Nrf2-ARE pathway: An emerging target against oxidative stress and neuroinflammation in neurodegenerative diseases
Buendia, Izaskun, Michalska, Patrycja, Navarro, Elisa, Gameiro, Isabel, Egea, Javier, León, Rafael
Published in Pharmacology & therapeutics (Oxford) (01.01.2016)
Published in Pharmacology & therapeutics (Oxford) (01.01.2016)
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Journal Article
Filling the gaps on stroke research: Focus on inflammation and immunity
Levard, Damien, Buendia, Izaskun, Lanquetin, Anastasia, Glavan, Martina, Vivien, Denis, Rubio, Marina
Published in Brain, behavior, and immunity (01.01.2021)
Published in Brain, behavior, and immunity (01.01.2021)
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Journal Article
Anti-inflammatory role of microglial alpha7 nAChRs and its role in neuroprotection
Egea, Javier, Buendia, Izaskun, Parada, Esther, Navarro, Elisa, León, Rafael, Lopez, Manuela G.
Published in Biochemical pharmacology (15.10.2015)
Published in Biochemical pharmacology (15.10.2015)
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Journal Article
The Antioxidant Additive Approach for Alzheimer’s Disease Therapy: New Ferulic (Lipoic) Acid Plus Melatonin Modified Tacrines as Cholinesterases Inhibitors, Direct Antioxidants, and Nuclear Factor (Erythroid-Derived 2)-Like 2 Activators
Benchekroun, Mohamed, Romero, Alejandro, Egea, Javier, León, Rafael, Michalska, Patrycja, Buendía, Izaskun, Jimeno, María Luisa, Jun, Daniel, Janockova, Jana, Sepsova, Vendula, Soukup, Ondrej, Bautista-Aguilera, Oscar M, Refouvelet, Bernard, Ouari, Olivier, Marco-Contelles, José, Ismaili, Lhassane
Published in Journal of medicinal chemistry (10.11.2016)
Published in Journal of medicinal chemistry (10.11.2016)
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Journal Article
Apoε4 disrupts neurovascular regulation and undermines white matter integrity and cognitive function
Koizumi, Kenzo, Hattori, Yorito, Ahn, Sung Ji, Buendia, Izaskun, Ciacciarelli, Antonio, Uekawa, Ken, Wang, Gang, Hiller, Abigail, Zhao, Lingzhi, Voss, Henning U., Paul, Steven M., Schaffer, Chris, Park, Laibaik, Iadecola, Costantino
Published in Nature communications (19.09.2018)
Published in Nature communications (19.09.2018)
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Journal Article
NOX4-dependent neuronal autotoxicity and BBB breakdown explain the superior sensitivity of the brain to ischemic damage
Casas, Ana I., Geuss, Eva, Kleikers, Pamela W. M., Mencl, Stine, Herrmann, Alexander M., Buendia, Izaskun, Egea, Javier, Meuth, Sven G., Lopez, Manuela G., Kleinschnitz, Christoph, Schmidt, Harald H. H. W.
Published in Proceedings of the National Academy of Sciences - PNAS (14.11.2017)
Published in Proceedings of the National Academy of Sciences - PNAS (14.11.2017)
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Journal Article
The microglial α7-acetylcholine nicotinic receptor is a key element in promoting neuroprotection by inducing heme oxygenase-1 via nuclear factor erythroid-2-related factor 2
Parada, Esther, Egea, Javier, Buendia, Izaskun, Negredo, Pilar, Cunha, Ana C, Cardoso, Silvia, Soares, Miguel P, López, Manuela G
Published in Antioxidants & redox signaling (10.10.2013)
Published in Antioxidants & redox signaling (10.10.2013)
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Journal Article
Microglial HO‐1 induction by curcumin provides antioxidant, antineuroinflammatory, and glioprotective effects
Parada, Esther, Buendia, Izaskun, Navarro, Elisa, Avendaño, Carlos, Egea, Javier, López, Manuela G
Published in Molecular nutrition & food research (01.09.2015)
Published in Molecular nutrition & food research (01.09.2015)
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Journal Article
Deficiency in the transcription factor NRF2 worsens inflammatory parameters in a mouse model with combined tauopathy and amyloidopathy
Rojo, Ana I., Pajares, Marta, García-Yagüe, Angel J., Buendia, Izaskun, Van Leuven, Fred, Yamamoto, Masayuki, López, Manuela G., Cuadrado, Antonio
Published in Redox biology (01.09.2018)
Published in Redox biology (01.09.2018)
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Journal Article
Pharmacological doses of melatonin impede cognitive decline in tau‐related Alzheimer models, once tauopathy is initiated, by restoring the autophagic flux
Luengo, Enrique, Buendia, Izaskun, Fernández‐Mendívil, Cristina, Trigo‐Alonso, Paula, Negredo, Pilar, Michalska, Patrycja, Hernández‐García, Borja, Sánchez‐Ramos, Cristina, Bernal, Juan A., Ikezu, Tsuneya, León, Rafael, López, Manuela G.
