matières, en continuité
Marchand, Bruno
Published in Cahiers de la recherche architecturale, urbaine et paysagère (24.12.2021)
Published in Cahiers de la recherche architecturale, urbaine et paysagère (24.12.2021)
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Journal Article
Acetyl-CoA carboxylase inhibition disrupts metabolic reprogramming during hepatic stellate cell activation
Bates, Jamie, Vijayakumar, Archana, Ghoshal, Sarani, Marchand, Bruno, Yi, Saili, Kornyeyev, Dmytro, Zagorska, Anna, Hollenback, David, Walker, Katie, Liu, Kathy, Pendem, Swetha, Newstrom, David, Brockett, Robert, Mikaelian, Igor, Kusam, Saritha, Ramirez, Ricardo, Lopez, David, Li, Li, Fuchs, Bryan C., Breckenridge, David G.
Published in Journal of hepatology (01.10.2020)
Published in Journal of hepatology (01.10.2020)
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Journal Article
Structural basis of HIV inhibition by translocation-defective RT inhibitor 4′-ethynyl-2-fluoro-2′-deoxyadenosine (EFdA)
Li Salie, Zhe, Kirby, Karen A., Michailidis, Eleftherios, Marchand, Bruno, Singh, Kamalendra, Rohan, Lisa C., Kodama, Eiichi N., Mitsuya, Hiroaki, Parniak, Michael A., Sarafianos, Stefan G.
Published in Proceedings of the National Academy of Sciences - PNAS (16.08.2016)
Published in Proceedings of the National Academy of Sciences - PNAS (16.08.2016)
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Journal Article
Structure and Function of HIV-1 Reverse Transcriptase: Molecular Mechanisms of Polymerization and Inhibition
Sarafianos, Stefan G., Marchand, Bruno, Das, Kalyan, Himmel, Daniel M., Parniak, Michael A., Hughes, Stephen H., Arnold, Eddy
Published in Journal of molecular biology (23.01.2009)
Published in Journal of molecular biology (23.01.2009)
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Journal Article
Mechanism of nucleic acid unwinding by SARS-CoV helicase
Adedeji, Adeyemi O, Marchand, Bruno, Te Velthuis, Aartjan J W, Snijder, Eric J, Weiss, Susan, Eoff, Robert L, Singh, Kamalendra, Sarafianos, Stefan G
Published in PloS one (15.05.2012)
Published in PloS one (15.05.2012)
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Journal Article
Mechanism of Inhibition of HIV-1 Reverse Transcriptase by 4′-Ethynyl-2-fluoro-2′-deoxyadenosine Triphosphate, a Translocation-defective Reverse Transcriptase Inhibitor
Michailidis, Eleftherios, Marchand, Bruno, Kodama, Eiichi N., Singh, Kamlendra, Matsuoka, Masao, Kirby, Karen A., Ryan, Emily M., Sawani, Ali M., Nagy, Eva, Ashida, Noriyuki, Mitsuya, Hiroaki, Parniak, Michael A., Sarafianos, Stefan G.
Published in The Journal of biological chemistry (18.12.2009)
Published in The Journal of biological chemistry (18.12.2009)
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Journal Article
Biochemical Mechanism of HIV-1 Resistance to Rilpivirine
Singh, Kamalendra, Marchand, Bruno, Rai, Devendra K., Sharma, Bechan, Michailidis, Eleftherios, Ryan, Emily M., Matzek, Kayla B., Leslie, Maxwell D., Hagedorn, Ariel N., Li, Zhe, Norden, Pieter R., Hachiya, Atsuko, Parniak, Michael A., Xu, Hong-Tao, Wainberg, Mark A., Sarafianos, Stefan G.
Published in The Journal of biological chemistry (02.11.2012)
Published in The Journal of biological chemistry (02.11.2012)
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Journal Article
Combinations of an acetyl CoA carboxylase inhibitor with hepatic lipid modulating agents do not augment antifibrotic efficacy in preclinical models of NASH and fibrosis
Vijayakumar, Archana, Okesli‐Armlovich, Ayse, Wang, Ting, Olson, Isabel, Seung, Minji, Kusam, Saritha, Hollenback, David, Mahadevan, Sangeetha, Marchand, Bruno, Toteva, Maria, Breckenridge, David G., Trevaskis, James L., Bates, Jamie
Published in Hepatology communications (01.09.2022)
Published in Hepatology communications (01.09.2022)
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Journal Article
Effects of Substitutions at the 4′ and 2 Positions on the Bioactivity of 4′-Ethynyl-2-Fluoro-2′-Deoxyadenosine
KIRBY, Karen A, MICHAILIDIS, Eleftherios, HUGHES, Stephen H, MITSUYA, Hiroaki, PARNIAK, Michael A, SARAFIANOSA, Stefan G, FETTERLY, Tracy L, STEINBACH, Musetta A, SINGH, Kamalendra, MARCHAND, Bruno, LESLIE, Maxwell D, HAGEDOM, Ariel N, KODAMA, Eiichi N, MARQUEZ, Victor E
Published in Antimicrobial Agents and Chemotherapy (01.12.2013)
Published in Antimicrobial Agents and Chemotherapy (01.12.2013)
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Journal Article
The Pyrophosphate Analogue Foscarnet Traps the Pre-translocational State of HIV-1 Reverse Transcriptase in a Brownian Ratchet Model of Polymerase Translocation
Marchand, Bruno, Tchesnokov, Egor P., Götte, Matthias
Published in The Journal of biological chemistry (02.02.2007)
Published in The Journal of biological chemistry (02.02.2007)
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Journal Article
The N348I Mutation at the Connection Subdomain of HIV-1 Reverse Transcriptase Decreases Binding to Nevirapine
Schuckmann, Matthew M., Marchand, Bruno, Hachiya, Atsuko, Kodama, Eiichi N., Kirby, Karen A., Singh, Kamalendra, Sarafianos, Stefan G.
