Expression of organic cation transporters OCT1 (SLC22A1) and OCT3 (SLC22A3) is affected by genetic factors and cholestasis in human liver
Nies, Anne T., Koepsell, Hermann, Winter, Stefan, Burk, Oliver, Klein, Kathrin, Kerb, Reinhold, Zanger, Ulrich M., Keppler, Dietrich, Schwab, Matthias, Schaeffeler, Elke
Published in Hepatology (Baltimore, Md.) (01.10.2009)
Published in Hepatology (Baltimore, Md.) (01.10.2009)
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Journal Article
Nuclear Receptor Response Elements Mediate Induction of Intestinal MDR1 by Rifampin
Geick, Anke, Eichelbaum, Michel, Burk, Oliver
Published in The Journal of biological chemistry (04.05.2001)
Published in The Journal of biological chemistry (04.05.2001)
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Journal Article
Direct transcriptional regulation of human hepatic cytochrome P450 3A4 (CYP3A4) by peroxisome proliferator-activated receptor alpha (PPARα)
Thomas, Maria, Burk, Oliver, Klumpp, Britta, Kandel, Benjamin A, Damm, Georg, Weiss, Thomas S, Klein, Kathrin, Schwab, Matthias, Zanger, Ulrich M
Published in Molecular pharmacology (01.03.2013)
Published in Molecular pharmacology (01.03.2013)
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Journal Article
Development and Experimental Validation of Regularized Machine Learning Models Detecting New, Structurally Distinct Activators of PXR
Hirte, Steffen, Burk, Oliver, Tahir, Ammar, Schwab, Matthias, Windshügel, Björn, Kirchmair, Johannes
Published in Cells (Basel, Switzerland) (07.04.2022)
Published in Cells (Basel, Switzerland) (07.04.2022)
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Journal Article
Discrepancy in interactions and conformational dynamics of pregnane X receptor (PXR) bound to an agonist and a novel competitive antagonist
Rashidian, Azam, Mustonen, Enni-Kaisa, Kronenberger, Thales, Schwab, Matthias, Burk, Oliver, Laufer, Stefan A., Pantsar, Tatu
Published in Computational and structural biotechnology journal (01.01.2022)
Published in Computational and structural biotechnology journal (01.01.2022)
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Journal Article
Target Hopping from Protein Kinases to PXR: Identification of Small-Molecule Protein Kinase Inhibitors as Selective Modulators of Pregnane X Receptor from TüKIC Library
Mustonen, Enni-Kaisa, Pantsar, Tatu, Rashidian, Azam, Reiner, Juliander, Schwab, Matthias, Laufer, Stefan, Burk, Oliver
Published in Cells (Basel, Switzerland) (12.04.2022)
Published in Cells (Basel, Switzerland) (12.04.2022)
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Journal Article
Cytochrome P450 3A4 and P-glycoprotein expression in human small intestinal enterocytes and hepatocytes: a comparative analysis in paired tissue specimens
von Richter, Oliver, Burk, Oliver, Fromm, Martin F, Thon, Klaus P, Eichelbaum, Michel, Kivistö, Kari T
Published in Clinical pharmacology and therapeutics (01.03.2004)
Published in Clinical pharmacology and therapeutics (01.03.2004)
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Journal Article
Antimalarial Artemisinin Drugs Induce Cytochrome P450 and MDR1 Expression by Activation of Xenosensors Pregnane X Receptor and Constitutive Androstane Receptor
Burk, Oliver, Arnold, Katja A, Nussler, Andreas K, Schaeffeler, Elke, Efimova, Ekaterina, Avery, Bonnie A, Avery, Mitchell A, Fromm, Martin F, Eichelbaum, Michel
Published in Molecular pharmacology (01.06.2005)
Published in Molecular pharmacology (01.06.2005)
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Journal Article
The Induction of Cytochrome P450 3A5 (CYP3A5) in the Human Liver and Intestine Is Mediated by the Xenobiotic Sensors Pregnane X Receptor (PXR) and Constitutively Activated Receptor (CAR)
Burk, Oliver, Koch, Ina, Raucy, Judy, Hustert, Elisabeth, Eichelbaum, Michel, Brockmöller, Jürgen, Zanger, Ulrich M., Wojnowski, Leszek
Published in The Journal of biological chemistry (10.09.2004)
Published in The Journal of biological chemistry (10.09.2004)
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Journal Article
Human Sterol Regulatory Element-Binding Protein 1a Contributes Significantly to Hepatic Lipogenic Gene Expression
