Reduction of Liver Steatosis and Fibrosis with an Ask1 Inhibitor in a Murine Model of Nash is Accompanied by Improvements in Cholesterol, Bile Acid and Lipid Metabolism
Budas, G, Karnik, S, Jonnson, T, Shafizadeh, T, Watkins, S, Breckenridge, D, Tumas, D
Published in Journal of hepatology (2016)
Published in Journal of hepatology (2016)
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Journal Article
Competitive inhibitors and allosteric activators of protein kinase C isoenzymes: a personal account and progress report on transferring academic discoveries to the clinic
Budas, G R, Koyanagi, T, Churchill, E N, Mochly-Rosen, D
Published in Biochemical Society transactions (01.11.2007)
Published in Biochemical Society transactions (01.11.2007)
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Journal Article
Deficiency of PDK1 in cardiac muscle results in heart failure and increased sensitivity to hypoxia
Mora, Alfonso, Davies, Anthony M., Bertrand, Luc, Sharif, Isam, Budas, Grant R., Jovanović, Sofija, Mouton, Véronique, Kahn, C. Ronald, Lucocq, John M., Gray, Gillian A., Jovanović, Aleksandar, Alessi, Dario R.
Published in The EMBO journal (15.09.2003)
Published in The EMBO journal (15.09.2003)
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Journal Article
20: The Resuscitated DCD Donor Heart Is Functionally Superior to the Brainstem Dead Donor Heart
Ali, A, Fajardo, G, Budas, G, Tsuda, S, Ali, Z, Quertermous, T, Bernstein, D, Tsui, S, Robbins, R, Fischbein, M, Large, S, Ashley, E
Published in The Journal of heart and lung transplantation (01.02.2009)
Published in The Journal of heart and lung transplantation (01.02.2009)
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Journal Article
Gender-specific difference in cardiac ATP-sensitive K+channels
Ranki, Harri J, Budas, Grant R, Crawford, Russell M, Jovanović, Aleksandar
Published in Journal of the American College of Cardiology (01.09.2001)
Published in Journal of the American College of Cardiology (01.09.2001)
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Journal Article
Characterization of ASK1 signaling in human NASH liver and human hepatic stellate cells
Budas, G., Wu, F., Turner, S., Zagorska, A., Li, L., Breckenridge, D.
Published in Journal of hepatology (01.04.2018)
Published in Journal of hepatology (01.04.2018)
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Journal Article
THU-491 - Characterization of ASK1 signaling in human NASH liver and human hepatic stellate cells
Budas, G., Wu, F., Turner, S., Zagorska, A., Li, L., Breckenridge, D.
Published in Journal of hepatology (01.04.2018)
Published in Journal of hepatology (01.04.2018)
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Journal Article
SAT-356 - Apoptosis signal-regulating kinase 1 (ASK1) inhibition reduces liver fibrosis and apoptosis in a NLRP3 mutant model of NASH
Schuster, S., McGeough, M.D., Johnson, C.D., Zagorska, A., Budas, G., Hoffman, H.M., Feldstein, A.E.
Published in Journal of hepatology (2017)
Published in Journal of hepatology (2017)
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Journal Article
D52 MOLECULAR INSIGHT INTO PULMONARY HYPERTENSION: Ask1 Inhibition Prevents Hypoxia-Induced Pulmonary Artery Fibroblast Activation And Paracrine Effects On Vascular Smooth Muscle Cells
Wilson, K S, Suveizdyte, K, Liles, J, Budas, G R, Peacock, A, Welsh, D J
Published in American journal of respiratory and critical care medicine (01.01.2016)
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Published in American journal of respiratory and critical care medicine (01.01.2016)
Journal Article
PS070 - Reduction of Liver Steatosis and Fibrosis with an Ask1 Inhibitor in a Murine Model of Nash is Accompanied by Improvements in Cholesterol, Bile Acid and Lipid Metabolism
Budas, G., Karnik, S., Jonnson, T., Shafizadeh, T., Watkins, S., Breckenridge, D., Tumas, D.
