Search Results - "Burger, Pieter B." :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Mechanistic Insight into NMDA Receptor Dysregulation by Rare Variants in the GluN2A and GluN2B Agonist Binding Domains

Mechanistic Insight into NMDA Receptor Dysregulation by Rare Variants in the GluN2A and GluN2B Agonist Binding Domains

by Swanger, Sharon A., Chen, Wenjuan, Wells, Gordon, Burger, Pieter B., Tankovic, Anel, Bhattacharya, Subhrajit, Strong, Katie L., Hu, Chun, Kusumoto, Hirofumi, Zhang, Jing, Adams, David R., Millichap, John J., Petrovski, Slavé, Traynelis, Stephen F., Yuan, Hongjie
Published in American journal of human genetics (01.12.2016)

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Error Tolerance of Machine Learning Algorithms across Contemporary Biological Targets

Error Tolerance of Machine Learning Algorithms across Contemporary Biological Targets

by Kaiser, Thomas M, Burger, Pieter B
Published in Molecules (Basel, Switzerland) (04.06.2019)

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Mechanism for noncompetitive inhibition by novel GluN2C/D N-methyl-D-aspartate receptor subunit-selective modulators

Mechanism for noncompetitive inhibition by novel GluN2C/D N-methyl-D-aspartate receptor subunit-selective modulators

by Acker, Timothy M, Yuan, Hongjie, Hansen, Kasper B, Vance, Katie M, Ogden, Kevin K, Jensen, Henrik S, Burger, Pieter B, Mullasseril, Praseeda, Snyder, James P, Liotta, Dennis C, Traynelis, Stephen F
Published in Molecular pharmacology (01.11.2011)

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Exploring inhibition of Pdx1, a component of the PLP synthase complex of the human malaria parasite Plasmodium falciparum

Exploring inhibition of Pdx1, a component of the PLP synthase complex of the human malaria parasite Plasmodium falciparum

by Reeksting, Shaun B, Müller, Ingrid B, Burger, Pieter B, Burgos, Emmanuel S, Salmon, Laurent, Louw, Abraham I, Birkholtz, Lyn-Marie, Wrenger, Carsten
Published in Biochemical journal (01.01.2013)

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A novel inhibitor of Plasmodium falciparum spermidine synthase: a twist in the tail

A novel inhibitor of Plasmodium falciparum spermidine synthase: a twist in the tail

by Burger, Pieter B, Williams, Marni, Sprenger, Janina, Reeksting, Shaun B, Botha, Mariëtte, Müller, Ingrid B, Joubert, Fourie, Birkholtz, Lyn-Marie, Louw, Abraham I
Published in Malaria journal (05.02.2015)

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$Functional Evaluation of a De Novo GRIN2A Mutation Identified in a Patient with Profound Global Developmental Delay and Refractory Epilepsy$

Functional Evaluation of a De Novo GRIN2A Mutation Identified in a Patient with Profound Global Developmental Delay and Refractory Epilepsy

by Chen, Wenjuan, Tankovic, Anel, Burger, Pieter B, Kusumoto, Hirofumi, Traynelis, Stephen F, Yuan, Hongjie
Published in Molecular pharmacology (01.04.2017)

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FEP Augmentation as a Means to Solve Data Paucity Problems for Machine Learning in Chemical Biology

FEP Augmentation as a Means to Solve Data Paucity Problems for Machine Learning in Chemical Biology

by Burger, Pieter B., Hu, Xiaohu, Balabin, Ilya, Muller, Morné, Stanley, Megan, Joubert, Fourie, Kaiser, Thomas M.
Published in Journal of chemical information and modeling (13.05.2024)

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NMDA receptor channel gating control by the pre-M1 helix

NMDA receptor channel gating control by the pre-M1 helix

by McDaniel, Miranda J, Ogden, Kevin K, Kell, Steven A, Burger, Pieter B, Liotta, Dennis C, Traynelis, Stephen F
Published in The Journal of general physiology (06.04.2020)

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Negative allosteric modulation of GluN1/GluN3 NMDA receptors

Negative allosteric modulation of GluN1/GluN3 NMDA receptors

by Zhu, Zongjian, Yi, Feng, Epplin, Matthew P., Liu, Ding, Summer, Samantha L., Mizu, Ruth, Shaulsky, Gil, XiangWei, Wenshu, Tang, Weiting, Burger, Pieter B., Menaldino, David S., Myers, Scott J., Liotta, Dennis C., Hansen, Kasper B., Yuan, Hongjie, Traynelis, Stephen F.
Published in Neuropharmacology (01.10.2020)

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Structural determinants and mechanism of action of a GluN2C-selective NMDA receptor positive allosteric modulator

Structural determinants and mechanism of action of a GluN2C-selective NMDA receptor positive allosteric modulator

by Khatri, Alpa, Burger, Pieter B, Swanger, Sharon A, Hansen, Kasper B, Zimmerman, Sommer, Karakas, Erkan, Liotta, Dennis C, Furukawa, Hiro, Snyder, James P, Traynelis, Stephen F
Published in Molecular pharmacology (01.11.2014)

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A Machine Learning Approach for Predicting HIV Reverse Transcriptase Mutation Susceptibility of Biologically Active Compounds

