Search Results - "Bu, Yahao" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Discovery of Novel Dual Mechanism of Action Src Signaling and Tubulin Polymerization Inhibitors (KX2-391 and KX2-361)

Discovery of Novel Dual Mechanism of Action Src Signaling and Tubulin Polymerization Inhibitors (KX2-391 and KX2-361)

by Smolinski, Michael P, Bu, Yahao, Clements, James, Gelman, Irwin H, Hegab, Taher, Cutler, David L, Fang, Jane W. S, Fetterly, Gerald, Kwan, Rudolf, Barnett, Allen, Lau, Johnson Y. N, Hangauer, David G
Published in Journal of medicinal chemistry (14.06.2018)

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Journal Article

SSeCKS/Gravin/AKAP12 Inhibits Cancer Cell Invasiveness and Chemotaxis by Suppressing a Protein Kinase C- Raf/MEK/ERK Pathway

SSeCKS/Gravin/AKAP12 Inhibits Cancer Cell Invasiveness and Chemotaxis by Suppressing a Protein Kinase C- Raf/MEK/ERK Pathway

by Su, Bing, Bu, Yahao, Engelberg, David, Gelman, Irwin H
Published in The Journal of biological chemistry (12.02.2010)

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Journal Article

Thiazolyl N-benzyl-substituted acetamide derivatives: Synthesis, Src kinase inhibitory and anticancer activities

Thiazolyl N-benzyl-substituted acetamide derivatives: Synthesis, Src kinase inhibitory and anticancer activities

by Fallah-Tafti, Asal, Foroumadi, Alireza, Tiwari, Rakesh, Shirazi, Amir Nasrolahi, Hangauer, David G., Bu, Yahao, Akbarzadeh, Tahmineh, Parang, Keykavous, Shafiee, Abbas
Published in European journal of medicinal chemistry (01.10.2011)

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Journal Article

Paxillin-Y118 phosphorylation contributes to the control of Src-induced anchorage-independent growth by FAK and adhesion

Paxillin-Y118 phosphorylation contributes to the control of Src-induced anchorage-independent growth by FAK and adhesion

by Sachdev, Sanjay, Bu, Yahao, Gelman, Irwin H
Published in BMC cancer (12.01.2009)

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Journal Article

An ion-current-based, comprehensive and reproducible proteomic strategy for comparative characterization of the cellular responses to novel anti-cancer agents in a prostate cell model

An ion-current-based, comprehensive and reproducible proteomic strategy for comparative characterization of the cellular responses to novel anti-cancer agents in a prostate cell model

by Tu, Chengjian, Li, Jun, Bu, Yahao, Hangauer, David, Qu, Jun
Published in Journal of proteomics (21.12.2012)

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Journal Article

v-Src-mediated Down-regulation of SSeCKS Metastasis Suppressor Gene Promoter by the Recruitment of HDAC1 into a USF1-Sp1-Sp3 Complex

v-Src-mediated Down-regulation of SSeCKS Metastasis Suppressor Gene Promoter by the Recruitment of HDAC1 into a USF1-Sp1-Sp3 Complex

by Bu, Yahao, Gelman, Irwin H.
Published in The Journal of biological chemistry (14.09.2007)

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Journal Article

SSeCKS metastasis-suppressing activity in matlylu prostate cancer cells correlates with vascular endothelial growth factor inhibition

SSeCKS metastasis-suppressing activity in matlylu prostate cancer cells correlates with vascular endothelial growth factor inhibition

by BING SU, QIAO ZHENG, VAUGHAN, Mary M, YAHAO BU, GELMAN, Irwin H
Published in Cancer research (Chicago, Ill.) (01.06.2006)

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Journal Article

Discovery and Characterization of Potent Dual P‑Glycoprotein and CYP3A4 Inhibitors: Design, Synthesis, Cryo-EM Analysis, and Biological Evaluations

Discovery and Characterization of Potent Dual P‑Glycoprotein and CYP3A4 Inhibitors: Design, Synthesis, Cryo-EM Analysis, and Biological Evaluations

by Urgaonkar, Sameer, Nosol, Kamil, Said, Ahmed M, Nasief, Nader N, Bu, Yahao, Locher, Kaspar P, Lau, Johnson Y. N, Smolinski, Michael P
Published in Journal of medicinal chemistry (13.01.2022)

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Journal Article

Abstract 4717: Effective preclinical management of angiosarcoma with oral paclitaxel

Abstract 4717: Effective preclinical management of angiosarcoma with oral paclitaxel

by Cutler, Murray J., Belko, Krista E., Bu, Yahao, Verone-Boyle, Alissa R., Cutler, David, Chan, Wing-Kai, Kwan, Rudolf, Lau, Johnson Y., Smolinski, Michael P.
Published in Cancer research (Chicago, Ill.) (01.07.2019)

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Journal Article

Ion Current-Based Proteomic Profiling for Understanding the Inhibitory Effect of Tumor Necrosis Factor Alpha on Myogenic Differentiation

Ion Current-Based Proteomic Profiling for Understanding the Inhibitory Effect of Tumor Necrosis Factor Alpha on Myogenic Differentiation

by Tu, Chengjian, Bu, Yahao, Vujcic, Marija, Shen, Shichen, Li, Jun, Qu, Miao, Hangauer, David, Clements, James L, Qu, Jun
Published in Journal of proteome research (02.09.2016)