Bitter, Andreas, Nüssler, Andreas K., Thasler, Wolfgang E., Klein, Kathrin, Zanger, Ulrich M., Schwab, Matthias, Burk, Oliver
Published in Cellular physiology and biochemistry (01.01.2015)
Published in Cellular physiology and biochemistry (01.01.2015)
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Journal Article
Correction: Structural and Functional Similarity of Amphibian Constitutive Androstane Receptor with Mammalian Pregnane X Receptor
Mathäs, Marianne, Nusshag, Christian, Burk, Oliver, Gödtel-Armbrust, Ute, Herlyn, Holger, Wojnowski, Leszek, Windshügel, Björn
Published in PloS one (01.02.2016)
Published in PloS one (01.02.2016)
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Journal Article
A role for constitutive androstane receptor in the regulation of human intestinal MDR1 expression
Burk, Oliver, Arnold, Katja A., Geick, Anke, Tegude, Heike, Eichelbaum, Michel
Published in Biological chemistry (01.06.2005)
Published in Biological chemistry (01.06.2005)
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Journal Article
Interindividual Variability and Tissue-Specificity in the Expression of Cytochrome P450 3A mRNA
KOCH, Ina, WEIL, Regina, WOJNOWSKI, Leszek, WOLBOLD, Renzo, BROCKMÖLLER, Jürgen, HUSTERT, Elisabeth, BURK, Oliver, NUESSLER, Andreas, NEUHAUS, Peter, EICHELBAUM, Michel, ZANGER, Ulrich
Published in Drug metabolism and disposition (01.10.2002)
Published in Drug metabolism and disposition (01.10.2002)
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Journal Article
Evolutionary History and Functional Characterization of the Amphibian Xenosensor CAR
Mathäs, Marianne, Burk, Oliver, Qiu, Huan, Nußhag, Christian, Gödtel-Armbrust, Ute, Baranyai, Dorothea, Deng, Shiwei, Römer, Kristin, Nem, Dieudonné, Windshügel, Björn, Wojnowski, Leszek
Published in Molecular endocrinology (Baltimore, Md.) (01.01.2012)
Published in Molecular endocrinology (Baltimore, Md.) (01.01.2012)
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Journal Article
Structural and functional similarity of amphibian constitutive androstane receptor with mammalian pregnane X receptor
Mathäs, Marianne, Nusshag, Christian, Nuβhag, Christian, Burk, Oliver, Gödtel-Armbrust, Ute, Herlyn, Holger, Wojnowski, Leszek, Windshügel, Björn
Published in PloS one (05.05.2014)
Published in PloS one (05.05.2014)
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Journal Article
Natural Protein Variants of Pregnane X Receptor with Altered Transactivation Activity Toward CYP3A4
HUSTERT, Elisabeth, ZIBAT, Arne, BURK, Oliver, PRESECAN-SIEDEL, Elena, EISELT, Regina, MUELLER, Romy, FUSS, Christine, BREHM, Ilka, BRINKMANN, Ulrich, EICHELBAUM, Michel, WOJNOWSKI, Leszek
Published in Drug metabolism and disposition (01.11.2001)
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Published in Drug metabolism and disposition (01.11.2001)
Journal Article
The Effect of Rifampin Treatment on Intestinal Expression of Human MRP Transporters
Fromm, Martin F., Kauffmann, Hans-Martin, Fritz, Peter, Burk, Oliver, Kroemer, Heyo K., Warzok, Rolf W., Eichelbaum, Michel, Siegmund, Werner, Schrenk, Dieter
Published in The American journal of pathology (01.11.2000)
Published in The American journal of pathology (01.11.2000)
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Journal Article
Molecular Mechanisms of Polymorphic CYP3A7 Expression in Adult Human Liver and Intestine
Burk, Oliver, Tegude, Heike, Koch, Ina, Hustert, Elisabeth, Wolbold, Renzo, Glaeser, Hartmut, Klein, Kathrin, Fromm, Martin F., Nuessler, Andreas K., Neuhaus, Peter, Zanger, Ulrich M., Eichelbaum, Michel, Wojnowski, Leszek
Published in The Journal of biological chemistry (05.07.2002)
Published in The Journal of biological chemistry (05.07.2002)
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Journal Article
PXR Variants and Artemisinin Use in Vietnamese Subjects: Frequency Distribution and Impact on the Interindividual Variability of CYP3A Induction by Artemisinin
PIEDADE, Rita, SCHAEFFELER, Elke, WINTER, Stefan, ASIMUS, Sara, SCHWAB, Matthias, ASHTON, Michael, BURK, Oliver, GIL, José P
Published in Antimicrobial Agents and Chemotherapy (01.04.2012)
Published in Antimicrobial Agents and Chemotherapy (01.04.2012)
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Journal Article