshuler, David, Hirschhorn, Joel N, Henderson, Brian E, Stram, Daniel O
Published in BMC medical genetics (01.12.2007)
Published in BMC medical genetics (01.12.2007)
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A common variant of HMGA2 is associated with adult and childhood height in the general population
Shields, Beverley, Salomaa, Veikko, Burtt, Noel P, Weedon, Michael N, Voight, Benjamin F, Tobias, Jonathan H, Guiducci, Candace, Morris, Andrew D, Perry, John R B, Ness, Andrew R, Lango, Hana, Frayling, Timothy M, Lettre, Guillaume, Elliott, Katherine S, Groop, Leif C, Palmer, Colin N A, Hirschhorn, Joel N, Zeggini, Eleftheria, Lindgren, Cecilia M, Freathy, Rachel M, Timpson, Nicholas J, Peltonen, Leena, Hackett, Rachel, Lyssenko, Valeriya, Rayner, Nigel W, McCarthy, Mark I, Ardlie, Kristin, Ring, Susan M, Saxena, Richa, Smith, George Davey, Hattersley, Andrew T
Published in Nature genetics (01.10.2007)
Published in Nature genetics (01.10.2007)
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Power in the phenotypic extremes: a simulation study of power in discovery and replication of rare variants
Guey, Lin T., Kravic, Jasmina, Melander, Olle, Burtt, Noël P., Laramie, Jason M., Lyssenko, Valeriya, Jonsson, Anna, Lindholm, Eero, Tuomi, Tiinamaija, Isomaa, Bo, Nilsson, Peter, Almgren, Peter, Kathiresan, Sekar, Groop, Leif, Seymour, Albert B., Altshuler, David, Voight, Benjamin F.
Published in Genetic epidemiology (01.05.2011)
Published in Genetic epidemiology (01.05.2011)
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A genome-wide association study for blood lipid phenotypes in the Framingham Heart Study
Kathiresan, Sekar, Manning, Alisa K, Demissie, Serkalem, D'Agostino, Ralph B, Surti, Aarti, Guiducci, Candace, Gianniny, Lauren, Burtt, Nöel P, Melander, Olle, Orho-Melander, Marju, Arnett, Donna K, Peloso, Gina M, Ordovas, Jose M, Cupples, L Adrienne
Published in BMC medical genetics (19.09.2007)
Published in BMC medical genetics (19.09.2007)
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Assessing the phenotypic effects in the general population of rare variants in genes for a dominant Mendelian form of diabetes
Flannick, Jason, Beer, Nicola L, Bick, Alexander G, Agarwala, Vineeta, Molnes, Janne, Gupta, Namrata, Burtt, Noël P, Florez, Jose C, Meigs, James B, Taylor, Herman, Lyssenko, Valeriya, Irgens, Henrik, Fox, Ervin, Burslem, Frank, Johansson, Stefan, Brosnan, M Julia, Trimmer, Jeff K, Newton-Cheh, Christopher, Tuomi, Tiinamaija, Molven, Anders, Wilson, James G, O'Donnell, Christopher J, Kathiresan, Sekar, Hirschhorn, Joel N, Njølstad, Pål R, Rolph, Tim, Seidman, J G, Gabriel, Stacey, Cox, David R, Seidman, Christine E, Groop, Leif, Altshuler, David
Published in Nature genetics (01.11.2013)
Published in Nature genetics (01.11.2013)
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