Mex3a Marks a Slowly Dividing Subpopulation of Lgr5+ Intestinal Stem Cells
Barriga, Francisco M., Montagni, Elisa, Mana, Miyeko, Mendez-Lago, Maria, Hernando-Momblona, Xavier, Sevillano, Marta, Guillaumet-Adkins, Amy, Rodriguez-Esteban, Gustavo, Buczacki, Simon J.A., Gut, Marta, Heyn, Holger, Winton, Douglas J., Yilmaz, Omer H., Attolini, Camille Stephan-Otto, Gut, Ivo, Batlle, Eduard
Published in Cell stem cell (01.06.2017)
Published in Cell stem cell (01.06.2017)
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Mouse models of colorectal cancer as preclinical models
McIntyre, Rebecca E, Buczacki, Simon J.A, Arends, Mark J, Adams, David J
Published in BioEssays (01.08.2015)
Published in BioEssays (01.08.2015)
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Journal Article
Itraconazole targets cell cycle heterogeneity in colorectal cancer
Buczacki, Simon J A, Popova, Semiramis, Biggs, Emma, Koukorava, Chrysa, Buzzelli, Jon, Vermeulen, Louis, Hazelwood, Lee, Francies, Hayley, Garnett, Mathew J, Winton, Douglas J
Published in The Journal of experimental medicine (02.07.2018)
Published in The Journal of experimental medicine (02.07.2018)
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Journal Article
5-hydroxymethylcytosine and gene activity in mouse intestinal differentiation
Uribe-Lewis, Santiago, Carroll, Thomas, Menon, Suraj, Nicholson, Anna, Manasterski, Piotr J., Winton, Douglas J., Buczacki, Simon J. A., Murrell, Adele
Published in Scientific reports (17.01.2020)
Published in Scientific reports (17.01.2020)
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Journal Article
Improving radiotherapy in immunosuppressive microenvironments by targeting complement receptor C5aR1
Beach, Callum, MacLean, David, Majorova, Dominika, Melemenidis, Stavros, Nambiar, Dhanya K, Kim, Ryan K, Valbuena, Gabriel N, Guglietta, Silvia, Krieg, Carsten, Darvish-Damavandi, Mahnaz, Suwa, Tatsuya, Easton, Alistair, Hillson, Lily Vs, McCulloch, Ashley K, McMahon, Ross K, Pennel, Kathryn, Edwards, Joanne, O'Cathail, Sean M, Roxburgh, Campbell S, Domingo, Enric, Moon, Eui Jung, Jiang, Dadi, Jiang, Yanyan, Zhang, Qingyang, Koong, Albert C, Woodruff, Trent M, Graves, Edward E, Maughan, Tim, Buczacki, Simon Ja, Stucki, Manuel, Le, Quynh-Thu, Leedham, Simon J, Giaccia, Amato J, Olcina, Monica M
Published in The Journal of clinical investigation (01.12.2023)
Published in The Journal of clinical investigation (01.12.2023)
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Journal Article
Mutational landscape of normal epithelial cells in Lynch Syndrome patients
Lee, Bernard C. H., Robinson, Philip S., Coorens, Tim H. H., Yan, Helen H. N., Olafsson, Sigurgeir, Lee-Six, Henry, Sanders, Mathijs A., Siu, Hoi Cheong, Hewinson, James, Yue, Sarah S. K., Tsui, Wai Yin, Chan, Annie S. Y., Chan, Anthony K. W., Ho, Siu Lun, Campbell, Peter J., Martincorena, Inigo, Buczacki, Simon J. A., Yuen, Siu Tsan, Leung, Suet Yi, Stratton, Michael R.
Published in Nature communications (17.05.2022)
Published in Nature communications (17.05.2022)
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Journal Article
Inherited MUTYH mutations cause elevated somatic mutation rates and distinctive mutational signatures in normal human cells
Robinson, Philip S., Thomas, Laura E., Abascal, Federico, Jung, Hyunchul, Harvey, Luke M. R., West, Hannah D., Olafsson, Sigurgeir, Lee, Bernard C. H., Coorens, Tim H. H., Lee-Six, Henry, Butlin, Laura, Lander, Nicola, Truscott, Rebekah, Sanders, Mathijs A., Lensing, Stefanie V., Buczacki, Simon J. A., ten Hoopen, Rogier, Coleman, Nicholas, Brunton-Sim, Roxanne, Rushbrook, Simon, Saeb-Parsy, Kourosh, Lalloo, Fiona, Campbell, Peter J., Martincorena, Iñigo, Sampson, Julian R., Stratton, Michael R.
Published in Nature communications (08.07.2022)
Published in Nature communications (08.07.2022)
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Journal Article
Primary tumour immune response and lymph node yields in colon cancer
Lal, Nikhil, Chan, Dedrick Kok Hong, Ng, Minn E, Vermeulen, Louis, Buczacki, Simon James Alexander
Published in British journal of cancer (03.05.2022)
Published in British journal of cancer (03.05.2022)
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Journal Article
Defining Stem Cell Dynamics in Models of Intestinal Tumor Initiation
Vermeiden, Louis, Morrissey, Edward, van der Heijden, Maartje, Nicholson, Anna M., Sottoriva, Andrea, Buczacki, Simon, Kemp, Richard, Tavaré, Simon, Winton, Douglas J.
