Fatty acid uptake and lipid storage induced by HIF-1α contribute to cell growth and survival after hypoxia-reoxygenation
Bensaad, Karim, Favaro, Elena, Lewis, Caroline A, Peck, Barrie, Lord, Simon, Collins, Jennifer M, Pinnick, Katherine E, Wigfield, Simon, Buffa, Francesca M, Li, Ji-Liang, Zhang, Qifeng, Wakelam, Michael J O, Karpe, Fredrik, Schulze, Almut, Harris, Adrian L
Published in Cell reports (Cambridge) (09.10.2014)
Published in Cell reports (Cambridge) (09.10.2014)
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Glucose Utilization via Glycogen Phosphorylase Sustains Proliferation and Prevents Premature Senescence in Cancer Cells
Favaro, Elena, Bensaad, Karim, Chong, Mei G., Tennant, Daniel A., Ferguson, David J.P., Snell, Cameron, Steers, Graham, Turley, Helen, Li, Ji-Liang, Günther, Ulrich L., Buffa, Francesca M., McIntyre, Alan, Harris, Adrian L.
Published in Cell metabolism (05.12.2012)
Published in Cell metabolism (05.12.2012)
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FANCD2 limits replication stress and genome instability in cells lacking BRCA2
Michl, Johanna, Zimmer, Jutta, Buffa, Francesca M, McDermott, Ultan, Tarsounas, Madalena
Published in Nature structural & molecular biology (01.08.2016)
Published in Nature structural & molecular biology (01.08.2016)
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A Core Human Primary Tumor Angiogenesis Signature Identifies the Endothelial Orphan Receptor ELTD1 as a Key Regulator of Angiogenesis
Masiero, Massimo, Simões, Filipa Costa, Han, Hee Dong, Snell, Cameron, Peterkin, Tessa, Bridges, Esther, Mangala, Lingegowda S., Wu, Sherry Yen-Yao, Pradeep, Sunila, Li, Demin, Han, Cheng, Dalton, Heather, Lopez-Berestein, Gabriel, Tuynman, Jurriaan B., Mortensen, Neil, Li, Ji-Liang, Patient, Roger, Sood, Anil K., Banham, Alison H., Harris, Adrian L., Buffa, Francesca M.
Published in Cancer cell (12.08.2013)
Published in Cancer cell (12.08.2013)
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Replication catastrophe induced by cyclic hypoxia leads to increased APOBEC3B activity
Bader, Samuel B, Ma, Tiffany S, Simpson, Charlotte J, Liang, Jiachen, Maezono, Sakura Eri B, Olcina, Monica M, Buffa, Francesca M, Hammond, Ester M
Published in Nucleic acids research (21.07.2021)
Published in Nucleic acids research (21.07.2021)
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The anti-malarial atovaquone increases radiosensitivity by alleviating tumour hypoxia
Ashton, Thomas M., Fokas, Emmanouil, Kunz-Schughart, Leoni A., Folkes, Lisa K., Anbalagan, Selvakumar, Huether, Melanie, Kelly, Catherine J., Pirovano, Giacomo, Buffa, Francesca M., Hammond, Ester M., Stratford, Michael, Muschel, Ruth J., Higgins, Geoff S., McKenna, William Gillies
Published in Nature communications (25.07.2016)
Published in Nature communications (25.07.2016)
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Direct targeting of Sec23a by miR-200s influences cancer cell secretome and promotes metastatic colonization
Korpal, Manav, Ell, Brian J, Buffa, Francesca M, Ibrahim, Toni, Blanco, Mario A, Celià-Terrassa, Toni, Mercatali, Laura, Khan, Zia, Goodarzi, Hani, Hua, Yuling, Wei, Yong, Hu, Guohong, Garcia, Benjamin A, Ragoussis, Jiannis, Amadori, Dino, Harris, Adrian L, Kang, Yibin
Published in Nature medicine (01.09.2011)
Published in Nature medicine (01.09.2011)
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microRNA-Associated Progression Pathways and Potential Therapeutic Targets Identified by Integrated mRNA and microRNA Expression Profiling in Breast Cancer
BUFFA, Francesca M, CAMPS, Carme, WINCHESTER, Laura, SNELL, Cameron E, GEE, Harriet E, SHELDON, Helen, TAYLOR, Marian, HARRIS, Adrian L, RAGOUSSIS, Jiannis
Published in Cancer research (Chicago, Ill.) (01.09.2011)
Published in Cancer research (Chicago, Ill.) (01.09.2011)
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miR-182-Mediated Downregulation of BRCA1 Impacts DNA Repair and Sensitivity to PARP Inhibitors
Moskwa, Patryk, Buffa, Francesca M., Pan, Yunfeng, Panchakshari, Rohit, Gottipati, Ponnari, Muschel, Ruth J., Beech, John, Kulshrestha, Ritu, Abdelmohsen, Kotb, Weinstock, David M., Gorospe, Myriam, Harris, Adrian L., Helleday, Thomas, Chowdhury, Dipanjan
Published in Molecular cell (21.01.2011)
Published in Molecular cell (21.01.2011)
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hsa-miR-210 Is Induced by Hypoxia and Is an Independent Prognostic Factor in Breast Cancer
CAMPS, Carme, BUFFA, Francesca M, COLELLA, Stefano, MOORE, John, SOTIRIOU, Christos, SHELDON, Helen, HARRIS, Adrian L, GLEADLE, Jonathan M, RAGOUSSIS, Jiannis
Published in Clinical cancer research (01.03.2008)
Published in Clinical cancer research (01.03.2008)
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Robustness and reproducibility for AI learning in biomedical sciences: RENOIR
Barberis, Alessandro, Aerts, Hugo J. W. L., Buffa, Francesca M.
