Cytotoxicity of paclitaxel in breast cancer is due to chromosome missegregation on multipolar spindles
Zasadil, Lauren M, Andersen, Kristen A, Yeum, Dabin, Rocque, Gabrielle B, Wilke, Lee G, Tevaarwerk, Amye J, Raines, Ronald T, Burkard, Mark E, Weaver, Beth A
Published in Science translational medicine (26.03.2014)
Published in Science translational medicine (26.03.2014)
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Patient-Derived Cancer Organoid Cultures to Predict Sensitivity to Chemotherapy and Radiation
Pasch, Cheri A, Favreau, Peter F, Yueh, Alexander E, Babiarz, Christopher P, Gillette, Amani A, Sharick, Joe T, Karim, Mohammad Rezaul, Nickel, Kwangok P, DeZeeuw, Alyssa K, Sprackling, Carley M, Emmerich, Philip B, DeStefanis, Rebecca A, Pitera, Rosabella T, Payne, Susan N, Korkos, Demetra P, Clipson, Linda, Walsh, Christine M, Miller, Devon, Carchman, Evie H, Burkard, Mark E, Lemmon, Kayla K, Matkowskyj, Kristina A, Newton, Michael A, Ong, Irene M, Bassetti, Michael F, Kimple, Randall J, Skala, Melissa C, Deming, Dustin A
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Published in Clinical cancer research (01.09.2019)
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Anillin Phosphorylation Controls Timely Membrane Association and Successful Cytokinesis
Kim, Hyunjung, Johnson, James M, Lera, Robert F, Brahma, Sarang, Burkard, Mark E
Published in PLoS genetics (12.01.2017)
Published in PLoS genetics (12.01.2017)
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Plk1 self-organization and priming phosphorylation of HsCYK-4 at the spindle midzone regulate the onset of division in human cells
Burkard, Mark E, Maciejowski, John, Rodriguez-Bravo, Verónica, Repka, Michael, Lowery, Drew M, Clauser, Karl R, Zhang, Chao, Shokat, Kevan M, Carr, Steven A, Yaffe, Michael B, Jallepalli, Prasad V
Published in PLoS biology (26.05.2009)
Published in PLoS biology (26.05.2009)
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E2112: Randomized Phase III Trial of Endocrine Therapy Plus Entinostat or Placebo in Hormone Receptor-Positive Advanced Breast Cancer. A Trial of the ECOG-ACRIN Cancer Research Group
Connolly, Roisin M, Zhao, Fengmin, Miller, Kathy D, Lee, Min-Jung, Piekarz, Richard L, Smith, Karen L, Brown-Glaberman, Ursa A, Winn, Jennifer S, Faller, Bryan A, Onitilo, Adedayo A, Burkard, Mark E, Budd, George T, Levine, Ellis G, Royce, Melanie E, Kaufman, Peter A, Thomas, Alexandra, Trepel, Jane B, Wolff, Antonio C, Sparano, Joseph A
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Published in Journal of clinical oncology (01.10.2021)
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CHARTS: a web application for characterizing and comparing tumor subpopulations in publicly available single-cell RNA-seq data sets
Bernstein, Matthew N, Ni, Zijian, Collins, Michael, Burkard, Mark E, Kendziorski, Christina, Stewart, Ron
Published in BMC bioinformatics (23.02.2021)
Published in BMC bioinformatics (23.02.2021)
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Centrosome amplification induces high grade features and is prognostic of worse outcomes in breast cancer
Denu, Ryan A, Zasadil, Lauren M, Kanugh, Craig, Laffin, Jennifer, Weaver, Beth A, Burkard, Mark E
Published in BMC cancer (29.01.2016)
Published in BMC cancer (29.01.2016)
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CENP-E Inhibition Induces Chromosomal Instability and Synergizes with Diverse Microtubule-Targeting Agents in Breast Cancer
Tucker, John B, Carlsen, Caleb L, Scribano, Christina M, Pattaswamy, Srishrika M, Burkard, Mark E, Weaver, Beth A
Published in Cancer research (Chicago, Ill.) (15.08.2024)
Published in Cancer research (Chicago, Ill.) (15.08.2024)
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Chromosomal instability sensitizes patient breast tumors to multipolar divisions induced by paclitaxel
Scribano, Christina M, Wan, Jun, Esbona, Karla, Tucker, John B, Lasek, Amber, Zhou, Amber S, Zasadil, Lauren M, Molini, Ryan, Fitzgerald, Jonathan, Lager, Angela M, Laffin, Jennifer J, Correia-Staudt, Kayla, Wisinski, Kari B, Tevaarwerk, Amye J, O'Regan, Ruth, McGregor, Stephanie M, Fowler, Amy M, Chappell, Richard J, Bugni, Tim S, Burkard, Mark E, Weaver, Beth A
Published in Science translational medicine (08.09.2021)
Published in Science translational medicine (08.09.2021)
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A survey of chromosomal instability measures across mechanistic models
Lynch, Andrew R, Bradford, Shermineh, Zhou, Amber S, Oxendine, Kim, Henderson, Les, Horner, Vanessa L, Weaver, Beth A, Burkard, Mark E
Published in Proceedings of the National Academy of Sciences - PNAS (16.04.2024)
Published in Proceedings of the National Academy of Sciences - PNAS (16.04.2024)
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Diverse microtubule-targeted anticancer agents kill cells by inducing chromosome missegregation on multipolar spindles
Zhou, Amber S, Tucker, John B, Scribano, Christina M, Lynch, Andrew R, Carlsen, Caleb L, Pop-Vicas, Sophia T, Pattaswamy, Srishrika M, Burkard, Mark E, Weaver, Beth A
Published in PLoS biology (26.10.2023)
Published in PLoS biology (26.10.2023)
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High nuclear TPX2 expression correlates with TP53 mutation and poor clinical behavior in a large breast cancer cohort, but is not an independent predictor of chromosomal instability
Matson, Daniel R, Denu, Ryan A, Zasadil, Lauren M, Burkard, Mark E, Weaver, Beth A, Flynn, Christopher, Stukenberg, P Todd
Published in BMC cancer (23.02.2021)
Published in BMC cancer (23.02.2021)
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Metabolic Heterogeneity in Patient Tumor-Derived Organoids by Primary Site and Drug Treatment
Sharick, Joe T., Walsh, Christine M., Sprackling, Carley M., Pasch, Cheri A., Pham, Dan L., Esbona, Karla, Choudhary, Alka, Garcia-Valera, Rebeca, Burkard, Mark E., McGregor, Stephanie M., Matkowskyj, Kristina A., Parikh, Alexander A., Meszoely, Ingrid M., Kelley, Mark C., Tsai, Susan, Deming, Dustin A., Skala, Melissa C.
Published in Frontiers in oncology (15.05.2020)
Published in Frontiers in oncology (15.05.2020)
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Polo-like kinase 4 maintains centriolar satellite integrity by phosphorylation of centrosomal protein 131 (CEP131)
Denu, Ryan A., Sass, Madilyn M., Johnson, James M., Potts, Gregory K., Choudhary, Alka, Coon, Joshua J., Burkard, Mark E.
Published in The Journal of biological chemistry (19.04.2019)
Published in The Journal of biological chemistry (19.04.2019)
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