Published in Journal of hepatology (2016)
Published in Journal of hepatology (2016)
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Journal Article
FRI-077 - Combination of an FXR agonist and an ACC inhibitor increases anti-fibrotic efficacy in rodent models of NASH
Bates, J., Hollenback, D., Zagorska, A., Budas, G., Liles, J., Liu, H., Liu, K., Kusam, S., Brockett, R., Newstrom, D., Mikaelian, I., Wang, T., Ray, A., Breckenridge, D.
Published in Journal of hepatology (01.04.2018)
Published in Journal of hepatology (01.04.2018)
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Journal Article
Combination of an FXR agonist and an ACC inhibitor increases anti-fibrotic efficacy in rodent models of NASH
Bates, J., Hollenback, D., Zagorska, A., Budas, G., Liles, J., Liu, H., Liu, K., Kusam, S., Brockett, R., Newstrom, D., Mikaelian, I., Wang, T., Ray, A., Breckenridge, D.
Published in Journal of hepatology (01.04.2018)
Published in Journal of hepatology (01.04.2018)
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Journal Article
FRI-248 - The FXR agonist GS-9674 reduces fibrosis and portal hypertension in a rat model of NASH
Schwabl, P., Budas, G., Hambruch, E., Supper, P., Burnet, M., Liles, J., Sullivan, T., Huntzicker, E., Birkel, M., French, D., Tumas, D., Peck-Radosavljevic, M., Watkins, W., Trauner, M., Breckenridge, D., Kremoser, C., Reiberger, T.
Published in Journal of hepatology (01.04.2018)
Published in Journal of hepatology (01.04.2018)
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Journal Article
The FXR agonist GS-9674 reduces fibrosis and portal hypertension in a rat model of NASH
Schwabl, P., Budas, G., Hambruch, E., Supper, P., Burnet, M., Liles, J., Sullivan, T., Huntzicker, E., Birkel, M., French, D., Tumas, D., Peck-Radosavljevic, M., Watkins, W., Trauner, M., Breckenridge, D., Kremoser, C., Reiberger, T.
Published in Journal of hepatology (01.04.2018)
Published in Journal of hepatology (01.04.2018)
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Journal Article
C69 CONTROVERSY: ASSESSING AND TREATING THE FAILING RIGHT VENTRICLE: Progressive Right Ventricular Changes In A Sugen/hypoxic Rat Model Of Pulmonary Arterial Hypertension Determined By Cardiac Magnetic Resonance Imaging
Jayasekera, G, Wilson, K S, Buist, H, Liles, J, Budas, G R, Fairfax, S, Hughes, C, Nilsen, M, Church, C, Gallagher, L, Mullin, J, MacLean, M, Holmes, W, Welsh, D, Peacock, A
Published in American journal of respiratory and critical care medicine (01.01.2017)
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Published in American journal of respiratory and critical care medicine (01.01.2017)
Journal Article
D26 ASSESSMENT OF THE RIGHT VENTRICLE IN HEALTH AND DISEASE: Effects Of Apoptosis Signal- Regulating Kinase 1 (ask1) Inhibition In Experimental Pressure Overload-Induced Right Ventricular Dysfunction
Boehm, M, Kojonazarov, B, Ghofrani, H A, Grimminger, F, Weissmann, N, Liles, J, Budas, G R, Seeger, W, Schermuly, R T
Published in American journal of respiratory and critical care medicine (01.01.2015)
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Published in American journal of respiratory and critical care medicine (01.01.2015)
Journal Article
Overexpression of SUR2A generates a cardiac phenotype resistant to ischemia
Du, Qingyou, Jovanović, Sofija, Clelland, Allyson, Sukhodub, Andrey, Budas, Grant, Phelan, Karen, Murray-Tait, Victoria, Malone, Lorraine, Jovanović, Aleksandar
Published in The FASEB journal (01.06.2006)
Published in The FASEB journal (01.06.2006)
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