Published in Scientific reports (22.01.2024)
Published in Scientific reports (22.01.2024)
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Estrogen receptor-α directly regulates the hypoxia-inducible factor 1 pathway associated with antiestrogen response in breast cancer
Yang, Jun, AlTahan, Alaa, Jones, Dylan T., Buffa, Francesca M., Bridges, Esther, Interiano, Rodrigo B., Qu, Chunxu, Vogt, Nathan, Li, Ji-Liang, Baban, Dilair, Ragoussis, Jiannis, Nicholson, Robert, Davidoff, Andrew M., Harris, Adrian L.
Published in Proceedings of the National Academy of Sciences - PNAS (08.12.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (08.12.2015)
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hsa‐miR‐210 is a marker of tumor hypoxia and a prognostic factor in head and neck cancer
Gee, Harriet E., Camps, Carme, Buffa, Francesca M., Patiar, Shalini, Winter, Stuart C., Betts, Guy, Homer, Jarrod, Corbridge, Rogan, Cox, Graham, West, Catharine M. L., Ragoussis, Jiannis, Harris, Adrian L.
Published in Cancer (01.05.2010)
Published in Cancer (01.05.2010)
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Hypoxia-induced SETX links replication stress with the unfolded protein response
Ramachandran, Shaliny, Ma, Tiffany S., Griffin, Jon, Ng, Natalie, Foskolou, Iosifina P., Hwang, Ming-Shih, Victori, Pedro, Cheng, Wei-Chen, Buffa, Francesca M., Leszczynska, Katarzyna B., El-Khamisy, Sherif F., Gromak, Natalia, Hammond, Ester M.
Published in Nature communications (17.06.2021)
Published in Nature communications (17.06.2021)
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Metabolic symbiosis between oxygenated and hypoxic tumour cells: An agent-based modelling study
Jayathilake, Pahala Gedara, Victori, Pedro, Pavillet, Clara E, Lee, Chang Heon, Voukantsis, Dimitrios, Miar, Ana, Arora, Anjali, Harris, Adrian L, Morten, Karl J, Buffa, Francesca M
Published in PLoS computational biology (01.03.2024)
Published in PLoS computational biology (01.03.2024)
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Antitumour effect of the mitochondrial complex III inhibitor Atovaquone in combination with anti-PD-L1 therapy in mouse cancer models
Rodriguez-Berriguete, Gonzalo, Puliyadi, Rathi, Machado, Nicole, Barberis, Alessandro, Prevo, Remko, McLaughlin, Martin, Buffa, Francesca M., Harrington, Kevin J., Higgins, Geoff S.
Published in Cell death & disease (11.01.2024)
Published in Cell death & disease (11.01.2024)
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Nutritional Stress Induced by Tryptophan-Degrading Enzymes Results in ATF4-Dependent Reprogramming of the Amino Acid Transporter Profile in Tumor Cells
Timosenko, Elina, Ghadbane, Hemza, Silk, Jonathan D, Shepherd, Dawn, Gileadi, Uzi, Howson, Lauren J, Laynes, Robert, Zhao, Qi, Strausberg, Robert L, Olsen, Lars R, Taylor, Stephen, Buffa, Francesca M, Boyd, Richard, Cerundolo, Vincenzo
Published in Cancer research (Chicago, Ill.) (01.11.2016)
Published in Cancer research (Chicago, Ill.) (01.11.2016)
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New role of fat-free mass in cancer risk linked with genetic predisposition
Harris, Benjamin H. L., Di Giovannantonio, Matteo, Zhang, Ping, Harris, David A., Lord, Simon R., Allen, Naomi E., Maughan, Tim S., Bryant, Richard J., Harris, Adrian L., Bond, Gareth L., Buffa, Francesca M.
Published in Scientific reports (27.03.2024)
Published in Scientific reports (27.03.2024)
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In vitro downregulated hypoxia transcriptome is associated with poor prognosis in breast cancer
Abu-Jamous, Basel, Buffa, Francesca M, Harris, Adrian L, Nandi, Asoke K
Published in Molecular cancer (15.06.2017)
Published in Molecular cancer (15.06.2017)
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