Structure of a hepatitis C virus RNA domain in complex with a translation inhibitor reveals a binding mode reminiscent of riboswitches
Dibrov, Sergey M, Ding, Kejia, Brunn, Nicholas D, Parker, Matthew A, Bergdahl, B. Mikael, Wyles, David L, Hermann, Thomas
Published in Proceedings of the National Academy of Sciences - PNAS (03.04.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (03.04.2012)
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Journal Article
Analysis of mRNA recognition by human thymidylate synthase
Brunn, Nicholas D, Dibrov, Sergey M, Kao, Melody B, Ghassemian, Majid, Hermann, Thomas
Published in Bioscience reports (01.01.2014)
Published in Bioscience reports (01.01.2014)
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Journal Article
Hepatitis C virus translation inhibitors targeting the internal ribosomal entry site
Dibrov, Sergey M, Parsons, Jerod, Carnevali, Maia, Zhou, Shu, Rynearson, Kevin D, Ding, Kejia, Garcia Sega, Emily, Brunn, Nicholas D, Boerneke, Mark A, Castaldi, Maria P, Hermann, Thomas
Published in Journal of medicinal chemistry (13.03.2014)
Published in Journal of medicinal chemistry (13.03.2014)
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Journal Article
Screening for inhibitors of the hepatitis C virus internal ribosome entry site RNA
Zhou, Shou, Rynearson, Kevin D., Ding, Kejia, Brunn, Nicholas D., Hermann, Thomas
Published in Bioorganic & medicinal chemistry (15.10.2013)
Published in Bioorganic & medicinal chemistry (15.10.2013)
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Journal Article
The Role of Anti-Drug Antibodies in the Pharmacokinetics, Disposition, Target Engagement, and Efficacy of a GITR Agonist Monoclonal Antibody in Mice
Brunn, Nicholas D, Mauze, Smita, Gu, Danling, Wiswell, Derek, Ueda, Roanna, Hodges, Douglas, Beebe, Amy M, Zhang, Shuli, Escandón, Enrique
Published in The Journal of pharmacology and experimental therapeutics (01.03.2016)
Published in The Journal of pharmacology and experimental therapeutics (01.03.2016)
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Journal Article
Targeting a Regulatory Element in Human Thymidylate Synthase mRNA
Brunn, Nicholas D., Garcia Sega, Emily, Kao, Melody B., Hermann, Thomas
Published in Chembiochem : a European journal of chemical biology (21.12.2012)
Published in Chembiochem : a European journal of chemical biology (21.12.2012)
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Journal Article
Hepatitis C Virus Translation Inhibitors Targeting the Internal Ribosomal Entry Site: Miniperspective
Dibrov, Sergey M., Parsons, Jerod, Carnevali, Maia, Zhou, Shu, Rynearson, Kevin D., Ding, Kejia, Garcia Sega, Emily, Brunn, Nicholas D., Boerneke, Mark A., Castaldi, Maria P., Hermann, Thomas
Published in Journal of medicinal chemistry (13.03.2014)
Published in Journal of medicinal chemistry (13.03.2014)
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Journal Article