A rapid in vivo pipeline to identify small molecule inhibitors of amyloid aggregation
Kamal, Muntasir, Knox, Jessica, Horne, Robert I., Tiwari, Om Shanker, Burns, Andrew R., Han, Duhyun, Levy, Davide, Laor Bar-Yosef, Dana, Gazit, Ehud, Vendruscolo, Michele, Roy, Peter J.
Published in Nature communications (27.09.2024)
Published in Nature communications (27.09.2024)
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Journal Article
Nemacol is a small molecule inhibitor of C. elegans vesicular acetylcholine transporter with anthelmintic potential
Harrington, Sean, Pyche, Jacob, Burns, Andrew R., Spalholz, Tina, Ryan, Kaetlyn T., Baker, Rachel J., Ching, Justin, Rufener, Lucien, Lautens, Mark, Kulke, Daniel, Vernudachi, Alexandre, Zamanian, Mostafa, Deuther-Conrad, Winnie, Brust, Peter, Roy, Peter J.
Published in Nature communications (31.03.2023)
Published in Nature communications (31.03.2023)
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Journal Article
PGP-14 establishes a polar lipid permeability barrier within the C. elegans pharyngeal cuticle
Kamal, Muntasir, Tokmakjian, Levon, Knox, Jessica, Han, Duhyun, Moshiri, Houtan, Magomedova, Lilia, Nguyen, Ken Cq, Zheng, Hong, Burns, Andrew R, Cooke, Brittany, Lacoste, Jessica, Yeo, May, Hall, David H, Cummins, Carolyn L, Roy, Peter J
Published in PLoS genetics (06.11.2023)
Published in PLoS genetics (06.11.2023)
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Journal Article
Cyprocide selectively kills nematodes via cytochrome P450 bioactivation
Knox, Jessica, Burns, Andrew R., Cooke, Brittany, Cammalleri, Savina R., Kitner, Megan, Ching, Justin, Castelli, Jack M. P., Puumala, Emily, Snider, Jamie, Koury, Emily, Collins, J. B., Geissah, Salma, Dowling, James J., Andersen, Erik C., Stagljar, Igor, Cowen, Leah E., Lautens, Mark, Zasada, Inga, Roy, Peter J.
Published in Nature communications (02.07.2024)
Published in Nature communications (02.07.2024)
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Journal Article
Development of a yeast whole-cell biocatalyst for MHET conversion into terephthalic acid and ethylene glycol
Loll-Krippleber, Raphael, Sajtovich, Victoria A, Ferguson, Michael W, Ho, Brandon, Burns, Andrew R, Payliss, Brandon J, Bellissimo, Joseph, Peters, Sydney, Roy, Peter J, Wyatt, Haley D M, Brown, Grant W
Published in Microbial cell factories (31.12.2022)
Published in Microbial cell factories (31.12.2022)
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Journal Article
The novel nematicide wact-86 interacts with aldicarb to kill nematodes
Burns, Andrew R, Bagg, Rachel, Yeo, May, Luciani, Genna M, Schertzberg, Michael, Fraser, Andy G, Roy, Peter J
Published in PLoS neglected tropical diseases (05.04.2017)
Published in PLoS neglected tropical diseases (05.04.2017)
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Journal Article
Author Correction: Caenorhabditis elegans is a useful model for anthelmintic discovery
Burns, Andrew R., Luciani, Genna M., Musso, Gabriel, Bagg, Rachel, Yeo, May, Zhang, Yuqian, Rajendran, Luckshi, Glavin, John, Hunter, Robert, Redman, Elizabeth, Stasiuk, Susan, Schertzberg, Michael, McQuibban, G. Angus, Caffrey, Conor R., Cutler, Sean R., Tyers, Mike, Giaever, Guri, Nislow, Corey, Fraser, Andy G., MacRae, Calum A., Gilleard, John, Roy, Peter J.
Published in Nature communications (24.07.2020)
Published in Nature communications (24.07.2020)
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Journal Article
A predictive model for drug bioaccumulation and bioactivity in Caenorhabditis elegans
Burns, Andrew R, Wallace, Iain M, Wildenhain, Jan, Tyers, Mike, Giaever, Guri, Bader, Gary D, Nislow, Corey, Cutler, Sean R, Roy, Peter J
Published in Nature chemical biology (30.05.2010)
Published in Nature chemical biology (30.05.2010)
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Journal Article
Egg-laying and locomotory screens with C. elegans yield a nematode-selective small molecule stimulator of neurotransmitter release
Harrington, Sean, Knox, Jessica J., Burns, Andrew R., Choo, Ken-Loon, Au, Aaron, Kitner, Megan, Haeberli, Cecile, Pyche, Jacob, D’Amata, Cassandra, Kim, Yong-Hyun, Volpatti, Jonathan R., Guiliani, Maximillano, Snider, Jamie, Wong, Victoria, Palmeira, Bruna M., Redman, Elizabeth M., Vaidya, Aditya S., Gilleard, John S., Stagljar, Igor, Cutler, Sean R., Kulke, Daniel, Dowling, James J., Yip, Christopher M., Keiser, Jennifer, Zasada, Inga, Lautens, Mark, Roy, Peter J.
