The supramolecular self-assembly of 5-fluorouracil and caffeic acid through cocrystallization strategy opens up a new way for the development of synergistic antitumor pharmaceutical cocrystal
Yu, Yue-Ming, Wang, Ling-Yang, Bu, Fan-Zhi, Wang, Lin-Lin, Li, Yan-Tuan, Wang, Cheng, Wu, Zhi-Yong
Published in CrystEngComm (07.12.2020)
Published in CrystEngComm (07.12.2020)
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Journal Article
Salification-driven strategy toward the hydrophobic molecular salt of the antifungal drug 5-fluorocytosine and protocatechuic acid with triple-helix structure offers an innovative insight for conquering adverse drug reactions
Bu, Fan-Zhi, Yu, Yue-Ming, Zhang, Lin-Lin, Yan, Cui-Wei, Wu, Zhi-Yong, Li, Yan-Tuan
Published in CrystEngComm (27.03.2023)
Published in CrystEngComm (27.03.2023)
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Journal Article
Self-assembly of antifungal agent 5-fluorocytosine and nutrient trans-p -coumaric acid furnishes a cocrystal with the potential to reduce toxicity and side effects for the drug: a case study combining theory with experiment
Bu, Fan-Zhi, Yu, Yue-Ming, Yu, Yu, Yan, Cui-Wei, Wu, Zhi-Yong, Li, Yan-Tuan
Published in New journal of chemistry (16.01.2023)
Published in New journal of chemistry (16.01.2023)
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Journal Article
Drug-nutrient cocrystallization-driven strategy towards self-assembly of milrinone and ferulic acid provides an exemplification in perfecting in vitro / vivo characteristics of anti-heart failure drugs
Liu, Lu, Yu, Yue-Ming, Yu, Yu, Bu, Fan-Zhi, Wu, Zhi-Yong, Yan, Cui-Wei, Li, Yan-Tuan
Published in New journal of chemistry (30.05.2022)
Published in New journal of chemistry (30.05.2022)
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Journal Article
The First Cocrystallization of Milrinone with Nutraceuticals: The Adjusting Effects of Hydrophilicity/Hydrophobicity in Cavities on the In Vitro/In Vivo Properties of the Cocrystals
Liu, Lu, Yu, Yue-Ming, Bu, Fan-Zhi, Li, Yan-Tuan, Yan, Cui-Wei, Wu, Zhi-Yong
Published in Crystal growth & design (02.03.2022)
Published in Crystal growth & design (02.03.2022)
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Journal Article
A novice cocrystal nanomicelle formulation of 5-fluorouracil with proline: The design, self-assembly and in vitro/vivo biopharmaceutical characteristics
Yu, Yue-Ming, Liu, Lu, Bu, Fan-Zhi, Li, Yan-Tuan, Yan, Cui-Wei, Wu, Zhi-Yong
Published in International journal of pharmaceutics (05.04.2022)
Published in International journal of pharmaceutics (05.04.2022)
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Journal Article
Directed Self-Assembly with Gallic Acid Provides First Phenolic Acid Cocrystals for the Antiviral Drug Acyclovir toward Increasing Pharmaceutical Features and Synergy: A Theoretical and Experimental Integration Research
Bu, Fan-Zhi, Yu, Yue-Ming, Zhang, Min, Yan, Cui-Wei, Wu, Zhi-Yong, Li, Yan-Tuan
Published in Crystal growth & design (02.08.2023)
Published in Crystal growth & design (02.08.2023)
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Journal Article
The first nano-cocrystal formulation of marine drug cytarabine with uracil based on cocrystal nanonization strategy for long-acting injection exhibiting enhanced antitumor activity
Yu, Yue-Ming, Bu, Fan-Zhi, Meng, Su-Su, Yan, Cui-Wei, Wu, Zhi-Yong, Li, Yan-Tuan
Published in International journal of pharmaceutics (25.09.2023)
Published in International journal of pharmaceutics (25.09.2023)
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Journal Article
Cocrystallization of Amantadine Hydrochloride with Resveratrol: The First Drug–Nutraceutical Cocrystal Displaying Synergistic Antiviral Activity
Wang, Ling-Yang, Zhao, Ming-Yu, Bu, Fan-Zhi, Niu, Yuan-Yuan, Yu, Yue-Ming, Li, Yan-Tuan, Yan, Cui-Wei, Wu, Zhi-Yong
Published in Crystal growth & design (05.05.2021)
Published in Crystal growth & design (05.05.2021)
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Journal Article