Published in The Journal of biological chemistry (03.12.2010)
Published in The Journal of biological chemistry (03.12.2010)
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Journal Article
Evaluation of Combinations of 4′-Ethynyl-2-Fluoro-2′-Deoxyadenosine with Clinically Used Antiretroviral Drugs
HACHIYA, Atsuko, REEVE, Aaron B, MITSUYA, Hiroaki, PARNIAK, Michael A, SARAFIANOS, Stefan G, MARCHAND, Bruno, MICHAILIDIS, Eleftherios, YEE TSUEY ONG, KIRBY, Karen A, LESLIE, Maxwell D, OKA, Shinichi, KODAMA, Eiichi N, ROHAN, Lisa C
Published in Antimicrobial Agents and Chemotherapy (01.09.2013)
Published in Antimicrobial Agents and Chemotherapy (01.09.2013)
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Journal Article
Structural and Inhibition Studies of the RNase H Function of Xenotropic Murine Leukemia Virus-Related Virus Reverse Transcriptase
KIRBY, Karen A, MARCHAND, Bruno, SINGH, Kamalendra, ZHENGQIANG WANG, PARNIAK, Michael A, SARAFIANOS, Stefan G, YEE TSUEY ONG, NDONGWE, Tanyaradzwa P, HACHIYA, Atsuko, MICHAILIDIS, Eleftherios, LESLIE, Maxwell D, SIETSEMA, Daniel V, FETTERLY, Tracy L, DORST, Christopher A
Published in Antimicrobial Agents and Chemotherapy (01.04.2012)
Published in Antimicrobial Agents and Chemotherapy (01.04.2012)
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Journal Article
Hypersusceptibility mechanism of Tenofovir-resistant HIV to EFdA
Michailidis, Eleftherios, Ryan, Emily M, Hachiya, Atsuko, Kirby, Karen A, Marchand, Bruno, Leslie, Maxwell D, Huber, Andrew D, Ong, Yee T, Jackson, Jacob C, Singh, Kamalendra, Kodama, Eiichi N, Mitsuya, Hiroaki, Parniak, Michael A, Sarafianos, Stefan G
Published in Retrovirology (24.06.2013)
Published in Retrovirology (24.06.2013)
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Journal Article
Structural Aspects of Drug Resistance and Inhibition of HIV-1 Reverse Transcriptase
Singh, Kamalendra, Marchand, Bruno, Kirby, Karen A, Michailidis, Eleftherios, Sarafianos, Stefan G
Published in Viruses (11.02.2010)
Published in Viruses (11.02.2010)
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Journal Article
Book Review
Structural basis of clade-specific HIV-1 neutralization by humanized anti-V3 monoclonal antibody KD-247
Kirby, Karen A, Ong, Yee Tsuey, Hachiya, Atsuko, Laughlin, Thomas G, Chiang, Leslie A, Pan, Yun, Moran, Jennifer L, Marchand, Bruno, Singh, Kamalendra, Gallazzi, Fabio, Quinn, Thomas P, Yoshimura, Kazuhisa, Murakami, Toshio, Matsushita, Shuzo, Sarafianos, Stefan G
Published in The FASEB journal (01.01.2015)
Published in The FASEB journal (01.01.2015)
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Journal Article
HIV-1 Reverse Transcriptase (RT) Polymorphism 172K Suppresses the Effect of Clinically Relevant Drug Resistance Mutations to Both Nucleoside and Non-nucleoside RT Inhibitors
Hachiya, Atsuko, Marchand, Bruno, Kirby, Karen A., Michailidis, Eleftherios, Tu, Xiongying, Palczewski, Krzysztof, Ong, Yee Tsuey, Li, Zhe, Griffin, Daniel T., Schuckmann, Matthew M., Tanuma, Junko, Oka, Shinichi, Singh, Kamalendra, Kodama, Eiichi N., Sarafianos, Stefan G.
Published in The Journal of biological chemistry (24.08.2012)
Published in The Journal of biological chemistry (24.08.2012)
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Journal Article
Inhibitors of Foot and Mouth Disease Virus Targeting a Novel Pocket of the RNA-Dependent RNA Polymerase
Durk, Ryan C, Singh, Kamalendra, Cornelison, Ceili A, Rai, Devendra K, Matzek, Kayla B, Leslie, Maxwell D, Schafer, Elizabeth, Marchand, Bruno, Adedeji, Adeyemi, Michailidis, Eleftherios, Dorst, Christopher A, Moran, Jennifer, Pautler, Christie, Rodriguez, Luis L, McIntosh, Mark A, Rieder, Elizabeth
Published in PloS one (21.12.2010)
Published in PloS one (21.12.2010)
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Journal Article