Synthesis and Structure–Activity Relationships of 5,6,7-Substituted Pyrazolopyrimidines: Discovery of a Novel TSPO PET Ligand for Cancer Imaging
Tang, Dewei, McKinley, Eliot T, Hight, Matthew R, Uddin, Md. Imam, Harp, Joel M, Fu, Allie, Nickels, Michael L, Buck, Jason R, Manning, H. Charles
Published in Journal of medicinal chemistry (25.04.2013)
Published in Journal of medicinal chemistry (25.04.2013)
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Preclinical TSPO Ligand PET to Visualize Human Glioma Xenotransplants: A Preliminary Study
Buck, Jason R, McKinley, Eliot T, Fu, Allie, Abel, Ty W, Thompson, Reid C, Chambless, Lola, Watchmaker, Jennifer M, Harty, James P, Cooper, Michael K, Manning, H Charles
Published in PloS one (30.10.2015)
Published in PloS one (30.10.2015)
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Evaluation of TSPO PET Ligands [18F]VUIIS1009A and [18F]VUIIS1009B: Tracers for Cancer Imaging
Tang, Dewei, Li, Jun, Buck, Jason R., Tantawy, Mohamed Noor, Xia, Yan, Harp, Joel M., Nickels, Michael L., Meiler, Jens, Manning, H. Charles
Published in Molecular imaging and biology (01.08.2017)
Published in Molecular imaging and biology (01.08.2017)
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Quantitative preclinical imaging of TSPO expression in glioma using N,N-diethyl-2-(2-(4-(2-18F-fluoroethoxy)phenyl)-5,7-dimethylpyrazolo[1,5-a]pyrimidin-3-yl)acetamide
Tang, Dewei, Hight, Matthew R, McKinley, Eliot T, Fu, Allie, Buck, Jason R, Smith, R Adam, Tantawy, Mohammed Noor, Peterson, Todd E, Colvin, Daniel C, Ansari, M Sib, Nickels, Michael, Manning, H Charles
Published in Journal of Nuclear Medicine (01.02.2012)
Published in Journal of Nuclear Medicine (01.02.2012)
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Design and synthesis of isoform-selective phospholipase D (PLD) inhibitors. Part I: Impact of alternative halogenated privileged structures for PLD1 specificity
Lewis, Jana A., Scott, Sarah A., Lavieri, Robert, Buck, Jason R., Selvy, Paige E., Stoops, Sydney L., Armstrong, Michelle D., Brown, H. Alex, Lindsley, Craig W.
Published in Bioorganic & medicinal chemistry letters (01.04.2009)
Published in Bioorganic & medicinal chemistry letters (01.04.2009)
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Imaging Biomarkers Predict Response to Anti-HER2 (ErbB2) Therapy in Preclinical Models of Breast Cancer
SHAH, Chirayu, MILLER, Todd W, BALDWIN, Ronald M, GORE, John C, SCHIFF, Rachel, ARTEAGA, Carlos L, MANNING, H. Charles, WYATT, Shelby K, MCKINLEY, EliotT, GRACIELA OLIVARES, Maria, SANCHEZ, Violeta, NOLTING, Donald D, BUCK, Jason R, PING ZHAO, SIB ANSARI, M
Published in Clinical cancer research (15.07.2009)
Published in Clinical cancer research (15.07.2009)
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Design of isoform-selective phospholipase D inhibitors that modulate cancer cell invasiveness
Brown, H Alex, Scott, Sarah A, Selvy, Paige E, Buck, Jason R, Cho, Hyekyung P, Criswell, Tracy L, Thomas, Ashley L, Armstrong, Michelle D, Arteaga, Carlos L, Lindsley, Craig W
Published in Nature chemical biology (01.02.2009)
Published in Nature chemical biology (01.02.2009)
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N-[18F]-Fluoroacetylcrizotinib: A potentially potent and selective PET tracer for molecular imaging of non-small cell lung cancer
Buck, Jason R., Saleh, Samir, Claus, Trey, Lovly, Christine, Hight, Matthew R., Nickels, Michael L., Noor Tantawy, M., Charles Manning, H.