Published in Journal of pineal research (01.08.2019)
Published in Journal of pineal research (01.08.2019)
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Journal Article
Agmatine, by Improving Neuroplasticity Markers and Inducing Nrf2, Prevents Corticosterone-Induced Depressive-Like Behavior in Mice
Freitas, Andiara E., Egea, Javier, Buendia, Izaskun, Gómez-Rangel, Vanessa, Parada, Esther, Navarro, Elisa, Casas, Ana Isabel, Wojnicz, Aneta, Ortiz, José Avendaño, Cuadrado, Antonio, Ruiz-Nuño, Ana, Rodrigues, Ana Lúcia S., Lopez, Manuela G.
Published in Molecular neurobiology (01.07.2016)
Published in Molecular neurobiology (01.07.2016)
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Journal Article
Alpha7 nicotinic receptor activation protects against oxidative stress via heme-oxygenase I induction
Navarro, Elisa, Buendia, Izaskun, Parada, Esther, León, Rafael, Jansen-Duerr, Pidder, Pircher, Haymo, Egea, Javier, Lopez, Manuela G.
Published in Biochemical pharmacology (15.10.2015)
Published in Biochemical pharmacology (15.10.2015)
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Journal Article
Mitochondrial complex I deactivation is related to superoxide production in acute hypoxia
Hernansanz-Agustín, Pablo, Ramos, Elena, Navarro, Elisa, Parada, Esther, Sánchez-López, Nuria, Peláez-Aguado, Laura, Cabrera-García, J Daniel, Tello, Daniel, Buendia, Izaskun, Marina, Anabel, Egea, Javier, López, Manuela G, Bogdanova, Anna, Martínez-Ruiz, Antonio
Published in Redox biology (01.08.2017)
Published in Redox biology (01.08.2017)
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Journal Article
Novel Multitarget Hybrid Compounds for the Treatment of Alzheimer's Disease
Michalska, Patrycja, Buendia, Izaskun, Del Barrio, Laura, Leon, Rafael
Published in Current topics in medicinal chemistry (01.04.2017)
Published in Current topics in medicinal chemistry (01.04.2017)
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Journal Article
Agmatine Induces Nrf2 and Protects Against Corticosterone Effects in Hippocampal Neuronal Cell Line
Freitas, Andiara E., Egea, Javier, Buendía, Izaskun, Navarro, Elisa, Rada, Patricia, Cuadrado, Antonio, Rodrigues, Ana Lúcia S., López, Manuela G.
Published in Molecular neurobiology (01.06.2015)
Published in Molecular neurobiology (01.06.2015)
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Journal Article
NEDDYLATION HAS A KEY ROLE IN OLIGODENDROCYTE MATURATION AND MYELINATION
Luengas-Escuza, Irene, Bayón-Cordero, Laura, Velasco, Sergio, Varela, Marta, Sánchez-Gómez, María Victoria, Matute, Carlos, Buendia, Izaskun, Woodhoo, Ashwin
Published in IBRO neuroscience reports (01.10.2023)
Published in IBRO neuroscience reports (01.10.2023)
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Journal Article
Antioxidant, Anti-inflammatory and Neuroprotective Profiles of Novel 1,4-Dihydropyridine Derivatives for the Treatment of Alzheimer’s Disease
Michalska, Patrycja, Mayo, Paloma, Fernández-Mendívil, Cristina, Tenti, Giammarco, Duarte, Pablo, Buendia, Izaskun, Ramos, María Teresa, López, Manuela G., Menéndez, J. Carlos, León, Rafael
Published in Antioxidants (01.08.2020)
Published in Antioxidants (01.08.2020)
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Journal Article
MODULATING GABAB RECEPTOR SIGNALING IN OLIGODENDROCYTES AS A THERAPEUTIC STRATEGY IN MULTIPLE SCLEROSIS
Bayón-Cordero, Laura, Ochoa-Bueno, Blanca Isabel, Rubio-López, Esther, Buendia, Izaskun, Bai, Xianshu, Kirchhoff, Frank, Sánchez-Gómez, María Victoria, Matute, Carlos
Published in IBRO neuroscience reports (01.10.2023)
Published in IBRO neuroscience reports (01.10.2023)
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Journal Article
Sensory Input-Dependent Changes in Glutamatergic Neurotransmission- Related Genes and Proteins in the Adult Rat Trigeminal Ganglion
Fernández-Montoya, Julia, Buendia, Izaskun, Martin, Yasmina B, Egea, Javier, Negredo, Pilar, Avendaño, Carlos
Published in Frontiers in molecular neuroscience (28.11.2016)
Published in Frontiers in molecular neuroscience (28.11.2016)
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Journal Article
The Antioxidant Additive Approach for Alzheimer’s Disease Therapy: New Ferulic (Lipoic) Acid Plus Melatonin Modified Tacrines as Cholinesterases Inhibitors, Direct Antioxidants, and Nuclear Factor (Erythroid-Derived 2)-Like 2 Activators
Benchekroun, Mohamed, Romero, Alejandro, Egea, Javier, León, Rafael, Michalska, Patrycja, Buendía, Izaskun, Jimeno, María Luisa, Jun, Daniel, Janockova, Jana, Sepsova, Vendula, Soukup, Ondrej, Bautista-Aguilera, Oscar, Refouvelet, Bernard, Ouari, Olivier, Marco-Contelles, José, Ismaili, Lhassane
Published in Journal of medicinal chemistry (10.11.2016)
Published in Journal of medicinal chemistry (10.11.2016)
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Journal Article