Bifonazole caffeate: The first molecular salt of bifonazole with enhanced biopharmaceutical property based on experiments and quantum chemistry research
Bu, Fan-Zhi, Meng, Su-Su, Wang, Ling-Yang, Wu, Zhi-Yong, Li, Yan-Tuan
Published in Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy (05.09.2024)
Published in Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy (05.09.2024)
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Journal Article
Cocrystallization-Driven Double-Optimized Stratagem toward Directional Self-Assembly for the First Ternary Salt Cocrystal of Cardiotonic Drug Milrinone with Different Phenolic Acids Exhibits Optimal In Vitro/Vivo Biopharmaceutical Peculiarities
Meng, Su-Su, Yu, Yue-Ming, Bu, Fan-Zhi, Yan, Cui-Wei, Wu, Zhi-Yong, Li, Yan-Tuan
Published in Molecular pharmaceutics (03.07.2023)
Published in Molecular pharmaceutics (03.07.2023)
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Journal Article
An integrated experimental and theoretical research on ternary salt-cocrystal of anti-heart failure medicine milrinone with different substituted benzoic acids
Bu, Fan-Zhi, Meng, Su-Su, Wang, Ling-Yang, Wu, Zhi-Yong, Li, Yan-Tuan
Published in Journal of molecular structure (15.05.2024)
Published in Journal of molecular structure (15.05.2024)
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Journal Article
Cocrystallization with nutrient ferulic acid towards reducing the dissolubility behaviors of antifungal drug 5-fluorocytosine: An integrated theoretical and experimental case research
Bu, Fan-Zhi, Yu, Yue-Ming, Shen, Yu-Li, Wu, Zhi-Yong, Li, Yan-Tuan
Published in Journal of molecular structure (05.03.2023)
Published in Journal of molecular structure (05.03.2023)
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Journal Article
A novel crystalline molecular salt of sulfamethoxazole and amantadine hybridizing antiviral-antibacterial dual drugs with optimal in vitro/vivo pharmaceutical properties
Wang, Ling-Yang, Bu, Fan-Zhi, Yu, Yue-Ming, Niu, Yuan-Yuan, Li, Yan-Tuan, Yan, Cui-Wei, Wu, Zhi-Yong
Published in European journal of pharmaceutical sciences (01.08.2021)
Published in European journal of pharmaceutical sciences (01.08.2021)
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Journal Article
The comparison researches of cis/trans-butenedioic acids in regulating solid crystalline forms and improving pharmaceutical properties of antifungal drug econazole
Wu, Meng-Yao, Bu, Fan-Zhi, Yu, Yu, Yu, Yue-Ming, Wu, Zhi-Yong, Yan, Cui-Wei, Li, Yan-Tuan
Published in Journal of molecular structure (05.09.2022)
Published in Journal of molecular structure (05.09.2022)
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Journal Article
Cocrystallization-driven self-assembly with vanillic acid offers a new opportunity for surmounting fast and excessive absorption issues of antifungal drug 5-fluorocytosine: a combined theoretical and experimental research
Bu, Fan-Zhi, Yu, Yue-Ming, Shen, Yu-Li, Liu, Lu, Yan, Cui-Wei, Wu, Zhi-Yong, Li, Yan-Tuan
Published in CrystEngComm (12.04.2022)
Published in CrystEngComm (12.04.2022)
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Journal Article
The molecular salt of pyrimethamine and fenbufen for enhancing dissolubility via an assisted efficacy-increasing approach of dual-drug salt formation: A combined study including theory analysis and experiment validation
Shen, Yu-Li, Bu, Fan-Zhi, Yu, Yue-Ming, Meng, Su-Su, Wu, Zhi-Yong, Yan, Cui-Wei, Li, Yan-Tuan
Published in Journal of molecular structure (15.07.2023)
Published in Journal of molecular structure (15.07.2023)
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Journal Article
Design, synthesis, crystal structure and in vitro cytotoxic properties of a novel Schiff base derived from indole and biphenyl
Bu, Fan Zhi, Tan, Xue Jie, Xing, Dian Xiang, Wang, Chao
Published in Acta crystallographica. Section C, Crystal structure communications (01.07.2017)
Published in Acta crystallographica. Section C, Crystal structure communications (01.07.2017)
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Journal Article