AB0506 Identification of a Gene Signature and Response Biomarkers in Circulating Leukocytes of RA Patients After Treatment with the JAK1-Selective Inhibitor Filgotinib (GLPG0634)
Ongenaert, M., Dupont, S., Vayssière, B., Meuleners, L., Brys, R., Galien, R.
Published in Annals of the rheumatic diseases (01.06.2015)
Published in Annals of the rheumatic diseases (01.06.2015)
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Journal Article
THU0138 Glpg0634m1, A Major Metabolite of the Jak1-Selective Inhibitor Glpg0634, is Also Jak1-Selective and Efficient in the Rat CIA Model
Belleville-Da-Costa, C., Merciris, D., Vayssière, B., Houvenaghel, N., Monjardet, A., Lepescheux, L., Dupont, S., Christophe, T., Borgonovi, M., Clément-Lacroix, P., Menet, C., Van Rompaey, L., Brys, R., Galien, R.
Published in Annals of the rheumatic diseases (01.06.2014)
Published in Annals of the rheumatic diseases (01.06.2014)
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Journal Article
Improved sRANKL mouse model as a tool to rapidly evaluate treatment-induced increases in bone mass
Gaillard, V, Meurisse, S, Saint-Marc, C, Domaingue, P, Mollat, P, Brys, R
Published in Bone (New York, N.Y.) (01.05.2012)
Published in Bone (New York, N.Y.) (01.05.2012)
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THU0116 Biological Effects of the JAK1 Selective Inhibitor GLPG0634 on Inflammation Markers in Arthritic Mice
Vayssiere, B., de Vos, S., Merciris, D., Auberval, M., Dupont, S., Vandeghinste, N., Lepescheux, L., Clement-Lacroix, P., Delerive, P., van Rompaey, L., Brys, R., Galien, R.
Published in Annals of the rheumatic diseases (01.06.2013)
Published in Annals of the rheumatic diseases (01.06.2013)
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Journal Article
350 IRAK4 drives pathogenic processes in inflammatory skin diseases
Jargosch, M., Lavazais, S., Ohm, F., Jagerschmidt, C., Fallon, P., Clément-Lacroix, P., Lauffer, F., Brys, R., Eyerich, K.
Published in Journal of investigative dermatology (01.12.2022)
Published in Journal of investigative dermatology (01.12.2022)
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Geographic variation in floral traits and the capacity of autonomous selfing across allopatric and sympatric populations of two closely related Centaurium species
Schouppe, Dorien, Brys, Rein, Vallejo-Marin, Mario, Jacquemyn, Hans
Published in Scientific reports (21.04.2017)
Published in Scientific reports (21.04.2017)
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Journal Article
IRAK4 inhibition dampens pathogenic processes driving inflammatory skin diseases
Lavazais, Stéphanie, Jargosch, Manja, Dupont, Sonia, Labéguère, Frédéric, Menet, Christel, Jagerschmidt, Catherine, Ohm, Frenz, Kupcsik, Laszlo, Parent, Isabelle, Cottereaux, Céline, Marsais, Florence, Oste, Line, Van de Water, An, Christophe, Thierry, De Vos, Steve, Fallon, Padraic, Lauffer, Felix, Clément-Lacroix, Philippe, Eyerich, Kilian, Brys, Reginald
Published in Science translational medicine (15.02.2023)
Published in Science translational medicine (15.02.2023)
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THU-461 - Pharmacological inhibition of the medium chain fatty acid receptor GPR84 reduces myeloid cell in filtration into injured liver and ameliorates steatohepatitis and fibrosis
Puengel, T., De Vos, S., Krenkel, O., Pujuguet, P., Auberval, M., Marsais, F., Shoji, K.F., Saniere, L., Trautwein, C., Brys, R., Tacke, F.
Published in Journal of hepatology (01.04.2018)
Published in Journal of hepatology (01.04.2018)
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Journal Article
Pharmacological inhibition of the medium chain fatty acid receptor GPR84 reduces myeloid cell in filtration into injured liver and ameliorates steatohepatitis and fibrosis
Puengel, T., De Vos, S., Krenkel, O., Pujuguet, P., Auberval, M., Marsais, F., Shoji, K.F., Saniere, L., Trautwein, C., Brys, R., Tacke, F.
Published in Journal of hepatology (01.04.2018)
Published in Journal of hepatology (01.04.2018)
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Journal Article