Structure-Based Discovery of Substituted 4,5′-Bithiazoles as Novel DNA Gyrase Inhibitors
Brvar, Matjaž, Perdih, Andrej, Renko, Miha, Anderluh, Gregor, Turk, Dušan, Solmajer, Tom
Published in Journal of medicinal chemistry (26.07.2012)
Published in Journal of medicinal chemistry (26.07.2012)
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Discovery of 4,5,6,7-Tetrahydrobenzo[1,2‑d]thiazoles as Novel DNA Gyrase Inhibitors Targeting the ATP-Binding Site
Tomašič, Tihomir, Katsamakas, Sotirios, Hodnik, Žiga, Ilaš, Janez, Brvar, Matjaž, Solmajer, Tom, Montalvão, Sofia, Tammela, Päivi, Banjanac, Mihailo, Ergović, Gabrijela, Anderluh, Marko, Mašič, Lucija Peterlin, Kikelj, Danijel
Published in Journal of medicinal chemistry (23.07.2015)
Published in Journal of medicinal chemistry (23.07.2015)
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Discovery of substituted oxadiazoles as a novel scaffold for DNA gyrase inhibitors
Jakopin, Žiga, Ilaš, Janez, Barančoková, Michaela, Brvar, Matjaž, Tammela, Päivi, Sollner Dolenc, Marija, Tomašič, Tihomir, Kikelj, Danijel
Published in European journal of medicinal chemistry (21.04.2017)
Published in European journal of medicinal chemistry (21.04.2017)
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Journal Article
New N-phenyl-4,5-dibromopyrrolamides and N-Phenylindolamides as ATPase inhibitors of DNA gyrase
Zidar, Nace, Tomašič, Tihomir, Macut, Helena, Sirc, Anja, Brvar, Matjaž, Montalvão, Sofia, Tammela, Päivi, Ilaš, Janez, Kikelj, Danijel
Published in European journal of medicinal chemistry (19.07.2016)
Published in European journal of medicinal chemistry (19.07.2016)
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Journal Article
In silico discovery and biophysical evaluation of novel 5-(2-hydroxybenzylidene) rhodanine inhibitors of DNA gyrase B
Brvar, Matjaž, Perdih, Andrej, Hodnik, Vesna, Renko, Miha, Anderluh, Gregor, Jerala, Roman, Solmajer, Tom
Published in Bioorganic & medicinal chemistry (15.04.2012)
Published in Bioorganic & medicinal chemistry (15.04.2012)
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Journal Article
N‑Phenyl-4,5-dibromopyrrolamides and N‑Phenylindolamides as ATP Competitive DNA Gyrase B Inhibitors: Design, Synthesis, and Evaluation
Zidar, Nace, Macut, Helena, Tomašič, Tihomir, Brvar, Matjaž, Montalvão, Sofia, Tammela, Päivi, Solmajer, Tom, Peterlin Mašič, Lucija, Ilaš, Janez, Kikelj, Danijel
Published in Journal of medicinal chemistry (13.08.2015)
Published in Journal of medicinal chemistry (13.08.2015)
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Journal Article
Linker-switch approach towards new ATP binding site inhibitors of DNA gyrase B
Jukič, Marko, Ilaš, Janez, Brvar, Matjaž, Kikelj, Danijel, Cesar, Jožko, Anderluh, Marko
Published in European journal of medicinal chemistry (05.01.2017)
Published in European journal of medicinal chemistry (05.01.2017)
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Molecular Mechanism of Action for Allosteric Modulators and Agonists in CC-chemokine Receptor 5 (CCR5)
Karlshøj, Stefanie, Amarandi, Roxana Maria, Larsen, Olav, Daugvilaite, Viktorija, Steen, Anne, Brvar, Matjaž, Pui, Aurel, Frimurer, Thomas Michael, Ulven, Trond, Rosenkilde, Mette Marie
Published in The Journal of biological chemistry (23.12.2016)
Published in The Journal of biological chemistry (23.12.2016)
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Discovery of Mono- and Disubstituted 1H-Pyrazolo[3,4]pyrimidines and 9H-Purines as Catalytic Inhibitors of Human DNA Topoisomerase IIα
Pogorelčnik, Barbara, Brvar, Matjaž, Žegura, Bojana, Filipič, Metka, Solmajer, Tom, Perdih, Andrej
Published in ChemMedChem (01.02.2015)
Published in ChemMedChem (01.02.2015)
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Receptor structure-based discovery of non-metabolite agonists for the succinate receptor GPR91