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Journal Article

KX2-361: a novel orally bioavailable small molecule dual Src/tubulin inhibitor that provides long term survival in a murine model of glioblastoma

KX2-361: a novel orally bioavailable small molecule dual Src/tubulin inhibitor that provides long term survival in a murine model of glioblastoma

by Ciesielski, Michael J., Bu, Yahao, Munich, Stephan A., Teegarden, Paola, Smolinski, Michael P., Clements, James L., Lau, Johnson Y. N., Hangauer, David G., Fenstermaker, Robert A.
Published in Journal of neuro-oncology (01.12.2018)

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Journal Article

Peptidomimetic Src/pretubulin inhibitor KX-01 alone and in combination with paclitaxel suppresses growth, metastasis in human ER/PR/HER2-negative tumor xenografts

Peptidomimetic Src/pretubulin inhibitor KX-01 alone and in combination with paclitaxel suppresses growth, metastasis in human ER/PR/HER2-negative tumor xenografts

by Anbalagan, Muralidharan, Ali, Alaa, Jones, Ryan K, Marsden, Carolyn G, Sheng, Mei, Carrier, Latonya, Bu, Yahao, Hangauer, David, Rowan, Brian G
Published in Molecular cancer therapeutics (01.09.2012)

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Journal Article

Role for transcription factor TFII‐I in the suppression of SSeCKS/Gravin/Akap12 transcription by Src

Role for transcription factor TFII‐I in the suppression of SSeCKS/Gravin/Akap12 transcription by Src

by Bu, Yahao, Gao, Lingqiu, Gelman, Irwin H.
Published in International journal of cancer (15.04.2011)

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Journal Article

Abstract 2534: Suppression of prostate cancer growth by the Src signaling inhibitor, KXO1 (KX2-391)

Abstract 2534: Suppression of prostate cancer growth by the Src signaling inhibitor, KXO1 (KX2-391)

by Bu, Yahao, Gao, Lingqiu, Hangauer, David, Gelman, Irwin H.
Published in Cancer research (Chicago, Ill.) (15.04.2010)

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Journal Article

SSeCKS/Gravin/AKAP12 Inhibits Cancer Cell Invasiveness and Chemotaxis by Suppressing a Protein Kinase C- Raf/MEK/ERK Pathway2

SSeCKS/Gravin/AKAP12 Inhibits Cancer Cell Invasiveness and Chemotaxis by Suppressing a Protein Kinase C- Raf/MEK/ERK Pathway2

by Su, Bing, Bu, Yahao, Engelberg, David, Gelman, Irwin H.
Published in The Journal of biological chemistry (12.02.2010)

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Journal Article

Compositions and methods for treating hyperproliferative skin disorders

Compositions and methods for treating hyperproliferative skin disorders

by Lau, Johnson Yiu-Nam, Bu, Yahao, Cutler, Murray John, Kwan, Min-Fun Rudolf, Belko, Krista Elizabeth, Verone-Boyle, Alissa Rae, Wong, Chun-Ho
Year of Publication 12.09.2023

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Patent

Compositions and Methods for Treating Hyperproliferative Skin Disorders

Compositions and Methods for Treating Hyperproliferative Skin Disorders

by Lau, Johnson Yiu-Nam, Bu, Yahao, Cutler, Murray John, Kwan, Min-Fun Rudolf, Belko, Krista Elizabeth, Verone-Boyle, Alissa Rae, Wong, Chun-Ho
Year of Publication 11.02.2021

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Patent

Abstract 2487: Mechanism of action KX01 (KX2-391), a novel tubulin polymerization and Src signaling inhibitor proceeding to Phase II clinical trials

Abstract 2487: Mechanism of action KX01 (KX2-391), a novel tubulin polymerization and Src signaling inhibitor proceeding to Phase II clinical trials

by BU, YAHAO, Smolinski, Michael, Qu, Jun, Kazim, Latif, Gelman, Irwin, Dyster, Lyn, Hangauer, David
Published in Cancer research (Chicago, Ill.) (15.04.2010)

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Journal Article

COMPOSITIONS AND METHODS FOR TREATING HYPERPROLIFERATIVE SKIN DISORDERS

COMPOSITIONS AND METHODS FOR TREATING HYPERPROLIFERATIVE SKIN DISORDERS

by KWAN, Min-Fun Rudolf, CUTLER, Murray John, WONG, Chun-Ho, BU, Yahao, LAU, Johnson Yiu-Nam, BELKO, Krista Elizabeth, VERONE-BOYLE, Alissa Rae
Year of Publication 29.12.2021

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Patent

COMPOSITIONS AND METHODS FOR TREATING HYPERPROLIFERATIVE SKIN DISORDERS

COMPOSITIONS AND METHODS FOR TREATING HYPERPROLIFERATIVE SKIN DISORDERS

by KWAN, Min-Fun Rudolf, CUTLER, Murray John, WONG, Chun-Ho, BU, Yahao, LAU, Johnson Yiu-Nam, BELKO, Krista Elizabeth, VERONE-BOYLE, Alissa Rae
Year of Publication 13.01.2021

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Patent