A Machine Learning Approach for Predicting HIV Reverse Transcriptase Mutation Susceptibility of Biologically Active Compounds

by Kaiser, Thomas M, Burger, Pieter B, Butch, Christopher J, Pelly, Stephen C, Liotta, Dennis C
Published in Journal of chemical information and modeling (27.08.2018)

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Structural Determinants of D-Cycloserine Efficacy at the NR1/NR2C NMDA Receptors

Structural Determinants of D-Cycloserine Efficacy at the NR1/NR2C NMDA Receptors

by Dravid, Shashank M, Burger, Pieter B, Prakash, Anand, Geballe, Matthew T, Yadav, Roopali, Le, Phuong, Vellano, Kimberly, Snyder, James P, Traynelis, Stephen F
Published in The Journal of neuroscience (17.02.2010)

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The Bioactive Protein-Ligand Conformation of GluN2C-Selective Positive Allosteric Modulators Bound to the NMDA Receptor

The Bioactive Protein-Ligand Conformation of GluN2C-Selective Positive Allosteric Modulators Bound to the NMDA Receptor

by Kaiser, Thomas M, Kell, Steven A, Kusumoto, Hirofumi, Shaulsky, Gil, Bhattacharya, Subhrajit, Epplin, Matthew P, Strong, Katie L, Miller, Eric J, Cox, Bryan D, Menaldino, David S, Liotta, Dennis C, Traynelis, Stephen F, Burger, Pieter B
Published in Molecular pharmacology (01.02.2018)

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Selective targeting of CD38 hydrolase and cyclase activity as an approach to immunostimulation

Selective targeting of CD38 hydrolase and cyclase activity as an approach to immunostimulation

by Benton, Thomas Z, Mills, Catherine M, Turner, Jonathan M, Francis, Megan J, Solomon, Dalan J, Burger, Pieter B, Peterson, Yuri K, Dolloff, Nathan G, Bachmann, André S, Woster, Patrick M
Published in RSC advances (11.10.2021)

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The Structure–Activity Relationship of a Tetrahydroisoquinoline Class of N‑Methyl‑d‑Aspartate Receptor Modulators that Potentiates GluN2B-Containing N‑Methyl‑d‑Aspartate Receptors

The Structure–Activity Relationship of a Tetrahydroisoquinoline Class of N‑Methyl‑d‑Aspartate Receptor Modulators that Potentiates GluN2B-Containing N‑Methyl‑d‑Aspartate Receptors

by Strong, Katie L, Epplin, Matthew P, Bacsa, John, Butch, Christopher J, Burger, Pieter B, Menaldino, David S, Traynelis, Stephen F, Liotta, Dennis C
Published in Journal of medicinal chemistry (13.07.2017)

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Mapping the binding of GluN2B-selective N-methyl-D-aspartate receptor negative allosteric modulators

Mapping the binding of GluN2B-selective N-methyl-D-aspartate receptor negative allosteric modulators

by Burger, Pieter B, Yuan, Hongjie, Karakas, Erkan, Geballe, Matthew, Furukawa, Hiro, Liotta, Dennis C, Snyder, James P, Traynelis, Stephen F
Published in Molecular pharmacology (01.08.2012)

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Distinct GluN1 and GluN2 Structural Determinants for Subunit-Selective Positive Allosteric Modulation of N -Methyl-d-aspartate Receptors

Distinct GluN1 and GluN2 Structural Determinants for Subunit-Selective Positive Allosteric Modulation of N -Methyl-d-aspartate Receptors

by Strong, Katie L, Epplin, Matthew P, Ogden, Kevin K, Burger, Pieter B, Kaiser, Thomas M, Wilding, Timothy J, Kusumoto, Hiro, Camp, Chad R, Shaulsky, Gil, Bhattacharya, Subhrajit, Perszyk, Riley E, Menaldino, David S, McDaniel, Miranda J, Zhang, Jing, Le, Phuong, Banke, Tue G, Hansen, Kasper B, Huettner, James E, Liotta, Dennis C, Traynelis, Stephen F
Published in ACS chemical neuroscience (06.01.2021)

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Accelerated Discovery of Potent Fusion Inhibitors for Respiratory Syncytial Virus

Accelerated Discovery of Potent Fusion Inhibitors for Respiratory Syncytial Virus

by Pribut, Nicole, Kaiser, Thomas M, Wilson, Robert J, Jecs, Edgars, Dentmon, Zackery W, Pelly, Stephen C, Sharma, Savita, Bartsch, Perry W, Burger, Pieter B, Hwang, Soyon S, Le, Thalia, Sourimant, Julien, Yoon, Jeong-Joong, Plemper, Richard K, Liotta, Dennis C
Published in ACS infectious diseases (08.05.2020)

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Discovery-2: an interactive resource for the rational selection and comparison of putative drug target proteins in malaria

Discovery-2: an interactive resource for the rational selection and comparison of putative drug target proteins in malaria

by Mpangase, Phelelani T, Szolkiewicz, Michal J, le Grange, Misha, Smit, Jeanré H, Burger, Pieter B, Joubert, Fourie
Published in Malaria journal (28.03.2013)

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Structural and mechanistic insights into the action of Plasmodium falciparum spermidine synthase

Structural and mechanistic insights into the action of Plasmodium falciparum spermidine synthase

by Burger, Pieter B., Birkholtz, Lyn-Marie, Joubert, Fourie, Haider, Nashya, Walter, Rolf D., Louw, Abraham I.
Published in Bioorganic & medicinal chemistry (15.02.2007)

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