Trauelsen, Mette, Rexen Ulven, Elisabeth, Hjorth, Siv A, Brvar, Matjaz, Monaco, Claudia, Frimurer, Thomas M, Schwartz, Thue W
Published in Molecular metabolism (Germany) (01.12.2017)
Published in Molecular metabolism (Germany) (01.12.2017)
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Design, Synthesis, and Evaluation of Novel Tyrosine‐Based DNA Gyrase B Inhibitors
Cotman, Andrej E., Trampuž, Marko, Brvar, Matjaž, Kikelj, Danijel, Ilaš, Janez, Peterlin‐Mašič, Lucija, Montalvão, Sofia, Tammela, Päivi, Frlan, Rok
Published in Archiv der Pharmazie (Weinheim) (01.08.2017)
Published in Archiv der Pharmazie (Weinheim) (01.08.2017)
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Discovery of the first inhibitors of bacterial enzyme d-aspartate ligase from Enterococcus faecium (Aslfm)
Škedelj, Veronika, Perdih, Andrej, Brvar, Matjaž, Kroflič, Ana, Dubbée, Vincent, Savage, Victoria, O'Neill, Alex J., Solmajer, Tom, Bešter-Rogač, Marija, Blanot, Didier, Hugonnet, Jean-Emmanuel, Magnet, Sophie, Arthur, Michel, Mainardi, Jean-Luc, Stojan, Jure, Zega, Anamarija
Published in European journal of medicinal chemistry (01.09.2013)
Published in European journal of medicinal chemistry (01.09.2013)
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Structure–Activity Relationship Studies of Tetrahydroquinolone Free Fatty Acid Receptor 3 Modulators
Ulven, Elisabeth Rexen, Quon, Tezz, Sergeev, Eugenia, Barki, Natasja, Brvar, Matjaz, Hudson, Brian D, Dutta, Palash, Hansen, Anders Højgaard, Bielefeldt, Line Ø, Tobin, Andrew B, McKenzie, Christine J, Milligan, Graeme, Ulven, Trond
Published in Journal of medicinal chemistry (09.04.2020)
Published in Journal of medicinal chemistry (09.04.2020)
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Journal Article
Structure-Activity Investigations and Optimisations of Non-metabolite Agonists for the Succinate Receptor 1
Rexen Ulven, Elisabeth, Trauelsen, Mette, Brvar, Matjaz, Lückmann, Michael, Bielefeldt, Line Ø., Jensen, Lisa K. I., Schwartz, Thue W., Frimurer, Thomas M.
Published in Scientific reports (03.07.2018)
Published in Scientific reports (03.07.2018)
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Journal Article
Discovery of Mono- and Disubstituted 1H-Pyrazolo[3,4]pyrimidines and 9H-Purines as Catalytic Inhibitors of Human DNA TopoisomeraseII alpha
Pogorelcnik, Barbara, Brvar, Matjaz, egura, Bojana, Filipic, Metka, Solmajer, Tom, Perdih, Andrej
Published in ChemMedChem (01.02.2015)
Published in ChemMedChem (01.02.2015)
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Journal Article
Discovery of Mono- and Disubstituted 1H-Pyrazolo[3,4]pyrimidines and 9H-Purines as Catalytic Inhibitors of Human DNA TopoisomeraseII[alpha]
Pogorelcnik, Barbara, Brvar, Matjaz, egura, Bojana, Filipic, Metka, Solmajer, Tom, Perdih, Andrej
Published in ChemMedChem (01.02.2015)
Published in ChemMedChem (01.02.2015)
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Selective Allosteric Modulation of N‑Terminally Cleaved, but Not Full Length CCL3 in CCR1
Larsen, Olav, Lückmann, Michael, van der Velden, Wijnand J. C, Oliva-Santiago, Marta, Brvar, Matjaz, Ulven, Trond, Frimurer, Thomas M, Karlshøj, Stefanie, Rosenkilde, Mette M
Published in ACS pharmacology & translational science (13.12.2019)
Published in ACS pharmacology & translational science (13.12.2019)
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GPR120 조절제로서의 테트라하이드로-벤조[d]아제핀 유도체
BRVAR MATJAZ, RIGBY AARON, SMYTH DON, BROWN JANE, HANSEN STEFFEN V. F, CONNOLLY STEPHEN, MILNE GAVIN, SHIMPUKADE BHARAT, THOMAS GERARD, ULVEN TROND
Year of Publication 20.12.2019
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Year of Publication 20.12.2019
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