Published in Science (American Association for the Advancement of Science) (22.11.2013)
Published in Science (American Association for the Advancement of Science) (22.11.2013)
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An analysis of SARS‐CoV‐2 cell entry genes identifies the intestine and colorectal cancer as susceptible tissues
Darvish‐Damavandi, Mahnaz, Laycock, James, Ward, Christopher, Driel, Milou S, Goldgraben, Mae A, Buczacki, Simon JA
Published in British journal of surgery (01.10.2020)
Published in British journal of surgery (01.10.2020)
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Journal Article
Tumour heterogeneity and evolutionary dynamics in colorectal cancer
Chan, Dedrick Kok Hong, Buczacki, Simon James Alexander
Published in Oncogenesis (New York, NY) (16.07.2021)
Published in Oncogenesis (New York, NY) (16.07.2021)
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Journal Article
CARE: Protocol of a randomised trial evaluating the feasibility of preoperative intentional weight loss to support postoperative recovery in patients with excess weight and colorectal cancer
Koutoukidis, Dimitrios A, Jebb, Susan A, Foster, Claire, Wheatstone, Pete, Horne, Alison, Hill, T Martyn, Taylor, Amy, Realpe, Alba, Achana, Felix, Buczacki, Simon J A
Published in Colorectal disease (01.09.2023)
Published in Colorectal disease (01.09.2023)
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Journal Article
Improving radiotherapy in immunosuppressive microenvironments by targeting complement receptor C5aR1
Beach, Callum, MacLean, David, Majorova, Dominika, Melemenidis, Stavros, Nambiar, Dhanya K, Kim, Ryan K, Valbuena, Gabriel N, Guglietta, Silvia, Krieg, Carsten, Darvish-Damavandi, Mahnaz, Suwa, Tatsuya, Easton, Alistair, Hillson, Lily Vs, McCulloch, Ashley K, McMahon, Ross K, Pennel, Kathryn, Edwards, Joanne, O'Cathail, Sean M, Roxburgh, Campbell S, Domingo, Enric, Moon, Eui Jung, Jiang, Dadi, Jiang, Yanyan, Zhang, Qingyang, Koong, Albert C, Woodruff, Trent M, Graves, Edward E, Maughan, Tim, Buczacki, Simon Ja, Stucki, Manuel, Le, Quynh-Thu, Leedham, Simon J, Giaccia, Amato J, Olcina, Monica M
Published in The Journal of clinical investigation (15.08.2024)
Published in The Journal of clinical investigation (15.08.2024)
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Journal Article
An innate IL-25-ILC2-MDSC axis creates a cancer-permissive microenvironment for Apc mutation-driven intestinal tumorigenesis
Jou, Eric, Rodriguez-Rodriguez, Noe, Ferreira, Ana-Carolina F, Jolin, Helen E, Clark, Paula A, Sawmynaden, Kovilen, Ko, Michelle, Murphy, Jane E, Mannion, Jonathan, Ward, Christopher, Matthews, David J, Buczacki, Simon J A, McKenzie, Andrew N J
Published in Science immunology (03.06.2022)
Published in Science immunology (03.06.2022)
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Journal Article
Myoferlin: A Potential Marker of Response to Radiation Therapy and Survival in Locally Advanced Rectal Cancer
Fowler, Hayley, Clifford, Rachael E., Bowden, David, Sutton, Paul A., Govindarajah, Naren, Fok, Matthew, Glenn, Mark, Wall, Michael, Rubbi, Carlos, Buczacki, Simon J.A., Mandal, Amit, Francies, Hayley, Hughes, Jonathan, Parsons, Jason L., Vimalachandran, Dale
Published in International journal of radiation oncology, biology, physics (10.06.2024)
Published in International journal of radiation oncology, biology, physics (10.06.2024)
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Journal Article
Multipotent Basal Stem Cells, Maintained in Localized Proximal Niches, Support Directed Long-Ranging Epithelial Flows in Human Prostates
Moad, Mohammad, Hannezo, Edouard, Buczacki, Simon J., Wilson, Laura, El-Sherif, Amira, Sims, David, Pickard, Robert, Wright, Nicholas A., Williamson, Stuart C., Turnbull, Doug M., Taylor, Robert W., Greaves, Laura, Robson, Craig N., Simons, Benjamin D., Heer, Rakesh
Published in Cell reports (Cambridge) (15.08.2017)
Published in Cell reports (Cambridge) (15.08.2017)
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Journal Article
Isolation of Human Colon Stem Cells Using Surface Expression of PTK7
Jung, Peter, Sommer, Christian, Barriga, Francisco M., Buczacki, Simon J., Hernando-Momblona, Xavier, Sevillano, Marta, Duran-Frigola, Miquel, Aloy, Patrick, Selbach, Matthias, Winton, Douglas J., Batlle, Eduard
Published in Stem cell reports (08.12.2015)
Published in Stem cell reports (08.12.2015)
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Journal Article
Participants' perspectives of being recruited into a randomised trial of a weight loss intervention before colorectal cancer surgery: a qualitative interview study
Talbot, Amelia, Jebb, Susan A, Foster, Claire, Realpe, Alba X, Wheatstone, Pete, Buczacki, Simon, Koutoukidis, Dimitrios A
Published in BMC cancer (05.07.2024)
Published in BMC cancer (05.07.2024)
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