Published in Communications biology (24.08.2022)
Published in Communications biology (24.08.2022)
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Journal Article
Caenorhabditis elegans is a useful model for anthelmintic discovery
Burns, Andrew R., Luciani, Genna M., Musso, Gabriel, Bagg, Rachel, Yeo, May, Zhang, Yuqian, Rajendran, Luckshika, Glavin, John, Hunter, Robert, Redman, Elizabeth, Stasiuk, Susan, Schertzberg, Michael, Angus McQuibban, G., Caffrey, Conor R., Cutler, Sean R., Tyers, Mike, Giaever, Guri, Nislow, Corey, Fraser, Andy G., MacRae, Calum A., Gilleard, John, Roy, Peter J.
Published in Nature communications (25.06.2015)
Published in Nature communications (25.06.2015)
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Journal Article
A predictive model for drug bioaccumulation and bioactivity in Caenorhabditis elegans
Roy, Peter J, Burns, Andrew R, Wallace, Iain M, Wildenhain, Jan, Tyers, Mike, Giaever, Guri, Bader, Gary D, Nislow, Corey, Cutler, Sean R
Published in Nature chemical biology (01.07.2010)
Published in Nature chemical biology (01.07.2010)
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Journal Article
Selective control of parasitic nematodes using bioactivated nematicides
Burns, Andrew R., Baker, Rachel J., Kitner, Megan, Knox, Jessica, Cooke, Brittany, Volpatti, Jonathan R., Vaidya, Aditya S., Puumala, Emily, Palmeira, Bruna M., Redman, Elizabeth M., Snider, Jamie, Marwah, Sagar, Chung, Sai W., MacDonald, Margaret H., Tiefenbach, Jens, Hu, Chun, Xiao, Qi, Finney, Constance A. M., Krause, Henry M., MacParland, Sonya A., Stagljar, Igor, Gilleard, John S., Cowen, Leah E., Meyer, Susan L. F., Cutler, Sean R., Dowling, James J., Lautens, Mark, Zasada, Inga, Roy, Peter J.
Published in Nature (London) (01.06.2023)
Published in Nature (London) (01.06.2023)
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Journal Article
Two components of actin-based retrograde flow in sea urchin coelomocytes
Henson, J H, Svitkina, T M, Burns, A R, Hughes, H E, MacPartland, K J, Nazarian, R, Borisy, G G
Published in Molecular biology of the cell (01.12.1999)
Published in Molecular biology of the cell (01.12.1999)
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Journal Article
High-throughput screening of small molecules for bioactivity and target identification in Caenorhabditis elegans
Roy, Peter J, Burns, Andrew R, Kwok, Trevor C Y, Howard, Al, Houston, Ed, Johanson, Karl, Chan, Anthony, Cutler, Sean R, McCourt, Peter
Published in Nature protocols (01.11.2006)
Published in Nature protocols (01.11.2006)
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Journal Article
Wound closure in the lamellipodia of single cells: mediation by actin polymerization in the absence of an actomyosin purse string
Henson, John H, Nazarian, Ronniel, Schulberg, Katrina L, Trabosh, Valerie A, Kolnik, Sarah E, Burns, Andrew R, McPartland, Kenneth J
Published in Molecular biology of the cell (01.03.2002)
Published in Molecular biology of the cell (01.03.2002)
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Journal Article
Author Correction: Caenorhabditiselegans is a useful model for anthelmintic discovery
Burns, Andrew R., Luciani, Genna M., Musso, Gabriel, Bagg, Rachel, Yeo, May, Zhang, Yuqian, Rajendran, Luckshi, Glavin, John, Hunter, Robert, Redman, Elizabeth, Stasiuk, Susan, Schertzberg, Michael, McQuibban, G. Angus, Caffrey, Conor R., Cutler, Sean R., Tyers, Mike, Giaever, Guri, Nislow, Corey, Fraser, Andy G., MacRae, Calum A., Gilleard, John, Roy, Peter J.
Published in Nature communications (24.07.2020)
Published in Nature communications (24.07.2020)
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Journal Article
Compound Prioritization Methods Increase Rates of Chemical Probe Discovery in Model Organisms
Wallace, Iain M., Urbanus, Malene L., Luciani, Genna M., Burns, Andrew R., Han, Mitchell K.L., Wang, Hao, Arora, Kriti, Heisler, Lawrence E., Proctor, Michael, St. Onge, Robert P., Roemer, Terry, Roy, Peter J., Cummins, Carolyn L., Bader, Gary D., Nislow, Corey, Giaever, Guri
Published in Chemistry & biology (28.10.2011)
Published in Chemistry & biology (28.10.2011)
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Journal Article
Parasitic nematodes activate chemicals that can kill them
Published in Nature (London)
(24.05.2023)
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Journal Article