Published in Bioorganic & medicinal chemistry letters (15.08.2020)
Published in Bioorganic & medicinal chemistry letters (15.08.2020)
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Preclinical Imaging Evaluation of Novel TSPO-PET Ligand 2-(5,7-Diethyl-2-(4-(2-[18F]fluoroethoxy)phenyl)pyrazolo[1,5-a]pyrimidin-3-yl)-N,N-diethylacetamide ([18F]VUIIS1008) in Glioma
Tang, Dewei, Nickels, Michael L., Tantawy, M. Noor, Buck, Jason R., Manning, H. Charles
Published in Molecular imaging and biology (01.12.2014)
Published in Molecular imaging and biology (01.12.2014)
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Journal Article
Preclinical Evaluation of 4-[18F]Fluoroglutamine PET to Assess ASCT2 Expression in Lung Cancer
Hassanein, Mohamed, Hight, Matthew R., Buck, Jason R., Tantawy, Mohammed N., Nickels, Michael L., Hoeksema, Megan D., Harris, Bradford K., Boyd, Kelli, Massion, Pierre P., Manning, H. Charles
Published in Molecular imaging and biology (01.02.2016)
Published in Molecular imaging and biology (01.02.2016)
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A Peptide-Based Positron Emission Tomography Probe for In Vivo Detection of Caspase Activity in Apoptotic Cells
HIGHT, Matthew R, CHEUNG, Yiu-Yin, MANNING, H. Charles, NICKELS, Michael L, DAWSON, Eric S, PING ZHAO, SALEH, Samir, BUCK, Jason R, DEWEI TANG, WASHINGTON, M. Kay, COFFEY, Robert J
Published in Clinical cancer research (15.04.2014)
Published in Clinical cancer research (15.04.2014)
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Journal Article
Rapid, microwave-assisted organic synthesis of selective (V600E)BRAF inhibitors for preclinical cancer research
Buck, Jason R., Saleh, Sam, Uddin, Md Imam, Manning, H. Charles
Published in Tetrahedron letters (08.08.2012)
Published in Tetrahedron letters (08.08.2012)
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Stereocontrolled Syntheses of Deoxyribonucleosides via Photoinduced Electron-Transfer Deoxygenation of Benzoyl-Protected Ribo- and Arabinonucleosides
Wang, Zhiwei, Prudhomme, Daniel R, Buck, Jason R, Park, Minnie, Rizzo, Carmelo J
Published in Journal of organic chemistry (22.09.2000)
Published in Journal of organic chemistry (22.09.2000)
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Microwave-assisted, one-pot reaction of 7-azaindoles and aldehydes: a facile route to novel di-7-azaindolylmethanes
Uddin, Md. Imam, Buck, Jason R., Schulte, Michael L., Tang, Dewei, Saleh, Samir A., Cheung, Yiu-Yin, Harp, Joel, Manning, H. Charles
Published in Tetrahedron letters (01.01.2014)
Published in Tetrahedron letters (01.01.2014)
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Journal Article
Microwave-assisted organic synthesis of a high-affinity pyrazolo-pyrimidinyl TSPO ligand
Tang, Dewei, Buck, Jason R., Hight, Matthew R., Manning, H. Charles
Published in Tetrahedron letters (01.09.2010)
Published in Tetrahedron letters (01.09.2010)
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Journal Article
High-yielding, automated production of 3′-deoxy-3′-[18F]fluorothymidine using a modified Bioscan Coincidence FDG reaction module
Cheung, Yiu-Yin, Nickels, Michael L., McKinley, Eliot T., Buck, Jason R., Manning, H. Charles
Published in Applied radiation and isotopes (01.03.2015)
Published in Applied radiation and isotopes (01.03.2015)
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Journal Article
150 Mutant KRAS-Dependent Changes in Exosomes and Recipient Cell Metabolism
Beckler, Michelle Demory, Higginbotham, James N, Franklin, Jeff, Halvey, Patrick J, Ham, Amy-Joan L, Liebler, Daniel C, Li, Ming, Buck, Jason R, Manning, H. Charles, Walsh, Alex J, Skala, Melissa C, Coffey, Robert J
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2013)
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2013)
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Quantitative, preclinical PET of translocator protein expression in glioma using 18F-N-fluoroacetyl-N-(2,5-dimethoxybenzyl)-2-phenoxyaniline
Buck, Jason R, McKinley, Eliot T, Hight, Matthew R, Fu, Allie, Tang, Dewei, Smith, Ralph Adam, Tantawy, Mohammed Noor, Peterson, Todd E, Colvin, Daniel, Ansari, Mohammed Sib, Baldwin, Ronald M, Zhao, Ping, Guleryuz, Saffet, Manning, H Charles
Published in The Journal of nuclear medicine (1978) (01.01.2011)
Published in The Journal of nuclear medicine (1978) (01.01.2011)
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