The multi-receptor inhibitor axitinib reverses tumor-induced immunosuppression and potentiates treatment with immune-modulatory antibodies in preclinical murine models
Läubli, Heinz, Müller, Philipp, D’Amico, Lucia, Buchi, Mélanie, Kashyap, Abhishek S., Zippelius, Alfred
Published in Cancer Immunology, Immunotherapy (01.05.2018)
Published in Cancer Immunology, Immunotherapy (01.05.2018)
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Optimized antiangiogenic reprogramming of the tumor microenvironment potentiates CD40 immunotherapy
Kashyap, Abhishek S., Schmittnaegel, Martina, Rigamonti, Nicolò, Pais-Ferreira, Daniela, Mueller, Philipp, Buchi, Melanie, Ooi, Chia-Huey, Kreuzaler, Matthias, Hirschmann, Petra, Guichard, Alan, Rieder, Natascha, Bill, Ruben, Herting, Frank, Kienast, Yvonne, Dirnhofer, Stefan, Klein, Christian, Hoves, Sabine, Ries, Carola H., Corse, Emily, De Palma, Michele, Zippelius, Alfred
Published in Proceedings of the National Academy of Sciences - PNAS (07.01.2020)
Published in Proceedings of the National Academy of Sciences - PNAS (07.01.2020)
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Deletion of SNX9 alleviates CD8 T cell exhaustion for effective cellular cancer immunotherapy
Trefny, Marcel P., Kirchhammer, Nicole, Auf der Maur, Priska, Natoli, Marina, Schmid, Dominic, Germann, Markus, Fernandez Rodriguez, Laura, Herzig, Petra, Lötscher, Jonas, Akrami, Maryam, Stinchcombe, Jane C., Stanczak, Michal A., Zingg, Andreas, Buchi, Melanie, Roux, Julien, Marone, Romina, Don, Leyla, Lardinois, Didier, Wiese, Mark, Jeker, Lukas T., Bentires-Alj, Mohamed, Rossy, Jérémie, Thommen, Daniela S., Griffiths, Gillian M., Läubli, Heinz, Hess, Christoph, Zippelius, Alfred
Published in Nature communications (02.02.2023)
Published in Nature communications (02.02.2023)
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Plinabulin, a Distinct Microtubule-Targeting Chemotherapy, Promotes M1-Like Macrophage Polarization and Anti-tumor Immunity
Natoli, Marina, Herzig, Petra, Pishali Bejestani, Elham, Buchi, Melanie, Ritschard, Reto, Lloyd, G Kenneth, Mohanlal, Ramon, Tonra, James R, Huang, Lan, Heinzelmann, Viola, Trüb, Marta, Zippelius, Alfred, Kashyap, Abhishek S
Published in Frontiers in oncology (03.03.2021)
Published in Frontiers in oncology (03.03.2021)
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Antisense oligonucleotide targeting CD39 improves anti-tumor T cell immunity
Kashyap, Abhishek S, Thelemann, Tamara, Klar, Richard, Kallert, Sandra M, Festag, Julia, Buchi, Melanie, Hinterwimmer, Lisa, Schell, Monika, Michel, Sven, Jaschinski, Frank, Zippelius, Alfred
Published in Journal for immunotherapy of cancer (12.03.2019)
Published in Journal for immunotherapy of cancer (12.03.2019)
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Neuropeptide S receptor deficiency modulates spontaneous locomotor activity and the acoustic startle response
Fendt, Markus, Buchi, Mélanie, Bürki, Hugo, Imobersteg, Stefan, Ricoux, Bérangère, Suply, Thomas, Sailer, Andreas W.
Published in Behavioural brain research (02.02.2011)
Published in Behavioural brain research (02.02.2011)
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881 Knockdown of neuropilin-1 by third generation antisense oligonucleotides has strong antitumor activity that can be further increased by combination with immune checkpoint inhibitors
Maaske, André, Kirchhammer, Nicole, Festag, Julia, Rodriguez, Laura Fernandez, Buchi, Melanie, Schell, Monika, Raith, Stefanie, Michel, Sven, Klar, Richard, Zippelius, Alfred, Jaschinski, Frank
Published in Journal for immunotherapy of cancer (01.11.2023)
Published in Journal for immunotherapy of cancer (01.11.2023)
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Synchronous Evolution of an Odor Biosynthesis Pathway and Behavioral Response
Li, Qian, Korzan, Wayne J., Ferrero, David M., Chang, Rui B., Roy, Dheeraj S., Buchi, Mélanie, Lemon, Jamie K., Kaur, Angeldeep W., Stowers, Lisa, Fendt, Markus, Liberles, Stephen D.
Published in Current biology (07.01.2013)
Published in Current biology (07.01.2013)
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A novel anti-HER2 anthracycline-based antibody-drug conjugate induces adaptive anti-tumor immunity and potentiates PD-1 blockade in breast cancer
D'Amico, Lucia, Menzel, Ulrike, Prummer, Michael, Müller, Philipp, Buchi, Mélanie, Kashyap, Abhishek, Haessler, Ulrike, Yermanos, Alexander, Gébleux, Rémy, Briendl, Manfred, Hell, Tamara, Wolter, Fabian I, Beerli, Roger R, Truxova, Iva, Radek, Špíšek, Vlajnic, Tatjana, Grawunder, Ulf, Reddy, Sai, Zippelius, Alfred
Published in Journal for immunotherapy of cancer (21.01.2019)
Published in Journal for immunotherapy of cancer (21.01.2019)
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Dual TLR9 and PD-L1 targeting unleashes dendritic cells to induce durable antitumor immunity
Fernandez-Rodriguez, Laura, Cianciaruso, Chiara, Bill, Ruben, Trefny, Marcel P, Klar, Richard, Kirchhammer, Nicole, Buchi, Mélanie, Festag, Julia, Michel, Sven, Kohler, Rainer H, Jones, Elham, Maaske, Andre, Kashyap, Abhishek S, Jaschinski, Frank, Dixon, Karen O, Pittet, Mikael J, Zippelius, Alfred
Published in Journal for immunotherapy of cancer (01.05.2023)
Published in Journal for immunotherapy of cancer (01.05.2023)
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Abstract 5030: Microtubule destabilization by plinabulin generates anti-tumor immune response through repolarization of intratumoral macrophages
Bejestani, Elham Pishali, Lloyd, G. Kenneth, Buchi, Melanie, Ritschard, Reto, Herzig, Petra, Mohanlal, Ramon, Huang, Lan, Tonra, James R., Zippelius, Alfred, Kashyap, Abhishek
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Abstract 5021: LNAplusTM antisense oligonucleotides targeting CD39 and CD73 have potent anti-tumor activity by modulating immunosuppressive tumor microenvironment
Festag, Julia, Thelemann, Tamara, Kashyap, Abhishek S., Klar, Richard, Kallert, Sandra, Buchi, Melanie, Hinterwimmer, Lisa, Schell, Monika, Raith, Stefanie, Michel, Sven, Zippelius, Alfred, Jaschinski, Frank
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Abstract 4149: Knock-down of Neuropilin-1 by locked nucleic acid antisense oligonucleotides facilitates cancer immune control
Maaske, Andre, Kirchhammer, Nicole, Festag, Julia, Rodriguez, Laura Fernandez, Buchi, Mélanie, Schell, Monika, Raith, Stefanie, Michel, Sven, Klar, Richard, Zippelius, Alfred, Jaschinski, Frank
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
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